| Budget Amount *help |
¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2018: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2017: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2016: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
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| Outline of Final Research Achievements |
Previous studies in thermal biology has only focused on the physiological temperature at macroscopic level. The study supported by this grant was aimed at revealing the dynamics of how heat production occurring at microscopic level spreads from single cell to multi-cellular tissues. More specifically, we achieved to obtain the temperature mapping of tissue samples at high spatial resolution using the developed functional fluorescent thermometer. In addition, we succeeded to visualize the signalling story of thermogenesis in single brown adipocyte.
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