| Budget Amount *help |
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2019: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2018: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2016: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Outline of Final Research Achievements |
We studied the social aspects in the life of plant viruses, and developed a novel method to protect crop plants from viruses. Specifically, we carried out molecular biology experiments and computer simulations to show that cell infection by around 5 genomes is a general phenomenon among plant vi1ruses, and this allows the viruses to exclude free-riders from their populations. We also developed a simulation model for replication of cucumber mosaic virus, which has a three-segmented genome, to explain how the ratio of each segment are balanced during replication and accumulation of segmented viruses. Furthermore, we showed that cucumber mosaic virus has a decision-making system that resembles a majority decision, and developed an artificially modified viral RNA variant that targets this decision making and inhibits the cell-to-cell movement of the virus.
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