| Budget Amount *help |
¥23,920,000 (Direct Cost: ¥18,400,000、Indirect Cost: ¥5,520,000)
Fiscal Year 2019: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2017: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2016: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Outline of Final Research Achievements |
The production of reactive oxygen species (ROS) by RBOHD play central roles in plant immunity. Plants have two types of immune receptors: surface-localized receptors that recognize pathogen-associated molecular patterns (PAMPs) and intracellular receptors recognizing pathogenic effectors. We aimed to clarify the signal transduction from immune receptors to RBOHD activation. Biochemical analyses successfully clarified the novel regulatory mechanisms of PAMP receptors and the co-receptor. Besides, we identified a novel Ca2+ channel required for the activation of RBOHD. We also clarified the transcriptional regulation of RbohD and found a novel regulator of endocytosis of RBOHD. Furthermore, we found the activation mechanism of RBOHD by phosphorylation in plasmodesmata is different from that in other regions. We also found that S343 and S347 of RBOHD are common phosphorylation targets after activation of surface-localized receptors and intracellular receptors.
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