| Budget Amount *help |
¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2018: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
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| Outline of Final Research Achievements |
We elucidated pathological and physiological neural activity of the human cerebral cortex in terms of micro- and macroscopic neural behavior using hybrid electrodes combining macro- and micro electrodes which were specially fabricated for this study. First, we found neurons with increased or decreased firing frequency prior to seizure onsets confirmed by conventional macro electrodes. Second, we decoded uttered vowels by combining three different scales of neural activity and achieved 58.6% decoding accuracy. Third, we clarified that the decoding accuracy using single neurons depends on the number of isolated single neurons. Based on this, we introduced the second and third generation hybrid electrodes, which slightly improved the decoding accuracy (up to 63%).
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