| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2019: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2018: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
In this study, we investigated the applicability of cell-seeded nanofibrous scaffolds to repair the meniscal injury along with the prevention of subsequent cartilage degeneration using an animal model. The cell-seeded nanofibrous scaffolds contributed significantly to the reinforcement of meniscal torn site and exerted a chondroprotective effect, compared with the untreated control groups. Thus, we have demonstrated the feasibility of our technique to repair the meniscal injury, and prevent the progression to osteoarthritis, as a potential tissue engineering method.
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