コホート・生体試料支援プラットフォーム

• Project/Area Number: 16H06277
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
• Allocation Type: Single-year Grants
• Research Institution: The University of Tokyo
• Principal Investigator(Support): 今井 浩三 東京大学, 医科学研究所, 客員教授 (60117603)
• Co-Investigator(Kenkyū-buntansha)(Support): 若井 建志 名古屋大学, 大学院医学系研究科, 教授 (50270989) ; 村上 善則 東京大学, 医科学研究所, 教授 (30182108) ; 松尾 恵太郎 愛知県がんセンター(研究所), がん予防研究分野, 分野長 (80393122) ; 三上 春夫 千葉県がんセンター(研究所), がん予防センター, 部長 (10332355) ; 鈴木 貞夫 名古屋市立大学, 大学院医学研究科, 教授 (20226509) ; 喜多 義邦 敦賀市立看護大学, 看護学部, 准教授 (30147524) ; 渡辺 能行 (渡邊 能行) 京都府立医科大学, 大学院医学研究科, 教授 (00191809) ; 田中 恵太郎 佐賀大学, 医学部, 教授 (50217022) ; 嶽崎 俊郎 鹿児島大学, 医歯学域医学系, 教授 (50227013) ; 栗木 清典 静岡県立大学, 食品栄養科学部, 教授 (20543705) ; 古庄 憲浩 九州大学, 大学院医学研究院, 准教授 (10346786) ; 有澤 孝吉 徳島大学, 大学院医歯薬学研究部, 教授 (30203384) ; 玉腰 暁子 北海道大学, 大学院医学研究院, 教授 (90236737) ; 今田 恒夫 山形大学, 大学院医学系研究科, 教授 (60333952) ; 武林 亨 慶應義塾大学, 医学部, 教授 (30265780) ; 三浦 克之 滋賀医科大学, 医学部, 教授 (90257452) ; 成松 宏人 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所・がん予防・情報学部, 部長 (50524419) ; 鈴木 康司 藤田保健衛生大学, 保健学研究科, 教授 (60288470) ; 村山 繁雄 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (50183653) ; 高尾 昌樹 (高雄 昌樹) 公益財団法人脳血管研究所, 美原記念病院, 研究員 (50245487) ; 赤津 裕康 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員 (00399734) ; 齊藤 祐子 国立研究開発法人国立精神・神経医療研究センター, 病院臨床検査科, 医長 (60344066) ; 矢部 博興 福島県立医科大学, 医学部, 教授 (60210316) ; 中杤 昌弘 名古屋大学, 医学部附属病院, 病院講師 (10559983) ; 清水 厚志 岩手医科大学, いわて東北メディカル・メガバンク機構, 特命教授 (30327655) ; 醍醐 弥太郎 東京大学, 医科学研究所, 特任教授 (30345029) ; 高橋 隆 名古屋大学, 大学院医学系研究科, 教授 (50231395) ; 宮城 洋平 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所・がん分子病態学部, 総括部長 (00254194) ; 渡邉 俊樹 東京大学, 名誉教授 (30182934) ; 安井 寛 東京大学, 医科学研究所, 特任准教授 (40448593) ; 田中 英夫 愛知県がんセンター研究所, 疫学・予防部, 部長 (60470168) ; 内藤 真理子 名古屋大学, 大学院医学系研究科, 准教授 (10378010) ; 大中 佳三 九州大学, 医学研究院, 講師 (30325518) ; 森 満 札幌医科大学, 医学部, 教授 (50175634) ; 川崎 良 山形大学, 大学院医学系研究科, 准教授 (70301067)
• Project Period (FY): 2016 – 2021
• Project Status: Granted (Fiscal Year 2018)
• Budget Amount: ¥2,276,040,000 (Direct Cost: ¥1,750,800,000、Indirect Cost: ¥525,240,000); Fiscal Year 2018: ¥379,340,000 (Direct Cost: ¥291,800,000、Indirect Cost: ¥87,540,000); Fiscal Year 2017: ¥379,340,000 (Direct Cost: ¥291,800,000、Indirect Cost: ¥87,540,000); Fiscal Year 2016: ¥379,340,000 (Direct Cost: ¥291,800,000、Indirect Cost: ¥87,540,000)
• Keywords: 生体試料支援 / コホート / 臨床検体 / 一般健常人 / 大規模ゲノム解析 / 大規模ゲノム解析・オミックス解析 / オミックス解析

Outline of Annual Research Achievements

①総括支援活動 : 10.2万名の健常人コホートにより、経時的生活情報とともに血清、DNA等のバイオリソースを、また、がん組織、脳疾患や高齢者の脳組織等から、倫理面に十分配慮された、1万件に達する生体試料を、それぞれ収集してきた。これらの研究基盤リソースを提供するとともに、これをさらに全国規模で発展継続させ、生命科学研究者の独創的な基盤的研究に貢献しようとする、この分野における我が国最大規模の支援である。当プラットフォームの支援活動自体は国民一人ひとりとの関わりが強い活動であることから、総括支援活動においては、その支援内容や知見について広く市民の理解を得られるよう、青少年を含む一般市民に向けた公開講座を、シンポジウム等とならんで首都圏以外の各地でも積極的に開催してきた。
②コホートによるバイオリソース支援活動 : 従来の血清、血漿、DNA、生活習慣・健診データ、ゲノムワイド関連解析(GWAS)用タイピングデータに加え、追跡調査で判明したがん罹患症例についても、GWAS用タイピングを開始し、研究支援準備を進めた。
③ブレインリソースの整備と活用支援 : ブレインバンク生前ドナー登録を剖検がほぼ零の沖縄に拡大した。RIN、apoE genotypingによるリソース品質管理を生前同意登録全例に拡大した。広島大学ブレインバンク拠点構築に着手した。
④生体試料による支援活動 : 205課題に生体機能分子の高感度解析・技術支援と連携構築支援を実施した。135課題にがん試料・情報(組織、血液)を提供、5,513試料を収集。解析支援・連携支援・試料支援体制を強化。普及・啓発講演を実施した。

Current Status of Research Progress

1: Research has progressed more than it was originally planned.

Reason

①総括支援活動 : これまで扱ってこなかった関東、東北、北海道などのコホートも加え、名実ともに我が国を代表するバイオリソースに育ちつつある。また、一般市民に対する公開講座等を首都圏以外の各地で積極的に開催して、国民の理解を得て進めようとしている。
②コホートによるバイオリソース支援活動 : 現在実施中の大規模コホート研究(日本多施設共同コホート研究、参加者10.2万人)および既存コホート研究からの生体試料、データにより241件の研究支援を実施、77編の論文が出版された。日本多施設共同コホート研究では、第二次調査、疾病罹患・死亡調査を継続し、生体試料、データを提供できる体制を発展させた。さらに今後の研究支援のため、追跡調査で判明したがん罹患症例のGWAS用タイピングを開始した。
③ブレインリソースの整備と活用支援 : 沖縄は文化的理由により剖検が極めて得られにくいが、生前同意登録による疾患の根治療法への希望から、これまで剖検が零だった沖縄型神経原性萎縮症リソース構築を行うことが出来たのは、想定外であった。また縦割り構造を原則とする本邦において、広島大学において生前同意登録神経難病症例のリソース構築のため、脳神経内科と病理の協力体制の下、代表者がリソース構築を行うことができたことも、想定外であった。
④生体試料による支援活動 : 最新の生命科学研究の動向を踏まえて、新規の高精度分子解析技術による解析支援体制の整備、生体試料バンクのタイムスタンプ記録による国際標準化を視野に入れた収集体制の整備、組織・血液形態学的支援の強化と支援内容・成果の広報・啓発を進めつつ、支援課題数は生体機能分子解析・技術・連携支援および生体試料収集・提供支援ともに平成30年度の研究支援実施計画を上回り、国際的にインパクトのある学術発表に貢献したため。

Strategy for Future Research Activity

①総括支援活動 : 我が国にこれまで存在する他のコホート研究とさらに連携を強め、戦略的に統一された日本のコホート研究となるよう推進する。
②コホートによるバイオリソース支援活動 : 研究支援について、これまで手薄であった社会医学系研究者への広報を強化するため、関連学会での展示に出展することとし、2019年度はまず日本疫学会での展示を実施する。さらにGWAS用タイピングデータ、生活習慣・健診データについては、解析テーマの公募を行い、研究支援件数の増加を図る。また今後の研究支援のため、追跡調査で判明したがん罹患症例のGWAS用タイピングを継続する。
③ブレインリソースの整備と活用支援 : 死後脳リソース品質維持に必須の次世代神経病理診断医育成を目的に、本ブレインバンク拠点を核に神経病理学会認定医コース教育指導医、教育拠点の構築を開始した。大学と関連病院との枠組よりなる教育拠点を基盤に、ブレインバンク拠点を拡大していく。病理解剖の減少には歯止めが変わらない一方、行政解剖は著増している。監察医務院との連携による死後脳リソース構築を、東京に加え大阪においても開始する。
④生体試料による支援活動 : 広汎な生命科学領域における支援依頼者のニーズと技術革新に迅速に対応して支援成果を研究者に還元するため、先進的な分子解析支援技術の向上と導入・強化を進め、より多彩な試料収集と国際水準の質の確保、迅速な提供体制の整備を進める。併せて支援班と先進的研究拠点等との連携、情報共有を強化し、学際的共同研究の構築支援を行う。また、学会や教育の場で研究者や若手向けの普及・啓発活動を展開し、支援対象の裾野を広げる。

Research Products

• [Int'l Joint Research] デューク大学/ユタ大学/南カリフォルニア大学（アメリカ合衆国）
• [Int'l Joint Research] ケンブリッジ大学/エジンバラ大学（イギリス）
• [Int'l Joint Research] クイーンズランド大学（オーストラリア）
• [Int'l Joint Research] 国立がんセンター（韓国）
• [Int'l Joint Research] センメルヴェイス大学（ハンガリー）
• [Int'l Joint Research] ハーバード大学 ダナファーバーがん研究所/シカゴ大学/NIH(アメリカ合衆国)
• [Int'l Joint Research] University of Chicago/NCI/Vanderbilt University(米国)
• [Int'l Joint Research] University of Hong Kong/Shandong Academy of Medical Sciences/Tianjin Medical University Cancer Institute and Hospital(中国)
• [Int'l Joint Research] NHRI, Taiwan/Academia Sinica/National Yang-Ming University(台湾)
• [Int'l Joint Research] Chonnam National University, Korea/Seoul National University College of Medicine/Korea University Anam Hospital(韓国)
• [Int'l Joint Research] Institute of Predictive and Personalized Medicine of Cancer(スペイン)
• [Int'l Joint Research] National University of Singapore/Genome Institute of Singapore(シンガボール)
• [Journal Article] Fracture risk assessment tool (FRAX) and for the diagnosis of osteoporosis in Japanese middle-aged and elderly women : Chiba bone survey. (2020)
  • Author(s): Oka R, Ohira M, Suzuki S, Yoshida T, Koide H, Tanaka T, Tatsuno I.
  • Journal Title: Endocr J Volume: 65 Issue: 2 Pages: 193-202
  • DOI: 10.1507/endocrj.ej17-0331 10.1507/endocrj.EJ17-0331
  • NAID: 130006402991
  • ISSN: 0918-8959, 1348-4540
  • Year and Date: 2020-02-05
  • Peer Reviewed / Open Access
• [Journal Article] Associations of Daily Walking Time With Pneumonia Mortality Among Elderly Individuals With or Without a Medical History of Myocardial Infarction or Stroke : Findings From the Japan Collaborative Cohort Study. (2019)
  • Author(s): Ukawa S, Zhao W, Yatsuya H, Yamagishi K, Tanabe N, Iso H, Tamakoshi A.
  • Journal Title: Journal of Epidemiology Volume: 29 Issue: 6 Pages: 233-237
  • DOI: 10.2188/jea.je20170341 10.2188/jea.JE20170341
  • NAID: 130007660952
  • ISSN: 0917-5040, 1349-9092
  • Year and Date: 2019-06-05
  • Peer Reviewed / Open Access
• [Journal Article] The Prospective Association Between Plasma Concentrations of Cellular Growth Factors and Risk of Heart Failure Mortality in Japanese Population. (2019)
  • Author(s): Eshak ES, Maruyama K, Iso H, Tamakoshi A.
  • Journal Title: Journal of Epidemiology Volume: 29 Issue: 3 Pages: 104-109
  • DOI: 10.2188/jea.je20170123 10.2188/jea.JE20170123
  • NAID: 130007607770
  • ISSN: 0917-5040, 1349-9092
  • Year and Date: 2019-03-05
  • Peer Reviewed
• [Journal Article] Television viewing time, walking time, and risk of type 2 diabetes in Japanese men and women : The Japan Collaborative Cohort Study. (2019)
  • Author(s): Ikehara S, Iso H, Maruyama K, Ukawa S, Tamakoshi A ; Japan Collaborative Cohort Study.
  • Journal Title: Prev Med Volume: 118 Pages: 220-225
  • DOI: 10.1016/j.ypmed.2018.11.006
  • Peer Reviewed
• [Journal Article] No substantial effect of polymorphisms in CPT1B and CPT2 on plasma carnitine levels in Japanese. (CPT遺伝子多型と血漿カルニチン濃度に関する研究) (2019)
  • Author(s): Asahi Hishida, Ryosuke Watanabe, Yuta Hattori, Yoshinaga Okugawa.
  • Journal Title: Nagoya J Med Sci
  • Description: in press
  • Peer Reviewed / Open Access
• [Journal Article] MAO-B binding of 18F-THK5351 to visualize glioblastoma and associated gliosis : an autopsy-confirmed case. (2019)
  • Author(s): (21) Tago T, Toyohara J, Sengoku R, Murayama Y, Ishii K.
  • Journal Title: Cln. Nucl. Med. Volume: 44 Issue: 6 Pages: 1-1
  • DOI: 10.1097/rlu.0000000000002564
  • Peer Reviewed / Open Access
• [Journal Article] Intensity-specific and modified effects of physical activity on serum adiponectin in a middle-aged population (2019)
  • Author(s): Yuichiro Nishida, Yasuki Higaki, Naoto Taguchi, Megumi Hara, Kazuyo Nakamura, Hinako Nanri, Takeshi Imaizumi, Tatsuhiko Sakamoto, Chisato Shimanoe, Mikako Horita, Koichi Shinchi, Keitaro Tanaka
  • Journal Title: Journal of the Endocrine Society Volume: 3 Issue: 1 Pages: 13-26
  • DOI: 10.1210/js.2018-00255
  • Peer Reviewed / Open Access
• [Journal Article] Identification of 28 novel susceptibility loci for type 2 diabetes in the Japanese population (2019)
  • Author(s): Suzuki K, Akiyama M, Horikoshi M, Kamatani Y, Hosoe J, Shojima N, Ishigaki K, Kanai M, Atsushi H, Kadota A, Kuriki K, Naito M, Tannno K, Ishigaki Y, Hirata M, Matsuda K, Iwata N, Ikeda M, Sawada N, Yamaji T, Iwasaki M, Ikegawa S, Okada Y, Maeda S, Murakam
  • Journal Title: Nature Genetics Volume: 51 Issue: 3 Pages: 379-386
  • DOI: 10.1038/s41588-018-0332-4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] GWAS analysis reveals a significant contribution of PSCA to the risk of Helicobacter pylori-induced gastric atrophy (2019)
  • Author(s): Hishida A, Ugai T, Fujii R, Nakatochi M, Wu M C, Ito H, Oze I, Masahiro T, Niwa Y, Nishiyama T, Nakagawa-Senda H, Suzuki S, Koyama T, Matsui D, Watanabe Y, Kawaguchi T, Matsuda F, Momozawa Y, Kubo M, Naito M, Matsuo K, Wakai K
  • Journal Title: Carcinogenesis Volume: -
  • DOI: 10.1093/carcin/bgz016
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. (2019)
  • Author(s): Lawrenson K, Song F, Hazelett DJ, Kar SP, Tyrer J, Phelan CM, Corona RI, Rodriguez-Malavé NI, Seo JH, Adler E, Coetzee SG, Segato F, Fonseca MAS, Amos CI, Carney ME, Chenevix-Trench G, Choi J, Doherty JA, Jia W, Jin GJ, Kim BG, Le ND, Lee J, Li L, Lim BK.
  • Journal Title: Gynecol Oncol Pages: 30133-30137
  • DOI: 10.1016/j.ygyno.2019.02.023
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population. (2019)
  • Author(s): Nishiyama T, Nakatochi M, Goto A, Iwasaki M, Hachiya T, Sutoh Y, Shimizu A, Wang C, Tanaka H, Watanabe M, Hosono A, Tamai Y, Yamada T, Yamaji T, Sawada N, Fukumoto K, Otsuka K, Tanno K, Tomita H, Kojima K, Nagasaki M, Hozawa A, Hishida A, Sasakabe T, Nish
  • Journal Title: Sleep Volume: 印刷中
  • DOI: 10.1093/sleep/zsz046
  • Peer Reviewed / Open Access
• [Journal Article] Eating rate as risk for body mass index and waist circumference obesity with appropriate confounding factors : a cross-sectional analysis of the Shizuoka-Sakuragaoka J-MICC Study (2019)
  • Author(s): Wuren, Endoh K, Kuriki K, Shizuoka-Sakuragaoka J-MICC Study group.
  • Journal Title: Asia Pac J Clin Nutr Volume: 28 Issue: 1 Pages: 79-91
  • Peer Reviewed / Open Access
• [Journal Article] Characterization of the binding of tau imaging ligands to melanine-containing cells : putative off-target-binding site. (2019)
  • Author(s): (20) Tago T. Toyohara J, Harada R, Furumoto S, Okamura N, Kudo Y, Takahashi-Fujigasaki J, Murayama S, Ishii K.
  • Journal Title: Ann. Nucl. Med. Volume: 33 Pages: 1-8
  • DOI: 10.1007/s12149-019-01344-x
  • Description: in press
  • Peer Reviewed / Open Access
• [Journal Article] CD271 is a negative prognostic factor and essential for cell proliferation in lung squamous cell carcinoma (2019)
  • Author(s): Mai Mochizuki, Mao Nakamura, Rie Shibuya, Toshimasa Okazaki, Jiro Abe, Takayuki Nakagawa, Satomi Takahashi, Tomoko Yamazaki, Takayuki Imai, Atsushi Takano, Hiroyuki Ito, Tomoyuki Yokose, Yohei Miyagi, Yataro Daigo, Ikuro Sato, Kennichi Satoh, Kazuo Sugamu
  • Journal Title: Laboratory investigation Volume: -
  • DOI: 10.1038/s41374-019-0246-5
  • Description: in press
  • Peer Reviewed
• [Journal Article] Blood pressure levels and risk of cardiovascular disease mortality among Japanese men and women : The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) (2019)
  • Author(s): Yamagishi K, Sawachi S, Tamakoshi A, Iso H
  • Journal Title: J Hypertens
  • DOI: 10.1097/hjh.0000000000002073
  • Description: in press
  • Peer Reviewed
• [Journal Article] Associations between family factors and body weight gain from 20 years old. (2019)
  • Author(s): Suzuki W, Wuren, Kuriki K.
  • Journal Title: BMC Women's Health. Volume: 19 Issue: 1 Pages: 33-33
  • DOI: 10.1186/s12905-019-0719-0
  • Peer Reviewed / Open Access
• [Journal Article] Association of genetic risk score and chronic kidney disease in a Japanese population. (2019)
  • Author(s): Fujii R, Hishida A, Nakatochi M, Furusyo N, Murata M, Tanaka K, Shimanoe C, Suzuki S, Watanabe M, Kuriyama N, Koyama T, Takezaki T, Shimoshikiryo I, Arisawa K, Katsuura-Kamano S, Takashima N, Turin TC, Kuriki K, Endoh K, Mikami H, Nakamura Y, Oze I, Ito H
  • Journal Title: Nephrology (Carlton) Volume: 印刷中
  • DOI: 10.1111/nep.13479
  • Description: in press
  • Peer Reviewed
• [Journal Article] A role for IL-34 in osteolytic disease of multiple myeloma (2019)
  • Author(s): Baghdadi M, Ishikawa K, Nakanishi S, Murata T, Umeyama Y, Kobayashi T, Kameda Y, Endo H, Wada H, Bogen B, Yamamoto S, Yamaguchi K, Kasahara I, Iwasaki H, Takahata M, Ibata M, Takahashi S, Goto H, Teshima T, Seino K
  • Journal Title: Blood advances Volume: 3 Issue: 4 Pages: 541-551
  • Peer Reviewed / Open Access
• [Journal Article] A genome-wide association study of coping behaviors suggests FBX045 is associated with emotional expression (2019)
  • Author(s): Shimanoe C, Hachiya T, Hara M, Nishida Y, Tanaka K, Sutoh Y, Shimizu A, Hishida A, Kawai S, Okada R, Tamura T, Matsuo K, Ito H, Ozaki E, Matsui D, Ibusuki R, Shimoshikiryo I, Takashima N, Kadota A, Arisawa K, Uemura H, Suzuki S, Watanabe M, Kuriki K, Endo
  • Journal Title: Genes Brain Behav Volume: 印刷中
  • DOI: 10.1111/gbb.12481
  • Peer Reviewed
• [Journal Article] Sleep duration and risk of breast cancer : The JACC Study. (2019)
  • Author(s): Cao J, Eshak ES, Liu K, Muraki I, Cui R, Iso H, Tamakoshi A
  • Journal Title: Breast Cancer Res Treat
  • DOI: 10.1007/s10549-018-4995-4
  • Peer Reviewed / Open Access
• [Journal Article] Self-Reported Eczema in Relation with Mortality from Cardiovascular Disease in Japanese : the Japan Collaborative Cohort Study. (2019)
  • Author(s): Nishida Y, Kubota Y, Iso H, Tamakoshi A
  • Journal Title: J Atheroscler Thromb Volume: 26 Issue: 9 Pages: 775-782
  • DOI: 10.5551/jat.46383
  • NAID: 130007699791
  • ISSN: 1340-3478, 1880-3873
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals (2019)
  • Author(s): Nakatochi M, Kanai M, Nakayama A, Hishida A, Kawamura Y, Ichihara S, Akiyama M, Ikezaki H, Furusyo N, Shimizu S, Yamamoto K, et al.
  • Journal Title: Communications Biology Volume: 2 Pages: 115-115
  • DOI: 10.1038/s42003-019-0339-0
  • Peer Reviewed / Open Access
• [Journal Article] Fat-soluble vitamins from diet in relation to risk of type 2 diabetes mellitus in Japanese population. (2019)
  • Author(s): Eshak ES, Iso H, Muraki I, Tamakoshi A.
  • Journal Title: Br J Nutr Pages: 1-18
  • Peer Reviewed / Open Access
• [Journal Article] Estimating genome-wide off-target effects for pyrrole-imoidazole polyamide binding by a pathway-based expression profiling approach (2019)
  • Author(s): J, Lin, S, Krishnamurthy, H. Yoda, Y. Shinozaki, T. Watanabe, N. Koshikawa, A. Takatori, P. Horton, H. Nagase
  • Journal Title: PLoS ONE Volume: 14 Pages: 4-4
  • DOI: 10.1371/journal.pone.0215247
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 髄液バイオマーカーとしての“脳型”トランスフェリン (2019)
  • Author(s): 村上友太、齋藤 清、高橋浩一、荒木信夫、橋本康弘
  • Journal Title: 自律神経
  • Peer Reviewed
• [Journal Article] Transferrin isoforms in cerebrospinal fluid and their relation to neurological diseases. (2019)
  • Author(s): Yuta Murakami, Kiyoshi Saito, Hiromi Ito, Yasuhiro Hashimoto
  • Journal Title: Proceedings of the Japan Academy, Series B
  • Peer Reviewed
• [Journal Article] Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein (2019)
  • Author(s): Aizawa H, Yamashita T, Kato H, Kimura T, Kwak S
  • Journal Title: J Clin Neurol Volume: 15（1） Issue: 1 Pages: 62-62
  • DOI: 10.3988/jcn.2019.15.1.62
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection. (2019)
  • Author(s): Takeuchi F, Kukimoto I, Li Z, Li S, Li N, Hu Z, Takahashi A, Inoue S, Yokoi S, Chen J, Hang D, Kuroda M, Matsuda F, Mizuno M, Mori S, Wu P, Tanaka N, Matsuo K, Kamatani Y, Kubo M, Ma D, Shi Y.
  • Journal Title: Hum Mol Genet Volume: 28 Pages: 341-348
  • DOI: 10.1093/hmg/ddy390
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Frequency of forest walking is not associated with prevalence of hypertension based on cross-sectional studies of a general Japanese population : A reconfirmation by the J-MICC Daiko Study (2019)
  • Author(s): Morita E, Kadomatsu Y, Tsukamoto M, Kubo Y, Okada R, Sasakabe T, Kawai S, Hishida A, Naito M, Wakai K.
  • Journal Title: Nagoya Journal of Medical Science
  • NAID: 120006716075
  • Description: in press
  • Peer Reviewed / Open Access
• [Journal Article] The association between urinary sodium excretion and blood pressure in a community-based population : the Yamagata (Takahata) study. (2019)
  • Author(s): Watanabe S, Konta T, Ichikawa K, Watanabe M, Ishizawa K, Ueno Y, Yamashita H, Kayama T, Kubota I.
  • Journal Title: Clinical and Experimental Nephrology Volume: 23 Pages: 380-386
  • DOI: 10.1007/s10157-018-1654-3
  • Peer Reviewed
• [Journal Article] Serum nardilysin, a surrogate marker for epithelial-mesenchymal transition, predicts prognosis of intrahepatic cholangiocarcinoma after surgical resection (2019)
  • Author(s): Yoh T, Hatano E, Kasai Y, Fujii H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, and Nishi E.
  • Journal Title: Clinical Cancer Research Volume: 25(2) Pages: 619-628
  • DOI: 10.1158/1078-0432.ccr-18-0124
  • Peer Reviewed / Open Access
• [Journal Article] Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report. (2019)
  • Author(s): Cook LB, Fuji S, Hermine O, Bazarbachi A, Ramos JC, Ratner L, Horwitz S, Fields P, Tanase A, Bumbea H, Cwynarski K, Taylor G, Waldmann TA, Bittencourt A, Marcais A, Suarez F, Sibon D, Phillips A, Lunning M, Farid R, Imaizumi Y, Choi I, Ishida T, Ishitsuka
  • Journal Title: J Clin Oncol. Volume: 37 Pages: 677-687
  • DOI: 10.1200/jco.18.00501
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] NPY deficiency prevents postmenopausal adiposity by augmenting estradiol-mediated browning. (2019)
  • Author(s): Park S, Nayantai E, Komatsu T, Hayashi H, Mori R, Shimokawa I
  • Journal Title: J Gerontol A Biol Sci Med Sci. Volume: -
  • DOI: 10.1093/gerona/gly282
  • Description: in press
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Identification of specific microRNAs in neutrophils of type 2 diabetic mice : overexpression of microRNA-129-2-3p accelerates diabetic wound healing. (2019)
  • Author(s): Umehara T, Mori R, Mace K, Murase T, Abe Y, Yamamoto T, Ikematsu K
  • Journal Title: Diabetes Volume: 68 Issue: 3 Pages: 617-630
  • DOI: 10.1124/jpet.118.253922
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Handling has an anxiolytic effect that is not affected by the inhibition of the protein kinase C pathway in adult prenatal undernourished male rat offspring. (2019)
  • Author(s): Hino K, Kimura T, Udagawa J
  • Journal Title: Congenit Anom Volume: 18 Issue: 2 Pages: 46-53
  • DOI: 10.1111/cga.12332
  • NAID: 210000155421
  • ISSN: 0914-3505, 1741-4520
  • Description: in press
  • Peer Reviewed
• [Journal Article] Ethanol Preference and Drinking Behavior Are Controlled by RNA Editing in the Nucleus Accumbens (2019)
  • Author(s): Takahira Shirahase, Yoshihisa Watanabe, Atsushi Tsujimura, Shin Kwak, Toshiro Yamamoto, Narisato Kanamura and Masaki Tanaka
  • Journal Title: Front. Behav. Neurosci Volume: 12 Pages: 1-12
  • DOI: 10.3389/fnbeh.2018.00331
  • Peer Reviewed / Open Access
• [Journal Article] Direct targeting of MYCN gene amplification by site-specific DNA alkylation in neuroblastoma (2019)
  • Author(s): H. Yoda, T. Inoue, Y. Shinozaki, J. Lin, T. Watanabe, N. Koshikawa, A. Takatori, H. Nagase
  • Journal Title: Cancer Research Volume: 79 Issue: 4 Pages: 830-840
  • DOI: 10.1158/0008-5472.can-18-1198
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Correlation of two distinct metastasis-associated proteins, MTA1 and S100A4, in angiogenesis for promoting tumor growth. (2019)
  • Author(s): Ishikawa M, Osaki M, Yamagishi M, Onuma K, Ito H, Okada F, Endo H
  • Journal Title: Oncogene Volume: in press
  • DOI: 10.1038/s41388-019-0748-z
  • Description: in press
  • Peer Reviewed / Open Access
• [Journal Article] Cell death cascade and molecular therapy in ADAR2-deficient motor neurons of ALS. (2019)
  • Author(s): Yamashita T, Kwak S
  • Journal Title: Neurosci Res Volume: 印刷中
  • DOI: 10.1016/j.neures.2018.06.004
  • Peer Reviewed
• [Journal Article] Associations of serum microRNA-20a, -27a, and -103a with cognitive function in a Japanese population : the Yakumo Study (2019)
  • Author(s): Kondo M, Yamada H, Munetsuna E, Yamazaki M, Hatta T, Iwahara A, Ohashi K, Ishikawa H, Tsuboi Y, Inoue T, Fujii R, Suzuki K
  • Journal Title: Archives of Gerontology and Geriatrics Volume: 82 Pages: 155-160
  • DOI: 10.1016/j.archger.2019.01.007
  • Peer Reviewed / Open Access
• [Journal Article] Association between soluble immune mediators and tumor responses in patients with nonsmall cell lung cancer treated with anti-PD-1 inhibitor. (2019)
  • Author(s): Matsuo N, Azuma K, Hattori S, Ohtake J, Kawahara A, Ishii H, Tokito T, Yamada K, Shibata Y, Shimokawaji T, Kondo T, Kato T, Saito H, Yamada K, Sasada T, Hoshino T.
  • Journal Title: Int J Cancer. Volume: 144 Issue: 5 Pages: 1170-1179
  • DOI: 10.1002/ijc.31923
  • Peer Reviewed / Open Access
• [Journal Article] APOE4-mediated amyloid-βpathology depends on its neuronal receptor LRP1 (2019)
  • Author(s): Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T.
  • Journal Title: J Clin Invest Volume: 129 Issue: 3 Pages: 1272-1277
  • DOI: 10.1172/jci124853
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Adult T-Cell Leukemia/Lymphoma-Related Ocular Manifestations : Analysis of the First Large-Scale Nationwide Survey. (2019)
  • Author(s): Kamoi K, Okayama A, Izumo S, Hamaguchi I, Uchimaru K, Tojo A, Ohno-Matsui K.
  • Journal Title: Front Microbiol. Volume: 9 Pages: 3240-3240
  • DOI: 10.3389/fmicb.2018.03240
  • Peer Reviewed / Open Access
• [Journal Article] ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs (2019)
  • Author(s): Hosaka T, Yamashita T, Teramoto S, Hirose N, Tamaoka A, Kwak S
  • Journal Title: Neurosci Res Volume: 印刷中
  • DOI: 10.1016/j.neures.2018.11.005
  • Peer Reviewed
• [Journal Article] 5-HT3 Antagonist Ondansetron Increases ApoE Secretion by Modulating the LXR-ABCA1 Pathway (2019)
  • Author(s): Shinohara M, Shinohara M, Zhao J, Fu Y, Liu C C, Kanekiyo T, Bu G.
  • Journal Title: Int. J. Mol. Sci Volume: 20 Issue: 6 Pages: 1488-1488
  • DOI: 10.3390/ijms20061488
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Correlation between thyroid stimulating hormone and the renal function of cuthyroid residents of Japan : Results from the Kyushu and Okinawa Population Study(KOPS) (2018)
  • Author(s): Tanaka Y, Furusyo N, Kato Y, Ueyama T, Yamasaki S, Murata M, Hayashi J.
  • Journal Title: J Atheroscler Thromb Volume: 25 Issue: 4 Pages: 335-343
  • DOI: 10.5551/jat.41251
  • NAID: 130006602295
  • ISSN: 1340-3478, 1880-3873
  • Year and Date: 2018-04-01
  • Peer Reviewed
• [Journal Article] Autologous peripheral blood stem cell transplantation for double-refractory myeloma with <i>K-RAS</i> and <i>N-RAS</i> mutations (2018)
  • Author(s): 神保光児、横山和明、小川弥穂、平野光人、越智清純、小林真之、遊佐 希、清水英悟、川俣豊隆、大野伸広、山口 類、井元清哉、古川洋一、宮野 悟、今井陽一、東條有伸.
  • Journal Title: Jpn. J. Clin. Hematol. Volume: 58 Issue: 12 Pages: 2380-2385
  • DOI: 10.11406/rinketsu.58.2380
  • NAID: 130006308839
  • ISSN: 0485-1439, 1882-0824
  • Year and Date: 2018-01-13
  • Peer Reviewed / Open Access
• [Journal Article] Heterogeneous impact of smoking on major salivary gland cancer according to histopathological subtype : A case-control study. (2018)
  • Author(s): Sawabe M, Ito H, Takahara T, Oze I, Kawakita D, Yatabe Y, Hasegawa Y, Murakami S, Matsuo K.
  • Journal Title: Cancer Volume: 124 Issue: 1 Pages: 118-124
  • DOI: 10.1002/cncr.30957
  • Peer Reviewed / Open Access
• [Journal Article] Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. (2018)
  • Author(s): Ghoussaini M, Edwards SL, Matsuo K, Dunning AM, et al.
  • Journal Title: Nat Commun Volume: 9 Pages: 16193-16193
  • DOI: 10.1038/ncomms16193
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. (2018)
  • Author(s): Earp M, Tyrer JP, Matsuo K, Goode EL, Phelan CM, et al.
  • Journal Title: PLoS ONE Volume: 13 Issue: 7
  • DOI: 10.1371/journal.pone.0197561
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer : a replication and mediation analysis. (2018)
  • Author(s): Ishioka K, Masaoka H, Ito H, Oze I, Ito S, Tajika M, Shimizu Y, Niwa Y, Nakamura S, Matsuo K.
  • Journal Title: Gastric Cancer Volume: 印刷中 Issue: 6 Pages: 936-945
  • DOI: 10.1007/s10120-018-0823-0
  • NAID: 40021694566
  • Peer Reviewed / Open Access
• [Journal Article] Value assignment of the reference material for human T-cell leukemia virus type l quantitative PCR in Japan (2018)
  • Author(s): Madoka Kuramitsu, Kaoru Uchimaru, Yasuko Sagara, Toshiki Watanabe, Isao Hamaguchi, et al.
  • Journal Title: Microbiol Immunol Volume: 62 Issue: 10 Pages: 673-676
  • DOI: 10.1111/1348-0421.12644
  • NAID: 40021702629
  • Peer Reviewed / Open Access
• [Journal Article] The association between self-rated health and high-sensitivity C-reactive protein level : a cross-sectional and 5-year longitudinal study. (2018)
  • Author(s): Tamura T, Naito M, Maruyama K, Tsukamoto M, Sasakabe T, Okada R, Kawai S, Hishida A, Wakai K.
  • Journal Title: BMC Public Health Volume: 18 Issue: 1 Pages: 1380-1380
  • DOI: 10.1186/s12889-018-6251-6
  • Peer Reviewed / Open Access
• [Journal Article] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD. (2018)
  • Author(s): Endo, R., Takashima, N., Nekooki-Machida, Y., Komi, Y., Hui, K. K., Takao, M., Akatsu, H., Murayama, S., Sawa, A., and Tanaka, M.
  • Journal Title: Biol. Psychiatry Volume: 84(7) Pages: 509-521
  • DOI: 10.1016/j.biopsych.2018.03.008
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Potential anti-lymphoma effect of M-CSFR inhibitor in adult T-cell leukemia/lymphoma (2018)
  • Author(s): Yoshihiro Komohara, Osamu Noyori, Yoichi Saito, Hiroto Takeya, Muhammad Baghdadi, Fumihito Kitagawa, Naoki Hama, Kozo Ishikawa, Yutaka Okuno, Kisato Nosaka, Ken-ichiro Seino, Masao Matsuoka, Shinya Suzu
  • Journal Title: J Clin Exp Hematopathol Volume: Vol. 58 No.4 Issue: 4 Pages: 152-160
  • DOI: 10.3960/jslrt.18034
  • NAID: 130007529824
  • ISSN: 1346-4280, 1880-9952
  • Peer Reviewed / Open Access
• [Journal Article] Methylation changes and aberrant expression of FGFR3 in Lewy body disease neurons (2018)
  • Author(s): Takeyuki Tsuchida, Tatsuo Mano, Kagari-Koshi-Mano, Taro Bannai, Satoshi Yamashita, Toshikazu Ushijima, Kenichi Nagata, Shigeo Murayama, Tatsushi Toda, Shoji Tsuji, Atsushi Iwata
  • Journal Title: Brain Research Volume: 1697 Pages: 59-66
  • DOI: 10.1016/j.brainres.2018.06.017
  • Peer Reviewed
• [Journal Article] Inverse association between soy food consumption, especially fermented soy products intake and soy isoflavone, and arterial stiffness in Japanese men (2018)
  • Author(s): Hirokazu Uemura, Sakurako Katsuura-Kamano, Mariko Nakamoto, Miwa Yamaguchi, Miho Fujioka, Yuki Iwasaki, Kokichi Arisawa
  • Journal Title: Scientific Reports Volume: 8 Issue: 1 Pages: 9667-9667
  • DOI: 10.1038/s41598-018-28038-0
  • NAID: 120006535059
  • Peer Reviewed / Open Access
• [Journal Article] Interleukin-34, a comprehensive review (2018)
  • Author(s): Muhammad Baghdadi, Yui Umeyama, Naoki Bama, Takuto Kobayashi, Nanumi Han, Haruka Wada, Ken-ichiro Seino
  • Journal Title: Journal of leukocyte biology Volume: 104 Issue: 5 Pages: 931-951
  • DOI: 10.1002/jlb.mr1117-457r
  • Peer Reviewed / Open Access
• [Journal Article] High co-expression of IL-34 and M-CSF correlates with tumor progression and poor survival in lung cancers (2018)
  • Author(s): Baghdadi M, Endo H, Takano A, Ishikawa K, Kameda Y, Wada H, Miyagi Y, Yokose T, Ito H, Nakayama H, Daigo Y, Suzuki N, Seino K
  • Journal Title: Sci Rep. Volume: 11;8(1) Issue: 1 Pages: 418-418
  • DOI: 10.1038/s41598-017-18796-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genome-Wide Association Study to Identify a New Susceptibility Locus for Central Serous Chorioretinopathy in the Japanese Population. (2018)
  • Author(s): MikiA, SakuradaY, TanakaK, SembaK, MitamuraY, YuzawaM, TajimaA, NakatochiM, YamamotoK, MatsuoK, ImotoI, HondaS.
  • Journal Title: Invest Ophtalmol Vis Sci Volume: 59(13) Issue: 13 Pages: 5542-5542
  • DOI: 10.1167/iovs.18-25497
  • NAID: 120006550257
  • Peer Reviewed / Open Access
• [Journal Article] Genome-Wide Association Study of Renal Function Traits : Results from the Japan Multi-Institutional Collaborative Cohort Study. (2018)
  • Author(s): Hishida A, Nakatochi M, Akiyama M, Kamatani Y, Nishiyama T, Ito H, Oze I, Nishida Y, Hara M, Takashima N, Turin TC, Watanabe M, Suzuki S, Ibusuki R, Shimoshikiryo I, Nakamura Y, Mikami H, Ikezaki H, Furusyo N, Kuriki K, Endoh K, Koyama T, Matsui D, Uemura
  • Journal Title: American Journal of Nephrol Volume: 47 Issue: 5 Pages: 304-316
  • DOI: 10.1159/000488946
  • NAID: 120006504382
  • Peer Reviewed
• [Journal Article] Genomewide Association Study of Leisure-Time Exercise Behavior in Japanese Adults. (2018)
  • Author(s): Hara M, Hachiya T, Sutoh Y, Matsuo K, Nishida Y, Shimanoe C, Tanaka K, Shimizu A, Ohnaka K, Kawaguchi T, Oze I, Matsuda F, Ito H, Kawai S, Hishida A, Okada R, Sasakabe T, Hirata A, Ibusuki R, Nindita Y, Furusyo N, Ikezaki H, Kuriyama N, Ozaki E, Mikami H.
  • Journal Title: Med Sci Sports Exerc Volume: 50 Issue: 12 Pages: 2433-2441
  • DOI: 10.1249/mss.0000000000001712
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide association study for pollinosis identified two novel loci in interleukin (IL)-IB in a Japanese population. (2018)
  • Author(s): Fujii R, Hishida A, Wu MC. Kondo T, Hattori Y, Naito M, Endoh K, Nakatochi M, Hamajima N, Kubo M, Kuriki K, Wakai K.
  • Journal Title: Nagoya Journal of Medical Science Volume: 80 Issue: 1 Pages: 109-120
  • NAID: 120006410517
  • URL: http://hdl.handle.net/2237/00027495
  • Peer Reviewed / Open Access
• [Journal Article] Enhanced IL-34 expression in Nivolumab-resistant metastatic melanoma (2018)
  • Author(s): Nanumi Han, Muhammad Baghdadi, Kozo Ishikawa, Hiraku Endo, Takuto Kobayashi, Haruka Wada, Keisuke Imafuku, Hiroo Hata, Ken-ichiro Seino
  • Journal Title: Inflammation and Regeneration Volume: 5 Pages: 3-3
  • DOI: 10.1186/s41232-018-0060-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Enhanced expression of IL-34 in an inflammatory cyst of the submandibular gland : a case report (2018)
  • Author(s): Muhammad Baghdadi, Kozo Ishikawa, Hiraku Endo, Yui Umeyama, Tsukasa Ataka, Haruka Wada, Yumiko Oyamada, Naoki Hyakushima, Ken-ichiro Seino
  • Journal Title: Inflammation and Regeneration Volume: 38 Issue: 12
  • DOI: 10.1186/s41232-018-0069-6
  • Peer Reviewed / Open Access
• [Journal Article] Effects of the -141C insertion/deletion polymorphism in the dopamine D2 receptor gene on the dopamine system in the striatum in patients with schizophrenia (2018)
  • Author(s): Matsumoto J, Nagaoka A, Kunii Y, Miura I, Hino M, Niwa SI, Nawa H, Takahashi H, Kakita A, Yabe H
  • Journal Title: Psychiatry Res Volume: 264 Pages: 116-118
  • DOI: 10.1016/j.psychres.2018.03.029
  • Peer Reviewed
• [Journal Article] Dietary Antioxidant Micronutrients and All-Cause Mortality : The Japan Collaborative Cohort Study for Evaluation of Cancer Risk. (2018)
  • Author(s): Ma E, Iso H, Yamagishi K, Ando M, Wakai K, Tamakoshi A.
  • Journal Title: Journal of Epidemiology Volume: 28 Issue: 9 Pages: 388-396
  • DOI: 10.2188/jea.je20170023 10.2188/jea.JE20170023
  • NAID: 130006745191
  • ISSN: 0917-5040, 1349-9092
  • Peer Reviewed / Open Access
• [Journal Article] Common variant of BCAS3 is associated with gout risk in Japanese population : the first replication study after gout GWAS in Han Chinese. (2018)
  • Author(s): Sakiyama M, Matsuo H, Nakaoka H, Kawamura Y, Kawaguchi M, Higashino T, Nakayama A, Akashi A, Ueyama J, Kondo T, Wakai K, Sakurai Y, Yamamoto K, Ooyama H, Shinomiya N.
  • Journal Title: BMC Med Genet Volume: 19 Issue: 1 Pages: 96-96
  • DOI: 10.1186/s12881-018-0583-z
  • Peer Reviewed / Open Access
• [Journal Article] Cardiovascular disease mortality in relation to physical activity during adolescence and adulthood in Japan : Does school-based sport club participation matter? (2018)
  • Author(s): Gero K, Iso H, Kitamura A, Yamagishi K, Yatsuya H, Tamakoshi A.
  • Journal Title: Prev Med Volume: 113 Pages: 102-108
  • DOI: 10.1016/j.ypmed.2018.05.012
  • NAID: 120006492211
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association of exposure level to passive smoking with hypertension among lifetime nonsmokers in Japan : a cross-sectional study. (2018)
  • Author(s): Tamura T, Kadomatsu Y, Tsukamoto M, Okada R, Sasakabe T, Kawai S, Hishida A, Hara M, Tanaka K, Shimoshikiryo I, Takezaki T, Watanabe I, Matsui D, Nishiyama T, Suzuki S, Endoh K, Kuriki K, Kita Y, Katsuura-Kamano S, Arisawa K, Ikezaki H, Furusyo N, Koyanag
  • Journal Title: Medicine (Baltimore) Volume: 97 Issue: 48
  • DOI: 10.1097/md.0000000000013241
  • Peer Reviewed / Open Access
• [Journal Article] A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption : The J-MICC Study (2018)
  • Author(s): Nakagawa-Senda H, Hachiya T, Shimizu A, Hosono S, Oze I, Watanabe M, Matsuo K, Ito H, Hara M, Nishida Y, Endoh K, Kuriki K, Katsuura-Kamano S, Arisawa K, Nindita Y, Ibusuki R, Suzuki S, Hosono A, Mikami H, Nakamura Y, Takashima N, Nakamura Y, Kuriyama N.
  • Journal Title: Sci Rep Volume: 8 Issue: 1 Pages: 1493-1493
  • DOI: 10.1038/s41598-018-19914-w
  • NAID: 120006535054
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• [Journal Article] Water intake from foods and beverages and risk of mortality from CVD : the Japan Collaborative Cohort (JACC) Study. (2018)
  • Author(s): Cui R, Iso H, Eshak ES, Maruyama K, Tamakoshi A
  • Journal Title: Public Health Nutr Volume: 21 Issue: 16 Pages: 3011-3017
  • DOI: 10.1017/s1368980018001386
  • Peer Reviewed / Open Access
• [Journal Article] Multiancestry genome-wide association study of 520.000 subjects identifies 32 loci associated with stroke and stroke subtypes. (2018)
  • Author(s): Malik R, Chauhan G, Wakai K, Weir D, Williams SR, Wolfe CDA, Wong Q, Xu H, Yamaji T, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worral
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Ikigai, Subjective Wellbeing, as a Modifier of the Parity-Cardiovascular Mortality Association- The Japan Collaborative Cohort Study. (2018)
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  • Peer Reviewed
• [Journal Article] Genome-wide association study identifies gastric cancer susceptibility loci at 12q24. 11-12 and 20q11. 21 (2018)
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  • Journal Title: Cancer Science Volume: 109 Issue: 12 Pages: 4015-4024
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• [Journal Article] Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13. 1. (2018)
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• [Journal Article] Fish Intake and Death From Pulmonary Embolisms Among Japanese Men and Women- The Japan Collaborative Cohort (JACC) Study. (2018)
  • Author(s): Ohira T, Iso H, Yamagishi K, Tamakoshi A
  • Journal Title: Circ J Volume: 82 Issue: 8 Pages: 2063-2070
  • DOI: 10.1253/circj.cj-18-0040 10.1253/circj.CJ-18-0040
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  • Peer Reviewed / Open Access
• [Journal Article] 脳脊髄液減少症(特発性低髄液圧症候群)と脳型トランスフェリン (2018)
  • Author(s): 村上友太、高橋浩一、星 京香、伊藤浩美、齋藤 清、宮嶋雅一、新井 一、美馬達夫、橋本康弘
  • Journal Title: 日本頭痛学会誌 Volume: 45 Issue: 1 Pages: 25-33
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• [Journal Article] Novel Common Genetic Susceptibility Loci for Colorectal Cancer. (2018)
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• [Journal Article] Spontaneous intracranial hypotension is diagnosed by a combination of lipocalin-type prostaglandin D synthase and brain-type transferrin in cerebrospinal fluid (2018)
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  • Journal Title: BBA General Subjects Volume: 1862 Pages: 1835-1842
  • DOI: 10.1016/j.bbagen.2018.03.027
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• [Journal Article] Rapid increase of "brain-type" transferrin in cerebrospinal fluid after shunt surgery for idiopathic normal pressure hydrocephalus : a prognosis marker for cognitive recovery (2018)
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  • Journal Title: J Biochem Volume: 164 Issue: 3 Pages: 205-213
  • DOI: 10.1093/jb/mvy043
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• [Journal Article] Quantitative Analysis of Surface Electromyography for Pediatric Neuromuscular Disordersの研究 (2018)
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  • Journal Title: Muscle Nerve Volume: 58 Issue: 6 Pages: 824-827
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• [Journal Article] Prediction model for pancreatic cancer risk in the general Japanese population. (2018)
  • Author(s): Nakatochi M, Lin Y, Ito H, Hara K, Kinoshita F, Kobayashi Y, Ishii H, Ozaka M, Sasaki T, Sasahira N, Morimoto M, Kobayashi S, Ueno M, Ohkawa S, Egawa N, Kuruma S, Mori M, Nakao H, Wang C, Nishiyama T, Kawaguchi T, Takahashi M, Matsuda F, Kikuchi S, Matsuo
  • Journal Title: PloS ONE Volume: 13(9)
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• [Journal Article] Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia (2018)
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  • Journal Title: Psychiatry Res Volume: 270 Pages: 940-946
  • DOI: 10.1016/j.psychres.2018.10.062
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• [Journal Article] p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adpocytes and cancer cells. (2018)
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  • Journal Title: Neoplasia Volume: 9 Issue: 9 Pages: 883-893
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  • Author(s): Hiromi Ito, Kyoka Hoshi, Takashi Honda, Yasuhiro Hashimoto
  • Journal Title: Molecule Volume: 23 Pages: 1314-1314
  • DOI: 10.3390/molecules23061314
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• [Journal Article] Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. (2018)
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  • Journal Title: Gastroenterology
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• [Journal Article] Interethnic analyses of blood pressure loci in populations of East Asian and European descent. (2018)
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  • Journal Title: Nature Communications Volume: 9 Pages: 5052-5052
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  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 72 Issue: 4 Pages: 280-294
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• [Journal Article] Fish intake and risk of mortality due to aortic dissection and aneurysm : A pooled analysis of the Japan cohort consortium (2018)
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• [Journal Article] Cigarette smoking and cervical cancer risk : an evaluation based on a systematic review and meta-analysis among Japanese women (2018)
  • Author(s): Sugawara Y, Tsuji I, Mizoue T, Inoue M, Sawada N, Matsuo K, Ito H, Naito M, Nagata C, Kitamura Y, Sadakane A, Tanaka K, Tamakoshi A, Tsugane S, Shimazu T ; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.
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• [Journal Article] CD30 Characterizes Polylobated Lymphocytes and Disease Progression in HTLV-1-Infected Individuals. (2018)
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  • Journal Title: Clin Cancer Res. Volume: 24 Issue: 21 Pages: 5445-5457
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  • Journal Title: Cell Volume: 174(3) Issue: 3 Pages: 636-648
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• [Journal Article] Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling. (2018)
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  • Journal Title: Biol Cell Volume: 110 Issue: 5 Pages: 109-124
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• [Journal Article] Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds. (2018)
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  • Journal Title: EMBO Mol Med Volume: 2018 Issue: 10 Pages: 1-21
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• [Journal Article] Study on the tumor-induced angiogenesis using mathematical models. (2018)
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  • Journal Title: Cancer Science Volume: 109 Pages: 15-23
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• [Journal Article] Somatic mutations in the human brain : implications for psychiatric research (2018)
  • Author(s): Masaki Nishioka, Miki Bundo, Kazuya Iwamoto, Tadafumi Kato
  • Journal Title: Molecular Psychiatry Volume: -
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  • Description: ePub Published : 07 August 2018
  • Peer Reviewed / Open Access
• [Journal Article] Relationship between Long Interspersed Nuclear Element-1 DNA Methylation in Leukocytes and Dyslipidemia in the Japanese General Population. (2018)
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  • Journal Title: J Atheroscler Thromb Volume: 25 Issue: 12 Pages: 1231-1239
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• [Journal Article] Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease : The Japan Collaborative Cohort Study. (2018)
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  • Journal Title: Stroke Volume: 49 Issue: 2 Pages: 454-457
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• [Journal Article] Reduced gray matter volume is correlated with frontal cognitive and behavioral impairments in Parkinson's disease (2018)
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• [Journal Article] Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma. (2018)
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  • Journal Title: Biomark Res Volume: 6 Pages: 24-24
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  • Journal Title: Acta Neuropathol Commun. Volume: 6 Pages: 53-53
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• [Journal Article] Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation. (2018)
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  • Journal Title: JCI insight Volume: 3 Issue: 8 Pages: 1-15
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• [Journal Article] Maternal undernutrition during early pregnancy inhibits postnatal growth of the tibia in the female offspring of rats by alteration of chondrogenesis. (2018)
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  • Journal Title: Gen Comp Endocrinol. Volume: 260 Issue: 1 Pages: 58-60
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• [Journal Article] Identification of proteolytic cleavage sites of EphA2 by membrane type-1 matrix metalloproteinase on the surface of cancer cells (2018)
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  • Journal Title: Methods in Molecular Biology Volume: 1731 Pages: 29-37
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• [Journal Article] Identification of a novel HLA-A24-restricted cytotoxic T lymphocyte epitope peptide derived from mesothelin in pancreatic cancer. (2018)
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  • Journal Title: Oncotarget Volume: 9 Issue: 59 Pages: 31448-31458
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• [Journal Article] Identification and functional analysis of inflammation-related miRNAs in skin wound repair. (2018)
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  • Journal Title: Dev Growth Differ Volume: 60 Issue: 6 Pages: 306-315
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• [Journal Article] HIV LTR-driven antisense RNA by itself has regulatory function and may curtail virus reactivation from latency. (2018)
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  • Journal Title: Front. Microbiol. Volume: 9 Pages: 1066-1066
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• [Journal Article] Glucagonoma With Necrolytic Migratory Erythema : Metabolic Profile and Detection of Biallelic Inactivation of DAXX Gene. (2018)
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  • Journal Title: J Clin Endocrinol Metab Volume: 23 Issue: 7 Pages: 2417-2423
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• [Journal Article] Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent. (2018)
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  • Journal Title: Wellcome Open Res. Volume: 3
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• [Journal Article] Enhanced expression of PD-L1 in non-muscle-invasive bladder cancer after treatment with Bacillus Calmette-Guerin. (2018)
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  • Journal Title: Oncotarget. Volume: 9 Issue: 75 Pages: 34066-34078
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• [Journal Article] Dietary intakes of fat soluble vitamins as predictors of mortality from heart failure in a large prospective cohort study. (2018)
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  • Journal Title: Nutrition Volume: 47 Pages: 50-55
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• [Journal Article] Chronic inflammatory demyelinating polyneuropathy in adult T-cell leukemia-lymphoma patients following allogeneic stem cell transplantation. (2018)
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• [Journal Article] Associations between dietary intakes of iron, copper and zinc with risk of type 2 diabetes mellitus : A large population-based prospective cohort study. (2018)
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  • Journal Title: Clin Nutr Volume: 印刷中 Issue: 2 Pages: 667-674
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• [Journal Article] Associations between copper and zinc intakes from diet and mortality from cardiovascular disease in a large population-based prospective cohort study. (2018)
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  • Journal Title: J Nutr Biochem Volume: 56 Pages: 126-132
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• [Journal Article] Association of subcutaneous and visceral fat with circulating microRNAs in a middle-aged Japanese population. (2018)
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  • Journal Title: Annals of Clinical Biochemistry Volume: 55 Issue: 4 Pages: 437-445
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• [Journal Article] Association of Decreased Handgrip Strength with Reduced Cortical Thickness in Japanese Female Patients with Type 2 Diabetes Mellitus. (2018)
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• [Journal Article] Activated EphA2 processing by MT1-MMP is involved in malignant transformation of ovarian tumours in vivo (2018)
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  • Journal Title: Anticancer Res Volume: 38 Pages: 4257-4266
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• [Journal Article] A Potential New Risk Factor for Stroke : Streptococcus Mutans With Collagen-Binding Protein. (2018)
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• [Journal Article] Complete Sequences of the HTLV-1 Proviral Genomes from Newly Established ATL cell-lines in Oita Prefecture, Japan (2018)
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  • Journal Title: Genome Announcements Volume: 6 Issue: 25
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  • Peer Reviewed / Open Access
• [Journal Article] 成人T細胞白血病・リンパ腫のエピゲノム異常と新規EZH1/2阻害剤の開発 (2018)
  • Author(s): 山岸誠
  • Journal Title: 臨床血液 Volume: 59 Pages: 432-438
• [Journal Article] HTLV-1感染細胞におけるゲノム・エピゲノム異常 (2018)
  • Author(s): 山岸誠
  • Journal Title: 医学の歩み Volume: 267 Pages: 771-775
• [Journal Article] 悪性リンパ腫におけるEZH1/EZH2依存性エピゲノム異常と創薬 (2018)
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• [Journal Article] Modification of the associations of alcohol intake with serum low-density lipoprotein cholesterol and triglycerides by ALDH2 and ADHIB polymorphisms in Japanese men (2018)
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  • Journal Title: Journal of Epidemiology Volume: 28 Issue: 4 Pages: 185-193
  • DOI: 10.2188/jea.je20160189 10.2188/jea.JE20160189
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  • Description: in press
  • Peer Reviewed / Open Access
• [Journal Article] Association of genetic polymorphisms with erythrocyte traits : Verification of SNPs reported in a previous GWAS in a Japanese population (2018)
  • Author(s): Seiki T, Naito M, Hishida A, Takagi S, Matsunaga T, Sasakabe T, Hattori Y, Kawai S, Okada R, Yin G, Hamajima N, Wakai K.
  • Journal Title: Gene Volume: 642 Pages: 172-177
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• [Journal Article] Genome-wide association study identifies seven novel susceptibility loei for primary open-angle glaucoma (2018)
  • Author(s): Shiga Y, Akiyama M, Nishiguchi K M, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, Wakai K, Yoshikawa M, Miyake M, Yanaka T, et al.
  • Journal Title: Human Molecular Genetics Volume: 27 Issue: 8 Pages: 1458-1467
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  • Journal Title: Carcinogenesis Volume: Epub Pages: 652-660
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• [Journal Article] A Common variant of MAF/c-MAF, transcriptional factor genc in the kidney, is associated with gout susceptjbility. (2018)
  • Author(s): Toshihide Higashino, Hirotaka Matsuo, Yukinori Okada, Hiroshi Nakashima, Seiko Shimizu, Masayuki Sakiyama, Shin Tadokoro, Akiyoshi Nakayama, Makoto Kawaguchi, Mako Komatsu, Asahi Hishida, Masahiro Nakatochi, Hiroshi Ooyama, Junko Imaki, Nariyoshi Shinomiy
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• [Journal Article] Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Hcart Disease : The Japan Collaborative Cohort Study (2018)
  • Author(s): Sheerah HA, Eshak ES, Cui R, Imano H, Iso H, Tamakoshi A.
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• [Journal Article] The prospective association between plasma concentrations of cellular growth factors and risk of heart failure mortality in Japanese population. (2018)
  • Author(s): Ehab S Eshak, Koutatsu Maruyama, Hiroyasu Iso, Akiko Tamakoshi.
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• [Journal Article] Physical activity earlier in life is inversely associated with insulin resistance among adults in Japan (2018)
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  • Author(s): 藤田ひとみ、鈴木貞夫
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  • Author(s): Kamiya M. Hosono A. Tamai Y. Watanabe M. Shibata K. Tsujimura S. Oka K. Fujita H. Okamoto X. Kondo F. Wakabayashi R, Yamada T. Suzuki S.
  • Journal Title: Nagoya Medical Journal
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  • Journal Title: Neuropathology Volume: 38 Issue: 2 Pages: 171-178
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  • Journal Title: Neuropathology Volume: 12 Pages: 300-304
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  • Journal Title: Int J Oncol Volume: 52(1) Pages: 155-165
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• [Journal Article] The effect of forced expression of mutated K-RAS gene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy. (2017)
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• [Journal Article] Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer. (2017)
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  • Journal Title: Oncotarget Volume: 6(28) Issue: 29 Pages: 10448-10458
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  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma. (2017)
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  • Journal Title: Sci Rep Volume: 7 Pages: 45768-45768
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• [Journal Article] Inhibition of PRDM14 expression in pancrcatic cancer suppresses cancer stem-like properties and liver mctastasis in mice. (2017)
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• [Journal Article] 日本の疾患コホートとしてのバイオバンクジャパンの取組 (2017)
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• [Journal Article] Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes : a cross-sectional study in postmenopausal Japanese women (2017)
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• [Journal Article] Higher dietary cholesterol and omega-3 fatty acid intakes aro assoejatod with a lower succossful rate of Helicobacter pylori oradication therapy in Japan. (2017)
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• [Journal Article] Accuracy of self-reported height, weight and waist circumference in a Japanese sample (2017)
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  • Journal Title: PLoS One Volume: 12 Issue: 2
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• [Journal Article] Beta-N-methylamino-l-alanine analysis in the brains of patients with Kii ALS/PDC. (2017)
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• [Journal Article] Beyond the midbrain atrophy : wide spectrum of structural MRI finding in cases of pathologically proven progressive supranuclear palsy. (2017)
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• [Journal Article] Expression of secreted phosphoprotein 1 (osteopontin) in human sensorimotor cortex and spinal cord : Changes in patients with amyotrophic lateral sclerosis. (2017)
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• [Journal Article] Technical feasibility of visualizing myenteric plexus using confocal lasor endomicroscopy. (2017)
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• [Journal Article] Carbohydrate antigen 19-9- positive gastric adenocarcinoma : autopsy findings and review of the literature. Case Rep Gastroenterol. 11 3 545-553 2017 (2017)
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  • Journal Title: Case Reports in Gastroenterology Volume: 11 Pages: 545-553
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• [Journal Article] Pathologic study of intracranial large artery atherosclerosis in 7260 autopsy cases. (2017)
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  • Journal Title: J Stroke Cerebrovasc Dis. Volume: 26 Issue: 12 Pages: 2821-2827
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• [Journal Article] Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease. (2017)
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• [Journal Article] Reduccd LRRK2 in association with retromer dysfunction in postmortem brain tissue from LRRK2 mutation carriers. (2017)
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  • Journal Title: 検査と技術 Volume: 45 Issue: 11 Pages: 1286-1290
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• [Journal Article] Autopsy case of C12orf65 mutation in a patient with signs of mitochondrial dysfunction. (2017)
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• [Journal Article] 脳病理からみた超高齢者 (2017)
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• [Journal Article] 神経核内封入体病(NIID)の頭部MRI経時的変化 (2017)
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• [Journal Article] 大脳皮質基底核変性症の1剖検例 (2017)
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• [Journal Article] 臨床医のための神経病理 再入門 アストログリアの病理 (2017)
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  • Journal Title: Clinical Neuroscience Volume: 35 Issue: 10 Pages: 1152-1153
• [Journal Article] 嗜銀顆粒性認知症 (2017)
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• [Journal Article] Lysophosphatidylcholine export by human ABCA7. (2017)
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  • Journal Title: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Volume: 印刷中 Issue: 7 Pages: 658-665
  • DOI: 10.1016/j.bbalip.2017.03.012
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia (2017)
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• [Journal Article] Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer's disease (2017)
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• [Journal Article] A novel diagnostic marker for Alzheimer's disease (2017)
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• [Journal Article] ヒト, マウス組織におけるABCA1, ABCA7蛋白の作用機構の解析 (2017)
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  • Journal Title: 臨床病理 Volume: 65 Pages: 183-183
• [Journal Article] LC-MS/MSを用いたヒト脳脊髄液中におけるアルツハイマー病の新規バイオマーカー探索 (2017)
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• [Journal Article] LC-HR/MSによるアルツハイマー病患者脳脊髄液のキラルメタボロミクス (2017)
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• [Journal Article] 高精度キラルメタボロミクスの開発とアルツハイマー患者分析への応用 (2017)
  • Author(s): 高山卓大、水野初、豊岡利正、井之上浩一、赤津裕康、轟木堅一郎
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  • Journal Title: Neuron Volume: 94 Issue: 6 Pages: 1085-1100
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• [Journal Article] Thyroid transcription factor-1-regulated miR-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells (2017)
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  • Journal Title: Cancer Science Volume: 108 Issue: 7 Pages: 1394-1404
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• [Journal Article] Epidemiological and clinical features of adult T-cell leukemia-lymphoma (ATL) in Japan, 2010-2011 : a nationwide survey (2017)
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• [Journal Article] Evaluation of the sensitivity and specificity performance of the Elecsys® HTLV-I/II assay in a multicenter study in Europe and Japan (2017)
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• [Journal Article] GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes (2017)
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• [Journal Article] Comparison of weighed food record procedures for the reference methods in two validation studies of food frequency questionnaires. (2017)
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  • Peer Reviewed / Open Access
• [Journal Article] Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree (2017)
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• [Journal Article] Interactions between Inflammatory Gene Polymorphisms and HTLV-I Infection for Total Death, Incidence of Cancer, and Atherosclerosis-Related Diseases among the Japanese Population. (2017)
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  • Description: in press
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• [Journal Article] No modifying effect of education level on the association between lifestyle behaviors and cardiovascular mortality : the Japan Collaborative Cohort Study (2017)
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• [Journal Article] Perceived Stress and Colorectal Cancer Incidence : The Japan Collaborative Cohort Study (2017)
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  • Peer Reviewed
• [Journal Article] Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm (2017)
  • Author(s): Suzuki K, Suzuki Y, Hama A, Muramatsu H, Nakatochi M, Gunji M, Ichikawa D, Hamada M, Taniguchi R, Kataoka S, Murakami N, Kojima D, Sekiya Y, Nishikawa E, Kawashima N, Narita A, Nishio N, Nakazawa Y, Iwafuchi H, Watanabe K., et. al
  • Journal Title: Leukemia
  • DOI: 10.1038/leu.2017.101
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations. (2017)
  • Author(s): Seow WJ, Matsuo K, Shiraishi K, Kubo M, Daigo Y, Ito H, Sakamoto H, Kunitoh H, Tsuta K, Miyagi Y, Nakayama H, Matsumoto S, Tsuboi M, Goto K, Takahashi A, Goto A, Minamiya Y, Shimizu K, Tanaka K, Kohno T, et al.
  • Journal Title: Hum Mol Genet Volume: 26(2) Pages: 454-465
  • DOI: 10.1093/hmg/ddw414
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Adult T-cell leukemia (ATL) : molecular basis for clonal expansion and transformation of HTLV-1-infected T cells (2017)
  • Author(s): Watanabe T
  • Journal Title: Blood Volume: 129 Pages: 1071-1081
  • DOI: 10.1182/blood-2016-09-692574
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Cancer stem cells in human gastrointestinal cancer. (2016)
  • Author(s): Taniguchi H, Moriya C, Igarashi H, Saitoh A, Yamamoto H, Adachi Y, Imai K.
  • Journal Title: Cancer Sci Volume: 107 Issue: 11 Pages: 1556-1562
  • DOI: 10.1111/cas.13069
  • Peer Reviewed / Open Access
• [Journal Article] A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer. (2016)
  • Author(s): Kumegawa K, Maruyama R, Yamamoto E, Ashida M, Kitajima H, Tsuyada A, Niinuma T, Kai M, Yamano H, Sugai T, Tokino T, Shinomura Y, Imai K, Suzuki H.
  • Journal Title: Scientific Reports Volume: 6 Pages: 26699-26699
  • DOI: 10.1038/srep26699
  • Peer Reviewed / Open Access
• [Journal Article] The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway. (2016)
  • Author(s): Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, Mitsuhashi K, Igarashi H, Ito M, Tanuma T, Sukawa Y, Okita K, Hasegawa T, Imai K, Yamamoto H, Shinomura Y, Nosho K.
  • Journal Title: Oncotarget Volume: 7 Issue: 11 Pages: 12704-120717
  • DOI: 10.18632/oncotarget.7260
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer. (2016)
  • Author(s): Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y.
  • Journal Title: World J Gastroenterol Volume: 22 Pages: 557-566
  • DOI: 10.3748/wjg.v22.i2.557
  • Peer Reviewed / Open Access
• [Journal Article] Seasonal allergies and serial changes of serum levels of IgG4 in cases treated with maintenance therapy for IgG4-related disease. (2016)
  • Author(s): Yamamoto M, Takahashi H, Shimizu Y, Yajima H, Suzuki C, Naishiro Y, Imai K, Shinomura Y.
  • Journal Title: Mod Rheumatol. Volume: 26 Issue: 1 Pages: 161-2
  • DOI: 10.3109/14397595.2014.995893
  • Peer Reviewed
• [Journal Article] Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report. (2016)
  • Author(s): Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
  • Journal Title: Cancer Science Volume: 107(3) Issue: 3 Pages: 369-371
  • DOI: 10.1111/cas.12889
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2 (2016)
  • Author(s): Matsuo H, Tsunoda T, Ooyama K, Sakiyama M, Sogo T, Takada T, Nakashima A, Nakayama A, Kawaguchi M, Higashino T, Wakai K, Ooyama H, Hokari R, Suzuki H, Ichida K, Inui A, Fujimori S, Shinomiya N
  • Journal Title: Sci Rep Volume: 6 Pages: 31003-31003
  • DOI: 10.1038/srep31003
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment. (2016)
  • Author(s): Watanabe I, Kuriyama N, Miyatani F, Nomura R, Naka S, Nakano K, Ihara M, Iwai K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Tamura A, Mizuno T, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M, Tanaka T, Kanamura N, Friedland RP, Watanabe Y.
  • Journal Title: Sci Rep Volume: 6 Pages: 38561-38561
  • DOI: 10.1038/srep38561
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Ethnic Differences in Glucose Homeostasis Markers between the Kyushu-Okinawa Population Study and the Framingham Offspring Study. (2016)
  • Author(s): Ikezaki H, Ai M, Schaefer EJ, Otokozawa S, Asztalos BF, Nakajima K, Zhou Y, Liu CT, Jacques PF, L. Cupples LA, Furusyo N.
  • Journal Title: Scientific Reports Volume: 6 Pages: 36725-36725
  • DOI: 10.1038/srep36725
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Bowel Movement Frequency, Laxative Use, and Mortality From Coronary Heart Disease and Stroke Among Japanese Men and Women : The Japan Collaborative Cohort (JACC) Study (2016)
  • Author(s): Kubota Y, Iso H, Tamakoshi A
  • Journal Title: Journal of Epidemiology Volume: 26 Issue: 5 Pages: 242-248
  • DOI: 10.2188/jea.je20150123 10.2188/jea.JE20150123
  • NAID: 130005150474
  • ISSN: 0917-5040, 1349-9092
  • Peer Reviewed
• [Journal Article] The influence of personality and perceived stress on the development of breast cancer : 20-year follow-up of 29,098 Japanese women (2016)
  • Author(s): Sawada T, Nishiyama T, Kikuchi N, Wang C, Lin Y, Mori M, et al
  • Journal Title: Sci Rep Volume: 2 Pages: 32559-32559
  • DOI: 10.1038/srep32559
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Watching Television and Risk of Mortality From Pulmonary Embolism Among Japanese Men and Women : The JACC Study (Japan Collaborative Cohort) (2016)
  • Author(s): Shirakawa T, Iso H, Yamagishi K, Yatsuya H, Tanabe N, Ikehara S, et al
  • Journal Title: Circulation Volume: 134 Pages: 355-357
  • DOI: 10.1161/circulationaha.116.023671
  • Peer Reviewed
• [Journal Article] Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. (2016)
  • Author(s): Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, Okuda T, Ohara S, Murayama S, Takao M, Uchida S, Yamanaka K, Misawa H.
  • Journal Title: Sci Rep Volume: 6 Pages: 27354-27354
  • DOI: 10.1038/srep27354
  • Peer Reviewed / Open Access
• [Journal Article] Immunolocalization of Toml in relation to protein degradation systems in Alzheimer's disease. (2016)
  • Author(s): Makioka K, Yamazaki T, Takatama M, Ikeda M, Murayama S, Okamoto K, Ikeda Y.
  • Journal Title: J Neurol Sci. Volume: 365 Pages: 101-107
  • DOI: 10.1016/j.jns.2016.03.035
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans : Results from a Phase-3 Study. (2016)
  • Author(s): Seibyl J, Ishii K, Rowe CC, Leverenz JB, Ghetti B, Ironside JW, Takao M, Akatsu H, Murayama S, Bullich S, Mueller A, Koglin N, Schulz-Schaeffer WJ, Hoffmann A, Sabbagh MN, et. al
  • Journal Title: J Nucl Med Volume: 57 Pages: 900-906
  • DOI: 10.2967/jnumed.115.161927
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistanttau. (2016)
  • Author(s): Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DM, Iwatsubo T, Hasegawa M.
  • Journal Title: Acta Neuropathol. Volume: 131(2) Pages: 267-280
  • DOI: 10.1007/s00401-015-1503-3
  • NAID: 120006545236
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases. (2016)
  • Author(s): Kurosawa M, Matsumoto G, Sumikura H, Hatsuta H, Murayama S, Sakurai T, Shimogori T, Hattori N, Nukina N
  • Journal Title: Neurosci Res Volume: 103 Pages: 64-70
  • DOI: 10.1016/j.neures.2015.08.002
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The Abundance of Nonphosphorylated Tau in Mouse and Human Tauopathy Brains Revealed by the Use of Phos-Tag Method. (2016)
  • Author(s): Kimura T, Hatsuta H, Masuda-Suzukake M, Hosokawa M, Ishiguro K, Akiyama H, Murayama S, Hasegawa M, Hisanaga S.
  • Journal Title: Am J Pathol. Volume: 186 Pages: 398-409
  • DOI: 10.1016/j.ajpath.2015.10.009
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains. (2016)
  • Author(s): Kametani F, Obi T, Shishido T, Akatsu H, Murayama S, Saito Y, Yoshida M, Hasegawa M
  • Journal Title: Scientific Reports Volume: － Pages: 23281-23281
  • DOI: 10.1038/srep23281
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α561. (2016)
  • Author(s): Nishimura K, Doi D, Samata B, Murayama S, Tahara T, Onoe H, Takahashi J.
  • Journal Title: Stem Cell Reports. Volume: 6 Pages: 511-524
  • DOI: 10.1016/j.stemcr.2016.02.008
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Significant association of cadaveric dura mater grafting with subpial Abeta deposition and meningeal amyloid angiopathy. (2016)
  • Author(s): Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H, Yamada M
  • Journal Title: Acta Neuropathol Volume: 132(2) Pages: 313-315
  • DOI: 10.1007/s00401-016-1588-3
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Histopathologic analysis of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) : a report of a new genetically confirmed case and comparison to 2 previous cases. (2016)
  • Author(s): Ito S, Takao M, Fukutake T, Hatsuta H, Funabe S, Ito N, Shimoe Y, Niki T, Nakano I, Fukayama M, Murayama S
  • Journal Title: J Neuropath Exp Neurol Volume: 75 Issue: 11 Pages: 1020-1030
  • DOI: 10.1093/jnen/nlw078
  • Peer Reviewed
• [Journal Article] Extranodal NK/T-cell lymphoma, nasal type, manifesting as rapidly progressive dementia without any mass or enhancing brain lesion. (2016)
  • Author(s): Shimatani Y, Nakano Y, Tsuyama N, Murayama S, Oki R, Miyamoto R, Murakami N, Fujita K, Watanabe S, Uehara H, Abe T, Nodera H, Kawarai T, Izumi Y, Kaji R
  • Journal Title: Neuropathology Volume: 36 Pages: 456-463
  • DOI: 10.1111/neup.12285
  • Peer Reviewed / Open Access
• [Journal Article] Association of variations in HLA class Ⅱ and other loci with susceptibility to EGFR-mutated lung adenocarcinoma. (2016)
  • Author(s): Shiraishi K, Takahashi A, Takano A, Watanabe Y, Hishida T, Tsuchihara K, Miyagi Y, Tanaka K, Imai K, Minamiya Y, Sakamoto H, Inazawa J, Nakamura Y, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T, et. al.
  • Journal Title: Nature Communications Volume: 7 Pages: 12451-12451
  • DOI: 10.1038/ncomms12451
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Chemotherapy-Induced IL34 Enhances Immunosuppression by Tumor-Associated Macrophages and Mediates Survival of Chemoresistant Lung Cancer Cells. (2016)
  • Author(s): Baghdadi M, Wada H, Nakanishi S, Abe H, Han N, Putra WE, Endo D, Watari H, Sakuragi N, Hida Y, Kaga K, Miyagi Y, Yokose T, Takano A, Daigo Y, Seino KI
  • Journal Title: Cancer Res Volume: 76 Pages: 6030-6042
  • DOI: 10.1158/0008-5472.can-16-1170
  • NAID: 120006347198
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women. (2016)
  • Author(s): Wang Z, Kohno T, Yokota J, Kunitoh H, Daigo Y, Mitsudomi T, Yatabe Y, Hida T, Iwasaki M, Shimazu T, Tsugane S, Li YJ, Yang TY, Lin CC, Yu J, Shen H, Kubo M, Chanock SJ, Rothman N, Lan Q, et. al.
  • Journal Title: Hum Mol Genet Volume: 25 Pages: 620-629
  • DOI: 10.1093/hmg/ddv494
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dysregulation of c-Myb Pathway by Aberrant Expression of Proto-oncogene MYB Provides the Basis for Malignancy in Adult T-cell Leukemia/lymphoma Cells (2016)
  • Author(s): Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T.
  • Journal Title: Clin Cancer Res. Volume: 22 Pages: 5915-5928
  • DOI: 10.1158/1078-0432.ccr-15-1739
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Incidence of human T-lymphotropic virus 1 infection in adolescent and adult blood donors in Japan : a nationwide retrospective cohort analysis (2016)
  • Author(s): Satake M, Iwanaga M, Sagara Y, Watanabe T, Okuma K, Hamaguchi I
  • Journal Title: Lancet Infect Dis. Volume: 16 Pages: 1246-1254
  • DOI: 10.1016/s1473-3099(16)30252-3
  • Peer Reviewed
• [Journal Article] Polycomb-dependent epigenetic landscape in adult T-cell leukemia (2016)
  • Author(s): Fujikawa D, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Yamagishi M, Watanabe T
  • Journal Title: Blood Volume: 127 Pages: 1790-1802
  • DOI: 10.1182/blood-2015-08-662593
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] 尿酸トランスポーター遺伝子ABCG2のレアバリアントはコモンバリアンと同様に痛風リスクを上昇させる (2019)
  • Author(s): 中嶌真由子, 東野俊英, 高田龍平, 中岡博史, 豊田優, 中島宏, 清水聖子, 川口真, 中山昌喜, 河村優輔, 赤司藍理, 石野美咲, 若井建志, 岡田理恵子, 大山博司, 井ノ上逸朗, 四ノ宮成祥, 松尾洋孝
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 日本人一般集団における種類別アルコール摂取とメタポリック症候群関連要因に関する横断的研究 : J-MICC研究 (2019)
  • Author(s): 下敷領一平、指宿りえ、嶋谷圭一、西本大策、嶽崎俊郎、J-MICC Study Group
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 日本人のストレス対処行動に関するGWAS解析 : J-MICC study (2019)
  • Author(s): 島ノ江 千里、八谷剛史、原 めぐみ、須藤洋一、西田 裕一郎、清水厚志、田中 恵太郎
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 日常身体活動とコーヒー摂取が血清肝逸脱酵素に及ぼす影響 (2019)
  • Author(s): 西田裕一郎、原めぐみ、桧垣靖樹、田口尚人、中村和代、南里妃名子、今泉猛、坂本龍彦、島ノ江千里、堀田美加子、新地浩一、田中恵太郎
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 日常の身体活動および余暇時の運動とメタボリック症候群やその構成因子との関連の検討 (2019)
  • Author(s): 上村浩一、釜野桜子、岩崎夕貴、有澤孝吉
  • Organizer: 第88回日本衛生学会学術総会
• [Presentation] 大規模分子疫学コンソーシアムによる日本人 一般集団を対象とした体格指標のゲノムワイド関連解析 (2019)
  • Author(s): 後藤 温、中杤昌弘、成田 暁、山地太樹、澤田典絵、久保充明、桃沢幸秀、伊藤秀美、松尾恵太郎、丹野高三、清水厚志、實澤 篤、木下賢吾、若井建志、津金昌一郎、岩崎 基
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 前立腺がん骨転移制御分子の解析 (2019)
  • Author(s): 沢田雄一郎, 菊川忠彦, 飯尾浩之, 榊原伊織, 吉田周平, 池戸葵, 柳原裕太, 佐伯法学, Balázs Gyōrffy, 岸田健, 大久保陽一郎, 中村圭靖, 宮城洋平, 雑賀隆史, 今井祐記
  • Organizer: 第9回Orthopaedic Research Club
• [Presentation] 森林散策による高血圧症予防の検証 : 大規模疫学調査J-MICC Study静岡地区 (2019)
  • Author(s): 森田えみ、川合紗世
  • Organizer: 第130回日本森林学会大会
• [Presentation] 脂肪肝の簡易指標であるFatty liver indexと慢性炎症や動脈スティフネスとの関連 (2019)
  • Author(s): 上村浩一、釜野桜子、岩崎夕貴、有澤孝吉
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 血漿ビタミンB12濃度の個人内および個人間変動 : J-MICC Sakura Diet Study (2019)
  • Author(s): 遠藤 香, 栗木清典
  • Organizer: 第29回 日本疫学会学術総会
• [Presentation] 果物の種類別摂取頻度と循環器疾患死亡リスクとの関連 : The JACC Study (2019)
  • Author(s): 村井詩子, 山岸良匡, 村木功, 磯博康, 玉腰暁子
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 一般住民女性における非アルコール性脂肪肝と肝線維化に関する前向き研究 (2019)
  • Author(s): 指宿りえ、下敷領一平、Yora Nindita、西本大策、嶋谷圭一、前之原茂穂、嶽崎俊郎
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 遺伝因子と飲酒量の交互作用と随時血圧値の関連 -東北メディカル・メガバンク計画地域住民コホート調査- (2019)
  • Author(s): 成田 暁、中谷直樹、小暮真奈、田宮 元、中村智洋、土屋菜歩、平田 匠、丹野高三、坂田清美、菅原準一、栗山進一、辻 一郎、呉 繁夫、寳澤 篤
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 妊娠中のストレスと生後の疾患の関連について (2019)
  • Author(s): 宇田川潤
  • Organizer: 第28回滋賀県母性衛生学会学術集会
  • Invited
• [Presentation] 糖質コルチコイドの大規模LCMS測定 (2019)
  • Author(s): 松本明子、赤尾千穂
  • Organizer: 第7回久留米佐賀熊本合同研究会
• [Presentation] グルタミン代謝制御遺伝子Glutaminase2が癌・老化関連疾患に及ぼす影響 (2019)
  • Author(s): 鈴木佐和子、横手幸太郎
  • Organizer: 第19会日本抗加齢医学会総会
  • Invited
• [Presentation] Radiological and pathological evaluation of cerebral vasculopathy in POEMS syndrome (2019)
  • Author(s): 杉山淳比古、横田元、三澤園子、齊藤祐子、松島淳、向井宏樹、関口縁、小出恭輔、伊藤彰一、桑原聡
  • Organizer: 第48回日本神経放射線学会
• [Presentation] GPRC5Aは前立腺癌の細胞増殖および骨転移を制御する (2019)
  • Author(s): 沢田雄一郎, 菊川忠彦, 飯尾浩之, 榊原伊織, 吉田周平, 池戸葵, 柳原裕太, 佐伯法学, Balázs Gyōrffy, 岸田健, 大久保陽一郎, 中村圭靖, 宮城洋平, 雑賀隆史, 今井祐記
  • Organizer: 第28回泌尿器科分子・細胞研究会
• [Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer (2019)
  • Author(s): Sawada Y, Kikugawa T, Iio H, Yanagihara Y, Saeki N, Sakakibara I, Gyōrffy B, Kishida T, Miyagi Y, Saika T, Imai Y
  • Organizer: the 34th Annual The European Association of Urology Congress
  • Int'l Joint Research
• [Presentation] Development of analytical tools for glyco-neuroscience (2019)
  • Author(s): Akira Minami
  • Organizer: ZUCKERfest2019 in UC Berkeley
  • Int'l Joint Research / Invited
• [Presentation] 非喫煙者における受動喫煙と高血圧との関連 : 日本多施設共同コーホート研究(J-MICC Study) (2019)
  • Author(s): 田村高志, 門松由佳, 塚本峰子, 久保陽子, 岡田理恵子, 篠壁多恵, 川合紗世, 菱田朝陽, 内藤真理子, 若井建志, 日本多施設共同コーホート研究実施グループ
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 特発性正常圧水頭症における食後髄液中糖濃度はtau濃度と相関する (2019)
  • Author(s): 西田 南海子、永田 奈々恵、陣上 直人、戸田 弘紀、石川 正恒、松本 禎之、岩崎 孝一
  • Organizer: 第20回日本正常圧水頭症学会
• [Presentation] 単一細胞分析データマイニングによるHTLV-1持続潜伏感染機構の解明 (2019)
  • Author(s): 佐藤賢文
  • Organizer: 平成30年度HTLV-1関連疾患研究領域研究班合同発表会
  • Invited
• [Presentation] 腎糸球体の過剩濾過(hyperfiltration)と高血圧前症および糖尿病前症との関連 : J-MICC Study (2019)
  • Author(s): 門松由佳, 塚本峰子, 久保陽子, 田村高志, 岡田理恵子, 篠壁多恵, 川合紗世, 菱田朝陽, 内藤真理子, 若井建志, 日本多施設共同コーホート研究実施機関
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 住民健診受診者における糖代謝指標値と白血球中TXNIP遺伝子のDNAメチル化率との関連 (2019)
  • Author(s): 前田圭介、山田宏哉、宗綱栄二、山崎未来、水野元貴、大橋鉱二、石川浩章、安藤嘉崇、藤井亮輔、萩原千晴、橋本修二、浜島信之、鈴木康司
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 住民健診受診者における前頭葉機能検査と血清BDNF値との関連 (2019)
  • Author(s): 萩原 千晴、山田宏哉、藤井亮輔、近藤真理、前田圭介、橋本修二、浜島信之、鈴木康司
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 次世代DNAシークエンス技術を活用したウイルス研究 (2019)
  • Author(s): 佐藤賢文
  • Organizer: 第66回日本生態学会大会
• [Presentation] 脂質異常症治療薬使用の糖尿病発症リスクに関するメタボローム疫学研究 (2019)
  • Author(s): 松元美奈子、原田成、栗原綾子、飯田美穂、加藤寿寿華、佐田みずき、澁木琢磨、桑原和代、竹内文乃、杉山大典、岡村智教、武林亨
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 高血圧患者の塩分制限と関連する遺伝子多型の探索・J-MICC横断研究 (2019)
  • Author(s): 中根英雄, 若井建志
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 血漿葉酸、ホモシステイン、ビタミンB12値関連遺伝子多型と飲酒、喫煙との交互作用 : J-MICC Study (2019)
  • Author(s): 塚本峰子, 門松由佳, 田村高志, 久保陽子, 岡田理恵子, 篠壁多恵, 川合紗世, 菱田朝陽, 内藤真理子, 若井建志
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 一般住民におけるBNIのストレスに対する影響(メンデルランダム化解析) : J-MICC研究(Study) (2019)
  • Author(s): 成定明彦, 鈴木孝太, 若井建志
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] アルツハイマー病危険因子APOEの認知機能や長寿に対する作用 (2019)
  • Author(s): 篠原 充
  • Organizer: 第20回関西・中部認知症研究会
• [Presentation] アソシエーション分析を用いた既往疾患のco-morbidityの評価 (2019)
  • Author(s): 菅原妙, 近藤高明, 上山純, 岡田理恵子, 菱田朝陽, 森田えみ, 川合紗世, 浜島信之, 内藤真理子, 若井建志
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] HTLV-1感染病態解明へ向けた感染者血液のシングルセル解析 (2019)
  • Author(s): 佐藤賢文
  • Organizer: 第4回鹿児島大学感染症制御のためのシンポジウム
  • Invited
• [Presentation] HTLV-1感染病態解明へ向けた感染者血液のシングルセルトランスクリブトーム解析 (2019)
  • Author(s): 佐藤賢文
  • Organizer: 【AMED新興再興】新興再興感染症制御PJ(3事業)合同シンボジウム
• [Presentation] GWAS of serum PSA level as a quantitative trait in Japanese-data from the J-MICC Study (2019)
  • Author(s): Hishida A, Nakatochi M, Okada R, Tamura T, Kadomatsu Y, Tsukamoto M, Kubo Y, Sasakabe T, Kawai S, Naito M, Wakai K
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] Tau-related dysfunction of BRCA1 lead to reduced neuronal plasticity in Alzheimer's disease (2018)
  • Author(s): Tatsuo Mano, Atsushi Iwata, Takashi Nonaka, Airi Tarutani, Tadafumi Hashimoto, Masato Hasegawa, Takeshi Iwatsubo, Tatsushi Toda
  • Organizer: American Academy of Neurology 70th Annual Meeting
  • Int'l Joint Research
• [Presentation] Tau-related dysfunction of BRCA1 lead to reduced neuronal plasticity in Alzheimer's disease (2018)
  • Author(s): Tatsuo Mano, Atsushi Iwata, Takashi Nonaka, Airi Tarutani, Tadafumi Hashimoto, Masato Hasegawa, Takeshi Iwatsubo, Tatsushi Toda
  • Organizer: AAIC2018
  • Int'l Joint Research
• [Presentation] 老化脳に蓄積する希少糖分子が認知症に及ぼす影響の解明 (2018)
  • Author(s): 横山 喬太, 南 彰, 三上 靖代, 吉村 満里菜, 海野けい子, 大坪 忠宗, 池田 潔, 鈴木 隆
  • Organizer: 糖鎖科学名古屋拠点 第15回『若手の力』フォーラム
• [Presentation] 老化脳に蓄積する希少糖分子がアミロイドβ蓄積に及ぼす影響の解明 (2018)
  • Author(s): 横山 喬太, 南 彰, 三上 靖代, 吉村 満里菜, 海野けい子, 大坪 忠宗, 池田 潔, 鈴木 隆
  • Organizer: 日本病院薬剤師会東海ブロック・日本薬学会東海支部 合同学術大会2018
• [Presentation] 慢性胃炎および胃がんに関連する長鎖non-coding RNAの同定と機能解析 (2018)
  • Author(s): 北嶋洋志, 丸山玲緒, 山本英一郎, 新沼猛, 甲斐正広, 佐々木泰史, 時野隆至, 仲瀬裕志, 鈴木拓
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] 非アルコール性脂肪性肝疾患の経時的変化の男女差に関するコーホート研究 (2018)
  • Author(s): 指宿りえ、下敷領一平、西本大策、嶽﨑俊郎
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 肺がんの低酸素応答における浸潤のメカニズム (2018)
  • Author(s): 片岡 瑛子、大塩 恭彦、林 一喜、岡本 圭伍、賀来 良輔、五十嵐 知之、寺本 晃治、花岡 淳
  • Organizer: 第35回日本呼吸器外科学会総会
• [Presentation] 脳脊髄液減少症における髄液バイオマーカー (2018)
  • Author(s): 村上友太、星 京香、伊藤浩美、齋藤 清、宮嶋雅一、新井 一、高橋浩一、美馬達夫、光藤 尚、荒木信夫、橋本康弘
  • Organizer: 第71回日本自律神経学会総会
  • Invited
• [Presentation] 統合失調症死後脳におけるALDH4A1についてのジェネティックニューロパソロジー (2018)
  • Author(s): 長岡敦子、國井泰人、日野瑞城、松本純弥、丹羽真一、竹島明、那波宏之、柿田明美、矢部博興
  • Organizer: 第40回 日本生物学的精神医学会
  • Invited
• [Presentation] 都市住民における緑地環境へのふれあいとメンタルヘルスとの関連 : J-MICC Study 大幸研究 (2018)
  • Author(s): 森田えみ、若井建志、川合紗世、岡田理恵子、田村高志、篠壁多恵、内藤真理子
  • Organizer: 第59回 日本心身医学会総会ならびに学術講演会
• [Presentation] 地域在宅高齢者の認知機能と血清葉酸濃度の関連 : J-MICC Study静岡・桜ヶ丘地区 (2018)
  • Author(s): 遠藤 香, 栗木清典, for Shizuoka-Sakuragaoka J-MICC Study Group
  • Organizer: 第65回日本栄養改善学会学術総会
• [Presentation] 精神疾患死後脳研究の実際 (2018)
  • Author(s): 國井泰人
  • Organizer: 第40回 日本生物学的精神医学会
  • Invited
• [Presentation] 精神疾患死後脳研究 : ジェネティックニューロパソロジー及びリソース利用の有用性 (2018)
  • Author(s): 國井泰人
  • Organizer: 第40回 日本生物学的精神医学会
  • Invited
• [Presentation] 精神科臨床と死後脳とを結ぶ研究とは (2018)
  • Author(s): 國井泰人
  • Organizer: 第114回日本精神神経学会総会学術総会
  • Invited
• [Presentation] 成人T細胞性白血病・リンパ腫診療の現状と今後～HTLV-1キャリアからATL治療まで～ (2018)
  • Author(s): 内丸薫
  • Organizer: 第5回日本HTLV-1学会学術集会
  • Invited
• [Presentation] 髄液糖鎖マーカーとしての脳型トランスフェリン (2018)
  • Author(s): 村上友太、星 京香、伊藤浩美、不破尚志、安部英理子、齋藤 清、宮嶋雅一、新井 一、光藤 尚、荒木信夫、高橋浩一、美馬達夫、橋本康弘
  • Organizer: 第12回東北糖鎖研究会
• [Presentation] 髄液代謝異常症とトランスフェリン糖鎖異性体 (2018)
  • Author(s): 村上友太、高橋浩一、星 京香、伊藤浩美、不破尚志、菅野真由美、山口芳樹、宮嶋雅一、新井 一、美馬達夫、本多たかし、齋藤 清、橋本康弘
  • Organizer: 第37回日本糖質学会年会
• [Presentation] 髄液産生マーカーとしてのトランスフェリン (2018)
  • Author(s): 村上友太、高橋浩一、星 京香、伊藤浩美、宮嶋雅一、新井 一、美馬達夫、本多たかし、齋藤 清、橋本康弘
  • Organizer: 京都髄液フォーラム2018
• [Presentation] 新しい脳脊髄液代謝マーカーによる脳脊髄液漏出症の診断 (2018)
  • Author(s): 村上友太、高橋浩一、星 京香、伊藤浩美、齋藤 清、山口芳樹、宮嶋雅一、新井 一、美馬達夫、橋本康弘
  • Organizer: BIO Japan 2018
• [Presentation] 新しい髄液代謝マーカー : 髄液過剰による認知症及び髄液漏出症の診断 (2018)
  • Author(s): 村上友太、高橋浩一、星 京香、伊藤浩美、齋藤 清、山口芳樹、宮嶋雅一、新井 一、美馬達夫、橋本康弘
  • Organizer: BIO tech 2018
• [Presentation] 次世代HTLV-1クロナリティ解析法の開発とその応用に向けて (2018)
  • Author(s): 斎藤益満、山内俊輔、佐々木大介、長谷川寛雄
  • Organizer: 第5回日本HTLV-1学会
• [Presentation] 現在のBMIおよび20歳からのBMIの増加と簡略更年期指数との関連 : J-MICC Study静岡・桜ヶ丘地区 (2018)
  • Author(s): 川田久美子, 中野夏菜, 秋元 柊, 遠藤 香, 栗木清典
  • Organizer: 第65回日本栄養改善学会学術総会
• [Presentation] 血清HDL-C濃度と生活習慣および遺伝子要因の関連に対する季節の影響 : J-MICC Sakura Diet Study (2018)
  • Author(s): 秋元 柊, 遠藤 香, 後藤千穂, 栗木清典
  • Organizer: 第65回日本栄養改善学会学術総会
• [Presentation] 希少シアル酸分子種は老化脳に蓄積しアミロイドの凝集を促進する (2018)
  • Author(s): 三上 靖代, 南 彰, 横山 喬太, 吉村 満里菜, 石井 亜実, 大坪 忠宗, 池田 潔, 鈴木 隆
  • Organizer: 糖鎖科学名古屋拠点 第15回『若手の力』フォーラム
• [Presentation] 癌の悪性か・難治化に関与する新規因子IL-34に関する研究. (2018)
  • Author(s): 清野研一郎.
  • Organizer: 第46回日本臨床免疫学会総会
• [Presentation] 海藻の摂取頻度と循環器疾患死亡リスクとの関連 : JACC研究 (2018)
  • Author(s): 臼杵里恵, 村木功, 山岸良匡, 玉腰暁子, 磯博康
  • Organizer: 第54回日本循環器病予防学会学術集会
• [Presentation] 沖縄型神経原性筋萎縮性側索硬化症4例の 臨床神経病理学的検討 (2018)
  • Author(s): 村山繁雄、○諏訪園秀吾、熱海恵理子、中地亮、藤原善寿, 藤暗なつみ、城戸美和子、渡嘉敷崇、松原知康、和泉唯信、齊藤祐子
  • Organizer: 厚生労働科学研究費補助金難治性疾患等政策研究事業(難治性疾患政策研究事業)神経変性疾患領域における 基盤的調査研究班平成30年度班会議
• [Presentation] 一般成人健常者におけるロコモ度テスト判定と筋力測定結果について (2018)
  • Author(s): 尾崎悦子、栗山長門、松井大輔、小山晃英、渡邉功、長光玲央、富田仁美、渡邊能行
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 悪性リンパ腫における EZH1/EZH2依存的なエピゲノム異常と創薬 (2018)
  • Author(s): 山岸誠
  • Organizer: 第22回日本がん分子標的治療学会学術集会、Anti-Cancer Trestment Japan 合同シンポジウム
  • Int'l Joint Research / Invited
• [Presentation] 悪性がんのバイオマーカーとしてのラミニンγ2単鎖 (2018)
  • Author(s): 越川直彦
  • Organizer: 第27回日本がん転移学会学術集会会長講演
  • Invited
• [Presentation] マーモセット脳におけるタウのアイソフォーム発現とリン酸化 : アルツハイマー病霊長類モデルとなりうるか (2018)
  • Author(s): Hisanaga, S., Shiozawa, S., Kobayashi, R., Murayama, S.,. Saito, T., Ando, K., Okano, H., Kimura, T., Sharma, G.
  • Organizer: 第60回日本神経化学会大会
  • Invited
• [Presentation] ヒト短時間睡眠における骨量低カリスク因子の検討 (2018)
  • Author(s): 栗山長門、尾崎悦子、稲葉雅章、山田真介、堀井基行、黒川正夫、松井大輔、小山晃英、米田勇太郎、渡邊能行.
  • Organizer: 第20回日本骨粗鬆症学会.
• [Presentation] 早期アルツハイマー病理を呈する患者脳における神経炎症関連遺伝子発現解析 (2018)
  • Author(s): 祖父江顕、遠藤史人、小峯起、村山繁雄、山中宏二
  • Organizer: 第37回日本認知症学会学術集会
• [Presentation] 献血者から見出された抗体陰性HTLV-1キャリア (2018)
  • Author(s): 相良康子、中村仁美、倉光球、相良康弘、松永克希、平山秀明、島村益弘、岩永正子、大隈和、浜口功、入田和男
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] 血清25ヒドロキシビタミンD欠乏と食生活・食品摂取頻度との検討 (2018)
  • Author(s): 尾崎悦子
  • Organizer: 第65回日本栄養改善学会学術総会
• [Presentation] グルタミン代謝の生活習慣病と癌における役割とその分子病態 (2018)
  • Author(s): 鈴木佐和子
  • Organizer: 第18回TCカンファランス
• [Presentation] がん罹患歴と朝型夜型との関連 (2018)
  • Author(s): 森田えみ、山田尚登、角谷寛、若井建志、川合紗世、岡田理恵子、田村高志、内藤真理子
  • Organizer: 日本睡眠学会第43回定期学術集会
• [Presentation] エビ・カニアレルギーに関する日本人のゲノムワイド関連解析 (2018)
  • Author(s): 賈 慧娟、野川 駿、高橋 祥子、斉藤 憲司、加藤 久典
  • Organizer: 第72回日本栄養・食糧学会大会
• [Presentation] 一般健常人の骨測定・骨マーカーの5年追跡結果 (2018)
  • Author(s): 尾崎悦子、栗山長門、山田真介、松井大輔、小山晃英、渡邉功、今西康雄、稲葉雅章、渡邊能行
  • Organizer: 第20回日本骨粗鬆症学会
• [Presentation] 胃がんリスク層別化検査(ABC分類)と動脈硬化度との関連の検討 (2018)
  • Author(s): 長光玲央、栗山長門、小山晃英、松井大輔、尾崎悦子、渡邉功、岩井浩明、富田仁美、渡邊能行
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] V180I変異Creutzfeldt-Jakob病の86歳女性剖検例-18F THK5351 PETによる検討. (2018)
  • Author(s): 白石朋敬、坂下泰浩、仁科裕史、仙石錬平、石井賢二、徳丸阿耶、金丸和富、村山繁雄
  • Organizer: 第224回日本神経学会関東・甲信越地方会
• [Presentation] The role of Interleukin-34 in ovarian cancer. (2018)
  • Author(s): Naoki Hama, Muhammad Baghdadi, Kozo Ishikawa, Hiraku Endo, Haruka Wada, Ken-ichiro Seino.
  • Organizer: The 45th Naito Conference on “Immunological and Molecular Bases for Cancer Immunotherapy”
• [Presentation] The role of IL-34 in colorectal cancer. (2018)
  • Author(s): Takuto Kobayashi, Muhammad Baghdadi, Kozo Ishikawa, Nanumi Han, Haruka Wada, Ken-ichiro Seino.
  • Organizer: The 45th Naito Conference on “Immunological and Molecular Bases for Cancer Immunotherapy”
• [Presentation] The nature of HTLV-1 provirus in infected individuals analyzed by HTLV-1 DNA capture sequencing (2018)
  • Author(s): 勝屋弘雄、イスラム サイフル、宮里パオラ、タンペンジー・ジェック・ヤング、岩瀬早織、松尾美沙希、佐藤知雄、野坂生郷、徳永雅仁、宇都宮與、山岸誠、内丸薫、渡邉俊樹、山野嘉久、佐藤賢文
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] The association of PSCA gene and H. pylori-related gastric atrophy risk detected by GWAS and SKAT (2018)
  • Author(s): Hishida A, Fujii R, Nakatochi M, Kawai S, Ito H, Matsuo K, Watanabe M, Suzuki S, Kuriyama N, Naito M, Wakai K
  • Organizer: The 77th Annual Meeting of the Japanese Cancer Association(第77回日本癌学会学術総会)
• [Presentation] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD (2018)
  • Author(s): Motomasa Tanaka
  • Organizer: Post ICN Neuroscience Meeting
  • Int'l Joint Research / Invited
• [Presentation] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD (2018)
  • Author(s): Motomasa Tanaka
  • Organizer: International Symposium on “Proteins ; from the Cradle to the Grave”
  • Int'l Joint Research
• [Presentation] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD (2018)
  • Author(s): Endo, R., Takashima, N., Nekooki-Machida, Y., Komi, Y., Hui, K. K., Takao, M., Akatsu, H., Murayama, S., Sawa, A., and Tanaka, M.
  • Organizer: 第18回日本蛋白質科学会年会
  • Invited
• [Presentation] Relationship between meat and fish intakes and dyslipidemia in a General Japanese Population : Results of Takashima Cohort Study (2018)
  • Author(s): Tomiyo Nakamura, Yasuyuki Nakamura, Yoshikuni Kita, and Hirotsugu Ueshima
  • Organizer: BIT's 7th Annual World Congress of Food and Nutrition-2018
  • Int'l Joint Research
• [Presentation] Profile of the GCOP Study : A genome cohort on psychosocial traits in a dimensional perspective. (2018)
  • Author(s): Takeshi Nishiyama, Chaochen Wang, Asahi Hishida, Miki Watanabe, Hiroko Nakagawa, Sho Nakamura, Kayoko Katayama, Hiroto Narimatsu, Sadao Suzuki.
  • Organizer: ASHG2018
  • Int'l Joint Research
• [Presentation] Possible application of gene therapy to sporadic neurological diseases-ALS as a prototype (2018)
  • Author(s): 郭 伸
  • Organizer: 第24回日本遺伝子細胞治療学会
  • Invited
• [Presentation] Novel CSF biomarkers for diagnosing Spontaneous intracranial hypotension : combination of lipocalin-type prostaglandin D synthase & brain-type transferrin (2018)
  • Author(s): Yuta Murakami, Koichi Takahashi, Kyoka Hoshi, Hiromi Ito, Kiyoshi Saito, Masakazu Miyajima, Hajime Arai, Tatuo Mima, Yasuhiro Hashimoto
  • Organizer: The 10th Meeting of the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders (Hydrocephalusd 2018)
  • Int'l Joint Research
• [Presentation] Neuron-specific histone modification analysis of sporadic Alzheimer's disease (2018)
  • Author(s): Kagari Mano, Tatsuo Mano. Atsushi Iwata, Shigeo Murayama, Tatsushi Toda
  • Organizer: AAIC2018
  • Int'l Joint Research
• [Presentation] Neuron-specific histone modification analysis of Alzheimer's diseae brain (2018)
  • Author(s): Kagari Mano, Tatsuo Mano, Atsushi Iwata, Shigeo Murayama, Tatsushi Toda
  • Organizer: 19th International Congress of Neuropathology
  • Int'l Joint Research
• [Presentation] Minor sialic acid molecular species promote aggregation of amyloid in the brain (2018)
  • Author(s): Yasuyo Mikami, Akira Minami, Kyota Yokoyama, Marina Yoshimura, Ami Ishii, Tadamune Otsubo, Kiyoshi Ikeda, Hiroaki Kanazawa and Takashi Suzuki
  • Organizer: The 4th International Conference on Pharma-Food (ICPF 2018)
  • Int'l Joint Research
• [Presentation] Minor sialic acid molecular species accumulate in the aging brain and promote aggregation of amyloid (2018)
  • Author(s): Yasuyo Mikami, Akira Minami, Kyota Yokoyama, Marina Yoshimura, Ami Ishii, Tadamune Otsubo, Kiyoshi Ikeda, Hiroaki Kanazawa and Takashi Suzuki
  • Organizer: The 23nd Sshizuoka forum on health and longevity
  • Int'l Joint Research
• [Presentation] JSPFADデータベースの現状報告 (2018)
  • Author(s): 岩永正子、内丸薫、中島誠、堀部恵梨佳、中野和民、山岸誠、高起良、相良康子、宇都宮與、渡邉俊樹
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] Impact of dietary folate intake on the risk of gastric cancer. (2018)
  • Author(s): Yumiko Kasugai, Tomotaka Ugai, Isao Oze, Yuriko N, Koyanagi, Hidemi Ito, Keitaro Matsuo
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] IL-34 correlates with therapeutic resistance, disease progression, and poor survival in lung cancers. (2018)
  • Author(s): Nuhammad Baghdadi, Ken-ichiro Seino.
  • Organizer: The 6th JCA-AACR Special Joint Conference.
  • Int'l Joint Research
• [Presentation] IL-34 correlates with therapeutic resistance, disease progression, and poor prognosis in lung cancer. (2018)
  • Author(s): ムハンマド・パグダーディー、和田はるか、清野研一郎
  • Organizer: 第22回日本がん免疫学会総会
• [Presentation] Identification of URST1 as a biomarker and therapeutic target for lung cancer (2018)
  • Author(s): Atsushi Takano, Yohei Miyagi, Yataro Daigo
  • Organizer: 第79回日本癌学会学術集会
• [Presentation] Identification of OASEP1 as a biomarker and therapeutic target for oral cancer (2018)
  • Author(s): Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yoshei Miyagi, Yataro Daigo
  • Organizer: 第63回 日本人類遺伝学会
• [Presentation] HTLV-1関連疾患の発症メカニズムにおけるJAK-STAT経路の機能的意義の検討 (2018)
  • Author(s): 石崎伊純、山岸 誠、志賀遥菜、新谷奈津美、宇都宮 與、中村龍文、田中勇悦、山野嘉久、渡邉俊樹、内丸 薫
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] HTLV-1感染者血清における超微量抗体のプロファイリング (2018)
  • Author(s): 松永智子、菱澤方勝、高折晃史、梁明秀
  • Organizer: 第66回日本ウイルス学会
• [Presentation] High-resolution imaging of primate brains using FAST (2018)
  • Author(s): 橋本均、勢力薫、笠井淳司、中澤敬信、井上謙一、高田昌彦
  • Organizer: 国際ワークショップ「遺伝子導入技術の利用による霊長類脳機能操作とイメージング」
  • Int'l Joint Research
• [Presentation] Hepatic steatosis indexやFatty liver indexと慢性炎症や動脈スティフネスとの関連 (2018)
  • Author(s): 上村浩一、釜野桜子、有澤孝吉
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] Genome-wide association study of shellfish allergy in Japanese population (2018)
  • Author(s): K. Saito, H. Jia, S. Nogawa, K. Kawafune, S. Takahashi, H. Kato
  • Organizer: American Society of Human Genetics 2018
  • Int'l Joint Research
• [Presentation] Development of an epigenetic drug against ATL (2018)
  • Author(s): Makoto Yamagishi
  • Organizer: IRVA Tokyo Conference 2018 & International Symposium
  • Int'l Joint Research / Invited
• [Presentation] Clinical and neuropathologic analysis of 67-year-old Japanese FTLD-ALS male associated with C9orf72 hexanucleotide repeat expansion, A second autopsy case in Japan. (2018)
  • Author(s): Ryota Sato, Masaki Takao, Masatoshi Omoto, Takashi Kanda
  • Organizer: 11th International Conference on Frontotemporal Dementia
  • Int'l Joint Research
• [Presentation] CKDリスクに対する血糖調整遺伝子多型と甘未摂取の交互作用 : J-MICC Studyの全国SNP横断研究からの知見 (2018)
  • Author(s): 中野夏菜
  • Organizer: 第3回ゲノムコホート研究における遺伝統計学(岩手大医科大学主催、徳島大学医学部共催)
• [Presentation] CKDリスクに対する血糖調整遺伝子多型と甘未摂取の交互作用 : J-MICC Studyの全国SNP横断研究 (2018)
  • Author(s): 中野夏菜, 川田久美子, 秋元 柊, 遠藤 香, 栗木清典
  • Organizer: 第65回日本栄養改善学会学術総会
• [Presentation] Characterization of URST1 as a prognostic biomarker and therapeutic target for oral cancer (2018)
  • Author(s): Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo
  • Organizer: 2018 AACR annual meeting
  • Int'l Joint Research
• [Presentation] Characterization of URST1 as a biomarker and therapeutic target for lung cancer and oral cancer (2018)
  • Author(s): Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yohei Miyagi, Yataro Daigo
  • Organizer: 第16回日本臨床腫瘍学会学術集会
• [Presentation] CD4+CADM1+細胞集団の割合はHTLV-1キャリアおよびindolent ATLの予後を予測する (2018)
  • Author(s): 牧山 純也, 小林誠一郎, 渡邊絵理, 石垣知寛, 川俣豊隆, 中嶋誠, 山岸誠, 中野和民, 東條有伸, 渡邊俊樹, 内丸薫
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] ATL及びHAM発症に至る遺伝子発現異常の推移と運命制御メカニズム (2018)
  • Author(s): 山岸誠、新谷奈津美、石崎伊純、小林誠一郎、牧山純也、佐藤知雄、八木下尚子、宇都宮與、中村龍文、田中勇悦、渡邉俊樹、山野嘉久、内丸薫
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] ATL患者血中エクソソーム担い法されるmiRNA/mRNAプロファイリング (2018)
  • Author(s): 中野和民, 宇都宮與, 渡邊俊樹, 内丸薫
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] An autopsy case of hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P, or HMSN Okinawa type). (2018)
  • Author(s): Suwazono S, Matsubara T, Nakachi R, Atsumi E, Izumi Y, Kido M, Tokashiki T, Kaji R, Yoshida M, Murayama S
  • Organizer: 19th International Congress of Neuropathology
  • Int'l Joint Research
• [Presentation] 5年間の精神ストレスとCRPの関連は、対処行動や社会的支援の変化により異なる (2018)
  • Author(s): 島ノ江 千里、原 めぐみ、西田 裕一郎、南里 妃名子、安方 惇、三好信行、山田陽介、桧垣靖樹、田中 恵太郎
  • Organizer: 第88回日本衛生会学術総会
• [Presentation] 18F-THK5351 PETで錐体路に沿った集積を認めた膠芽腫の臨床病理学的考察 (2018)
  • Author(s): 白石朋敬、仙石錬平、松原知康、石井賢二、金丸和富、村山繁雄
  • Organizer: 第59回日本神経学会学術大会
• [Presentation] 18F-THK5351 PET findings in familial Creutzfeldt-Jakob disease with V180I mutation : a cliniclpathological study. (2018)
  • Author(s): Shiraishi, T., Sengoku, R., Sakashita, Y., Nishina, Y., Ishii, K., Kanemaru, K., Murayama, S.
  • Organizer: 19th International Conference of Neuropathology 2018
  • Int'l Joint Research
• [Presentation] JSPFADデータベースの現状報告 (2018)
  • Author(s): 岩永正子, 内丸薫, 中島 誠, 堀部恵梨佳, 中野和民, 山岸 誠, 高 起良, 相良康子, 宇都宮 與, 渡邉俊樹, JSPFAD研究協力施設の先生方
  • Organizer: 第5回日本HTLV-1学会学術集会
• [Presentation] Interleukin-34 correlates with tumor progression and poor survival in cancer. (2018)
  • Author(s): Nuhammad Baghdadi, Kozo Ishikawa, Hiraku Endo, Haruka Wada, Ken-ichiro Seino.
  • Organizer: The 45th Naito Conference on “Immunological and Molecular Bases for Cancer Immunotherapy”
• [Presentation] Prediction model for pancreatic cancer risk in the general Japanese population (2018)
  • Author(s): Yingsong Lin, Masahiro Nakatochi, Hidemi Ito, Fumie Kinoshita, Yumiko Kobayashi, Hiroshi Ishii, Naoki Sasahira, Makoto Ueno, Naoto Egawa, Sawako Kuruma, Haruhisa Nakao, Fumihiko Matsuda, Shogo Kikuchi, Keitaro Matsuo
  • Organizer: The fifth AACR Special Conference on pancreatic cancer
  • Int'l Joint Research
• [Presentation] 緑茶摂取による血糖降下作用に関するシステマティックレビュー (2018)
  • Author(s): 嶌 美幸, 可児美月, 野神さくら, 川田久美子, 中野夏菜, 秋元 柊, 坂下友理, 遠藤 香, 栗木清典
  • Organizer: 第7回日本栄養改善学会東海支部会学術総会
• [Presentation] 非小細胞肺がんにおける血中可溶性PD-L1の継時的変動について (2018)
  • Author(s): 寺本晃治、五十嵐知之、住本秀敏、醍醐弥太郎
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] 非小細胞肺がんにおけるがん関連線維芽細胞のPD-L1発現制御 (2018)
  • Author(s): 寺本晃治、五十嵐知之、住本秀敏、醍醐弥太郎
  • Organizer: 日本人類遺伝学会 第63回大会
• [Presentation] 非小細胞肺がんにおけるがん関連線維芽細胞のPD-L1発現 (2018)
  • Author(s): 寺本晃治、五十嵐知之、住本秀敏、醍醐弥太郎
  • Organizer: 第16回日本臨床腫瘍学会学術集会
• [Presentation] 肥満予防のための腸内細菌叢とたんぱく質摂取に関するシステマティックレビュー (2018)
  • Author(s): 野神さくら, 嶌 美幸, 可児美月, 中野夏菜, 川田久美子, 秋元 柊, 坂下友理, 遠藤 香, 栗木清典
  • Organizer: 第7回日本栄養改善学会東海支部会学術総会
• [Presentation] 日本人一般集団における飲酒量と検診結果の関連に関する横断的研究 : J-MICC研究より (2018)
  • Author(s): 下敷領一平, 指宿りえ, 西本大策, 内藤真理子, 若井建志, 嶽崎俊郎, J-MICC Srudy Group
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 日本人の肥満に対する食物繊維摂取と腸内細菌叢組成の関連 : 横断研究 (2018)
  • Author(s): 坂下友理, 秋元 柊, 川田久美子, 中野夏菜, 後藤千穂, 遠藤 香, 栗木清典
  • Organizer: 第7回日本栄養改善学会東海支部会学術総会
• [Presentation] 早期乳がん予後予測バイオマーカーTP53 signatureの簡易測定法の開発と分子生物学的意義 (2018)
  • Author(s): 山口 茂夫、高橋 信、石田 孝宜、角川 陽一郎、野水 整、大内 憲明、加藤 俊介、石岡 千加史
  • Organizer: 第26回日本乳癌学会学術集会
• [Presentation] 早期アルツハイマー病におけるタウ病変の進展は活性化ミクログリアを誘導する (2018)
  • Author(s): 寺田達弘、小尾智一、横倉正倫、武内智康、島田斉、須原哲也、樋口真人、松平敬史、尾内康臣
  • Organizer: 第37回日本認知症学会学術集会
• [Presentation] 職域健診受診者における喫煙の動脈硬化性疾患発症リスクに関する検討 : Cardio-Ankle Vascular Index (CAVI). (2018)
  • Author(s): 桑原和代、杉山大典、平田あや、鈴木賢二、岡村智教
  • Organizer: 第50回日本動脈硬化学会総会・学術集会
• [Presentation] 受容体チロシンキナーゼのプロセシング断片によるがん悪性化進展制御の解明とその特異抗体の医療応用 (2018)
  • Author(s): 越川直彦
  • Organizer: 受容体チロシンキナーゼのプロセシング断片によるがん悪性化進展制御の解明とその特異抗体の医療応用
  • Invited
• [Presentation] 質量顕微鏡で見えてくるブレインサイエンス (2018)
  • Author(s): 瀬藤光利
  • Organizer: 鹿児島ブレインサイエンスカンファレンス
  • Invited
• [Presentation] 次世代シークエンスを活用したレトロウイルス研究 (2018)
  • Author(s): 佐藤賢文
  • Organizer: 第15回 ウイルス学キャンプ
  • Invited
• [Presentation] 好中球由来 miR-223 の発現抑制は皮膚感染創における黄色ブドウ球菌排除を促進する (2018)
  • Author(s): 森亮一
  • Organizer: 第41回日本分子生物学会年会
• [Presentation] 健診成績から要介護リスクを予測するリスクスコア計算システムの構築 (2018)
  • Author(s): 田邊直仁、百都健、丹野高三、原田亜紀子、木下裕貴、伊藤俊貴、大橋靖雄、上島弘嗣
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 血清尿酸値の変化率と慢性腎臓病の新規発症 : J-MICC Study大幸地区 (2018)
  • Author(s): 藤井亮輔, 近藤高明, 菱田朝陽, 大西丈二, 内藤真理子, 浜島信之, 若井建志
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 化学療法レジメン管理の後方視研究 (2018)
  • Author(s): 高野 淳, 住本秀敏, 寺本晃治, 醍醐弥太郎
  • Organizer: 第115回日本内科学会講演会
• [Presentation] 黄色ブドウ球菌感染創における C/EBPα-miR-223-IL6 分泌経路の機能解析 (2018)
  • Author(s): 森亮一
  • Organizer: 第107回日本病理学会総会
• [Presentation] 一般住民を対象としたビタミンE摂取量とABCA1遺伝子DNAメチル化率との関連 (2018)
  • Author(s): 鈴木康司、山田宏哉、藤井亮輔、坪井良樹、前田圭介、萩原 千晴、橋本修二、浜島信之
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 一般住民を対象としたBDNF遺伝子DNAメチル化率と認知機能との関連 (2018)
  • Author(s): 萩原 千晴、山田宏哉、藤井亮輔、近藤真理、前田圭介、橋本修二、浜島信之、鈴木康司
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 一般住民における野菜・果物類摂取頻度と白血球中TXNIP遺伝子のDNAメチル化率との関連 (2018)
  • Author(s): 前田圭介、山田宏哉、藤井亮輔、坪井良樹、萩原千晴、橋本修二、浜島信之、鈴木康司
  • Organizer: 第77回日本公衆衛生学会総会
• [Presentation] 遺伝子異常からコルチゾール産生副腎腫瘍の病態に迫る (2018)
  • Author(s): 鈴木佐和子
  • Organizer: 第28回臨床内分泌代謝update
  • Invited
• [Presentation] ビロールイミダゾールポリアミドによるがん治療の評価 : Chem-seq (2018)
  • Author(s): Lin Jason, 平岡桐子, Sakthisri Krishnamurthy, 井上貴博, 養田裕行, 篠崎喜脩, 渡部隆義, 高取敦志, 越川信子, 永瀬浩喜
  • Organizer: 第77回日本癌学会学術総会
  • Int'l Joint Research
• [Presentation] ゲノム解析によるピロールイミダゾールポリアミドで生化学的機能および臨床的副作用の予測 (2018)
  • Author(s): Lin Jason, 平岡桐子, 養田裕行, Sakthisri Krishnamurthy, 篠崎喜脩, 渡部隆義, 高取敦志, 越川信子, Horton Paul, 永瀬浩喜
  • Organizer: 第27回日本癌病態治療研究会
• [Presentation] ゲノムシークエンス時代における 成人T細胞白血病・リンパ腫の病態研究 (2018)
  • Author(s): 内丸薫
  • Organizer: 第77回日本癌学会学術総会
  • Invited
• [Presentation] がん抑制因子から促進因子に変換するEphA2プロセシングの解明 (2018)
  • Author(s): 越川直彦
  • Organizer: がん抑制因子から促進因子に変換するEphA2プロセシングの解明 シンボジウム
  • Invited
• [Presentation] オーダメイド食事指導に向けたHDL-Cに関わるSNPのシステマティックレビュー (2018)
  • Author(s): 秋元 柊, 川田久美子, 中野夏菜, 坂下友理, 遠藤 香, 栗木清典
  • Organizer: 第7回日本栄養改善学会東海支部会学術総会
• [Presentation] ウイルスと宿主を標的としたクリニカルシーケンス技術の開発 (2018)
  • Author(s): 山岸誠
  • Organizer: 第77回日本癌学会学術総会
  • Invited
• [Presentation] アルツハイマー病危険因子APOEの長寿に対する効果 (2018)
  • Author(s): 篠原 充
  • Organizer: 第7回 大阪大学神経難病フォーラム
• [Presentation] アヂポネクチン濃度、遺伝子多型と食事の関連についてのシステマティックレピュー (2018)
  • Author(s): 可児美月, 野神さくら、嶌 美幸, 川田久美子, 中野夏菜, 秋元 柊, 坂下友理, 遠藤 香, 栗木清典
  • Organizer: 第7回日本栄養改善学会東海支部会学術総会
• [Presentation] Weight gain in adulthood and parental hypertension as the risk of hypertension : from the J-MICC Study (2018)
  • Author(s): Okada R, Naito M, Maruyama K, Tsukamoto M, Sasakabe T, Tamura T, Kawai S, Hishida A, Wakai K, J-MICC Study Group
  • Organizer: The 27th Scientific Meeting of the International Society of Hypertension
  • Int'l Joint Research
• [Presentation] u, “Functional importance of JAK-STAT pathways in HTLV-1 infected cells” (2018)
  • Author(s): Izumi Ishizaki, Makoto Yamagishi, Haruna Shiga, Atae Utsunomiya, Yuetsu Tanaka, Toshiki Watanabe, Kaor Ucimaruiar
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] Tau-induced neuroinflammation in early Alzheimer's disease (2018)
  • Author(s): 寺田達弘、小尾智一、横倉正倫、武内智康、島田斉、須原哲也、樋口真人、松平敬史、尾内康臣
  • Organizer: 第58回日本核医学学会学術総会
• [Presentation] Targeting miR-223 in neutrophils enhances the clearance of S. Aureus in infected wounds (2018)
  • Author(s): 森亮一
  • Organizer: 東京理科大学トランスレーショナルリサーチセンター・ハワイ大学 合同シンポジウム
• [Presentation] Target therapy for ALS with RNA aptamers -rescue of ALS phenotype resulting from loss of motor neurons with TDP-43 pathology in ALS model mice. (2018)
  • Author(s): Akamatsu M, Yamashita T, Teramoto S, Huang, Z, Niu L, Kwak S
  • Organizer: The 49th Annual Meeting The Society for Neuroscience 2018
  • Int'l Joint Research
• [Presentation] Role of C/EBP α-miR-223-Interleukin-6 secretion pathway at Staphylococcus aureus-infected wound sites (2018)
  • Author(s): 森亮一
  • Organizer: 第41回日本基礎老化学会大会
• [Presentation] RNA aptamer as a potential drug candidate for ALS-rescue of clinicopathologic ALS phenotype in model mice. (2018)
  • Author(s): Akamatsu M, Yamashita T, Teramoto S, Huang, Z, Niu L, Kwak S
  • Organizer: 5th RNA Metabolism in Neurobiological Disease Conference 2018
  • Int'l Joint Research
• [Presentation] Reduced mitochondrial activity in the living brain of early-stage Alzheimer's disease (2018)
  • Author(s): 寺田 達弘, 小尾 智一, 武内 智康, 松平 敬史, 荒木 保清, 杉浦 明, 山崎 公也, 塚田 秀夫, 尾内 康臣
  • Organizer: 第59回日本神経学会学術大会
• [Presentation] Potential application of 18F-THK5351 and its derivatives for PET imaging of astrogliosis in human brain. (2018)
  • Author(s): Okamura N, Harada R, Ishiki A, Furumoto S, Arai H, Yanai K, Kudo Y.
  • Organizer: The Alzheimer's Association International Conference (AAIC) 2018
  • Int'l Joint Research
• [Presentation] OVEREXPRESSION OF GALECTIN-3 IN CANCER-ASSOCIATED FIBROBLASTS SERVES AS A PROGNOSTIC FACTOR IN INVASIVE PULMONARY ADENOCARCINOMA (2018)
  • Author(s): Yoko Kataoka, Yasuhiko Ohshio, Tomoyuki Igarashi, Koji Teramoto, Jun Hanaoka
  • Organizer: 26th Meeting of the European Society of Thoracic Surgeons
  • Int'l Joint Research
• [Presentation] Neuronal functions of ER stress sensor BBF2H7-derived small peptide fragments in neurotoxicity and fibrilization of amyloidβ (2018)
  • Author(s): 松久幸司、齋藤敦、蔡龍杰、柳田寛太、大河内正康、工藤幸司、松本雅記、中山敬一、今泉和則
  • Organizer: 第61回日本神経化学会大会・第40回日本生物学的精神医学会
• [Presentation] miR-223発現抑制は皮膚創傷部位の感染予防に効果的である (2018)
  • Author(s): 森亮一
  • Organizer: 第8回臨床ゲノム医療学会
• [Presentation] Massive single cell profiling of peripheral blood mononuclear cells from HTLV-1-infected individuals. (2018)
  • Author(s): 佐藤賢文
  • Organizer: HTLV-1合同セミナー
• [Presentation] Massive single cell profiling of peripheral blood from human T-cell leukemia virus infected individuals (2018)
  • Author(s): 佐藤賢文
  • Organizer: KAIST-KUシンポジウム
• [Presentation] Insights from biochemical analyses of regional distribution of Alzheimer's pathologies (2018)
  • Author(s): 篠原 充
  • Organizer: ICN2018 TOKYO
  • Int'l Joint Research
• [Presentation] In vivo phosphorylation of tau in brains of Marmoset, a non-human Primate (2018)
  • Author(s): Sharma, S., Shiozawa, S., Kobayashi, R., Murayama, S., Saito, T., Ando, K., Okano, H., Kimura, T., Hisanaga, S.
  • Organizer: Asian Pacific Society for Neurochemistry
  • Int'l Joint Research
• [Presentation] History of clarifying pathogenesis of neurodegenerative disease and development of neuropathology (2018)
  • Author(s): Yoshio Hashizume
  • Organizer: ICN2018
  • Int'l Joint Research / Invited
• [Presentation] Functional importance of JAK-STAT pathways in HTLV-1 infected cells (2018)
  • Author(s): Izumi Ishizaki, Makoto Yamagishi, Haruna Shiga, Atae Utsunomiya, Yuetsu Tanaka, Toshiki Watanabe, Kaoru Uchimaru
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] Comprehensive identification of wound healing and inflammation miRNAs reveals a key role for miR-223 in neutrophilic clearance of S. aureus at wound sites (2018)
  • Author(s): 森亮一
  • Organizer: EMBL Symposia The Complex Life of RNA
  • Int'l Joint Research
• [Presentation] Chem-seq : Evaluation of Genomewide Binding Effects of DNA Minor Groove-Binding Pyrrole Imidazole Polyamides (2018)
  • Author(s): Jason Lin, Atsushi Takatori, Paul Horton, Hiroki Nagase
  • Organizer: RECOMB/ISCB Conference on Regulatory & Systems Genomics with DREAN Challenges 2018
  • Int'l Joint Research
• [Presentation] APOE2 promotes longevity ; a clinical and preclinical assessment (2018)
  • Author(s): 篠原 充
  • Organizer: 第41回日本基礎老化学会大会 日韓老化学会合同シンポジウム
  • Int'l Joint Research
• [Presentation] APOE2 promotes longevity : a clinical and preclinical assessment (2018)
  • Author(s): 篠原 充
  • Organizer: 第37回日本認知症学会学術集会
• [Presentation] AMPA receptor-specific RNA aptamers rescued ALS phenotype in conditional ADAR2 knockout mice (2018)
  • Author(s): Akamatsu M, Yamashita T, Teramoto S, Huang, Z, Niu L, Kwak S
  • Organizer: The 29th International Symposium on MND/ALS
  • Int'l Joint Research
• [Presentation] ADAR2-mediated RNA editing of extracellular liner and circular RNAs ; a potential biomarker of amyotrophic lateral sclerosis. (2018)
  • Author(s): Hosaka T, Yamashita T, Teramoto S, Hirose N, Tamaoka A, Kwak S
  • Organizer: The 49th Annual Meeting The Society for Neuroscience 2018
  • Int'l Joint Research
• [Presentation] ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs (2018)
  • Author(s): Hosaka T, Yamashita T, Teramoto S, Hirose N, Tamaoka A, Kwak S
  • Organizer: 5th RNA Netabolism in Neurobiological Disease Conference 2018
  • Int'l Joint Research
• [Presentation] HEGI is a novel mucin-like membrane protein that is useful for the diagnosis of malignant mesothelioma. (2018)
  • Author(s): Hiroshima K, Miyagi Y, Tsuji S, Imai K.
  • Organizer: USCAP 2018 Annual Meeting
  • Int'l Joint Research
• [Presentation] 個別化医療とゲノム診療 (2018)
  • Author(s): 村上善則
  • Organizer: 新潟大学医歯薬学総合病院生命科学センター遺伝子医療セミナー
  • Invited
• [Presentation] ゲノム医療基礎研究成果によるオーダーメイド医療の実現へ向けた取り組み (2018)
  • Author(s): 村上善則
  • Organizer: ゲノム医療基礎研究成果によるオーダーメイド医療の実現へ向けた取り組み
  • Invited
• [Presentation] 住民健診受診者における新規高血圧発症のリスク : J-MICC Study静岡・大幸地区 (2018)
  • Author(s): 門松由佳, 内藤真理子, 丸山健太, 塚本峰子, 篠壁多恵, 川合紗世, 岡田理恵子, 田村高志, 菱田朝陽, 若井建志
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 手指の長さの比(第2指 : 第4指)と閉経の関連 (2018)
  • Author(s): 川合紗世, 内藤真理子, 丸山健太, 門松由佳, 塚本峰子, 篠壁多恵, 田村高志, 岡田理恵子, 菱田朝陽, 若井建志
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 日本人集団における全がん罹患とGGTI遺伝子多型(rs4820599)および血中γ-GTP濃度との関連 (2018)
  • Author(s): 丸山健太, 川合紗世, 内藤真理子, 門松由佳, 塚本峰子, 篠壁多恵, 田村高志, 菱田朝陽, 若井建志
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 脂質異常症と脂肪酸・炭水化物摂取の関連のKCNJ11遺伝子多型による修飾 : 縦断研究による検討 (2018)
  • Author(s): 篠壁多恵, 内藤真理子, 丸山健太, 門松由佳, 塚本峰子, 田村高志, 岡田理恵子, 川合紗世, 菱田朝陽, 若井建志
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 内臓脂肪面積とBMIに対する緑茶フラボノイド摂取量の関連における季節変動 : J-MICC Sakura Diet Study (2018)
  • Author(s): 栗木清典、遠藤香、後藤千穂
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 日常身体活動とPYCARD遺伝子メチル化の縦断的関連 (2018)
  • Author(s): 西田裕一郎、原めぐみ、桧垣靖樹、田口尚人、島ノ江千里、南里妃名子、中村和代、今泉猛、坂本龍彦、安方惇、三好伸幸、山田陽介、堀田美加子、東元健、副島英伸、新地浩一、田中恵太郎
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 就業状況と仕事ストレスの生活習慣への交互作用 : J-MICC Study 静岡・桜ヶ丘地区 (2018)
  • Author(s): 遠藤 香, 栗木清典 for Shizuoka-SakuragaokaJ-MICC Study group.
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 「エビゲノムを基盤とした新規治療戦略」PIポリアミド化合物によるエビゲノム治療薬開発への挑戦 (2018)
  • Author(s): 永瀬浩喜
  • Organizer: 第13回 日本癌分子標的治療学会トランスレーショナルリサーチ(TR)ワークショップ
• [Presentation] 化学の目でがんを考える (2018)
  • Author(s): 永瀬浩喜
  • Organizer: お茶ノ水がん学アカデミア集会
  • Invited
• [Presentation] 『これからの治療薬』ボリアミド化合物の開発 (2018)
  • Author(s): 永瀬浩喜
  • Organizer: 第3回 ミトコンドリア病研究・患者公開フォーラム
• [Presentation] 血清中の元素含有量を用いた新たながんスクリーニング法開発に関する研究～メタロバランス～ (2018)
  • Author(s): 三上 春夫
  • Organizer: 第18回千葉県立病院 学術集会
• [Presentation] 地域住民における出生体重の糖尿病関連因子への影響 (2018)
  • Author(s): 神谷真有美
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] Hclicobacter pylori感染者における萎縮性胃炎と生活習慣、DHEA-Sとの関連～J-MICC岡崎study～ (2018)
  • Author(s): 渡邉美貴
  • Organizer: 第28回日本疫学会学術総会
• [Presentation] 日本人男性における大豆食品摂取と動脈スティフネスとの関連 (2018)
  • Author(s): 上村浩一、釜野桜子、Bahari Tirani、藤岡美穂、岩崎夕貴、有澤孝吉
  • Organizer: 第28回日本疫学会総会
• [Presentation] QTL GWAS of serum anti-helicobacter pylori IgG in Japanese-data from the J-MICC Study (2018)
  • Author(s): Asahi Hishida, Masahiro Nakatochi, Sayo Kawai, Rieko Okada, Daisuke Matsui, Teruhide Koyama, Isao Watanabe, Etsuko Ozaki, Nagato Kuriyama, Yoshiyuki Watanabe, Akihiro Hosono, Miki Watanabe, Sadao Suzuki, Isao Oze, Hidemi Ito, Keitaro Matsuo, Yukihide Momo
  • Organizer: 第28回日本疫学会学術集会
• [Presentation] Interaction between genetic and environmental factors of smoking and drinking habits for HDL-C levels from GWAS. (2018)
  • Author(s): Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, Ippei Shimoshikiryo, Toshiro Takezaki, J-MICC Study Group.
  • Organizer: 第28回日本疫学会学術集会
• [Presentation] GWASメタアナリシスおよびメンデルランダム化による睡眠時間の因果パスウェイの解明 (2018)
  • Author(s): 西山毅, 中杤昌弘, 久保充明, J-MICC Study Group, JPHC Study Group, TMM Project Group
  • Organizer: 第28回日本疫学会学術集会
• [Presentation] Risk prediction model for chronic kidney disease using regularized regression methods : J-MICC Study (2018)
  • Author(s): Ryosuke Fujii, Asabi Hishida, Masahiro Nakatochi, Takaaki Kondo, Mariko Naito, Yukihide Momozawa, Michiaki Kubo, Kenji Wakai, Study Group J-MICC
  • Organizer: 第28回日本疫学会学術集会
• [Presentation] Dietary intakes of fat soluble vitamins and risk of type 2 diabetes mellitus. (2018)
  • Author(s): Ehab S. Eshak, Hiroyasu Iso, Akiko Tamakoshi
  • Organizer: American Society For Nutrition
  • Int'l Joint Research
• [Presentation] 海藻の摂取頻度と循環器疾患死亡リスクとの関連 : The JACC study (2018)
  • Author(s): 臼杵里恵, 村木功, 山岸良匡, 玉腰暁子, 磯博康
  • Organizer: 第54回日本循環器病予防学会学術集会
• [Presentation] 統合失調症脳における慢性炎症関連分子のジェネティックニューロパソロジー (2018)
  • Author(s): 和田明、國井泰人、日野瑞城、松本純弥、長岡敦子、丹羽真一、竹島明、高橋均、那波宏之、柿田明美、笠井清登、矢部博興
  • Organizer: 第13回日本統合失調症学会
• [Presentation] 精神疾患死後脳研究の最前線 (2018)
  • Author(s): 國井泰人、日野瑞城、松本純弥、長岡敦子、丹羽真一、矢部博興
  • Organizer: 第13回日本統合失調症学会
  • Invited
• [Presentation] がんの分子病態に基づいたトランスレーショナルリサーチと創薬開発 (2018)
  • Author(s): 醍醐弥太郎
  • Organizer: 第32回札幌冬季がんセミナー
  • Invited
• [Presentation] 腫瘍遺伝学の基礎 (2018)
  • Author(s): 醍醐弥太郎
  • Organizer: 第9回日本人類遺伝学会・遺伝医学セミナー入門編
  • Invited
• [Presentation] HTLV-I関連疾患撲減をめざすHTLV-I感染者コホート共同研究班(JSPFAD)の紹介 (2018)
  • Author(s): 岩永正子
  • Organizer: コホート・生体試料支援プラットフォーム市民公開講座
  • Invited
• [Presentation] Development and molecular analysis of synthetic lethality by targeting EZHI and EZH2 in T cell lymphomas (2018)
  • Author(s): Yamagishi M, Hori M, Fujikawa D, Honma D, Adachi N, Ohsugi T, Nakano K, Nakashima M, Kobayashi S, Iwanaga M, Utsunomiya A, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K
  • Organizer: 10th Annual T-Celll Lymphoma Forum
  • Int'l Joint Research
• [Presentation] EZH1/2, SWI/SNF, and MLL2 dependent heterochromatin formation and abnormal transcriptome in hematological malignancies (2018)
  • Author(s): Yamagishi Makoto, Fujikawa Dai, Hori Makoto, Honma Daisuke, Adachi Nobuaki, Kobayashi Seiichiro, Iwanaga Masako, Utsunomiya Atae, Okada Seiji, Tsukasaki Kunihiro, Tobinai Kensei, Araki Kazushi, Watanabe Toshiki, Uchimaru Kaoru
  • Organizer: 59th ASH Annual Meeting & Exposition
  • Int'l Joint Research
• [Presentation] 成人T細胞白血病・リンパ腫(ATL)の発症機構理解の進歩と発症予防・治療法開発の現状 (2018)
  • Author(s): 渡邉俊樹
  • Organizer: 平成29年度難病治療研究センター年次報告会
  • Invited
• [Presentation] 国際的視点から見たHTLV-1および関連疾患研究の現状と課題 (2018)
  • Author(s): 渡邉俊樹
  • Organizer: 平成29年度第1回長崎大学大学院セミナー
  • Invited
• [Presentation] Keynote Presentation : “Recent advances in HTLV-1 and ATL research” (2017)
  • Author(s): Watanabe T
  • Organizer: 18th International Conference on Human Retrovirology, HTLV and Related Viruses.
  • Place of Presentation: ホテルグランドアーク半蔵門(東京都港区)
  • Year and Date: 2017-03-07
  • Int'l Joint Research / Invited
• [Presentation] TTF-1/NKX2-1 : An Enigmatic Double-Edged Sword in Lung Adenocarcinoma (2017)
  • Author(s): Takahashi T
  • Organizer: The 2017 Japan-NIH joint Symposium on Advances in Biomedical Research and Disease
  • Place of Presentation: 東北大学星陵キャンパス(宮城県仙台市)
  • Year and Date: 2017-02-17
  • Invited
• [Presentation] ゲノム医療実現に向けたオーダーメイド医療の実現化プログラムの取り組みと病理組織バンキングの構築 (2017)
  • Author(s): 村上善則、湯地晃一郎、松田浩一
  • Organizer: 第11回ゲノム病理標準化センター講習会
  • Invited
• [Presentation] ゲノム医科学研究を支える基盤としてのバイオバンクジャパン (2017)
  • Author(s): 村上善則、平田真、湯地晃一郎、松田浩一
  • Organizer: 第62回日本人類遺伝学会シンポジウム「我が国のバイオバンクジャパンやコホートの現状とその将来」
  • Invited
• [Presentation] ゲノム解析に基づくがん研究と臨床応用 (2017)
  • Author(s): 村上善則
  • Organizer: ゲノム解析に基づくがん研究と臨床応用
  • Invited
• [Presentation] 若年者の睡眠特性-中高年の大規模一般集団の睡眠疫学調査との比較より (2017)
  • Author(s): 森田えみ, 内藤真理子, 若井建志, 角谷寛, 山田尚登
  • Organizer: 日本睡眠学会第42回定期学術集会
• [Presentation] 加齢による朝型化とセロトニントランスポーター遺伝子多型との関連 (2017)
  • Author(s): 森田えみ, 山田尚登, 角谷寛, 内藤真理子, 篠壁多恵, 岡田理恵子, 川合紗世, 菱田朝陽, 浜島信之, 若井建志
  • Organizer: 日本睡眠学会第42回定期学術集会
• [Presentation] Interaction between job status and psychological stress to life-style factors : the Shizuoka-Sakuragaoka J-MICC Study (2017)
  • Author(s): Endoh K, Kuriki K, J-MICC Study Gruop for Shizuoka-Sakuragaoka.
  • Organizer: The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
  • Int'l Joint Research
• [Presentation] Risk of non-alcoholic fatty liver disease and lifestyle factors : the Shizuoka-Sakuragaoka J-MICC Study (2017)
  • Author(s): Kuriki K, Endoh K, Shizuoka-Sakuragaoka J-MICC Study Group.
  • Organizer: The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
  • Int'l Joint Research
• [Presentation] Associations between body weight gain from 20 years old and family factors : the Shizuoka-Sakuragaoka J-MICC Study. (2017)
  • Author(s): Suzuki W, Wu Ren, Endoh K, Kuriki K, Shizuoka-Sakuragaoka J-MICC Study Group.
  • Organizer: The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
  • Int'l Joint Research
• [Presentation] LDL-C concentration is estimated by dietary factors with considering the genetic variation among Japanese : the J-MICC Sakura Diet Study. (2017)
  • Author(s): Akimoto S, Endoh K, Wu. Re, Suzuki W, Goto C, Kuriki K.
  • Organizer: The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
  • Int'l Joint Research
• [Presentation] Effccts of eating rate for each risk of metabolic syndrome and potential metabolic syndrome patients and the confounding factors : the Shizuoka-Sakuragaoka J-MICC Study. (2017)
  • Author(s): Wu Ren, Suzuki W, Endoh K, Kuriki K, Shizuoka-Sakuragaoka J-MICC Study Group.
  • Organizer: The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
  • Int'l Joint Research
• [Presentation] Association between four season's average of urinary sodium execration in 24-hours and salty foods in a food frequency questionnaire : the J-MICC Sakura Diet Study. (2017)
  • Author(s): Goto C, Endoh K, Kuriki K.
  • Organizer: The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
  • Int'l Joint Research
• [Presentation] 農業従事者と非従事者における高LDL-血症と野菜・果物摂取の関連 : the J-MICC Study 静岡・桜ヶ丘地区 (2017)
  • Author(s): 栗木清典、遠藤香、the J-MICC Study静岡・桜ヶ丘地区 Research Group
  • Organizer: 第64回 日本栄養改善学会学術総会