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コホート・生体試料支援プラットフォーム

Research Project

Project/Area Number 16H06277
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources

Allocation TypeSingle-year Grants
Research InstitutionThe University of Tokyo
Principal Investigator(Support) 今井 浩三  東京大学, 医科学研究所, 客員教授 (60117603)
Co-Investigator(Kenkyū-buntansha)(Support) 若井 建志  名古屋大学, 大学院医学系研究科, 教授 (50270989)
村上 善則  東京大学, 医科学研究所, 教授 (30182108)
松尾 恵太郎  愛知県がんセンター(研究所), がん予防研究分野, 分野長 (80393122)
三上 春夫  千葉県がんセンター(研究所), がん予防センター, 部長 (10332355)
鈴木 貞夫  名古屋市立大学, 大学院医学研究科, 教授 (20226509)
喜多 義邦  敦賀市立看護大学, 看護学部, 准教授 (30147524)
渡辺 能行 (渡邊 能行)  京都府立医科大学, 大学院医学研究科, 教授 (00191809)
田中 恵太郎  佐賀大学, 医学部, 教授 (50217022)
嶽崎 俊郎  鹿児島大学, 医歯学域医学系, 教授 (50227013)
栗木 清典  静岡県立大学, 食品栄養科学部, 教授 (20543705)
古庄 憲浩  九州大学, 大学院医学研究院, 准教授 (10346786)
有澤 孝吉  徳島大学, 大学院医歯薬学研究部, 教授 (30203384)
玉腰 暁子  北海道大学, 大学院医学研究院, 教授 (90236737)
今田 恒夫  山形大学, 大学院医学系研究科, 教授 (60333952)
武林 亨  慶應義塾大学, 医学部, 教授 (30265780)
三浦 克之  滋賀医科大学, 医学部, 教授 (90257452)
成松 宏人  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所・がん予防・情報学部, 部長 (50524419)
鈴木 康司  藤田保健衛生大学, 保健学研究科, 教授 (60288470)
村山 繁雄  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (50183653)
高尾 昌樹 (高雄 昌樹)  公益財団法人脳血管研究所, 美原記念病院, 研究員 (50245487)
赤津 裕康  医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員 (00399734)
齊藤 祐子  国立研究開発法人国立精神・神経医療研究センター, 病院臨床検査科, 医長 (60344066)
矢部 博興  福島県立医科大学, 医学部, 教授 (60210316)
中杤 昌弘  名古屋大学, 医学部附属病院, 病院講師 (10559983)
清水 厚志  岩手医科大学, いわて東北メディカル・メガバンク機構, 特命教授 (30327655)
醍醐 弥太郎  東京大学, 医科学研究所, 特任教授 (30345029)
高橋 隆  名古屋大学, 大学院医学系研究科, 教授 (50231395)
宮城 洋平  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所・がん分子病態学部, 総括部長 (00254194)
渡邉 俊樹  東京大学, 名誉教授 (30182934)
安井 寛  東京大学, 医科学研究所, 特任准教授 (40448593)
田中 英夫  愛知県がんセンター研究所, 疫学・予防部, 部長 (60470168)
内藤 真理子  名古屋大学, 大学院医学系研究科, 准教授 (10378010)
大中 佳三  九州大学, 医学研究院, 講師 (30325518)
森 満  札幌医科大学, 医学部, 教授 (50175634)
川崎 良  山形大学, 大学院医学系研究科, 准教授 (70301067)
Project Period (FY) 2016 – 2021
Project Status Granted (Fiscal Year 2018)
Budget Amount *help
¥2,276,040,000 (Direct Cost: ¥1,750,800,000、Indirect Cost: ¥525,240,000)
Fiscal Year 2018: ¥379,340,000 (Direct Cost: ¥291,800,000、Indirect Cost: ¥87,540,000)
Fiscal Year 2017: ¥379,340,000 (Direct Cost: ¥291,800,000、Indirect Cost: ¥87,540,000)
Fiscal Year 2016: ¥379,340,000 (Direct Cost: ¥291,800,000、Indirect Cost: ¥87,540,000)
Keywords生体試料支援 / コホート / 臨床検体 / 一般健常人 / 大規模ゲノム解析・オミックス解析 / 大規模ゲノム解析 / オミックス解析
Outline of Annual Research Achievements

①総括支援活動 : 10.1万名の健常人コホートにより、経時的生活情報とともに血清、DNA等のバイオリソースを、また、がん、脳疾患、高齢者等から、倫理面に十分配慮された、1万件に達する生体試料を、それぞれ収集してきたが、これらの研究基盤リソースを提供するとともに、これをさらに全国規模で発展継続させ、生命科学研究者の独創的な基盤的研究に貢献しようとする、この分野における我が国最大規棋の支援である。当プラットフォームの支援活動自体が国民一人ひとりとの関わりが強い活動であることから、総括支援活動においては、その支援内容や知見について広く市民の理解を得られるよう、青少年を含む一般市民に向けた公開講座を、シンポジウム等とならんで首都圏以外の各地でも積極的に開催してきた。
②一般健常人コホートを利用したバイオリソースの整備と活用支援、大規模バイオデータ解析支援、ならびに、発症情報を活用した支援として、肺腺癌の早期診断マーカー検証支援を公募・採択した。また生活習慣・健診データ(提供可能分は9.2万名)の整備、ゲノムワイド関連解析用タイピングデータとの結合を行い、提供準備を終えた。
③ブレインリソースの整備と活用支援 : 剖検で得られた死後脳をオープンリソースとした、精神・神経疾患の解明を目指した研究支援のための、日本ブレインバンクネットワークの構築と、実質的な運用の促進を行った。生前同意登録範囲を沖縄まで拡大した。さらに、国際ブレインネットワークとの連携を試みた。
④生体試料による支援活動 : 181課題に生体機能分子の高感度解析・技術支援と連携構築支援を実施。150課題にがん試料(組織、血液)を提供、8568試料を収集。論文23編に貢献。解析支援・試料支援体制を強化。普及・啓発講演を実施した。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

①総括支援活動 : これまで扱ってこなかった関東、東北、北海道などのコホートも加え、名実ともに我が国を代表するバイオリソースに育ちつつある。また、一般市民に対する公開講座等を首都圏以外の各地で積極的に開催して、国民の理解を得て進めようとしている。
②一般健常人コホートを利用したバイオリソースの整備と活用支援、大規模バイオデータ解析支援 : 本プラットフォームおよび関連学会のホームページを通じた情報発信を実施した。また増加した発症アウトカム情報を活用し、肺腺癌の早期診断マーカー検証支援を公募、審査を経て2件を採択した。さらに「がん支援活動」以来継続している10.1万名のコホートについても、第二次調査、疾病罹患・死亡調査を継続し、研究支援として生体試料、データを提供できる体制を発展させた。とくに生活習慣・健診データの整備を行い、提供の準備を終えた。
③ブレインリソースの整備と活用支援 : ブレインバンク拠点構築事業が大きく進展した。大阪大学ブレインバンクが、同大神経内科教授等の努力により構築され、生前同意登録制度、リソース保管施設の構築、主任研究者(特任教授)による神経病理診断援助などが整備されて、スタートした(既に4例の登録有り)。徳島大学神経内科では、高齢者ブレインバンクが凍結半脳の保管と固定半脳の診断援助を行なうことで、神経難病の凍結死後脳リソース構築(12例)を行った。
④生体試料による支援活動 : 支援依頼者のニーズの検討、新規の高感度分子解析技術を導入した解析支援体制の整備、生体試料バンクの国際標準化を視野に入れた収集体制の整備、ヴァーチャルスライドによる組織形態学的支援体制の強化と支援内容・成果の広報・啓発を進めつつ、支援課題数は生体機能分子解析・技術・連携支援および生体試料収集・提供支援ともに平成29年度の研究支援実施計画を上回り、国際的にインパクトのある論文・学会発表に貢献した。

Strategy for Future Research Activity

①総括支援活動 : 我が国にこれまで存在する他のコホート研究と連携して、統一された日本のコホート研究となるよう推進する。
②一般健常人コホートを利用したバイオリソースの整備と活用支援、大規模バイオデータ解析支援 : 支援件数の増加を図るため、引き続き本プラットフォームのホームページ(HP)上で、提供可能な生体試料・データ、大規模バイオデータ解析支援の情報を発信する。また関係学会に、学会HPからの上記HPへのリンクによる情報提供を依頼する。さらに、がん早期診断マーカー検証支援の継続、GWAS用タイピングデータの提供、9.2万名分の生活習慣・健診データの提供など、支援メニューの充実を図る。
③ブレインリソースの整備と活用支援 : 班長が日本神経病理学会、神経学会の要職に選任されたため、学会支援を元に、公約であるオールジャパンブレインバンクネットワーク構築と神経難病リソース構築を推進する。阪大型施設内ブレインバンク拠点、徳島大型委託保管ブレインバンク拠点を範例にして、拠点構築を拡充する。リソース利用の啓発活動を推進する。提供に関しては迅速化を図る一方、オプトアウト、リソースロケーション管理など、改訂ヒト対象医学研究倫理指針を遵守する
④生体試料による支援活動 : 多様な支援依頼者のニーズに迅速に対応してオンデマンド型の支援成果を研究者に還元するため、国際的にも先進的な分子解析支援技術のさらなる向上や新規技術の導入・強化を図り、その試料の質を国際水準以上に高めるために保存方法等を吟味し、併せて支援班内の連携、情報共有を強化し学際的共同研究の構築支援を行う。また、研究者コミュニティーや大学院教育の場でトップレベル研究者や若手向けの普及・啓発活動を積極的に展開し、支援の裾野を広げる。

Report

(2 results)
  • 2017 Annual Research Report
  • 2016 Annual Research Report

Research Products

(411 results)

All 2018 2017 2016 Other

All Int'l Joint Research Journal Article Presentation Book Remarks Patent(Industrial Property Rights)

  • [Int'l Joint Research] ハーバード大学 ダナファーバーがん研究所/シカゴ大学/NIH(アメリカ合衆国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University of Chicago/NCI/Vanderbilt University(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] University of Hong Kong/Shandong Academy of Medical Sciences/Tianjin Medical University Cancer Institute and Hospital(中国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] NHRI, Taiwan/Academia Sinica/National Yang-Ming University(台湾)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Chonnam National University, Korea/Seoul National University College of Medicine/Korea University Anam Hospital(韓国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Institute of Predictive and Personalized Medicine of Cancer(スペイン)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] National University of Singapore/Genome Institute of Singapore(シンガボール)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Correlation between thyroid stimulating hormone and the renal function of cuthyroid residents of Japan : Results from the Kyushu and Okinawa Population Study(KOPS)2018

    • Author(s)
      Tanaka Y, Furusyo N, Kato Y, Ueyama T, Yamasaki S, Murata M, Hayashi J.
    • Journal Title

      J Atheroscler Thromb

      Volume: 25 Issue: 4 Pages: 335-343

    • DOI
      10.5551/jat.41251
    • NAID
      130006602295
    • Year and Date
      2018-04-01
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autologous peripheral blood stem cell transplantation for double-refractory myeloma with <i>K-RAS</i> and <i>N-RAS</i> mutations2018

    • Author(s)
      神保光児、横山和明、小川弥穂、平野光人、越智清純、小林真之、遊佐 希、清水英悟、川俣豊隆、大野伸広、山口 類、井元清哉、古川洋一、宮野 悟、今井陽一、東條有伸.
    • Journal Title

      Jpn. J. Clin. Hematol.

      Volume: 58 Issue: 12 Pages: 2380-2385

    • DOI
      10.11406/rinketsu.58.2380
    • NAID
      130006308839
    • Year and Date
      2018-01-13
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Modification of the associations of alcohol intake with serum low-density lipoprotein cholesterol and triglycerides by ALDH2 and ADHIB polymorphisms in Japanese men2018

    • Author(s)
      Sasakabe T, Wakai K, Kawai S, Hishida A, Naito M, Suzuki S, Nindita Y, Arisawa K, Kita Y, Hara M, Kuriyama N, Hirata A, Mikami H, Oze I, Kubo M, Tanaka H, Hamajima N.
    • Journal Title

      Journal of Epidemiology

      Volume: 28 Issue: 4 Pages: 185-193

    • DOI
      10.2188/jea.JE20160189
    • NAID
      130006638863
    • Description
      in press
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A genome-wide association study in the Japanese population identifies the 12q24 locus for habftual coffee consumption : The J-MICC Study2018

    • Author(s)
      Nakagawa-Senda H, Hachiya T, Shimizu A, Hosono S, Watanabe M, Ito H, Hara M, Nishida Y, Kuriki K, Katsuura-Kamano S, Arisawa K, Nindita Y, Suzuki S, Hosono A, Mikami H, Nakamura Y, Takashima N, Nakamura Y, Kuriyama N, Wakai K, et al.
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 1493-1493

    • DOI
      10.1038/s41598-018-19914-w
    • NAID
      120006535054
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of genetic polymorphisms with erythrocyte traits : Verification of SNPs reported in a previous GWAS in a Japanese population2018

    • Author(s)
      Seiki T, Naito M, Hishida A, Takagi S, Matsunaga T, Sasakabe T, Hattori Y, Kawai S, Okada R, Yin G, Hamajima N, Wakai K.
    • Journal Title

      Gene

      Volume: 642 Pages: 172-177

    • DOI
      10.1016/j.gene.2017.11.031
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genome-wide association study identifies seven novel susceptibility loei for primary open-angle glaucoma2018

    • Author(s)
      Shiga Y, Akiyama M, Nishiguchi K M, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, Wakai K, Yoshikawa M, Miyake M, Yanaka T, et al.
    • Journal Title

      Human Molecular Genetics

      Volume: 27 Issue: 8 Pages: 1458-1467

    • DOI
      10.1093/hmg/ddy053
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.2018

    • Author(s)
      Tanikawa C, Kamatani Y, Takahashi A, Nagayama S, Mimori K, Mori M, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y, Nakamura Y, Matsuda K, et al.
    • Journal Title

      Carcinogenesis

      Volume: Epub Pages: 652-660

    • DOI
      10.1093/carcin/bgy026
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A genome-wide association study of coping behaviors suggests FBX045 is associated with emotional expression2018

    • Author(s)
      Shimanoe C, Hachiya T, Tanaka K, Sutoh Y, Shimizu A, Hishida A, Tamura T, Matsuo K, Ito H, Matsui D, Suzuki S, Watanabe M, Kuriki K, Mikami H, Nakamura Y, Momozawa Y, Kubo M, Nakatochi M, Naito M, Wakai K, et al.
    • Journal Title

      Genes, Brain and Behavior

      Volume: 印刷中

    • DOI
      10.1111/gbb.12481
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study for pollinosis identified two novel loci in interleukin (IL)-1B in a Japanese population2018

    • Author(s)
      Fujii R, Hishida A, Wu M. C, Kondo T, Hattori Y, Naito M, Endoh K, Nakatochi M, Hamajima N, Kubo M, Kuriki K, Wakai K.
    • Journal Title

      Nagoya Journal of Medical Science

      Volume: 80 Issue: 1 Pages: 109-120

    • DOI
      10.18999/nagjms.80.1.109
    • NAID
      120006410517
    • URL
      http://hdl.handle.net/2237/00027495
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Common variant of MAF/c-MAF, transcriptional factor genc in the kidney, is associated with gout susceptjbility.2018

    • Author(s)
      Toshihide Higashino, Hirotaka Matsuo, Yukinori Okada, Hiroshi Nakashima, Seiko Shimizu, Masayuki Sakiyama, Shin Tadokoro, Akiyoshi Nakayama, Makoto Kawaguchi, Mako Komatsu, Asahi Hishida, Masahiro Nakatochi, Hiroshi Ooyama, Junko Imaki, Nariyoshi Shinomiy
    • Journal Title

      Hum Cell

      Volume: 31 Pages: 10-13

    • DOI
      10.1007/s13577-017-0186-6
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations between dietary intakes of iron, copper and zinc with risk of type 2 diabetes mellitus : A large population-based prospective cohort study.2018

    • Author(s)
      Eshak ES, Iso H, Maruyama K, Muraki I, Tamakoshi A.
    • Journal Title

      Clin Nutr.

      Volume: 印刷中 Issue: 2 Pages: 667-674

    • DOI
      10.1016/j.clnu.2017.02.010
    • NAID
      120006600946
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Hcart Disease : The Japan Collaborative Cohort Study2018

    • Author(s)
      Sheerah HA, Eshak ES, Cui R, Imano H, Iso H, Tamakoshi A.
    • Journal Title

      Stroke

      Volume: 49 Issue: 2 Pages: 454-457

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The prospective association between plasma concentrations of cellular growth factors and risk of heart failure mortality in Japanese population.2018

    • Author(s)
      Ehab S Eshak, Koutatsu Maruyama, Hiroyasu Iso, Akiko Tamakoshi.
    • Journal Title

      J of Epidemiology

    • NAID
      130007607770
    • Description
      in press
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Physical activity earlier in life is inversely associated with insulin resistance among adults in Japan2018

    • Author(s)
      Fujita H. Hosono A. Shibata K. Tsujimura S. Oka K. Okamoto N. Kamiya M. Kondo F. Wakabayashi R. Ichikawa M. Yamada T. Suzuki S.
    • Journal Title

      Journal of Epidemiology

    • NAID
      130007488353
    • Description
      in press
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 地域住民の身体活動量と運動に対する自己評価2018

    • Author(s)
      藤田ひとみ、鈴木貞夫
    • Journal Title

      日本福祉大学健康科学論集

      Volume: 21 Pages: 37-43

    • NAID
      120006456092
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of birth weight with diabetes and insulin resistance among community residents2018

    • Author(s)
      Kamiya M. Hosono A. Tamai Y. Watanabe M. Shibata K. Tsujimura S. Oka K. Fujita H. Okamoto X. Kondo F. Wakabayashi R, Yamada T. Suzuki S.
    • Journal Title

      Nagoya Medical Journal

    • Description
      in press
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Does waist circumference give us any significant information rcgarding obcsity?2018

    • Author(s)
      Tsujimura S. Tamai Y. Hosono A. Shibata K. Oka K, Fujita H. Okamoto N. Kamiya M. Kondo F. Wakabayashi R. Ichikawa M. Yamada T. Suzuki S.
    • Journal Title

      Nagoya Medical Journal

    • Description
      in press
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unusual tau pathology of the cerebellum in patients with amyotrophic latoral sclerosis/parkinsonism-dementia complex from the kii peninsula, Japan.2018

    • Author(s)
      Morimoto S, Hatsuta H, Kokubo Y, Nakano Y, Hasegawa M, Yoneda M, Hirokawa Y, Kuzuhara S, Shiraishi T, Murayama S.
    • Journal Title

      Brain Pathol

      Volume: - Issue: 2 Pages: 287-291

    • DOI
      10.1111/bpa.12500
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prion-Like seeding of misfolded alpha-synuclein in the brains of dementia with lewy body patients in RT-QUIC.2018

    • Author(s)
      Sano K, Atarashi R, Satoh K, Ishibashi D, Nakagaki T, Iwasaki Y, Yoshida M, Murayama S, Mishima K, Nishida N.
    • Journal Title

      Mol Neurobiol

      Volume: - Issue: 5 Pages: 3916-3930

    • DOI
      10.1007/s12035-017-0624-1
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinicopathological characteristics of distant metastases of adenocarcinoma, squamous cell carcinoma and urothelial carcinoma : An autopsy study of older Japanese patients.2018

    • Author(s)
      Matsuda Y, Seki A, Nonaka K, Kakizaki M, Wang T, Aida J, Ishikawa N, Nakano Y, Kaneda D, Takata T, Takahashi-Fujigasaki J, Murayama S, Takubo K, Ishiwata T, Sawabe M, Arai T.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: 18 Issue: 2 Pages: 211-215

    • DOI
      10.1111/ggi.13165
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pathological and immunoblot analysis of phosphorylated TDP-43 in sporadic amyotrophic lateral sclerosis with pallido-nigro-luysian degeneration.2018

    • Author(s)
      Uchino A, Ogino M, Takahashi-Fujigasaki J, Oonuma S, Kanazawa N, Kajita S. Ichinoo M, Hasegawa M, Nishiyama K, Murayama S.
    • Journal Title

      Neuropathology

      Volume: 38 Issue: 2 Pages: 171-178

    • DOI
      10.1111/neup.12430
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optineurin pathology in the spinal cord of amyotrophic latoral sclerosis/parkinsonism-dementia complex patients in kii peninsula, Japan.2018

    • Author(s)
      Morimoto S, Hatsuta H, Motoyama R, Kokubo Y, Ishiura H, Tsuji S, Kuzubara S, Murayama S.
    • Journal Title

      Brain Pathol.

      Volume: 28 Pages: 422-426

    • DOI
      10.1111/bpa.12558
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of somatic mutations in postmortem human brains by whole gonome scquencing and their implications for psychiatric disorders.2018

    • Author(s)
      Nishioka M, Bundo M, Ueda J, Katsuoka F, Sato Y, Kuroki Y, Ishii T, Ukai W, Murayama S, Hashimoto E, Nagasaki M, Yasuda J, Kasai K, Kato T, Iwamoto K.
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 72 Issue: 4 Pages: 280-294

    • DOI
      10.1111/pcn.12632
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Intractable epilepsy due to a rosette-forming glioneuronal tumor with a dysembryoplastic neuroepithelial background.2018

    • Author(s)
      Sumitomo N, Ishiyama A, Shibuya M, Nakagawa E, Kaneko Y, Takahashi A, Otsuki T, Kakita A, Saito Y, Sato N, Sugai K, Sasaki M.
    • Journal Title

      Neuropathology

      Volume: 12

    • DOI
      10.1111/neup.12450
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Marked accumulation of oligodendroglia-like cells in temporal lobe epilcpsy with amygdala enlargement and hippocampal sclerosis.2018

    • Author(s)
      Sone D, Ikemura M, Saito Y, Taniguchi G, Kunii N.
    • Journal Title

      Neuropathology

      Volume: 38 Issue: 2 Pages: 154-158

    • DOI
      10.1111/neup.12410
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Complement activation in capillary cerebral amyloid angiopathy.2018

    • Author(s)
      Matsuo K, Shindo A, Niwa A, Tabei KI, Akatsu H, Hashizume Y, Akiyama H, Ayaki T, Maki T, Sawamoto N, Takahashi R, Oikawa S, Tomimoto H.
    • Journal Title

      Dement Geriatr Cogn Disord.

      Volume: 44 Pages: 343-343

    • DOI
      10.1159/000486091
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Targeting tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.2018

    • Author(s)
      Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H.
    • Journal Title

      Nat Commun.

      Volume: 9 Issue: 1 Pages: 433-433

    • DOI
      10.1038/s41467-018-02821-z
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] High co-expression of IL-34 and M-CSF correlates with tumor progression and poor survival in lung cancers2018

    • Author(s)
      Baghdadi M, Endo H, Takano A, Ishikawa K, Kameda Y, Wada H, Miyagi Y, Yokose T, Ito H, Nakayama H, Daigo Y, Suzuki N, Seino K
    • Journal Title

      Sci Rep

      Volume: 11;8(1) Pages: 418-418

    • DOI
      10.1038/s41598-017-18796-8
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer2018

    • Author(s)
      Daigo K, Takano A, Thang PM, Yoshitake Y, Shinohara M, Tohnai I, Murakami Y, Macgawa J, Daigo Y.
    • Journal Title

      Int J Oncol

      Volume: 52(1) Pages: 155165-155165

    • DOI
      10.3892/ijo.2017.4181
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Helicobacter pylori infection is associated with favorable outcome in advanced gastric cancer patients treated with S-1 adjuvant chemotherapy.2018

    • Author(s)
      Nishizuka SS, Tamura G, Nakatochi M, Fukushima N, Ohmori Y, Sumida C, Iwaya T, Takahashi T, Koeda K ; Northern Japan Gastric Cancer Study Consortium
    • Journal Title

      J Surg Oncol

      Volume: -

    • DOI
      10.1002/jso.24977
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Myeloma cells are activated in bone marrow microenvironment by the CD180/MD-1 complex which scnses lipopolysaccharide2018

    • Author(s)
      Kikuchi J, Kuroda Y, Koyama D, Osada N, Izumi T, Yasui H, Kawase T, Ichinohe T, Furukawa Y
    • Journal Title

      Cancer Res.

      Volume: 78 Issue: 7 Pages: 1766-1778

    • DOI
      10.1158/0008-5472.can-17-2446
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mogamulizumab (Anti-CCR4) in HTLV-1-Associated myelopathy2018

    • Author(s)
      Sato T, Coler-Reilly A, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y
    • Journal Title

      N Engl J Med

      Volume: 378(6) Pages: 529-538

    • DOI
      10.1056/nejmoa1704827
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma2018

    • Author(s)
      Kataoka K, Iwanaga M, Yasunaga J, Watanabe T, Ogawa S and et al.
    • Journal Title

      Blood

      Volume: 131 Pages: 215-225

    • DOI
      10.1182/blood-2017-01-761874
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Azacitidine effectively reduces TP53-mutant leukemic cell burden in sccondary acute myeloid leukemia after cord blood transplantation2018

    • Author(s)
      Takei T, Yokoyama K, Nakamura S, Yusa N, Shimizu E, Kasajima R, Ogawa M, Tanoue S, Konuma T, Takahashi S, Kobayashi A, Yamazaki M, Yamaguchi R, Imoto S, Miyano S, Tojo A
    • Journal Title

      Ann Hematol

      Volume: In press Pages: 1-2

    • DOI
      10.1080/10428194.2018.1443335
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Maternal undernutrition during early pregnancy inhibits postnatal growth of the tibia in the female offspring of rats by alteration of chondrogenesis.2018

    • Author(s)
      Kimura T, Hino K, Kono T, Takano A, Nitta N, Ushio N, Hino S, Takase R, Kudo M, Daigo Y, Morita W, Nakao M, Nakatsukasa M, Tamagawa T, Rafiq AM, Matsumoto A, Otani H, Udagawa J.
    • Journal Title

      Gen Comp Endocrionl.

      Volume: 260 Issue: 17 Pages: 30599-3

    • DOI
      10.1016/j.ygcen.2017.12.008
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effect of forced expression of mutated K-RAS gene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy.2017

    • Author(s)
      Matsunaga Y, Adachi Y, Sasaki Y, Koide H, Motoya M, Nosho K, Takagi H, Yamamoto H, Sasaki S, Arimura Y, Tokino T, Carbone DP, Imai K, Shinomura Y.
    • Journal Title

      Mol Careinog

      Volume: VOL. 56 Issue: 2 Pages: 515-526

    • DOI
      10.1002/mc.22513
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cancer Transitional Care for Terminally Ill Cancer Patients Can Reduce the Number of Emergency Admissions and Emergency Department Visits.2017

    • Author(s)
      Shimada N, Ishiki H, Iwase S, Chiba T, Fujiwara N, Watanabe A, Kinkawa J, Nojima M, Tojo A, Imai K.
    • Journal Title

      American Journal of Hospiec & Palliative Mcdicine

      Volume: 34 Issue: 9 Pages: 831-837

    • DOI
      10.1177/1049909116658641
    • Description
      Epub ahead of print
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer.2017

    • Author(s)
      Taniguchi H, Hoshino D, Moriya C, Zembutsu H, Nishiyama N, Yamamoto H, Kataoka K, Imai K.
    • Journal Title

      Oncotarget

      Volume: 6(28) Issue: 29 Pages: 10448-10458

    • DOI
      10.18632/oncotarget
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma.2017

    • Author(s)
      Tsuji S, Washimi K, Kageyama T, Yamashita M, Matsuura R, Yokose T, Kamada Y, Hayashi H, Morohoshi T, Tsuura Y, Yusa T, Sato T, Togayachi A, Narimatsu H, Nagasaki T, Nakamoto K, Moriwaki Y, Misawa H, Hiroshima K, Miyagi Y, Imai K.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 45768-45768

    • DOI
      10.1038/srep45768
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Inhibition of PRDM14 expression in pancrcatic cancer suppresses cancer stem-like properties and liver mctastasis in mice.2017

    • Author(s)
      Moriya C, Taniguchi H, Imai K.
    • Journal Title

      Carcinogenesis

      Volume: 38 Issue: 6 Pages: 638-648

    • DOI
      10.1093/carcin/bgx040
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Establishment of a refined culture mothod for rat colon organoids.2017

    • Author(s)
      Isshiki H, Arimura Y, Nagaishi K, Kawakami K, Onodera K, Yamashita K, Naishiro Y, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 489 Issue: 3 Pages: 305-311

    • DOI
      10.1016/j.bbrc.2017.05.142
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 日本の疾患コホートとしてのバイオバンクジャパンの取組2017

    • Author(s)
      村上善則
    • Journal Title

      実験医学

      Volume: 35 Issue: 17 Pages: 2861-2866

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes : a cross-sectional study in postmenopausal Japanese women2017

    • Author(s)
      Takagi S, Naito M, Kawai S, Okada R, Nagata C, Hosono S, Nishida Y, Takashima N, Suzuki S, Shimoshikiryo I, Mikami H, Uemura H, Kuriyama N, Ohnaka K, Kubo M, Hamajima N, Tanaka H, Wakai K.
    • Journal Title

      British Journal of Nutrition

      Volume: 118 Issue: 6 Pages: 463-472

    • DOI
      10.1017/s0007114517002239
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of six new genetic loci associated with atrial fibrillation in the Japancse population2017

    • Author(s)
      Low S-K, Takahashi A, Ebana Y, Ozaki K, Ogishima S, Yamamoto M, Satoh M, Sasaki M, Yamaji T, Iwasaki M, Tsugane S, Tanaka K, Naito M, Wakai K, Tanaka H, Furukawa T, Kubo M, Ito K, Kamatani Y, Tanaka T, et al.
    • Journal Title

      Nature Genetics

      Volume: - Issue: 6 Pages: 953-958

    • DOI
      10.1038/ng.3842
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Genetic variants of RAMP2 and CLR are associated with stroke2017

    • Author(s)
      Koyama T, Kuriyama N, Ozaki E, Matsui D, Watanabe I, Takeshita W, Iwai K, Watanabe Y, Xakatochi M, Tanaka K, Ito H, Uemura H, Katsuura-Kamano S, Kadota A, Kawai S, Sasakabe T, Okada R, Hishida A, Naito M, Kuriki K, et al.
    • Journal Title

      J Atheroscler Thromb

      Volume: 24 Issue: 12 Pages: 1267-1281

    • DOI
      10.5551/jat.41517
    • NAID
      130006235289
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Actual daily intakes of tea catechins and their estimation according to four season 3 day weighed dietary records and a short food frequency questionnaire among Japanese men and women.2017

    • Author(s)
      Endoh K, Matsui Y, Takeshita M, Katashima, Yasunaga, Kuriki K.
    • Journal Title

      Asian Pac J Cancer Prev

      Volume: 18 Issue: 10 Pages: 2875-2881

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Interactions between inflammatory gene polymorphisms and HTLV-I infection for total death, incidence of cancer, and atherosclerosis-related diseases among the Japanese population.2017

    • Author(s)
      Kairupan TS, Ibusuki R, Kheradmand M, Sagara Y, Mantjoro EM, Nindita Y, Niimura H, Kuwabara K, Ogawa S, Tsumematsu-Nakahata N, Nerome Y, Owaki T, Matsushita T, Maenohara S, Yamaguchi K, Takezaki T.
    • Journal Title

      Journal of Epidemiology

      Volume: 27 Issue: 9 Pages: 420-427

    • DOI
      10.1016/j.je.2016.08.017
    • NAID
      130006067768
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis.2017

    • Author(s)
      Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y and Nagase H.
    • Journal Title

      Gynecologic Oncology

      Volume: - Issue: 2 Pages: 377-383

    • DOI
      10.1016/j.ygyno.2016.11.045
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Association analysis identifies 65 new breast cancer risk loci2017

    • Author(s)
      Michailidou K, Lindström S, Dennis J, Beesley J, Dicks E, Keeman R, Eilber U, Qing Chen X, Fachal L, McCue K, McCart Reed AE, Ghoussaini M, Carroll JS, Jiang X, Carraecdo A, Carter BD, Castelao JE, Chan TL, David Cheng TY, Bader GD, et al.
    • Journal Title

      Nature

      Volume: 551 Issue: 7678 Pages: 92-94

    • DOI
      10.1038/nature24284
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Decrease in PSCA expression caused by helicobacter pylori infection may promote progression to severe gastritis2017

    • Author(s)
      Toyoshima O, Tanikawa C, Yamamoto R, Watanabe H, Yamashita H, Sakitani K, Yoshida S, Kubo M, Matsuo K, Ito H, Koike K, Seto Y, Matsuda K.
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 3 Pages: 3936-3945

    • DOI
      10.18632/oncotarget.23278
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cardiovascular disease prevalence and insulin resistance in the Kyushu-Okinawa population study and the framingham offspring study.2017

    • Author(s)
      Ikezaki H, Ai M, Schaefer EJ, Otokozawa S, Asztalos BF, Nakajima K, Zhou Y, Liu CT, Jacques PF, L. Cupples LA, Furusyo N.
    • Journal Title

      Journal of Clinical Lipidology

      Volume: 1 Issue: 2 Pages: 348-356

    • DOI
      10.1016/j.jacl.2017.01.014
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The relation between serum endostatin level and carotid atherosclerosis in hoalthy residents of Japan : Results from the Kyushu and Okinawa Population Study(KOPS).2017

    • Author(s)
      Kato Y, Furusyo N, Tanaka Y, Ueyama T, Yamasaki S, Murata M, Hayashi J.
    • Journal Title

      J Atheroscler Thromb

      Volume: 24 Issue: 10 Pages: 1023-1030

    • DOI
      10.5551/jat.39735
    • NAID
      130006110296
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Higher dietary cholesterol and omega-3 fatty acid intakes aro assoejatod with a lower succossful rate of Helicobacter pylori oradication therapy in Japan.2017

    • Author(s)
      Ikezaki H, Furusyo N, Jacques PF, Shimizu M, Murata M, Schaefer EJ, Urita Y, Hayashi J.
    • Journal Title

      American Journal of Clinical Nutrition

      Volume: 106 Issue: 2 Pages: 581-588

    • DOI
      10.3945/ajcn.116.144873
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Recurrent pregnancy loss and cardiovascular disease mortality in Japanese Women : A population-based, prospective cohort study.2017

    • Author(s)
      Yamada K, Iso H, Cui R, Tamakoshi A.
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 26 Pages: 1047-1054

    • DOI
      10.1016/j.jstrokecerebrovasdis.2016.12.018
    • NAID
      120006459305
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accuracy of self-reported height, weight and waist circumference in a Japanese sample2017

    • Author(s)
      Okamoto, N. Hosono, A. Shibata, K. Tsujimura, S. Oka, K. Fujita, H. Kamiya, M. Kondo, F. Wakabayashi, R. Yamada, T. Suzuki, S.
    • Journal Title

      Obesity science & practice.

      Volume: 3 Issue: 4 Pages: 417-24

    • DOI
      10.1002/osp4.122
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Excess APP O-glycosylation by GalNAc-T6 decreases Aβ production2017

    • Author(s)
      Akasaka-Manya K, Kawamura M, Tsumoto H, Saito Y, Kitazume S, Hatsuta H, Miura Y, Hisanaga S, Murayama S, Hashimoto Y, Manya H, Endo, T.
    • Journal Title

      J Biochem.

      Volume: 161 Issue: 1 Pages: 99-111

    • DOI
      10.1093/jb/mvw056
    • NAID
      40021091544
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] LRRK2 Levels and phosphorylation in Parkinson's disease brain and cases with restricted Lewy bodies.2017

    • Author(s)
      Dzamko N, Gysbers AM, Bandopadhyay R, Bolliger MF, Uchino A, Zhao Y, Takao M, Wauters S, van de Berg, WD, Takahashi-Fujigasaki J, Nichols RJ, Holton JL, Murayama S, Halliday GM.
    • Journal Title

      Mov Disord.

      Volume: 32 Issue: 3 Pages: 423-432

    • DOI
      10.1002/mds.26892
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's diseasc.2017

    • Author(s)
      Hara N, Kikuchi M, Miyashita A, Hatsuta H, Saito Y, Kasuga K, Murayama S, Ikeuchi T, Kuwano R.
    • Journal Title

      Acta Ncuropathol Commun

      Volume: 5 Issue: 1 Pages: 10-10

    • DOI
      10.1186/s40478-017-0414-z
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Simultaneous skin, nerve and muscle biopsy of neuronal intranuclear inclusion body disease.2017

    • Author(s)
      Morimoto S, Takao M, Murayama S
    • Journal Title

      J Neurol Sci.

      Volume: 372 Pages: 447-449

    • DOI
      10.1016/j.jns.2016.10.042
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for demcntia with Lowy bodies and coincident Alzheimer's disease : An autopsy-confirmed study.2017

    • Author(s)
      Morimoto S, Takao M, Hatsuta H, Nishina Y, Komiya T, Sengoku R, Nakano Y, Uchino A, Sumikura H, Saito Y, Kanemaru K, Murayama S.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 2

    • DOI
      10.1371/journal.pone.0171524
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Beta-N-methylamino-l-alanine analysis in the brains of patients with Kii ALS/PDC.2017

    • Author(s)
      Kokubo Y, Banack S. A, Morimoto S, Murayama S, Togashi T, Metcalf J. S, Cox P. A, Kuzuhara S.
    • Journal Title

      Neurology

      Volume: 89 Issue: 10 Pages: 1091-1092

    • DOI
      10.1212/wnl.0000000000004310
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Histopathology and florbetaben PET in patients incorrectly diagnosed with Alzheimer's disease.2017

    • Author(s)
      Sabbagh MN, Schauble B, Anand K, Richards D, Murayama S, Akatsu H, Takao M, Rowe CC, Masters CL, Barthel H, Gertz HJ, Peters O, Rasgon N, Jovalekic A, Sabri O, Schulz-Schaeffer WJ and Seibyl J
    • Journal Title

      J Alzheimers Dis.

      Volume: 56 Issue: 2 Pages: 441-446

    • DOI
      10.3233/jad-160821
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Beyond the midbrain atrophy : wide spectrum of structural MRI finding in cases of pathologically proven progressive supranuclear palsy.2017

    • Author(s)
      Sakurai K, Tokumaru AM, Shimoji K, Murayama S, Kanemaru K, Morimoto S, Aiba I, Nakagawa M, Ozawa Y, Shimohira M, Matsukawa N, Hashizume Y and Shibamoto Y.
    • Journal Title

      Neuroradiology.

      Volume: 印刷中 Issue: 5 Pages: 431-433

    • DOI
      10.1007/s00234-017-1812-4
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of secreted phosphoprotein 1 (osteopontin) in human sensorimotor cortex and spinal cord : Changes in patients with amyotrophic lateral sclerosis.2017

    • Author(s)
      Yamamoto T, Murayama S, Takao M, Isa T, Higo N.
    • Journal Title

      Brain Res

      Volume: 1655 Pages: 168-175

    • DOI
      10.1016/j.brainres.2016.10.030
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Technical feasibility of visualizing myenteric plexus using confocal lasor endomicroscopy.2017

    • Author(s)
      Kobayashi M, Sumiyama K, Shimojima N, Shimojima N, Ieiri S, Okano H, Kamba S, Fujimura T, Hirobe S, Kuroda T, Takahashi-Fujigasaki J.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: Epub ahead of print Issue: 9 Pages: 1604-10

    • DOI
      10.1111/jgh.13754
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] PML nuclear bodies are altered in adult-onset neuronal intranuclear hyaline inclusion disease.2017

    • Author(s)
      Nakano Y, Takahashi-Fujigasaki J. Sengoku R, Kanemaru K, -Arai T, Kanda T, Murayama S.
    • Journal Title

      J Neuropathol Exp Neurol.

      Volume: 76 Issue: 7 Pages: 585-594

    • DOI
      10.1093/jnen/nlx039
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Carbohydrate antigen 19-9- positive gastric adenocarcinoma : autopsy findings and review of the literature. Case Rep Gastroenterol. 11 3 545-553 20172017

    • Author(s)
      Wang T, Matsuda Y, Seki A, Nonaka K, Kakizaki M, Kaneda D, Takahashi-Fujigasaki J, Murayama S, Arai T.
    • Journal Title

      Case Reports in Gastroenterology

      Volume: 11 Pages: 545-553

    • DOI
      10.1159/000479223
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pathologic study of intracranial large artery atherosclerosis in 7260 autopsy cases.2017

    • Author(s)
      Kimura H, Takao M, Suzuki N, Kanemaru K, Mihara B, Murayama S.
    • Journal Title

      J Stroke Cerebrovasc Dis.

      Volume: 26 Issue: 12 Pages: 2821-2827

    • DOI
      10.1016/j.jstrokecerebrovasdis.2017.06.056
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease.2017

    • Author(s)
      Mano T, Nagata K, Nonaka T, Tarutani A, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamazaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido CT, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A, et al.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 114 Issue: 45

    • DOI
      10.1073/pnas.1707151114
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Distinct deposition of amyloid-β species in brains with Alzheimer's disease pathology visualized with MALDI imaging mass spectrometry2017

    • Author(s)
      Kakuda N, Miyasaka T, Iwasaki N, Nirasawa T, Wada-Kakuda S, Takahashi-Fujigasaki J, Murayama S, Ihara Y, Ikegawa M.
    • Journal Title

      Acta Neuropathol Commun

      Volume: 5 Issue: 1 Pages: 73-73

    • DOI
      10.1186/s40478-017-0477-x
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reduccd LRRK2 in association with retromer dysfunction in postmortem brain tissue from LRRK2 mutation carriers.2017

    • Author(s)
      Zhao Y, Perera G, Takahashi-Fujigasaki J, Mash DC, Paul J, Vonsattel G, Uchino A, Hasegawa K, Nichols RJ, Holton JL, Murayama S, Dzamko N, Halliday GM.
    • Journal Title

      Brain

      Volume: 141 Issue: 2 Pages: 486-495

    • DOI
      10.1093/brain/awx344
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 成人型エオジン好性核内封人体病の診断電子顕微鏡所見の有用性.2017

    • Author(s)
      長谷川文雄, 村山繁雄
    • Journal Title

      検査と技術

      Volume: 45 Issue: 11 Pages: 1286-1290

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Ⅳ. 神経系 1. 末梢神経. 20172017

    • Author(s)
      村山繁雄, 齊藤祐子
    • Journal Title

      病理と臨床

      Volume: 35 Pages: 61-70

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Autopsy case of C12orf65 mutation in a patient with signs of mitochondrial dysfunction.2017

    • Author(s)
      Nishihara H, Omoto M, Takao M, Higuchi Y, Koga M, Kawai M, Kawano H, Ikeda E, Takashima H, Kanda T.
    • Journal Title

      Neurology Genetics

      Volume: 3

    • DOI
      10.1212/nxg.0000000000000171
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 脳病理からみた超高齢者2017

    • Author(s)
      高尾 昌樹, 美原 盤, 新井 康通, 広瀬 信義, 三村 將
    • Journal Title

      認知神経科学

      Volume: 19 Pages: 158-63

    • NAID
      130007588598
    • Related Report
      2017 Annual Research Report
  • [Journal Article] 神経核内封入体病(NIID)の頭部MRI経時的変化2017

    • Author(s)
      伊賀崎 翔太, 芹澤 正博, 堀内 公成, 八木 宣泰, 小西 高志, 小張 昌宏, 笠原 正男, 高尾 昌樹
    • Journal Title

      臨床神経学

      Volume: 57 Pages: 791-791

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 大脳皮質基底核変性症の1剖検例2017

    • Author(s)
      八木 宣泰, 堀内 公成, 小西 高志, 今井 昇, 芹澤 正博, 笠原 正男, 高尾 昌樹, 小張 昌宏
    • Journal Title

      臨床神経学

      Volume: 57 Pages: 617-617

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Transgenic monkey model of the polyglutamine diseases recapitulating progressive nourological symptoms.2017

    • Author(s)
      Tomioka I, Ishibashi H, Motohashi HH, Takayama O, Saito Y, Nakatani T, Nogami N, Yamamoto K, Tanaka Y, Suzuki H, Kikuchi H, Aizawa S, Nagano S, Yamada D, Nishino I, Ichinohe N, Wada K, Kohsaka S, Nagai Y, Seki K, et al.
    • Journal Title

      eNeuro

      Volume: 4 Issue: 2 Pages: 0250-16

    • DOI
      10.1523/eneuro.0250-16.2017
    • NAID
      120006652066
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Estrogen-Related Factors in the frontal lobe of Alzheimer's disease patients and importance of body mass index.2017

    • Author(s)
      Honma N, Saji S, Mikami T, Yoshimura N, Mori S, Saito Y, Murayama S, Harada N
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 726-726

    • DOI
      10.1038/s41598-017-00815-3
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders2017

    • Author(s)
      Araki W, Hattori K, Kanemaru K, Yokoi Y, Omachi Y, Takano H, Sakata M, Yoshida S, Tsukamoto T, Murata M, Saito Y, Kunugi-H, Komori T, Arima K, Isbii K, Murayama S, Matsuda H, Tachimori H, Araki YM, Mizusawa H, et al.
    • Journal Title

      Biomark Res

      Volume: 5 Pages: 28-28

    • DOI
      10.1186/s40364-017-0108-5
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] MR imaging features of the cerebellum in adult-onset neuronal intranuclear inclusion disease : 8 cases.2017

    • Author(s)
      Sugiyama A, Sato N, Kimura Y, Maekawa T, Enokizono M, Saito Y, Takahashi Y, Matsuda H, Kuwabara S.
    • Journal Title

      AJNR Am J Neuroradiol.

      Volume: 38 Issue: 11 Pages: 2100-2104

    • DOI
      10.3174/ajnr.a5336
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 臨床医のための神経病理 再入門 アストログリアの病理2017

    • Author(s)
      齊藤祐子, 村山繁雄
    • Journal Title

      Clinical Neuroscience

      Volume: 35 Issue: 10 Pages: 1152-1153

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 嗜銀顆粒性認知症2017

    • Author(s)
      齊藤祐子
    • Journal Title

      内科

      Volume: 120 Issue: 2 Pages: 273-278

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Comparative analysis of cortical microinfarcts and microbleeds using 3.0-tesla postmortem magnetic resonance images and histopathology.2017

    • Author(s)
      Niwa A, Ii Y, Shindo A, Matsuo K, Ishikawa H, Taniguchi A, Takase S, Maeda M, Sakuma H, Akatsu H, Hashizume Y, Tomimoto H
    • Journal Title

      J Alzheimers Dis.

      Volume: 59 Issue: 3 Pages: 951-951

    • DOI
      10.3233/jad-161242
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Factors associated with pneumonia-caused death in older adults with autopsy-confirmed dementia.2017

    • Author(s)
      Manabe T, Mizukami K, Akatsu H, Hashizume Y, Ohkubo T, Kudo K, Hizawa N
    • Journal Title

      Intern. Med.

      Volume: 56(8) Issue: 8 Pages: 907-914

    • DOI
      10.2169/internalmedicine.56.7879
    • NAID
      130006857581
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lysophosphatidylcholine export by human ABCA7.2017

    • Author(s)
      Tomioka M, Toda Y, Manucat NB, Akatsu H, Fukumoto M, Kono N, Arai H, Kioka N, Ueda K.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 印刷中 Issue: 7 Pages: 658-665

    • DOI
      10.1016/j.bbalip.2017.03.012
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia2017

    • Author(s)
      Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Masaki N, Akatsu H, Hashizume Y, Yamamoto S, Sato S, Sasaki T, Setou M, Yabe H
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 7 Pages: 1-11

    • DOI
      10.1038/srep45050
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology.2017

    • Author(s)
      Zhang Z, Takeda-Uchimura Y, Foyez T, Ohtake-Niimi S, Narentuya, Akatsu H, Nishitsuji K, Michikawa M, Wyss-Coray T, Kadomatsu K, Uchimura K.
    • Journal Title

      Proc Nat1 Acad Sci U S A.

      Volume: 114(14) Pages: 114-114

    • DOI
      10.1073/pnas.1615036114
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics.2017

    • Author(s)
      Hirayama-Kurogi M, Takizawa Y, Kunii Y, Matsumoto J, Wada A, Hino M, Akatsu H, Hashizume Y, Yamamoto S, Kondo T, Ito S, Tachikawa M, Niwa SI, Yabe H, Terasaki T, Setou M, Ohtsuki S.
    • Journal Title

      J Proteomics.

      Volume: 158 Pages: 31-42

    • DOI
      10.1016/j.jprot.2017.02.009
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer's disease2017

    • Author(s)
      Vu HT, Akatsu H, Hashizume Y, Setou M, Ikegami K.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 40205-40205

    • DOI
      10.1038/srep40205
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A novel diagnostic marker for Alzheimer's disease2017

    • Author(s)
      アブドラ・モハンマド, 木村 成志, 赤津 裕康, 橋詰 良夫, フェルドス・タスリマ, 松原 悦朗, 道川 誠
    • Journal Title

      Dementia Japan

      Volume: 31 Issue: 4 Pages: 612-612

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] ヒト, マウス組織におけるABCA1, ABCA7蛋白の作用機構の解析2017

    • Author(s)
      戸田好信、赤津裕康、植田和光
    • Journal Title

      臨床病理

      Volume: 65 Pages: 183-183

    • Related Report
      2017 Annual Research Report
  • [Journal Article] LC-MS/MSを用いたヒト脳脊髄液中におけるアルツハイマー病の新規バイオマーカー探索2017

    • Author(s)
      野田巧、六車宜央、筒井陽仁、赤津裕康、井之上浩一
    • Journal Title

      JSBMS Letters.

      Volume: 42 Pages: 76-76

    • Related Report
      2017 Annual Research Report
  • [Journal Article] LC-HR/MSによるアルツハイマー病患者脳脊髄液のキラルメタボロミクス2017

    • Author(s)
      高山卓大、水野初、井之上浩一、赤津裕康、豊岡利正、轟木堅一郎
    • Journal Title

      JSBMS Letters

      Volume: 42 Pages: 106-106

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 高精度キラルメタボロミクスの開発とアルツハイマー患者分析への応用2017

    • Author(s)
      高山卓大、水野初、豊岡利正、井之上浩一、赤津裕康、轟木堅一郎
    • Journal Title

      JSBMS Letters

      Volume: 42 Issue: 2 Pages: 39-40

    • Related Report
      2017 Annual Research Report
  • [Journal Article] High-specd and scalable whole-brain imaging in rodents and primates.2017

    • Author(s)
      Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Wascheck JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe
    • Journal Title

      Neuron

      Volume: 94 Issue: 6 Pages: 1085-1100

    • DOI
      10.1016/j.neuron.2017.05.017
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] PKA activation and endothelial claudin-5 breakdown in the schizophrenic prefrontal cortex2017

    • Author(s)
      Nishiura K, Ichikawa-Tomikawa N, Sugimoto K, Kunii Y, Kashiwagi K, Tanaka M, Yokoyama Y, Hino M, Sugino T, Yabe H, Takahashi H, Kakita A, Imura T, Chiba H
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 55 Pages: 93382-93391

    • DOI
      10.18632/oncotarget.21850
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predictive biomarkers and effectiveness of MUC1-targeted dendritic-cell-based vaccine in patients with refractory non-small cell lung cancer2017

    • Author(s)
      Teramoto K, Ozaki Y, Hanaoka J, Sawai S, Tezuka N, Fujino S, Daigo Y, Kontani K
    • Journal Title

      Ther Adv Med Oncol

      Volume: 9 Pages: 147-157

    • DOI
      10.1177/1758834016678375
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas2017

    • Author(s)
      Matsubara D, Soda M, Yoshimoto T, Amano Y, Sakuma Y, Yamato A, Ueno T, Kojima S, Shibano T, Hosono Y, Kawazu M, Yamashita Y, Endo S, Hagiwara K, Fukayama M, Takahashi T, Mano H, Niki T
    • Journal Title

      Cancer Sci

      Volume: 108 Issue: 9 Pages: 1888-1896

    • DOI
      10.1111/cas.13313
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adcnocarcinomas2017

    • Author(s)
      Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, Kajino T, Suzuki M, Takahashi T
    • Journal Title

      Oncogene

      Volume: 524 Issue: 26 Pages: 3740-3748

    • DOI
      10.1038/onc.2016.524
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thyroid transcription factor-1-regulated miR-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells2017

    • Author(s)
      Griesing, S, Kajino T, Tai MC, Liu Z, Nakatochi M, Shimada Y, Suzuki M, Takahashi T
    • Journal Title

      Cancer Sci

      Volume: 108 Issue: 7 Pages: 1394-1404

    • DOI
      10.1111/cas.13271
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Epidemiological and clinical features of adult T-cell leukemia-lymphoma (ATL) in Japan, 2010-2011 : a nationwide survey2017

    • Author(s)
      Nosaka K, Iwanaga M, Imaizumi Y, Ishitsuka K, Ishizawa K, Ishida Y, Amano M, Ishida T, Uike N, Utsunomiya A, Ohshima K, Kawai K, Tanaka J, Tokura Y, Tobinai K, Watanabe T, Uchimaru K, Tsukasaki K
    • Journal Title

      Cancer Sci

      Volume: 108 Pages: 2478-2486

    • DOI
      10.1111/cas.13398
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proviral features of human T Cell leukemia virus type I in carriors with indeterminate western blot analysis results2017

    • Author(s)
      Kuramitsu M, Sekizuka T, Watanabe T, Okuma K, Hamaguchi I and et al.
    • Journal Title

      J Clin Microbiol

      Volume: 55(9) Pages: 2838-2849

    • DOI
      10.1128/jcm.00659-17
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inferring clonal structure in HTLV-1-infected individuals : towards bridging the gap bctwcen analysis and visualization2017

    • Author(s)
      Farmanbar A, Firouzi S, Makatowski W, Iwanaga M, Uchimaru K, Utsunomiya A, Watanabe T, Nakai K
    • Journal Title

      Hum Genomics

      Volume: 11 Pages: 1-15

    • DOI
      10.1186/s40246-017-0112-8
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Clonality of HTLV-1-infected T cells as a risk indicator for development and progression of adult T-cell leukemia2017

    • Author(s)
      Firouzi S, Farmanbar A, Nakai K, Iwanaga M, Uchimaru K, Utsunomiya A, Suzuki Y, Watanabe T
    • Journal Title

      Blood Advance

      Volume: 1 Pages: 1195-1205

    • DOI
      10.1182/bloodadvances.2017005900
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of the sensitivity and specificity performance of the Elecsys® HTLV-I/II assay in a multicenter study in Europe and Japan2017

    • Author(s)
      Laperche S, Sauleda S, Piron M, Muhlbacher A, Schennach H, Schottstedt V, Queiros L, Uno N, Yanagihara K, Imdahl R, Hey A, Klinkicht M, Melchior W, Muench P, Watanabe T.
    • Journal Title

      J Clin Microbiol

      Volume: 55 Pages: 2180-2187

    • DOI
      10.1128/jcm.00169-17
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cancor progression by reprogrammed BCAA metabolism in myeloid leukemia2017

    • Author(s)
      Hattori A, Tsunoda M, Konuma T, Kobayashi M, Nagy T, McSkimming D, Beattie N, Kannan N, Tojo A, Edison A, Ito T
    • Journal Title

      Nature

      Volume: 545 Pages: 500-504

    • DOI
      10.1038/nature22314
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Different clonal dynamics of chronic myeloid leukaemia betwecn bone marrow and the central nervous system2017

    • Author(s)
      Ogawa M, Yokoyama K, Hirano M, Jimbo K, Ochi K, Kawamata T, Ohno N, Shimizu E, Yokoyama N, Yamaguchi R, Imoto S, Uchimaru K, Takahashi N, Miyano S, Imai Y, Tojo A
    • Journal Title

      Br J Haematol

      Volume: -

    • DOI
      10.1111/bjh.15065
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The mechanism of de novo expression of programmed cell death-ligand 1 in squamous cell carcinoma of the lung2017

    • Author(s)
      Tomoyuki Igarashi, Koji Teramoto, Mitsuaki Ishida, Jun Hanaoka, Yataro Daigo
    • Journal Title

      Oncology Reports

      Volume: 38 Issue: 4 Pages: 2189-2196

    • DOI
      10.3892/or.2017.5876
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Quantitative analysis and clonal characterization of T-cell receptor β repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine.2017

    • Author(s)
      Mai T, Takano A, Suzuki H, Hirose T, Mori T, Teramoto K, Kiyotani K, Nakamura Y, Daigo Y.
    • Journal Title

      Oncol Lett.

      Volume: 14(1) Issue: 1 Pages: 283-292

    • DOI
      10.3892/ol.2017.6125
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes2017

    • Author(s)
      Nakayama A, Nakaoka H, Yamamoto K, Sakiyama M, Shaukat A, Toyoda Y, Okada Y, Kamatani Y, Nakamura T. Takada T, Inoue K, Yasujima T, Yuasa H, Shirahama Y, Wakai K. Kubo M. Matsuo H.
    • Journal Title

      Ann Rheum Dis

      Volume: 76 Pages: 869-877

    • DOI
      10.1136/annrheumdis-2016-209632
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer2017

    • Author(s)
      Okada R, Naito M, Hattori Y, Seiki T, Wakai K, Nanri H, Watanabe M, Suzuki S, Kairupan T, Takashima N, Mikami H, Ohnaka K, Watanabe Y, Katsuura-Kamano S, Kubo M, Hamajima N, Tanaka H, The J-MICC Study Group.
    • Journal Title

      Gastric Cancer

      Volume: ahead of print Pages: 246-253

    • DOI
      10.1007/s10120-016-0608-2
    • NAID
      40021129395
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Comparison of weighed food record procedures for the reference methods in two validation studies of food frequency questionnaires.2017

    • Author(s)
      Ishii Y, Ishihara J, Takachi R, Shinozawa Y, Imaeda N, Goto C, Wakai K, Takahashi T, Iso H, Nakamura K, Tanaka J, Shimazu T, Yamaji T, Sasazuki S, Sawada N, Iwasaki M, Mikami H, Kuriki K (18/33),... Tsugane S.
    • Journal Title

      Journal of Epidemiology

      Volume: - Issue: 7 Pages: 331-337

    • DOI
      10.1016/j.je.2016.08.008
    • NAID
      130005709487
    • Description
      Epub ahead of print
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree2017

    • Author(s)
      Hirokazu Uemura, A. Ammar Ghaibeh, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Tirani Bahari, Masashi Ishizu, Hiroki Moriguchi, Kokichi Arisawa
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 45502-45502

    • DOI
      10.1038/srep45502
    • NAID
      120006534987
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Interactions between Inflammatory Gene Polymorphisms and HTLV-I Infection for Total Death, Incidence of Cancer, and Atherosclerosis-Related Diseases among the Japanese Population.2017

    • Author(s)
      Kairupan TS, Ibusuki R, Kheradmand M, Sagara Y, Mantjoro EM, Nindita Y, Niimura H, Kuwabara K, Ogawa S, Tsumematsu-Nakahata N, Nerome Y, Ohwaki T, Matsushita T, Maenohara S, Yamaguchi K, Takezaki T.
    • Journal Title

      J Epidemiol

      Volume: 27

    • NAID
      130006067768
    • Description
      in press
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] No modifying effect of education level on the association between lifestyle behaviors and cardiovascular mortality : the Japan Collaborative Cohort Study2017

    • Author(s)
      Eguchi E, Iso H, Honjo K, Yatsuya H, Tamakoshi A
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 39820-39820

    • DOI
      10.1038/srep39820
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Perceived Stress and Colorectal Cancer Incidence : The Japan Collaborative Cohort Study2017

    • Author(s)
      Kikuchi N, Nishiyama T, Sawada T, Wang C, Lin Y, Watanabe Y, et al
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 40363-40363

    • DOI
      10.1038/srep40363
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm2017

    • Author(s)
      Suzuki K, Suzuki Y, Hama A, Muramatsu H, Nakatochi M, Gunji M, Ichikawa D, Hamada M, Taniguchi R, Kataoka S, Murakami N, Kojima D, Sekiya Y, Nishikawa E, Kawashima N, Narita A, Nishio N, Nakazawa Y, Iwafuchi H, Watanabe K., et. al
    • Journal Title

      Leukemia

    • DOI
      10.1038/leu.2017.101
    • Description
      Epub ahead of print
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.2017

    • Author(s)
      Seow WJ, Matsuo K, Shiraishi K, Kubo M, Daigo Y, Ito H, Sakamoto H, Kunitoh H, Tsuta K, Miyagi Y, Nakayama H, Matsumoto S, Tsuboi M, Goto K, Takahashi A, Goto A, Minamiya Y, Shimizu K, Tanaka K, Kohno T, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 26(2) Pages: 454-465

    • DOI
      10.1093/hmg/ddw414
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Adult T-cell leukemia (ATL) : molecular basis for clonal expansion and transformation of HTLV-1-infected T cells2017

    • Author(s)
      Watanabe T
    • Journal Title

      Blood

      Volume: 129 Pages: 1071-1081

    • DOI
      10.1182/blood-2016-09-692574
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Cancer stem cells in human gastrointestinal cancer.2016

    • Author(s)
      Taniguchi H, Moriya C, Igarashi H, Saitoh A, Yamamoto H, Adachi Y, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 107 Issue: 11 Pages: 1556-1562

    • DOI
      10.1111/cas.13069
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer.2016

    • Author(s)
      Kumegawa K, Maruyama R, Yamamoto E, Ashida M, Kitajima H, Tsuyada A, Niinuma T, Kai M, Yamano H, Sugai T, Tokino T, Shinomura Y, Imai K, Suzuki H.
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 26699-26699

    • DOI
      10.1038/srep26699
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway.2016

    • Author(s)
      Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, Mitsuhashi K, Igarashi H, Ito M, Tanuma T, Sukawa Y, Okita K, Hasegawa T, Imai K, Yamamoto H, Shinomura Y, Nosho K.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 11 Pages: 12704-120717

    • DOI
      10.18632/oncotarget.7260
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.2016

    • Author(s)
      Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 22 Pages: 557-566

    • DOI
      10.3748/wjg.v22.i2.557
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Seasonal allergies and serial changes of serum levels of IgG4 in cases treated with maintenance therapy for IgG4-related disease.2016

    • Author(s)
      Yamamoto M, Takahashi H, Shimizu Y, Yajima H, Suzuki C, Naishiro Y, Imai K, Shinomura Y.
    • Journal Title

      Mod Rheumatol.

      Volume: 26 Issue: 1 Pages: 161-2

    • DOI
      10.3109/14397595.2014.995893
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report.2016

    • Author(s)
      Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
    • Journal Title

      Cancer Science

      Volume: 107(3) Issue: 3 Pages: 369-371

    • DOI
      10.1111/cas.12889
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG22016

    • Author(s)
      Matsuo H, Tsunoda T, Ooyama K, Sakiyama M, Sogo T, Takada T, Nakashima A, Nakayama A, Kawaguchi M, Higashino T, Wakai K, Ooyama H, Hokari R, Suzuki H, Ichida K, Inui A, Fujimori S, Shinomiya N
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 31003-31003

    • DOI
      10.1038/srep31003
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment.2016

    • Author(s)
      Watanabe I, Kuriyama N, Miyatani F, Nomura R, Naka S, Nakano K, Ihara M, Iwai K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Tamura A, Mizuno T, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M, Tanaka T, Kanamura N, Friedland RP, Watanabe Y.
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 38561-38561

    • DOI
      10.1038/srep38561
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ethnic Differences in Glucose Homeostasis Markers between the Kyushu-Okinawa Population Study and the Framingham Offspring Study.2016

    • Author(s)
      Ikezaki H, Ai M, Schaefer EJ, Otokozawa S, Asztalos BF, Nakajima K, Zhou Y, Liu CT, Jacques PF, L. Cupples LA, Furusyo N.
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 36725-36725

    • DOI
      10.1038/srep36725
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Bowel Movement Frequency, Laxative Use, and Mortality From Coronary Heart Disease and Stroke Among Japanese Men and Women : The Japan Collaborative Cohort (JACC) Study2016

    • Author(s)
      Kubota Y, Iso H, Tamakoshi A
    • Journal Title

      Journal of Epidemiology

      Volume: 26 Issue: 5 Pages: 242-248

    • DOI
      10.2188/jea.JE20150123
    • NAID
      130005150474
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The influence of personality and perceived stress on the development of breast cancer : 20-year follow-up of 29,098 Japanese women2016

    • Author(s)
      Sawada T, Nishiyama T, Kikuchi N, Wang C, Lin Y, Mori M, et al
    • Journal Title

      Sci Rep

      Volume: 2 Pages: 32559-32559

    • DOI
      10.1038/srep32559
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Watching Television and Risk of Mortality From Pulmonary Embolism Among Japanese Men and Women : The JACC Study (Japan Collaborative Cohort)2016

    • Author(s)
      Shirakawa T, Iso H, Yamagishi K, Yatsuya H, Tanabe N, Ikehara S, et al
    • Journal Title

      Circulation

      Volume: 134 Pages: 355-357

    • DOI
      10.1161/circulationaha.116.023671
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9.2016

    • Author(s)
      Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, Okuda T, Ohara S, Murayama S, Takao M, Uchida S, Yamanaka K, Misawa H.
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 27354-27354

    • DOI
      10.1038/srep27354
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Immunolocalization of Toml in relation to protein degradation systems in Alzheimer's disease.2016

    • Author(s)
      Makioka K, Yamazaki T, Takatama M, Ikeda M, Murayama S, Okamoto K, Ikeda Y.
    • Journal Title

      J Neurol Sci.

      Volume: 365 Pages: 101-107

    • DOI
      10.1016/j.jns.2016.03.035
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans : Results from a Phase-3 Study.2016

    • Author(s)
      Seibyl J, Ishii K, Rowe CC, Leverenz JB, Ghetti B, Ironside JW, Takao M, Akatsu H, Murayama S, Bullich S, Mueller A, Koglin N, Schulz-Schaeffer WJ, Hoffmann A, Sabbagh MN, et. al
    • Journal Title

      J Nucl Med

      Volume: 57 Pages: 900-906

    • DOI
      10.2967/jnumed.115.161927
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistanttau.2016

    • Author(s)
      Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DM, Iwatsubo T, Hasegawa M.
    • Journal Title

      Acta Neuropathol.

      Volume: 131(2) Pages: 267-280

    • DOI
      10.1007/s00401-015-1503-3
    • NAID
      120006545236
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases.2016

    • Author(s)
      Kurosawa M, Matsumoto G, Sumikura H, Hatsuta H, Murayama S, Sakurai T, Shimogori T, Hattori N, Nukina N
    • Journal Title

      Neurosci Res

      Volume: 103 Pages: 64-70

    • DOI
      10.1016/j.neures.2015.08.002
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The Abundance of Nonphosphorylated Tau in Mouse and Human Tauopathy Brains Revealed by the Use of Phos-Tag Method.2016

    • Author(s)
      Kimura T, Hatsuta H, Masuda-Suzukake M, Hosokawa M, Ishiguro K, Akiyama H, Murayama S, Hasegawa M, Hisanaga S.
    • Journal Title

      Am J Pathol.

      Volume: 186 Pages: 398-409

    • DOI
      10.1016/j.ajpath.2015.10.009
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains.2016

    • Author(s)
      Kametani F, Obi T, Shishido T, Akatsu H, Murayama S, Saito Y, Yoshida M, Hasegawa M
    • Journal Title

      Scientific Reports

      Volume: - Pages: 23281-23281

    • DOI
      10.1038/srep23281
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α561.2016

    • Author(s)
      Nishimura K, Doi D, Samata B, Murayama S, Tahara T, Onoe H, Takahashi J.
    • Journal Title

      Stem Cell Reports.

      Volume: 6 Pages: 511-524

    • DOI
      10.1016/j.stemcr.2016.02.008
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Significant association of cadaveric dura mater grafting with subpial Abeta deposition and meningeal amyloid angiopathy.2016

    • Author(s)
      Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H, Yamada M
    • Journal Title

      Acta Neuropathol

      Volume: 132(2) Pages: 313-315

    • DOI
      10.1007/s00401-016-1588-3
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Histopathologic analysis of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) : a report of a new genetically confirmed case and comparison to 2 previous cases.2016

    • Author(s)
      Ito S, Takao M, Fukutake T, Hatsuta H, Funabe S, Ito N, Shimoe Y, Niki T, Nakano I, Fukayama M, Murayama S
    • Journal Title

      J Neuropath Exp Neurol

      Volume: 75 Issue: 11 Pages: 1020-1030

    • DOI
      10.1093/jnen/nlw078
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extranodal NK/T-cell lymphoma, nasal type, manifesting as rapidly progressive dementia without any mass or enhancing brain lesion.2016

    • Author(s)
      Shimatani Y, Nakano Y, Tsuyama N, Murayama S, Oki R, Miyamoto R, Murakami N, Fujita K, Watanabe S, Uehara H, Abe T, Nodera H, Kawarai T, Izumi Y, Kaji R
    • Journal Title

      Neuropathology

      Volume: 36 Pages: 456-463

    • DOI
      10.1111/neup.12285
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of variations in HLA class Ⅱ and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.2016

    • Author(s)
      Shiraishi K, Takahashi A, Takano A, Watanabe Y, Hishida T, Tsuchihara K, Miyagi Y, Tanaka K, Imai K, Minamiya Y, Sakamoto H, Inazawa J, Nakamura Y, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T, et. al.
    • Journal Title

      Nature Communications

      Volume: 7 Pages: 12451-12451

    • DOI
      10.1038/ncomms12451
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Chemotherapy-Induced IL34 Enhances Immunosuppression by Tumor-Associated Macrophages and Mediates Survival of Chemoresistant Lung Cancer Cells.2016

    • Author(s)
      Baghdadi M, Wada H, Nakanishi S, Abe H, Han N, Putra WE, Endo D, Watari H, Sakuragi N, Hida Y, Kaga K, Miyagi Y, Yokose T, Takano A, Daigo Y, Seino KI
    • Journal Title

      Cancer Res

      Volume: 76 Pages: 6030-6042

    • DOI
      10.1158/0008-5472.can-16-1170
    • NAID
      120006347198
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.2016

    • Author(s)
      Wang Z, Kohno T, Yokota J, Kunitoh H, Daigo Y, Mitsudomi T, Yatabe Y, Hida T, Iwasaki M, Shimazu T, Tsugane S, Li YJ, Yang TY, Lin CC, Yu J, Shen H, Kubo M, Chanock SJ, Rothman N, Lan Q, et. al.
    • Journal Title

      Hum Mol Genet

      Volume: 25 Pages: 620-629

    • DOI
      10.1093/hmg/ddv494
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dysregulation of c-Myb Pathway by Aberrant Expression of Proto-oncogene MYB Provides the Basis for Malignancy in Adult T-cell Leukemia/lymphoma Cells2016

    • Author(s)
      Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T.
    • Journal Title

      Clin Cancer Res.

      Volume: 22 Pages: 5915-5928

    • DOI
      10.1158/1078-0432.ccr-15-1739
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Incidence of human T-lymphotropic virus 1 infection in adolescent and adult blood donors in Japan : a nationwide retrospective cohort analysis2016

    • Author(s)
      Satake M, Iwanaga M, Sagara Y, Watanabe T, Okuma K, Hamaguchi I
    • Journal Title

      Lancet Infect Dis.

      Volume: 16 Pages: 1246-1254

    • DOI
      10.1016/s1473-3099(16)30252-3
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Polycomb-dependent epigenetic landscape in adult T-cell leukemia2016

    • Author(s)
      Fujikawa D, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Yamagishi M, Watanabe T
    • Journal Title

      Blood

      Volume: 127 Pages: 1790-1802

    • DOI
      10.1182/blood-2015-08-662593
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] HEGI is a novel mucin-like membrane protein that is useful for the diagnosis of malignant mesothelioma.2018

    • Author(s)
      Hiroshima K, Miyagi Y, Tsuji S, Imai K.
    • Organizer
      USCAP 2018 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 個別化医療とゲノム診療2018

    • Author(s)
      村上善則
    • Organizer
      新潟大学医歯薬学総合病院生命科学センター遺伝子医療セミナー
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ゲノム医療基礎研究成果によるオーダーメイド医療の実現へ向けた取り組み2018

    • Author(s)
      村上善則
    • Organizer
      ゲノム医療基礎研究成果によるオーダーメイド医療の実現へ向けた取り組み
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 住民健診受診者における新規高血圧発症のリスク : J-MICC Study静岡・大幸地区2018

    • Author(s)
      門松由佳, 内藤真理子, 丸山健太, 塚本峰子, 篠壁多恵, 川合紗世, 岡田理恵子, 田村高志, 菱田朝陽, 若井建志
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 手指の長さの比(第2指 : 第4指)と閉経の関連2018

    • Author(s)
      川合紗世, 内藤真理子, 丸山健太, 門松由佳, 塚本峰子, 篠壁多恵, 田村高志, 岡田理恵子, 菱田朝陽, 若井建志
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 日本人集団における全がん罹患とGGTI遺伝子多型(rs4820599)および血中γ-GTP濃度との関連2018

    • Author(s)
      丸山健太, 川合紗世, 内藤真理子, 門松由佳, 塚本峰子, 篠壁多恵, 田村高志, 菱田朝陽, 若井建志
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 脂質異常症と脂肪酸・炭水化物摂取の関連のKCNJ11遺伝子多型による修飾 : 縦断研究による検討2018

    • Author(s)
      篠壁多恵, 内藤真理子, 丸山健太, 門松由佳, 塚本峰子, 田村高志, 岡田理恵子, 川合紗世, 菱田朝陽, 若井建志
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 内臓脂肪面積とBMIに対する緑茶フラボノイド摂取量の関連における季節変動 : J-MICC Sakura Diet Study2018

    • Author(s)
      栗木清典、遠藤香、後藤千穂
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 日常身体活動とPYCARD遺伝子メチル化の縦断的関連2018

    • Author(s)
      西田裕一郎、原めぐみ、桧垣靖樹、田口尚人、島ノ江千里、南里妃名子、中村和代、今泉猛、坂本龍彦、安方惇、三好伸幸、山田陽介、堀田美加子、東元健、副島英伸、新地浩一、田中恵太郎
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 就業状況と仕事ストレスの生活習慣への交互作用 : J-MICC Study 静岡・桜ヶ丘地区2018

    • Author(s)
      遠藤 香, 栗木清典 for Shizuoka-SakuragaokaJ-MICC Study group.
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 「エビゲノムを基盤とした新規治療戦略」PIポリアミド化合物によるエビゲノム治療薬開発への挑戦2018

    • Author(s)
      永瀬浩喜
    • Organizer
      第13回 日本癌分子標的治療学会トランスレーショナルリサーチ(TR)ワークショップ
    • Related Report
      2017 Annual Research Report
  • [Presentation] 化学の目でがんを考える2018

    • Author(s)
      永瀬浩喜
    • Organizer
      お茶ノ水がん学アカデミア集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 『これからの治療薬』ボリアミド化合物の開発2018

    • Author(s)
      永瀬浩喜
    • Organizer
      第3回 ミトコンドリア病研究・患者公開フォーラム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 血清中の元素含有量を用いた新たながんスクリーニング法開発に関する研究~メタロバランス~2018

    • Author(s)
      三上 春夫
    • Organizer
      第18回千葉県立病院 学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 地域住民における出生体重の糖尿病関連因子への影響2018

    • Author(s)
      神谷真有美
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Hclicobacter pylori感染者における萎縮性胃炎と生活習慣、DHEA-Sとの関連~J-MICC岡崎study~2018

    • Author(s)
      渡邉美貴
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 日本人男性における大豆食品摂取と動脈スティフネスとの関連2018

    • Author(s)
      上村浩一、釜野桜子、Bahari Tirani、藤岡美穂、岩崎夕貴、有澤孝吉
    • Organizer
      第28回日本疫学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 5年間の精神ストレスとCRPの関連は、対処行動や社会的支援の変化により異なる2018

    • Author(s)
      島ノ江 千里、原 めぐみ、西田 裕一郎、南里 妃名子、安方 惇、三好信行、山田陽介、桧垣靖樹、田中 恵太郎
    • Organizer
      第88回日本衛生会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] QTL GWAS of serum anti-helicobacter pylori IgG in Japanese-data from the J-MICC Study2018

    • Author(s)
      Asahi Hishida, Masahiro Nakatochi, Sayo Kawai, Rieko Okada, Daisuke Matsui, Teruhide Koyama, Isao Watanabe, Etsuko Ozaki, Nagato Kuriyama, Yoshiyuki Watanabe, Akihiro Hosono, Miki Watanabe, Sadao Suzuki, Isao Oze, Hidemi Ito, Keitaro Matsuo, Yukihide Momo
    • Organizer
      第28回日本疫学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Interaction between genetic and environmental factors of smoking and drinking habits for HDL-C levels from GWAS.2018

    • Author(s)
      Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, Ippei Shimoshikiryo, Toshiro Takezaki, J-MICC Study Group.
    • Organizer
      第28回日本疫学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] GWASメタアナリシスおよびメンデルランダム化による睡眠時間の因果パスウェイの解明2018

    • Author(s)
      西山毅, 中杤昌弘, 久保充明, J-MICC Study Group, JPHC Study Group, TMM Project Group
    • Organizer
      第28回日本疫学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Risk prediction model for chronic kidney disease using regularized regression methods : J-MICC Study2018

    • Author(s)
      Ryosuke Fujii, Asabi Hishida, Masahiro Nakatochi, Takaaki Kondo, Mariko Naito, Yukihide Momozawa, Michiaki Kubo, Kenji Wakai, Study Group J-MICC
    • Organizer
      第28回日本疫学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Dietary intakes of fat soluble vitamins and risk of type 2 diabetes mellitus.2018

    • Author(s)
      Ehab S. Eshak, Hiroyasu Iso, Akiko Tamakoshi
    • Organizer
      American Society For Nutrition
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 海藻の摂取頻度と循環器疾患死亡リスクとの関連 : The JACC study2018

    • Author(s)
      臼杵里恵, 村木功, 山岸良匡, 玉腰暁子, 磯博康
    • Organizer
      第54回日本循環器病予防学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 統合失調症脳における慢性炎症関連分子のジェネティックニューロパソロジー2018

    • Author(s)
      和田明、國井泰人、日野瑞城、松本純弥、長岡敦子、丹羽真一、竹島明、高橋均、那波宏之、柿田明美、笠井清登、矢部博興
    • Organizer
      第13回日本統合失調症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 精神疾患死後脳研究の最前線2018

    • Author(s)
      國井泰人、日野瑞城、松本純弥、長岡敦子、丹羽真一、矢部博興
    • Organizer
      第13回日本統合失調症学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] がんの分子病態に基づいたトランスレーショナルリサーチと創薬開発2018

    • Author(s)
      醍醐弥太郎
    • Organizer
      第32回札幌冬季がんセミナー
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 腫瘍遺伝学の基礎2018

    • Author(s)
      醍醐弥太郎
    • Organizer
      第9回日本人類遺伝学会・遺伝医学セミナー入門編
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] HTLV-I関連疾患撲減をめざすHTLV-I感染者コホート共同研究班(JSPFAD)の紹介2018

    • Author(s)
      岩永正子
    • Organizer
      コホート・生体試料支援プラットフォーム市民公開講座
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Development and molecular analysis of synthetic lethality by targeting EZHI and EZH2 in T cell lymphomas2018

    • Author(s)
      Yamagishi M, Hori M, Fujikawa D, Honma D, Adachi N, Ohsugi T, Nakano K, Nakashima M, Kobayashi S, Iwanaga M, Utsunomiya A, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K
    • Organizer
      10th Annual T-Celll Lymphoma Forum
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] EZH1/2, SWI/SNF, and MLL2 dependent heterochromatin formation and abnormal transcriptome in hematological malignancies2018

    • Author(s)
      Yamagishi Makoto, Fujikawa Dai, Hori Makoto, Honma Daisuke, Adachi Nobuaki, Kobayashi Seiichiro, Iwanaga Masako, Utsunomiya Atae, Okada Seiji, Tsukasaki Kunihiro, Tobinai Kensei, Araki Kazushi, Watanabe Toshiki, Uchimaru Kaoru
    • Organizer
      59th ASH Annual Meeting & Exposition
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 成人T細胞白血病・リンパ腫(ATL)の発症機構理解の進歩と発症予防・治療法開発の現状2018

    • Author(s)
      渡邉俊樹
    • Organizer
      平成29年度難病治療研究センター年次報告会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 国際的視点から見たHTLV-1および関連疾患研究の現状と課題2018

    • Author(s)
      渡邉俊樹
    • Organizer
      平成29年度第1回長崎大学大学院セミナー
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Keynote Presentation : “Recent advances in HTLV-1 and ATL research”2017

    • Author(s)
      Watanabe T
    • Organizer
      18th International Conference on Human Retrovirology, HTLV and Related Viruses.
    • Place of Presentation
      ホテルグランドアーク半蔵門(東京都港区)
    • Year and Date
      2017-03-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] TTF-1/NKX2-1 : An Enigmatic Double-Edged Sword in Lung Adenocarcinoma2017

    • Author(s)
      Takahashi T
    • Organizer
      The 2017 Japan-NIH joint Symposium on Advances in Biomedical Research and Disease
    • Place of Presentation
      東北大学星陵キャンパス(宮城県仙台市)
    • Year and Date
      2017-02-17
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] ゲノム医療実現に向けたオーダーメイド医療の実現化プログラムの取り組みと病理組織バンキングの構築2017

    • Author(s)
      村上善則、湯地晃一郎、松田浩一
    • Organizer
      第11回ゲノム病理標準化センター講習会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ゲノム医科学研究を支える基盤としてのバイオバンクジャパン2017

    • Author(s)
      村上善則、平田真、湯地晃一郎、松田浩一
    • Organizer
      第62回日本人類遺伝学会シンポジウム「我が国のバイオバンクジャパンやコホートの現状とその将来」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ゲノム解析に基づくがん研究と臨床応用2017

    • Author(s)
      村上善則
    • Organizer
      ゲノム解析に基づくがん研究と臨床応用
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 若年者の睡眠特性-中高年の大規模一般集団の睡眠疫学調査との比較より2017

    • Author(s)
      森田えみ, 内藤真理子, 若井建志, 角谷寛, 山田尚登
    • Organizer
      日本睡眠学会第42回定期学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 加齢による朝型化とセロトニントランスポーター遺伝子多型との関連2017

    • Author(s)
      森田えみ, 山田尚登, 角谷寛, 内藤真理子, 篠壁多恵, 岡田理恵子, 川合紗世, 菱田朝陽, 浜島信之, 若井建志
    • Organizer
      日本睡眠学会第42回定期学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Interaction between job status and psychological stress to life-style factors : the Shizuoka-Sakuragaoka J-MICC Study2017

    • Author(s)
      Endoh K, Kuriki K, J-MICC Study Gruop for Shizuoka-Sakuragaoka.
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Risk of non-alcoholic fatty liver disease and lifestyle factors : the Shizuoka-Sakuragaoka J-MICC Study2017

    • Author(s)
      Kuriki K, Endoh K, Shizuoka-Sakuragaoka J-MICC Study Group.
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Associations between body weight gain from 20 years old and family factors : the Shizuoka-Sakuragaoka J-MICC Study.2017

    • Author(s)
      Suzuki W, Wu Ren, Endoh K, Kuriki K, Shizuoka-Sakuragaoka J-MICC Study Group.
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] LDL-C concentration is estimated by dietary factors with considering the genetic variation among Japanese : the J-MICC Sakura Diet Study.2017

    • Author(s)
      Akimoto S, Endoh K, Wu. Re, Suzuki W, Goto C, Kuriki K.
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effccts of eating rate for each risk of metabolic syndrome and potential metabolic syndrome patients and the confounding factors : the Shizuoka-Sakuragaoka J-MICC Study.2017

    • Author(s)
      Wu Ren, Suzuki W, Endoh K, Kuriki K, Shizuoka-Sakuragaoka J-MICC Study Group.
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Association between four season's average of urinary sodium execration in 24-hours and salty foods in a food frequency questionnaire : the J-MICC Sakura Diet Study.2017

    • Author(s)
      Goto C, Endoh K, Kuriki K.
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 農業従事者と非従事者における高LDL-血症と野菜・果物摂取の関連 : the J-MICC Study 静岡・桜ヶ丘地区2017

    • Author(s)
      栗木清典、遠藤香、the J-MICC Study静岡・桜ヶ丘地区 Research Group
    • Organizer
      第64回 日本栄養改善学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Association between objectively measured physical activity and methylation of PYCARD gene in the Japanese general population2017

    • Author(s)
      Yuichiro Nishida, Yasuki Higaki, Naoto Taguchi, Megumi Hara, Kazuyo Nakamura, Hinako Nanri, Takeshi Imaizumi, Tatsuhiko Sakamoto Mikako Horita, Koichi Shinchi, Chisato Shimanoe, Ken Higashimoto, Hidenobu Soejima, and Keitaro Tanaka
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CAVI値の経年変化に影響を与える要因に関する研究2017

    • Author(s)
      下敷領一平、指宿りえ、Yora Nindita、嶋谷圭一、桑原和代、中畑典子、新村英士、前之原茂穂、嶽崎俊郎
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 肥満及び糖代謝異常に対する間食習慣と宿主要因の相互作用に関する研究2017

    • Author(s)
      指宿りえ、Yora Nindita、下敷領一平、嶋谷圭一、桑原和代、中畑典子、前之原茂穂
    • Organizer
      第28回日本疫学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 栄養素摂取量と遺伝要因による血清LDL-C濃度の推定式の確立 : J-MICC Sakura Diet Studyの横断的検討2017

    • Author(s)
      秋元柊、遠藤香、後藤千穂、栗木清典、J-MICC Sakura Diet Study Group
    • Organizer
      第64回 日本栄養改善学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Development and validation of estimation model on LDL-C concentration according to dietary and genetic factors : the J-MICC Sakura Diet Study.2017

    • Author(s)
      Akimoto S, Endoh K, Wu. Re, Suzuki W, Goto C, Kuriki K.
    • Organizer
      The 22nd Shizuoka Forum on Health and Longevity
    • Related Report
      2017 Annual Research Report
  • [Presentation] 睡眠障害と口腔内環境の関連2017

    • Author(s)
      岩井浩明、渡邉功、山本俊郎、栗山長門、尾崎悦子、小山晃英、松井大輔、武下和久子、金村成智、渡邊能行
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ヘリコバクター・ビロリ感染者における慢性萎縮性胃炎の進展に及ぼす因子-摂取栄養素分析による検討-2017

    • Author(s)
      瀬古 千佳子
    • Organizer
      第56回日本消化器がん検診学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 抗がん剤の進歩・最新の話題2017

    • Author(s)
      永瀬浩喜
    • Organizer
      第15回 県民公開セミナー
    • Related Report
      2017 Annual Research Report
  • [Presentation] がんゲノムを標的にしたピロールイミダゾールポリアミド化合物薬物複合体2017

    • Author(s)
      永瀬浩喜、越川信子
    • Organizer
      第21回 日本がん分子標的治療学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ピロール・イミダゾール・ポリアミドによる標的ゲノム領域におけるエピジェネティクスへの容喙2017

    • Author(s)
      永瀬浩喜、高取敦志、越川信子、渡部隆義、井上貴博、クリシュナムーティ サクティシリ、Jason Lin、篠﨑喜脩
    • Organizer
      第30回モロシヌス研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 千葉県がんセンター・バイオバンクの取り組みについて2017

    • Author(s)
      巽康年、筆宝義隆、横井左奈、下里修、清宮淳、滝口伸浩、伊丹真紀子、山口武人、永瀬浩喜
    • Organizer
      第3回 クリニカルバイオバンク研究会シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 「がん」そして「癌」 : 克服と共存に向けて2017

    • Author(s)
      永瀬浩喜
    • Organizer
      大人が楽しむ科学教室 DNA科学シリーズ
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 肺癌・大腸癌における病因性mtDNA ND 遺伝子変異と転移との関連の再評価2017

    • Author(s)
      越川信子、秋元美穂、永瀬浩喜、竹永啓三
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 国民病であるがんの克服2017

    • Author(s)
      永瀬浩喜
    • Organizer
      かずさDNA研究所 開所記念講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Design of a next-generation affinity-enrichment Chem-seq sequencing procedure to assess the biochemistry of minor-groove-binding pyrrole-imidazole polyamides.2017

    • Author(s)
      J. Lin、高取敦志、平岡桐子、養田 裕行1、S. Krishnamurthy、井上貴博、渡部隆義、T. Kuo、篠崎喜脩、越川信子、P. Horton、永瀬浩喜
    • Organizer
      2017年度生命科学系学会合同年次大会 ConBio2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] がんのアキレス腱を標的にKRAS変異標的配列特異的アルキル化2017

    • Author(s)
      永瀬浩喜
    • Organizer
      第22回 がん研究会 国際がん化学療法シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 血清中の微量元素含有量を用いた新たながんスクリーニング法の開発に関する研究2017

    • Author(s)
      三上 春夫、宮城 洋平、中村 洋子、永瀬 浩喜
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 前向きコホート研究による胃がん高リスク群でのアミノ酸変化を伴う多型の解析2017

    • Author(s)
      中村洋子、滝口伸浩、三上春夫、永瀬浩喜
    • Organizer
      第26回癌病態治療研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 千葉利根川水系におけるがんの高罹患率の原因究明2017

    • Author(s)
      中村 洋子、高山 喜美子、三上 春夫、永瀬 浩喜
    • Organizer
      日本がん登録協議会 第26回学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 地域コーホート研究と千葉県のがんの地理的特性2017

    • Author(s)
      三上 春夫
    • Organizer
      第4回千葉県遺伝医療研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 壮年期における地域組織への社会参加と高血圧の関連についてJ-MICC岡崎研究2017

    • Author(s)
      野口泰司
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 腹囲はBMIと比べてHbAlcの上昇を予見するか2017

    • Author(s)
      細野晃弘
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ビロリ菌感染者における除菌治療の体重変化に与える影響2017

    • Author(s)
      玉井裕也
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 主観的な食意識が身体に及ぼす影響について-食塩に着目した検討-2017

    • Author(s)
      上島寛之
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 出生年別Helicobacter pylori(ピロリ菌)感染率の特微~J-MICC岡崎study2017

    • Author(s)
      渡邉美貴
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ピロリ菌感染、慢性胃炎とBMI, 腹囲との関連について2017

    • Author(s)
      鈴木貞夫
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 血圧脈波検査のための非肥満者腹部脂肪面積の測定意義2017

    • Author(s)
      原口 夏歩、小山 晃英、栗山 長門、尾﨑 悦子、松井 大輔、渡邉 功、田中 里佳、武下 和久子、渡邊 能行
    • Organizer
      第17回臨床血圧脈波研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 一般住民女性のサプリメント・健康食品の利用有無における実態の検討2017

    • Author(s)
      尾崎悦子、武下和久子
    • Organizer
      第64回日本栄養改善学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Amino acid replacement (K14Q) of mitochondria-derived MOTS-c affects typc 2 diabetes in men with lower physical activity2017

    • Author(s)
      Zempo H, Fuku N, Kumagai H, Nishida Y, Higaki Y, Naito H, Hara M, Tanaka K
    • Organizer
      The 3rd Congress, International Academy of Sportology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ミトコンドリアDNA由来ペブチドMOTS-cのアミノ酸置換(K14Q)は身体活動量の低い男性における2型糖尿病に関連する2017

    • Author(s)
      膳法浩史、福典之、熊谷仁、西田裕一郎、桧垣靖樹、内藤久士、原めぐみ、田中恵太郎
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] A genome-wide association study in the Japanese population identifies 12q24. 12-13 locus for habitual coffee consumption2017

    • Author(s)
      Hiroko Nakagawa, Hidemi Ito, Isao Oze, Keitaro Matsuo, Study Group J-MICC
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Rccurrent myb rearrangement in blastic plasmacytoid dendritic cell neoplasm2017

    • Author(s)
      Kyogo Suzuki, Yusuke Okuno, Yuka Suzuki, Asahito Hama, Hideki Muramatsu, Masahiro Nakatochi, Masaharu Gunji, Daisuke Ichikawa, Motoharu Hamada, Rieko Taniguchi, Shinsuke Kataoka, Norihiro Murakami, Daiei Kojima, Yuko Sekiya, Eri Nishikawa, Nozomu Kawashim
    • Organizer
      The 22nd Congress of the European Hematology Association
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Genome wide association study on pollinosis in a Japancse population : The J-MICC Study.2017

    • Author(s)
      Ryosuke FUJII, Asahi HISHIDA, Wu MC, Takaaki KONDO, Mariko NAITO, Yuta HATTORI, Masahiro NAKATOCHI, Kaori ENDOH, Kiyonori KURIKI, Nobuyuki HAMAJIMA, Kenji WAKAI
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ジャポニカアレイを活用した痛風のゲノムワイド関連解析2017

    • Author(s)
      中杤昌弘, 松尾洋孝
    • Organizer
      第2回ジャポニカアレイ研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] The association between the TLR2 gene and risk of H. pylorirelated gastric atrophy detected by SKAT.2017

    • Author(s)
      Hishida Asahi, Fujii Ryosuke, Nakatochi Masahiro, Kawai Sayo, Oze Isao, Matsuo Keitaro, Tamai Yuya, Suzuki Sadao, Kuriyama Nagato, Watanabe Yoshiyuki, Naito Mariko, Wakai Kenji
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Genome-wide association meta-analysis of usual sleep duration in 31,703 Japanese population2017

    • Author(s)
      T. Nishiyama, C. Wang, M. Nakatochi, A. Hishida, M. Naito, K. Wakai, M. Kubo, A. Goto, M. Iwasaki, A. Hozawa, M. Yamamoto, T. Hachiya, A. Shimizu, K. Tanno, M. Sasaki, S. Suzuki.
    • Organizer
      ASHG2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship of genetic and clinical factors and prevalence of CKD in a Japanese population : J-MICC Study2017

    • Author(s)
      R. Fujii, A. Hishida, M. Nakatochi, N. Furusho, H. Ikezaki, K. Tanaka, C. Shimanoe, S. Suzuki, T. Koyama, N. Kuriyama, R. Ibusuk I. Shimoshikiryo, N. Takashima, TC. Turin, K. Kuriki, K. Endoh, H. Mikami, H. Nagase, I. Oze, H. Ito, et al.
    • Organizer
      ASHG2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Possible confounding of genetic associations by alcohol consumption in GWAS meta-analysis of usual sleep duration.2017

    • Author(s)
      Takeshi Nishiyama, Chaochen Wang, Masahiro Nakatochi, Mariko Naito, Kenji Wakai, Michiaki Kubo, Atsushi Goto, Motoki Iwasaki, Atsushi Hozawa, Masayuki Yamamoto, Atsushi Shimizu, Tsuyoshi Hachiya, Kozo Tanno, Makoto Sasaki, Sadao Suzuki
    • Organizer
      日本人類遺伝学会 第62回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 家庭での受動喫煙とその後のCOPDによる死亡との関連 : JACC Study2017

    • Author(s)
      鵜川重和, 玉腰暁子, 八谷寛, 山岸良匡, 安藤昌彦, 磯博康
    • Organizer
      第69回北海道公衆衛生学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Intake of potato and mortality from cardiovascular disease in community-based population2017

    • Author(s)
      Kimura H, Yamagishi K, Muraki I, Iso H, Tamakoshi A ; for the JACC Group
    • Organizer
      Tsukuba Global Science Week 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 喫煙および禁煙年数と肺炎の死亡リスクとの関連 : The JACC study2017

    • Author(s)
      木原朋未, 山岸良匡, 磯博康, 玉腰暁子
    • Organizer
      第52回日本アルコール・アディクション医学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Epidemiology and prevention of cardiovascular disease : Experiences from CIRCS, JPHC and JACC studies2017

    • Author(s)
      Yamagishi K
    • Organizer
      The 21st International Epidemiological Assocjation (IEA) World Congress of Epidemiolgy (WCE2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Boiled bean intake and colorectal cancer incidence among Japanese : The JACC Study2017

    • Author(s)
      Itagaki T, Yamagishi K, Umesawa M, Wakai K, Watanabe Y, Iso H, Tamakoshi A
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 女性の生殖歴と循環器疾患死亡との関連 : The JACC study2017

    • Author(s)
      谷川果菜美, 磯博康, 木村尚史, 池原賢代, 玉腰暁子
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Television viewing time'and mortality from chronic kidney disease among Japanese men and women : the JACC Study2017

    • Author(s)
      Ikchara S, Iso H, Shirakawa T, Ukawa S, Tamakoshi A
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Annual report of bibank of aging research, a joint project of Tokyo metropolitan geriatric hospital and institute of gerontolog (TMGHIG) and national center of gerontology and geriatrics (NCGG).2017

    • Author(s)
      Murayama S, Sengoku R, Shibukawa M, Kanemaru K, Sato N, Yanagisawa K
    • Organizer
      Alzheimer' s Association International Conference (AAIC 2017).
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Identification of serum microRNA as a potential biomarker related to the prigression of Alzheimer's disease.2017

    • Author(s)
      Kuwano R, Hara N, Kikuchi M, Miyashita A, Hatsuta H, SaitoY, Kasuga K, Murayama S, Ikeuchi T :
    • Organizer
      Alzheimer's Association International Conference (AAIC 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Possible Human-to-Human transmission of cerebral β-Amyloidosis via cadaveric dura matter grafting.2017

    • Author(s)
      Yamada M, Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Naiki H, Sanjo M, Mizusawa H
    • Organizer
      Alzheimer's Association International Conference (AAIC 2017).
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Where are the main lesions that cause orthostatic hypotension in parkinson's disease?2017

    • Author(s)
      Sengoku R, Shibukawa M, Yamazaki M, Eguchi K, Higashihara M, Kaneda D, Nishina Y, Kanemaru K, Murayama S
    • Organizer
      21st International Congress of Parkinson's Disease and Movement Disorders. Vancouver Convention Centre
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cathecholamine levels and cardiac MIBG scintigraphy in patients with parkinson disease without and with orthostatic hypotension.2017

    • Author(s)
      Shibukawa M, Songoku R, Yamazaki M, Nishina Y, Kanemaru K, Murayama S
    • Organizer
      International Society for Autonomic Neuroscience 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The brain bank for aging research project, Tokyo, Japan.2017

    • Author(s)
      Murayama S, Sengoku R., Takada T, Matsubara T, Yamazaki M, Kobayashi M, Sakashita Y, Shibukara M, Morimoto S, Motoyama R, Hiroyoshi Y, Higashihara M, Nishina Y, Kanemaru K, Yanagisawa K, Saito Y
    • Organizer
      23th World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The color of the iris in patients with neuronal intranuclear hyaline inclusion disease will change.2017

    • Author(s)
      Sengoku R, Shibukawa M, Morimoto S, Motoyama R, Sunakawa M, Kaneda D, Nishina Y, Kanemaru K, Murayama S :
    • Organizer
      23th World Congress of Neurology.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A neuropathological report of familial Amyotrophic lateral sclerosis with an R521S FUS/TLS mutation.2017

    • Author(s)
      Takata T, Haraguchi T, Yokota O, Chiba Y, Kamada M, Deguchi K, Ueno M, Masaki T, Murayama S
    • Organizer
      23th World Congress of Neurology.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] N autopsied case with novel mutated hereditary diffuse leukoencephalopathy with spheroid (HDLS).2017

    • Author(s)
      Izumi Y, Takata T, Miyamoto R, Kawarai T, Saito Y, Murayama S, Kaji R
    • Organizer
      23th World Congress of Neurology.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Transthoracic echocardiography is useful to detect right-to-left shunt in the olderly.2017

    • Author(s)
      Motoyama R, Morimoto S, Tanaka J, Murayama S
    • Organizer
      23th World Congress of Neurology.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Validation of the simple smell identification test for evaluation of olfactory dysfunction in patients with Parkinson's diseasc.2017

    • Author(s)
      Yamazaki M, Sengoku R, Kanemaru K, Murayama S
    • Organizer
      23th World Congress of Neurology.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Enteric nervous system visualization of Hirschsprung's disease using confocal laser endomicroscopy : ex vivo human trial.2017

    • Author(s)
      Kobayashi M, Shimojima N, Kamba S, Takahashi-Fujigasaki J, Sumiyama K
    • Organizer
      DDW 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Japancse brain bank network and α-synucleinopathy ; The spread of Lewy body pathology in the peripheral autonomic nervous system.2017

    • Author(s)
      Murayama S
    • Organizer
      Scoul National University Hospital Brain Bank Symposim. Seoul, Korea, 2017.12.1
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Lewy body pathology includes olfactory cells in Parkinson's and related diseases.2017

    • Author(s)
      Murayama S
    • Organizer
      National University Hospital Brain Bank Symposim, Seoul, Korea, 2017. 12. 1
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Atheromatious Embolizationの源流を探る~大動脈血管内視鏡の挑戦~Session I 「Atheromatous Embolizationの概念は大動脈内視鏡でどう変わるか」I-I大動脈内視鏡で同定される大動脈プラークの臨床的意義2017

    • Author(s)
      村山繁雄
    • Organizer
      THE 11th TRANS CATHETER IMAGING FORUM
    • Related Report
      2017 Annual Research Report
  • [Presentation] アルツハイマー病の神経病理診断基準2017

    • Author(s)
      村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 家族性脊髓小脳変性症の家系に発生した、経過2年の進行性筋力低下を示した43歳男性剖検例2017

    • Author(s)
      小林万希子, 平田秀爾, 能重 歩, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 誤嚥性肺炎で入院し、急速な意識障害を呈し死亡したパーキンソン病の90歳女性剖検例2017

    • Author(s)
      白石朋敬, 仙石錬平, 土田真吏奈, 高田忠幸, 德丸阿耶, 金丸和富, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] RT-QuIC法陽性で孤発性クロイツフェルト・ヤコブ病(sCJDMV2K)が疑われた前頭側頭型変性症(FTLD-TDP)の一剖検例2017

    • Author(s)
      本山りえ, 中野雄太, 藤ヶ﨑純子, 仙石錬平, 石井賢二, 佐藤克也, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] RT-QuIC法陽性で孤発性クロイツフェルト・ヤコブ病(sCJDMV2K)が疑われた前頭側頭型変性症(FTLD-TDP)の一剖検例2017

    • Author(s)
      藤ヶ﨑純子, Nascimento C, Leite Renata EP, Pasqualucci Carlos A, Grinberg Lea T, Jacob-Filho W, Nagahashi M, Suely K, 和泉唯信, 山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 特発性正常圧水頭症神経病理検索システムの構築2017

    • Author(s)
      渋川茉莉, 仙石錬平, 高梨成彦, 金田大太, 藤ヶ﨑純子, 德丸阿耶, 金丸和富
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 進行性核上性麻痺の臨床画像病理関連2017

    • Author(s)
      金田大太, 高田忠幸, 中野雄太, 石井賢二, 德丸阿耶, 金丸和富, 仙石錬平, 島田 斉, 佐原成彦, 須原哲也, 藤ヶ﨑純子, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 歩行障害で発症し、進行性核上性麻痺の臨床像を呈した淡蒼球黒質ルイ体萎縮症(PNLA)の一剖検例2017

    • Author(s)
      竹内亮子, 荒木邦彦, 片多史明, 佐藤 進, 柴山秀博, 村山繁雄, 福武敏夫
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 徐々に拡大する広範脳梗塞を呈した真性多血症86歳男性剖検例2017

    • Author(s)
      中野雄太, 渋川茉莉, 小林万希子, 高田忠幸, 仙石錬平, 藤ヶ﨑純子, 金丸和富, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] EGFRチロシンキナーゼ阻害薬中止後、急速な経過で進行する粟粒性脳転移を認めた1剖検例2017

    • Author(s)
      栗原正典, 森 正也, 櫻井靖久, 佐野輝典, 齊藤祐子, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 歩行障害と認知症を呈し、病理学的に嗜銀顆粒性変化と進行性核上性麻痺様変化(PSP-like change)を認めた86歳男性解剖例2017

    • Author(s)
      金田大太, 高田忠幸, 中野雄太, 石井賢二, 德丸阿耶, 金丸和富, 仙石錬平, 藤ヶ﨑純子, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 福祉村Brain Bank 2016年次報告2017

    • Author(s)
      兼坂岳志, 小川倫弘, 赤津裕康, 谷口知恵, 山本左近, 山本孝之, 高尾昌樹, 村山繁雄, 橋詰良夫
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 美原記念病院ブレインバンクからの年次報告(2016年度)2017

    • Author(s)
      田野光敏, 田村未来, 佐藤愛海, 青柳真一, 飯島仁美, 谷津隆之, 諏訪部 桂, 木村浩晃, 高橋陽子, 相澤勝健, 赤津裕康, 村山繁雄, 高尾樹, 美原 盤, 美原恵里, 美原 樹
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 高齢者ブレインバンク年次報告2017

    • Author(s)
      村山繁雄, 仙石錬平, 小幡真希, 森島真帆, 高田忠幸, 中野雄太, 藤ヶ﨑純子, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 経過11年の時間的分散や軸索再生像を伴ったアミロイドニューロパチーの76歳男性剖検例2017

    • Author(s)
      北村明日香, 平賢一郎, 新井冨生, 池村雅子, 中村文彦, 岩田 淳, 清水 潤, 村山繁雄, 辻 省次
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] FUS/TLS遺伝子変異(R521S)を認めた筋萎縮性側索硬化症の親子剖検例の病理学的評価2017

    • Author(s)
      高田忠幸, 原口 俊, 横田 修, 鎌田正紀, 出口一志, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] MJD家系のALS剖検例2017

    • Author(s)
      平田秀爾, 能重 歩, 小林万希子, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] CSFIR新規変異を認めたhereditary diffuse leukoencephalopathy with spheoroid (HDLS)の1例2017

    • Author(s)
      和泉唯信, 高田忠幸, 宮本亮介, 瓦井俊孝, 齊藤祐子, 村山繁雄, 梶 龍兒
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 大脳皮質基底核症候群を呈し、剖検でアルツハイマー病と診断された1例2017

    • Author(s)
      山﨑幹大, 仙石錬平, 中野雄太, 德丸阿耶, 金丸和富, 村山繁雄
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 教育講演)剖検における神経・筋病理の検索法、高齢者ブレインバンクの経験より2017

    • Author(s)
      村山繁雄
    • Organizer
      第91回Neuromuscular Conference (NMC)
    • Related Report
      2017 Annual Research Report
  • [Presentation] Pathogenic mechanism on propagation of alpha-synuclein, a pathological point of view.2017

    • Author(s)
      Murayama S, Saito Y
    • Organizer
      第60回日本神経化学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 2016 annual report of Japanese brain bank for neuroscience research.2017

    • Author(s)
      Obata M, Murayama S, Takao M, Akatsu Y, Saito Y
    • Organizer
      The 40th Annual Meeting of the Japan Neuroscience Society
    • Related Report
      2017 Annual Research Report
  • [Presentation] (教育講演)ブリオン病の神経病理Update2017

    • Author(s)
      村山繁雄
    • Organizer
      第35回日本神経治療学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 「Alzheimer's disease : phenotypic variability and its molecular backgrounds」 Neuropathological variations in Alzheimer' s disease.2017

    • Author(s)
      村山繁雄
    • Organizer
      第36回日本認知症学会NINPRO-JSDR2017 Joint International Symposium
    • Related Report
      2017 Annual Research Report
  • [Presentation] 認知症を呈する白質脳症 : 画像の観点から2017

    • Author(s)
      徳丸阿耶, 櫻井圭太, 下地啓五, 亀山征史, 村山繁雄, 齊藤祐子
    • Organizer
      第36回日本認知症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 「ブレインバンク」ドナー登録者の意識-高齢遺族のグリーフケアにかかる予備的研究-2017

    • Author(s)
      小幡真希, 畠山幸子, 松原知康, 坂下泰浩, 小林万希子, 高田忠幸, 東原真奈, 仙石錬平, 仁科裕史, 広吉祐子, 森島真帆, 金丸和富, 古田光, 新井冨生, 村山繁雄
    • Organizer
      第36回日本認知症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] レビー小体病における認知機能低下とCSFバイオマーカーとの関連2017

    • Author(s)
      金丸和富, 金丸晶子, 仁科裕史, 仙石錬平, 村山繁雄
    • Organizer
      第36回日本認知症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 神経細胞特異的DNAメチローム解析によるレビー小体病の新規病態の探索2017

    • Author(s)
      土田剛行, 坂内太郎, 野間達雄, 永田健一, 山下 聡, 藤ヶ﨑純子, 村山繁雄, 西道隆臣, 牛島俊和, 辻 省次, 岩田 淳
    • Organizer
      第36回日本認知症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Creutzfeldt-Jakob disease associated with PRNP V180I-129M mutation as a cause of dementia in elderly individuals.2017

    • Author(s)
      Takao M, Kimura H, Mihara B, Kanda T, Yoshizawa K, Koide M, Arai K, Arai Y, Hirose N, Mimura M, Kitamoto T.
    • Organizer
      The 93rd Annual Meeting, American Association of Neuropathologists, Inc.,
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neuropathological study of two cases with false positive real time quakeinduced conversion result of cerebrospinal fluid for prion protein.2017

    • Author(s)
      Murayama S, Motoyama R, Shimizu S, Nakano Y, Fujigasaki J, Sengoku R, Sato K, Takao M.
    • Organizer
      The 93rd Annual Meeting, American Association of Neuropathologists, Inc.,
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Investigation of cerebral microbleeds in cases of ischemic stroke/hemorrhagic stroke using only 3.0T MRI data.2017

    • Author(s)
      Abe T, Maruyama H, Deguchi I, Mihara B, Tanahashi N, Takao M.
    • Organizer
      The XXIII World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 美原記念病院ブレインバンクからの年次報告2017

    • Author(s)
      田野光俊, 田村未来, 佐藤愛美, 青柳真一, 飯島仁美, 谷津隆之, 諏訪部桂, 木村浩晃, 高橋陽子, 相澤勝健, 赤津祐康, 村山繁雄, 高尾昌樹, 美原盤, 美原恵理, 美原樹
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] C9orf72遺伝子にリピート伸長変異を認めたFTLD-ALSの死亡時67歳男性例2017

    • Author(s)
      佐藤亮太, 尾本雅俊, 清水文崇, 吉野浩代, 高尾昌樹, 伊藤浩史, 神田隆
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 遺伝子改変技術を用いた精神・神経疾患モデル霊長類の作出と評価(S-1-3)2017

    • Author(s)
      関和彦, 富岡郁夫, 永井義隆, 齊藤祐子, 石橋英俊, 花川隆, 尾張健介, 野上尚武, 小泉昌司, 皆川栄子, 中谷輝実, 川野邊哲代
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] パーキンソン病(S-2-2)2017

    • Author(s)
      齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 過去2年のpure skinesia with gait freezingの1剖検例(0-1-AOI)2017

    • Author(s)
      関大成, 佐野輝典, 勝又淳子, 前川理沙, 日出山拓人, 岸田由紀子, 田村浩一, 齊藤祐子, 椎尾康
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 精神症状と顕著な姿勢反射障害を呈した、過去5年の進行性核上性麻痺の一解剖例(P-1-D09)2017

    • Author(s)
      佐野輝典, 川添僚也, 塚本忠, 杉山淳比古, 佐藤典子, 高橋祐二, 村田美穂, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 腫瘍様の大脳白質病変を呈し、脳生検にて皮質基底核変性症と診断した1例(P-1-D13)2017

    • Author(s)
      荒川晶, 齊藤祐子, 関大成, 光武明彦, 佐藤達哉, 勝又淳子, 前川理沙, 日出山拓人, 長谷川成人, 椎尾康
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 盗汗で発症し、治療後再発に至った中枢神経浸潤を伴うBurkitt Lymphomaの78歳男性の1解剖例(P-1-H04)2017

    • Author(s)
      永迫友規, 藤野悟央, 内尾直裕, 平賢一郎, 那須涼, 寺尾安生, 清水潤, 辻省次, 國松聡, 高橋美和子, 百瀬敏光, 池村雅子, 村山繁雄, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 意識障害が亜急性に進行し、頭部MRI上白質脳症を呈した癌性髄膜症の72歳男性例(P-1-H10)2017

    • Author(s)
      塩谷彩子, 辻浩史, 高屋敷典生, 梶有貴, 児玉泰介, 玉岡晃, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 国立精神・神経医療研究センターブレインバンク 年次報告(P-2-C10)2017

    • Author(s)
      齊藤祐子, 村山繁雄, 柿田明美, 吉田眞理, 入谷修司, 横田修, 寺田修司, 大島健一, 矢部博興, 國井泰人, 井上悠輔, 田中紀子, 村田美穂, 水澤英洋
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] サルコイド慢性ミオパチーでの筋周鞘のアルカリフォスファターゼ(ALP)陽性所見(P-2-E04)2017

    • Author(s)
      大矢寧, 若杉憲孝, 濱由香, 森まどか, 齊藤祐子, 西野一三
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 難治性てんかんの1歳11か月女児例(SS-3)2017

    • Author(s)
      平澤絢香, 本橋裕子, 須貝研司, 佐々木征行, 岩崎真樹, 中嶋英子, 福山哲広, 佐野輝典, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 改良ガリアスーブラーク簡易法のキット化の検討(TF-2-B01)2017

    • Author(s)
      國仲伸男, 佐藤裕子, 梅戸克之, 村山繁雄, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ボディアン染色に適したプロテイン銀の開発と有用性(TF-2-H04)2017

    • Author(s)
      國仲伸男, 佐藤裕子, 梅戸克之, 村山繁雄, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 皮質基底核変性症候群の経過中に暖徐に拡大する大脳白質のT2延長域を認め、生検にて皮質基底核変性症と診断した66歳女性例2017

    • Author(s)
      荒川晶, 関大成, 光部明彦, 佐藤達哉, 勝又淳子, 前川理沙, 日出山拓人, 齊藤祐子, 長谷川成人, 椎尾康 :
    • Organizer
      第221回日本神経学会関東・甲信越地方会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 日本ブレインネットの構築2017

    • Author(s)
      齊藤祐子
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Transgenic monkey model of the polyglutamine disease recapitulating progressive neurological symptoms and polyglutamine protein inclusions2017

    • Author(s)
      Nagai Y, Tomioka H, Ishibashi H, Minakawa E N, Motohasi H H, Takayama O, Saito Y, Popiel H A, Puentes S, Owari K, Nakatani T, Nogami N, Yamamoto K, Noguchi S, Nagano S, Nishino I, Ichinohe N, Wada K, Kohsaka S, Seki k
    • Organizer
      XXIII World Congress of Nourology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Histological findings of cerebral infarction treated with recombinant tissue plasminogen activator (RT-PA) : Two autopsy cases died of non-neurologic complications within a manth after RT-AP treatment2017

    • Author(s)
      Kodama S, Imafuku I, Kakuta Y, Shimizu J, Tsuji S, Murayama S, Saito Y
    • Organizer
      XXIII World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Establishment of Japan brain bank net2017

    • Author(s)
      Saito Y, Kakita A, Yoshida M, Murayama S, Iritani S, Yokota O, Terada S, Ohshima K, Yasuta K, Yabe H, Inoue Y, Tanaka N, Motoyoshi Y, Murata M, Mizusawa, H
    • Organizer
      XXIII World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Two autopsy cases of parkinson's disease with impulsive-compulsive disorders2017

    • Author(s)
      Sano T, Shioya A, Furusawa Y, Kimura Y, Sato N, Takahashi Y, Murata M, Saito Y
    • Organizer
      XXIII World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neuropathological background of autonomic dysfunction in dementia2017

    • Author(s)
      Murayama S, Saito Y
    • Organizer
      The internasional society for autonomic neuroscience 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 83 歳頃発症の認知症で、画像上、著明な脳萎縮と高度の微小出血を示した 99歳・女性2017

    • Author(s)
      橋詰良夫
    • Organizer
      第54回名古屋臨床神経病理アカデミー
    • Related Report
      2017 Annual Research Report
  • [Presentation] 球麻痺で発症し、全経過1年7か月の経過で死亡した71歳・女性2017

    • Author(s)
      橋詰良夫、横井風兒
    • Organizer
      第9回日本神経病理学会東海・北睦地方会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 成人型neuronal ceroid lipofuscinosisの剖検例2017

    • Author(s)
      橋詰良夫、兼坂岳志、小川倫弘、谷口知恵、園田尚子、赤津裕康、吉田眞理
    • Organizer
      第45回臨床神経懇話会
    • Related Report
      2017 Annual Research Report
  • [Presentation] MCIとアルツハイマー病の血液バイオ マーカーとしての補体タンパク質プロファイル2017

    • Author(s)
      劉珊、鈴木秀昭、目野浩二、赤津裕康、松川則之
    • Organizer
      第36回日本認知症学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Fmoc誘導体化LC-MS/MSを用いたヒト脳脊髄液中のアミノ酸骨格代謝系の網羅的定量分析2017

    • Author(s)
      六車宜央、筒井陽仁、赤津裕康
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 安定同位体誘導体化を基盤とする高精度キラルメタボロミクスの開発とアルツハイマー病患者CSF解析2017

    • Author(s)
      高山卓大、水野初、豊岡利正、井之上浩一、赤津裕康、轟木堅一郎
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] LC-MS/MSを用いたヒト脳脊髄液中における アルツハイマー病の新規バイオマーカー探索2017

    • Author(s)
      野田 巧、六車宜央、筒井陽仁、赤津裕康、井之上浩一
    • Organizer
      第42回日本医用マススペクトル学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] LC-HR/MSによるアルツハイマー病患者脳脊髄液のキラルメタボロミクス2017

    • Author(s)
      高山卓大、水野 初、井之上浩一、赤津裕康、豊岡利正、轟木堅一郎
    • Organizer
      第42回日本医用マススペクトル学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 認知症内患者の肺炎による死亡の検討 : システマティックレビュー&メタアナリシス2017

    • Author(s)
      間辺利江、水上勝義、赤津裕康、工藤宏一郎
    • Organizer
      第59回日本老年医学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] アルツハイマー病ヒト脳とアルツハイマー病 モデルマウス脳に置けるα1-chimaerinの発現と局在について2017

    • Author(s)
      加藤智子、小西吉裕、椎野顕彦、下濱 俊、Beach Thomas G、赤津裕康、遠山育夫
    • Organizer
      第58回日本神経病理学会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 美原記念病院ブレインバンクからの年次報告(2016年)2017

    • Author(s)
      田野光敏、田村未来、佐藤愛海、青柳真一、飯島仁美、谷津隆之、諏訪部 桂、木村浩晃、高橋陽子、相沢勝健、赤津裕康、村山繁雄、高尾昌樹、美原 盤、美原恵里、美原 樹
    • Organizer
      第58回日本神経病理学会学術研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 死後脳内において高頻度にコピー数多型(CNV)が観察された統合失調症3症例の臨床的特徴について2017

    • Author(s)
      長岡敦子、國井泰人、松本純弥、和田明、日野瑞城、丹羽真一、那波宏之、高橋 均、柿田明美、赤津裕康、橋詰良夫、山本左近、尾関祐二、矢部博興
    • Organizer
      第12回日本統合失調症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 死後脳内において高頻度にコピー数多型(CNV)が観察された統合失調症3症例の臨床的特徴について2017

    • Author(s)
      長岡敦子, 國井泰人, 松本純弥, 和田明, 日野瑞城, 丹羽真一, 那波宏之, 高橋均, 柿田明美, 赤津裕康, 橋詰良夫, 山本左近, 尾関祐二, 矢部博興
    • Organizer
      第12回日本統合失調症学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 生前登録制度に基づく精神疾患プレインバンクの実践~当事者と研究者が協働する研究体制とは~2017

    • Author(s)
      國井泰人、松本純弥、長岡敦子、日野瑞城、丹羽真一、矢部博興
    • Organizer
      第113回日本精神神経学会総会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 精神疾患死後脳研究 : ジェネティックニューロパソロジー及びリソース利用の有用性2017

    • Author(s)
      國井泰人
    • Organizer
      第39回 日本生物学的精神医学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] がんの免疫チェックポイント制御2017

    • Author(s)
      醍醐弥太郎
    • Organizer
      第14回日本癌治療学会アップデート教育コース
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 肺がん薬物療法のトピックスと展望2017

    • Author(s)
      醍醐弥太郎
    • Organizer
      第34回滋賀医学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 腫瘍免疫学と臨床試験2017

    • Author(s)
      醍醐弥太郎
    • Organizer
      帝京大学大学院講義・腫瘍内科学特論
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ヒト生体試料リソースによる研究支援2017

    • Author(s)
      醍醐弥太郎
    • Organizer
      コホート・生体試料支援プラットフォーム・シンボジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] がんの悪性化・難治化に関与する新規因子IL-34に関する研究2017

    • Author(s)
      清野研一郎
    • Organizer
      コホート・生体試料支援プラットフォーム・シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Dentification of candidate lung cancer neoantignes by systematic screening with next gencration sequencing2017

    • Author(s)
      Sumimoto H, Takano A, Teramoto K, Daigo Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Characterization of URSTI as a biomarker and therapeutic target for respiratory tract cancers2017

    • Author(s)
      Takano A, Yoshitake Y, Shinohara M, Miyagi Y, Daigo Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Improvement of anti-tumor responses by targeting hypoxia-mediated immunosuppression2017

    • Author(s)
      Teramoto K, Kataoka Y, Igarashi T, Sumimoto H, Daigo Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Monitoring of soluble PD-L1 levels in sera in non-small-cell lung cancer.2017

    • Author(s)
      Igarashi T, Hanaka J, Teramoto K, Daigo Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Identification of URSTI as a novel prognostic biomarker and therapeutic target for breast cancer2017

    • Author(s)
      Nakamura M, Takano A, Thang PM, Miyagi Y, Daigo Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Analysis of UROC4 as a new prognostic biomarker and therapeutic target for oral cancer2017

    • Author(s)
      Daigo K, Takano A, Yoshitake Y, Shinohara M, Daigo Y, Tohnai I, Murakami Y, Maegawa J
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Characterization of LASK2 as a therapeutic target for lung cancer2017

    • Author(s)
      Takahashi K, Takano A, Nakamura Y, Daigo Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Association of variations in HLA-class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma2017

    • Author(s)
      Shiraishi K, Daigo Y, Kubo M, Kohno T, et al.
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Immunological activities of adoptively transferred tumor antigen-specific CTLs costimulated with OX40 signaling in vitro2017

    • Author(s)
      Pham NM, Murata S, Daigo Y, Tani M, et al.
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Knockdown of TTK in ovarian cancer cells caused dysfunction of cell division, multinuclear cell formation and cell death2017

    • Author(s)
      Deng B, Park JH, Daigo Y, Nakamura Y
    • Organizer
      第76回日本癌学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] RORI : An Achilles Heel of Lung Cancer2017

    • Author(s)
      Takahashi T
    • Organizer
      24th Asia Pacific Cancer Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 受容体型チロシンキナーゼRORIによる生存シグナル維持の分子基盤2017

    • Author(s)
      高橋隆
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 作製条件によるセルブロックのゲノム診断試料としての品質評価2017

    • Author(s)
      宮城洋平
    • Organizer
      第36回神奈川県臨床細胞学会学術集会・教育セミナー
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 生命科学研究を支援する医療機関パイオバンク2017

    • Author(s)
      宮城洋平
    • Organizer
      横浜市立大学先端医科学研究センターセミナー
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 電気泳動法を基盤とする多発性骨髓腫の臨床と研究の進歩~はじめに~2017

    • Author(s)
      安井 寛
    • Organizer
      第68回日本電気泳動学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 臨床薬理学集中講座修了後の研究活動 ~橋渡し研究と医師主導治験を中心に~2017

    • Author(s)
      安井 寛
    • Organizer
      第38回日本臨床薬理学会学術総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Toll様受容体CD180を介した多発性骨髄腫の進展機序2017

    • Author(s)
      菊池次郎、黒田芳明、小山大輔、長田直希、和泉透、安井寛、川瀬孝和、一戸辰夫、古川雄祐
    • Organizer
      第42回日本骨髄腫学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 成人T細胞白血病リンパ腫に合併した急性骨髄性白血病治療中のウィルス感染症の発症2017

    • Author(s)
      神保光児、今井陽一、小川弥穂、平野光人、越智清純、川俣豊隆、横山和明、安井寛、大野伸広、内丸薫、東條有伸
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Toll様受容体CD180を介した多発性骨髄腫の進展機序2017

    • Author(s)
      菊地次郎、黒田芳明、小山大輔、長田直希、和泉透、安井 寛、川瀬孝和、一戸辰夫, 古川雄祐
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] A response to HTLV-1 in Japan”, HTLV-1 ; Re-awaking to HTLV-1 in indigenous communities2017

    • Author(s)
      Watanabe Toshiki
    • Organizer
      The 9th International Global Virus Network Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Phase 1/2 study of mogamulizumab, an anti-CCR4 Monoclonal antibody, in Patients with HTLV-1-associated myelopathy(HAM/TSP)2017

    • Author(s)
      Yamano Y, Sato T, A. Coler-Reilly, Yanagisawa N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y
    • Organizer
      XXIII World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ATL研究の現状-発症予防と個別化治療へ向けた展開-2017

    • Author(s)
      渡邉俊樹
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 成人T細胞白血病・リンパ腫(急性型・リンパ腫型)に対する治療と予後の実際に関する検討2017

    • Author(s)
      今泉芳孝、岩永正子、野坂生郷、伊藤薫樹、石塚賢治、宇都宮與、戸倉新樹、仲地佐和子、下田和哉、飛内賢正、渡邉俊樹、内丸薫、塚崎邦弘
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] EZH1/2阻害による悪性リンパ腫のエピゲノム制御2017

    • Author(s)
      山岸誠、堀真琴、藤川大、本間大輔、安達宣明、大杉剛生、中野和民、中島誠、小林誠一郎、岩永正子、宇都宮與、岡田誠治、塚崎邦弘、飛内賢正、荒木一司、渡邉俊樹
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ATL細胞の組織特異的遊走メカニズムの探索2017

    • Author(s)
      中野和民、野田奈津美、渡邉俊樹、内丸薫
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Molecular basis for clonal and malignant growth of HTLV-1-infected T-cells2017

    • Author(s)
      Toshiki Watanabe
    • Organizer
      Seminar, NIH, Washington
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Current status of HTLV-1 infection in Japan and molecular basis for ATL development2017

    • Author(s)
      Toshiki Watanabe
    • Organizer
      Seminar, Institut IMAGINE
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Current status of HTLV-1 infection in Japan and molecular basis for ATL development2017

    • Author(s)
      Toshiki Watanabe
    • Organizer
      Seminar, The University of Liege
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Current status of HTLV-1 infection in Japan and molecular basis for ATL development2017

    • Author(s)
      Toshiki Watanabe
    • Organizer
      Seminar, ENS de Lyon
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ATL研究の現状-発症予防と個別化治療へ向けた展開-2017

    • Author(s)
      渡邉俊樹
    • Organizer
      Kushiro Homatology Forum
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 細胞起源と遺伝子変異に基づいたEZH1/2標的個別化医療の開発2017

    • Author(s)
      山岸誠、藤川大、堀真琴、本間大輔、安達宣明、岩永正子、宇都宮與、岡田誠治、塚崎邦弘、飛内賢正、荒木一司、渡邉俊樹、内丸薫
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 慢性型およびくすぶり型ATL の予後の検討 : 第11次全国実態調査の解析結果2017

    • Author(s)
      今泉芳孝、岩永正子、野坂生郷、伊藤薫樹、石塚賢治、宇都宮與、戸倉新樹、仲地佐和子、森内幸美、林正樹、下田和哉、飛内賢正、渡邉俊樹、内丸薫、塚崎邦弘
    • Organizer
      第4回日本HTLV-1学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] FoxM1 : ATL細胞の新たな治療標的因子としての可能性2017

    • Author(s)
      山本菜央佳、中野和民、宇都宮與、渡邉俊樹、内丸薫
    • Organizer
      第4回日本HTLV-1学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 新規治療薬開発とATL発症予防介入へ向けた展開2017

    • Author(s)
      渡邉俊樹、山岸誠、中野和民、本間大輔、荒木一司、内丸薫
    • Organizer
      第4回日本HTLV-1学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] HTLV-1感染細胞におけるJAK/STAT経路の標的遺伝子の同定と機能的意義の検討2017

    • Author(s)
      石崎伊純、山岸誠、志賀遥菜、宇都宮與、田中勇悦、渡邉俊樹、内丸薫
    • Organizer
      第4回日本HTLV-1学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ATLの分子病態に基づく発症予防と個別化治療へ向けた展開2017

    • Author(s)
      渡邉俊樹
    • Organizer
      第57回日本リンバ網内系学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Physical activity reduces the risk of type 2 diabetes associated with m. 1382A>c polymorphism encoding 12S rRNA and mitochondria derived MOTS-c2016

    • Author(s)
      Fuku N, Zempo H, Nishida Y, Higaki Y, Naito H, Hara M, Tanaka K
    • Organizer
      APS Intersociety Meeting : The Integrative Biology of Exercise Ⅶ
    • Place of Presentation
      Phoenix, Arizona, USA
    • Year and Date
      2016-11-02
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Japan Multi-Institutional Collaborative Cohort Study. Genome-wide association study of sleep duration in the 14,000 Japanese general population2016

    • Author(s)
      Nishiyama T, Nakatochi M, Hosono A, Tamai Y, Suzuki S, Hishida A, Wakai K, Tanaka H, Matsuo K
    • Organizer
      ASHG2016
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2016-10-18
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Analysis of non-synonymous genetic variations associated with cancer risk by a prospective cohort study2016

    • Author(s)
      Yohko Nakamura, Yoshiaki Maru, Yasutoshi Tatsumi, Kazuhiro Okumura, Sana Yokoi, Miki Ohira, Yoshihiro Nabeya, Satoshi Fukasawa, Jin Katayama Hiroki Nagase, Haruo Mikami
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Monitoring of circulating PD-1+ cells and PD-1+ tumor-infiltrating lymphocytes in non-small-cell lung cancer2016

    • Author(s)
      Igarashi T, Kataoka Y, Hanaka J, Teramoto K, Daigo Y
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Characterization of UROC3 protein as a novel biomarker and a therapeutic target for oral cancer2016

    • Author(s)
      Thang PM, Takano A, Yoshitake Y, Shinohara M, Murakami Y, Daigo Y
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Non-coding RNA-mediated regulation of genes that are crucially involved in the molecular pathogenesis of lung cancer2016

    • Author(s)
      Takahashi T
    • Organizer
      第75回日本癌学会総会(シンボジウム)
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Serum uric acid in associated with within-visit blood pressure variability among women : the results of a five year survey from the J-MICC Daiko Study2016

    • Author(s)
      Okada R, Naito M, Morita E, Takagi S, Matsunaga T, Seiki T, Sasakabe T, Hattori Y, Kawai S, Hishida A, Hamajima N, Wakai K
    • Organizer
      Hypertension Seoul 2016 (The 26th Scientific Meeting of the International Society of Hypertension)
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 液性検体の質とTime Stampシンボジウム1・臨床検査と液性試料(検体) : 質の観点から2016

    • Author(s)
      宮城洋平
    • Organizer
      第63回日本臨床検査医学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Eating rate as obese risk and seasonal variation of abdominal fat.2016

    • Author(s)
      Kuriki K.
    • Organizer
      The 2016 International Congress on Obesity and Metabolic Syndrome in conjunction with the 45th Annual Scientific Meeting of the Korean Society for the Study of Obesity (ICOMES)
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-01
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 多発性骨髄腫における先端医療開発の今後2016

    • Author(s)
      安井 寛
    • Organizer
      第67回日本電気泳動学会
    • Place of Presentation
      釧路市観光国際交流センター(北海道釧路市)
    • Year and Date
      2016-08-25
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Polycomb-dependent epigenetic landscape in ATL : proof of concept for targeting EZH1/22016

    • Author(s)
      Watanabe T
    • Organizer
      Malignant Lymphoma Academy 2016
    • Place of Presentation
      シェラトン都ホテル東京(東京都港区)
    • Year and Date
      2016-08-06
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Association Between Remnal Functions and SCFBiomarkers in Alzheimer's Disease.2016

    • Author(s)
      Kanemaru K, Kanemaru A, Murayama S.
    • Organizer
      Alzheimer's Association International Conference (AAIC2016)
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2016-07-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Epigenetic Regulation of BRCA1 in Alzheimer's Disease. Evaluation of Post-Mortem Brain-and Model Mice Reveals Importance of Aggregated Tau2016

    • Author(s)
      Mano T, Ohtomo R, Nagata K, Murayama S, Saido T. C, Yamashita S, Ushijima T, Hashimoto T, Tamaoka A, Iwatsubo T, Tsuji S, Iwata A
    • Organizer
      Alzheimer's Association International Conference (AAIC2016)
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2016-07-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Enhanced Pla2g3 Expression By Oxidative Stress Decreases the Ide and Exacerbates AD2016

    • Author(s)
      Nishida Y, Yui D, Nishina T, Mogushi K, Ishibashi S, Ajioka I, Ishikawa K, Mizusawa H, Murayama S, Yokota T
    • Organizer
      Alzheimer's Association International Conference (AAIC2016)
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2016-07-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between the cholesterol and triglyceride content of lipoprotein subclasses and carotid intima media thickness : Results from the Kyushu and Okinawa Population Study2016

    • Author(s)
      Furusyo N, Shimizu M, Kato Y, Tanaka Y, Hayashi J.
    • Organizer
      The 84th European Atherosclerosis Society (EAS) Congress
    • Place of Presentation
      Innsbruck, Austria
    • Year and Date
      2016-05-29
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] エオジン好性核内封入体病における機能画像・髄液バイオマーカーの検討2016

    • Author(s)
      仙石錬平, 渋川菜莉, 本山りえ, 森本 悟, 砂川昌子, 金田大太, 仁科裕史, 豊原 潤, 藤ヶ﨑純子, 石井賢二, 金丸和富, 村山繁雄
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2016-05-18
    • Related Report
      2016 Annual Research Report
  • [Presentation] Neuropathological examination of familial Parkinson's disease with LRRK2I2020T mutation.2016

    • Author(s)
      Uchino A, Fujigasaki J, Hasegawa K, Yagishita S, Oonuma S, Ogino M, Ogino Y, Nakano Y, Murayama S, Nishiyama K
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンペンションセンター(兵庫県神戸市)
    • Year and Date
      2016-05-18
    • Related Report
      2016 Annual Research Report
  • [Presentation] 遺伝性腫瘍症2016

    • Author(s)
      醍醐弥太郎
    • Organizer
      第27回日本人類遺伝学会・遺伝医学セミナー
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Book] Newton : 「死」と「生」の境界線 死とは何か? 寿命をのばすことは可能なのか?2017

    • Author(s)
      岩瀬博太郎, 岡田隆夫, 川上嘉明, 小林武彦, 村山繁雄
    • Total Pages
      37
    • Publisher
      ニュートンプレス
    • Related Report
      2017 Annual Research Report
  • [Book] A Literature Review of the Associations between Sedentary Behavior and Health-Related Outcomes in Japan. Leon V. Berhardt, eds.2017

    • Author(s)
      Ukawa S, Shirakawa T, Kikuchi H, Ikehara S, Inoue S, Iso H, Tamakoshi A.
    • Pages
      93-107
    • Total Pages
      239
    • Publisher
      NOVA science publishers. New York
    • Related Report
      2016 Annual Research Report
  • [Book] 神経内科 第84巻第6号2016

    • Author(s)
      小山晃英、渡邊能行、栗山長門
    • Publisher
      科学評論社
    • Related Report
      2016 Annual Research Report
  • [Remarks] コホート・生体試料支援プラットフォームホームページ

    • URL
      http://cohort.umin.jp/
    • Related Report
      2017 Annual Research Report
  • [Remarks] 東京大学医科学研究所 学術研究基盤支援室ホームページ

    • URL
      http://academicsupport.jp/index.html
    • Related Report
      2017 Annual Research Report
  • [Remarks] J-MICC STUDYホームページ

    • URL
      http://www.jmicc.com
    • Related Report
      2017 Annual Research Report
  • [Remarks] ICOMES : 2016 International Congress on Obesity and Metabolic Syndrome "Understanding, Manageing & Preventing Obesity and Meatabolic Syndrome" Symmposium 10 Looking for Successful Nutritional Approaches to Obesity & Metabolic Syndrome

    • URL
      http://www.icomes.or.kr/register/2016_icomos/program/sub02_03.html
    • Related Report
      2017 Annual Research Report
  • [Remarks] 千葉県がんセンター研究所ホームページ

    • URL
      http://www.pref.chiba.lg.jp/gan/kenkyujo/
    • Related Report
      2017 Annual Research Report
  • [Remarks] 千葉県がんセンター研究所フェイスブック

    • URL
      https://m.faccbook.com/CCCRI.chiba.gan.kenkyu.jo
    • Related Report
      2017 Annual Research Report
  • [Remarks] 京都府立医科大学地域保健医療疫学教室ホームページ

    • URL
      http://www.f.kpu-m.ac.jp/k/cpid/index.html
    • Related Report
      2017 Annual Research Report
  • [Remarks] 九州大学医学研究院 感染制御医学分野ホームページ

    • URL
      http://www.soshin.med.kyushu-u.ac.jp/
    • Related Report
      2017 Annual Research Report
  • [Remarks] 精神疾患プレインバンク・DNAバンクホームページ

    • URL
      http://www.fmu-bb.jp/
    • Related Report
      2017 Annual Research Report
  • [Remarks] 2017年10月29日(日)毎日新聞記事掲載

    • URL
      https://mainichi.jp/articles/20171029/ddm/016/040/048000c
    • Related Report
      2017 Annual Research Report
  • [Remarks] J-MICC Study

    • URL
      http://www.jmicc.com
    • Related Report
      2016 Annual Research Report
  • [Remarks] 千葉県がんセンター研究所 予防疫学研究部

    • URL
      https://www.pref.chiba.lg.jp/gan/kenkyujo/soshiki/yoboekigaku/index.html
    • Related Report
      2016 Annual Research Report
  • [Remarks] ICOMES : 2016 International Congress on Obesity and Metabolic Syndrome "Understanding, Manageing & Preventing Obesity and Meatabolic Syndrome" Symposium 10 Looking for Successful Nutritional Approaches to Obesity & Metabolic Syndrome

    • URL
      http://www.icomes.or.kr/register/2016_icomes/program/sub02_03.html
    • Related Report
      2016 Annual Research Report
  • [Remarks] J-MICC Study(ジェイミック・スタディ)佐賀フィールドとは

    • URL
      http://www.prevent.med.saga-u.ac.jp/jmiccsaga.html
    • Related Report
      2016 Annual Research Report
  • [Remarks] 九州大学病院 総合診療科(感染環境医学分野)

    • URL
      http://www.soshin.med.kyushu-u.ac.jp/
    • Related Report
      2016 Annual Research Report
  • [Remarks] JACC Study

    • URL
      http://publichealth.med.hokudai.ac.jp/jacc/
    • Related Report
      2016 Annual Research Report
  • [Remarks] コホート・生体試料支援プラットフォーム「生体試料による支援活動」

    • URL
      http://cohort.umin.jp/about/bio-specimen.html
    • Related Report
      2016 Annual Research Report
  • [Remarks] プラットフォームHPのURL

    • URL
      http://cohort.umin.jp/index.html
  • [Patent(Industrial Property Rights)] AD診断技術2017

    • Inventor(s)
      吉宗一晃、赤津裕康、神野英毅
    • Industrial Property Rights Holder
      吉宗一晃、赤津裕康、神野英毅
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-045244
    • Filing Date
      2017
    • Application Year
      2017
    • Related Report
      2017 Annual Research Report

URL: 

Published: 2016-12-27   Modified: 2019-03-20  

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