| Co-Investigator(Kenkyū-buntansha) |
Tin・Tin Win・Shwe 国立研究開発法人国立環境研究所, 環境リスク・健康研究センター, 主任研究員 (00391128)
井上 健一郎 静岡県立大学, 看護学部, 教授 (20373219)
小池 英子 国立研究開発法人国立環境研究所, 環境リスク・健康研究センター, 室長 (60353538)
柳澤 利枝 国立研究開発法人国立環境研究所, 環境リスク・健康研究センター, 主任研究員 (70391167)
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| Budget Amount *help |
¥180,700,000 (Direct Cost: ¥139,000,000、Indirect Cost: ¥41,700,000)
Fiscal Year 2020: ¥28,990,000 (Direct Cost: ¥22,300,000、Indirect Cost: ¥6,690,000)
Fiscal Year 2019: ¥32,370,000 (Direct Cost: ¥24,900,000、Indirect Cost: ¥7,470,000)
Fiscal Year 2018: ¥53,690,000 (Direct Cost: ¥41,300,000、Indirect Cost: ¥12,390,000)
Fiscal Year 2017: ¥26,910,000 (Direct Cost: ¥20,700,000、Indirect Cost: ¥6,210,000)
Fiscal Year 2016: ¥38,740,000 (Direct Cost: ¥29,800,000、Indirect Cost: ¥8,940,000)
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| Outline of Final Research Achievements |
The present study elucidated the fundamental mechanisms by which environmental pollutants enhance allergic diseases and the critical molecules for the enhancement. On the other hand, in vitro screening was useful for identifying environmental substances/factors that can aggravate allergic responses. Furthermore, in vivo evaluation after in vitro screening should be the best and most practical method for assessing the aggravating effects of environmental substances/factors on allergies. Our comprehensive and systematic study can contribute to the control/eradication of allergic diseases via medical and environmental approaches.
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