| Project/Area Number |
16H06689
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Sports science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2016-08-26 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 骨格筋 / グリコーゲン / 解糖系 / ピルビン酸脱水素酵素 / 運動後 / 回復 / 糖質酸化 / スポーツ科学 / 運動生理生化学 / グリコーゲン回復 |
|---|
| Outline of Final Research Achievements |
Many researchers and athletes have been interested to know how post-exercise glycogen resynthesis can be enhanced in skeletal muscle. However, it has been suggested that there is an upper limit of resynthesis rate of skeletal muscle glycogen. Meanwhile, recent studies suggested that reducing carbohydrate utilization as a fuel during post-exercise phase might enhance skeletal muscle glycogen repletion. In this study, we investigated using in vitro system whether treatment of the regent that is expected for attenuating carbohydrate utilization as an energy fuel stimulates glycogen repletion in skeletal muscle after exercise. We found a significant effect of ketone body, which is reported to reduce the activity of pyruvate dehydrogenase, on post-exercise glycogen repletion in skeletal muscle.
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