Identification of cell population accelating craniofacial fracture using multiple differentiation method with pluripotent stem cell
| Project/Area Number |
16H06762
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Kanke Kosuke 東京大学, 医学部附属病院, 助教 (90779810)
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 多能性幹細胞 / 骨芽細胞 / 顎顔面骨骨折 |
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| Outline of Final Research Achievements |
This study designed which cell population contributes to bone healing in craniofacial fracture with ositeobleast induction using plurioptent stem cell. During induction, genes of Dermo1, Runx2, Sp7 and Bglap highly expressed at day 9, day Day 19 and Day 23, respectively. Genes of Runx2 ann Sp7 were expressed at the same levels of these of primary osteoblasts. 2.3kb Col1a1 was highly expressed as well. We are researching how these populations contirbute to craniofacial bone fracture healing.
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Report
(3 results)
Research Products
(8 results)
