Evaluation of porous luminal structure beta-TCP with growth factor and development of new bone substitute materials
| Project/Area Number |
16H06780
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontology
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
IKAWA Takahiro 東京医科歯科大学, 大学院医歯学総合研究科歯周病学分野, 非常勤講師 (20780290)
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 骨補填剤 / 歯周組織再生 / 再生医療 / インプラント / 成長因子 / 骨再生 / 歯周病 / 骨補填材 / 再生医学 / 歯学 / 生体材料 / 組織工学 |
|---|
| Outline of Final Research Achievements |
Bone substitute materials are indispensable for periodontal regeneration and implant treatment. This study evaluated histologically localized ridge augmentation using different structures of β-TCP including luminal structure β-TCP blocks, dense β-TCP blocks, and β-TCP granule. Though we couldn't develop the new bone substitute materials, luminal structure may have a greater potential for new bone formation. We successfully showed that FGF-2 in gelatin/β-TCP sponges increased potential to support periodontal wound healing.
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Report
(3 results)
Research Products
(8 results)
