• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Investigation of novel bio-marker by urine proteomics and establishment for early diagnosis by two-dimensional approach for urological cancer

Research Project

Project/Area Number 16H06814
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Epidemiology and preventive medicine
Research InstitutionNiigata University

Principal Investigator

Saito Suguru  新潟大学, 医歯学総合研究科, 客員研究員 (50776721)

Research Collaborator Yamamoto Tadashi  新潟大学・生体液バイオマーカーセンター, 地域創成推進機構, 特任教授
Hirao Yoshitoshi  新潟大学・生体液バイオマーカーセンター, 地域創成推進機構, 特任准教授
Project Period (FY) 2016-08-26 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords尿プロテオミクス / 泌尿器癌 / バイオマーカー / 表面プラズモン共鳴 / 尿タンパク質 / 早期診断 / 予防医学 / プロテオミクス / 質量分析 / 分子間相互作用解析
Outline of Final Research Achievements

Throughout this project, we completed that establishment of the technology in novel bio marker investigation and detection for early diagnosis of urological cancer. In the investigation of bio-marker, we established original analysis platform based on urine proteomics, so that we were success to identify the candidate of novel bio-marker with high accuracy. In the detection of bio-marker, we adopted SPR technique for direct detection of bio-marker in the urine sample. These results are important basic skill for early diagnosis of urological cancer. Based on the skills, further development will be estimated for clinical use.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • Research Products

    (4 results)

All 2018 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Proteome Profiling of Diabetic Mellitus Patient Urine for Discovery of Biomarkers by Comprehensive MS-Based Proteomics2018

    • Author(s)
      Hirao Yoshitoshi、Saito Suguru、Fujinaka Hidehiko、Miyazaki Shigeru、Xu Bo、Quadery Ali、Elguoshy Amr、Yamamoto Keiko、Yamamoto Tadashi
    • Journal Title

      Proteomes

      Volume: 6 Issue: 1 Pages: 9-9

    • DOI

      10.3390/proteomes6010009

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Urine protein preparation workflow for urine proteomics2017

    • Author(s)
      Saito S, Hirao Y, Xu B, Quadery AF, Elguoshy A, Yamamoto K, Yamamoto T.
    • Organizer
      HUPO
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Urine protein preparation workflow for urine proteomics2017

    • Author(s)
      Saito S, Hirao Y, Xu B, Quadery AF, Elguoshy A, Yamamoto K, Yamamoto T.
    • Organizer
      JHUPO
    • Related Report
      2017 Annual Research Report
  • [Presentation] Total workflow of urine protein preparation2016

    • Author(s)
      Suguru Saito, Yoshitoshi Hirao, Bo Xu, Ali F Quadery, Amr ElGuoshy, Keiko Yamamoto, Tadashi Yamamoto
    • Organizer
      HUPO 2016
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2016-09-18
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research

URL: 

Published: 2016-09-02   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi