Investigation of novel bio-marker by urine proteomics and establishment for early diagnosis by two-dimensional approach for urological cancer
| Project/Area Number |
16H06814
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Niigata University |
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Principal Investigator |
Saito Suguru 新潟大学, 医歯学総合研究科, 客員研究員 (50776721)
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| Research Collaborator |
Yamamoto Tadashi 新潟大学・生体液バイオマーカーセンター, 地域創成推進機構, 特任教授
Hirao Yoshitoshi 新潟大学・生体液バイオマーカーセンター, 地域創成推進機構, 特任准教授
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Keywords | 尿プロテオミクス / 泌尿器癌 / バイオマーカー / 表面プラズモン共鳴 / 尿タンパク質 / 早期診断 / 予防医学 / プロテオミクス / 質量分析 / 分子間相互作用解析 |
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| Outline of Final Research Achievements |
Throughout this project, we completed that establishment of the technology in novel bio marker investigation and detection for early diagnosis of urological cancer. In the investigation of bio-marker, we established original analysis platform based on urine proteomics, so that we were success to identify the candidate of novel bio-marker with high accuracy. In the detection of bio-marker, we adopted SPR technique for direct detection of bio-marker in the urine sample. These results are important basic skill for early diagnosis of urological cancer. Based on the skills, further development will be estimated for clinical use.
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Report
(3 results)
Research Products
(4 results)
