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Application of autogenic amnion for the treatment of cleft lip and palate

Research Project

Project/Area Number 16H06821
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionUniversity of Toyama

Principal Investigator

Tsuno Hiroaki  富山大学, 附属病院, 講師 (70377290)

Project Period (FY) 2016-08-26 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords羊膜 / 口唇口蓋裂 / 自家組織 / ヒト乾燥羊膜 / 口蓋形成術 / 間葉系細胞
Outline of Final Research Achievements

The purpose of this study is to evaluate the difference on the amnion between normal babies (control) and babies with cleft lip and palate(CLP), assuming the application of autogenic amniotic membrane for the treatments. During the study period, only one sample of the amnion from CLP baby. There seems no difference on morphological finding of fresh amnion within two groups. Hyper-dry amniotic membranes were also produced and tested by physical examinations. Similar characteristics on mechanical strength were found in two groups, but statistical analysis has not been performed for insufficient number of samples. Further investigations also have been continued with sufficient number of samples.

Report

(2 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (2 results)

All 2016

All Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Clinical application of hyper-dried amniotic membrane for surgical repair of oral mucosal defect2016

    • Author(s)
      Hiroaki TSUNO, Kumiko FUJIWARA, Shuichi IMAUE, Makoto NOGUCHI, Katsuhisa SEKIDO, Kei TOMIHARA
    • Organizer
      12th asian congress on oral and maxillofacial surgery
    • Place of Presentation
      Manila,Philippines
    • Year and Date
      2016-11-09
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ヒトハイパードライ羊膜の口腔内手術創への応用2016

    • Author(s)
      津野宏彰、野口 誠
    • Organizer
      第15回日本組織移植学会総会・学術大会
    • Place of Presentation
      富山市
    • Related Report
      2016 Annual Research Report

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Published: 2016-09-02   Modified: 2018-03-22  

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