Characteristics of carbapenem-resistant Enterobacteriaceae isolateid in Southeast Asia
Project/Area Number |
16H06946
|
Research Category |
Grant-in-Aid for Research Activity Start-up
|
Allocation Type | Single-year Grants |
Research Field |
Bacteriology (including mycology)
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Research Institution | Osaka University |
Principal Investigator |
Sugawara Yo 大阪大学, 微生物病研究所, 特任助教(常勤) (70452464)
|
Research Collaborator |
HAGIYA Hideharu
|
Project Period (FY) |
2016-08-26 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | カルバペネム耐性 / 腸内細菌科細菌 / プラスミド / 薬剤耐性菌 / カルバペネム / 細菌 / 抗生物質 / ゲノム / 感染症 |
Outline of Final Research Achievements |
Spread of carbapenem-resistant Enterobacteriaceae (CRE) has become worldwide concern. In this study, I sought to clarify the characteristics of the CRE strains prevalent in Southeast Asia and their relevance to epidemiology. In Myanmar, two types of plasmids harboring the NDM gene, one of the most prevalent carbepenemase gene worldwide, were prevalent among obtained CRE isolates. They showed different characters in terms of antimicrobial susceptibility and the efficiency of transfer, apparently supporting their differential spread.
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Report
(3 results)
Research Products
(1 results)