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Identification of risk factor of CKD and pathogenic bacteria of infectious complications in dialysis

Research Project

Project/Area Number 16H06989
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Prosthodontics/ Dental materials science and
Research InstitutionOkayama University

Principal Investigator

KOYAMA Eri  岡山大学, 大学病院, 医員 (60779437)

Research Collaborator KUBOKI Takuo  岡山大学, 医歯薬学総合研究科, 教授 (00225195)
ONO Aya  岡山大学, 大学病院, 助教 (20584626)
ONO Mitsuaki  岡山大学, 医歯薬学総合研究科, 助教 (60613156)
AKIYAMA Kentaro  岡山大学, 大学病院, 講師 (70423291)
Project Period (FY) 2016-08-26 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords歯学 / 口腔内細菌 / 慢性腎臓病 / 感染シャント / 16SrRNA / 16sRNA / 細菌 / 解析・評価
Outline of Final Research Achievements

In our country, the chronic kidney disease (CKD) patients increase year by year, and it is reported that oral health is related to life prognosis and the onset of complications in CKD patients, and the relationship between oral and kidney is attracting a great deal of attention.

Therefore, the goal of this study is to identify the bacterial flora in shunt infection and clarify the relationship between oral flora and shunt infection. From the results of 16S rRNA analysis, the ratio of staphylococcus in saliva of several patients was abnormally high and oral flora of saliva was similar to that of infected shunt.And we also found that the oral disease-related bacteria existed in the infected shunt.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • Research Products

    (2 results)

All 2018 2017

All Presentation (2 results)

  • [Presentation] NGSを用いた透析患者感染シャントの16S菌叢解析2018

    • Author(s)
      Ha Thi Thu NGUYEN ,大野充昭,大野 彩,小盛大志,小山絵理,窪木拓男
    • Organizer
      第7回補綴若手研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 地域在住高齢者における低体重および低栄養発生のリスク因子の検討2017

    • Author(s)
      小山絵理
    • Organizer
      公益社団法人日本補綴歯科学会第126回学術大会
    • Related Report
      2017 Annual Research Report

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Published: 2016-09-02   Modified: 2019-03-29  

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