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Research for the regulation of HMGB1 in the interstitial lung disease

Research Project

Project/Area Number 16H07050
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Respiratory organ internal medicine
Research InstitutionKyushu University

Principal Investigator

Yanagihara Toyoshi  九州大学, 大学病院, 助教 (40778841)

Research Collaborator KIYOHARA Chikako  九州大学, 大学院医学研究院予防医学分野, 講師
Project Period (FY) 2016-08-26 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords間質性肺炎 / ゲノム / 特発性間質性肺炎 / HMGB1 / SP-A / シグナル伝達 / レクチン様ドメイン / 遺伝子 / 内科
Outline of Final Research Achievements

We have conducted a prospective cohort study to fully investigate tobacco-related lung diseases including idiopathic interstitial pneumonitis in 29 hospitals in Fukuoka Prefecture. Using genome from this cohort, we have started seaching polymorphisms in idiopathic interstitial pneumonitis in Japanese populations.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • Research Products

    (1 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Bax-inhibiting peptide attenuates bleomycin-induced lung injury in mice2017

    • Author(s)
      Suzuki Kunihiro、Yanagihara Toyoshi、Yokoyama Tetsuya、Maeyama Takashige、Ogata-Suetsugu Saiko、Arimura-Omori Masako、Mikumo Hironori、Hamada Naoki、Harada Eiji、Kuwano Kazuyoshi、Harada Taishi、Nakanishi Yoichi
    • Journal Title

      Biology Open

      Volume: 6 Pages: 1869-1875

    • DOI

      10.1242/bio.026005

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access

URL: 

Published: 2016-09-02   Modified: 2019-03-29  

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