Detection and identification of Archaea in dental plaque, and investigation of the association between oral health and Archaea

• Project/Area Number: 16H07068
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Social dentistry
• Research Institution: Kyushu University
• Principal Investigator: Matsumi Rie 九州大学, 歯学研究院, 助教 (90397597)
• Project Period (FY): 2016-08-26 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: アーキア / 古細菌 / 口腔 / 歯周病 / 縁下プラーク / 微生物 / 口腔内微生物 / 歯肉縁下 / メタン菌

Outline of Final Research Achievements

This study confirmed that DNA obtained from subgingival plaque in patients with periodontitis contained archaeal genomes. Archaeal groups such as Crenarchaeota and DPANN were included in addition to the genus Methanobrevibater, which was previously reported. The results suggest that a diverse Archaeome may be formed in the oral cavity.