Development of polymeric materials with a highly sensitive mechanoprobe based on charge-transfer interaction and application to mechanobiology
| Project/Area Number |
16H07292
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Polymer chemistry
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| Research Institution | Waseda University |
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Principal Investigator |
Imato Keiichi 早稲田大学, 理工学術院, 助教 (80777970)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKEDA Naoya 早稲田大学, 理工学術院先進理工学部, 教授 (60338978)
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| Research Collaborator |
NAKAJIMA Hidekazu
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 高分子材料 / メカノケミストリー / メカノクロミズム / メカノバイオロジー / 自己修復 / 電荷移動相互作用 / 高分子化学 / 応力検出 / 超分子化学 / 生体材料 / 電荷移動錯体 / 蛍光分子 / 分子プローブ |
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| Outline of Final Research Achievements |
In this study, we tried to develop a highly sensitive mechanoprobe based on charge transfer (CT) interaction between fluorescent molecules that reversibly dissociate and associate, and incorporate it into polymer chains, in order to reversibly detect microstress in polymeric materials. The designed probe and polymeric materials with it were successfully synthesized, but the reversible detection of microstress could not be achieved. On the other hand, when CT interaction was utilized as reversible physical cross-linking points in polymeric materials (elastomers), the elastomers showed self-healing in mild environments and could be used as cell culture scaffolds.
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Report
(3 results)
Research Products
(11 results)
