| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
We have developed the synthetic method of phenol cross-coupling products by the introduction of phenols into quinone monoacetals (QMAs). This method can efficiently provide the regioselectively connected products by the activation of acetal moiety on QMAs under mild condition. Moreover, we have presented that this reaction proceeds by the nucleophilic substitution mechanism and can be applied for various nucleophiles. Furthermore, useful skeletons, such as phenol-trimer and dibenzofuran, could be constructed by the applicable methods from phenol cross-coupling products.
|
