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Dynamics in Cortical Network of Resonator neurons

Research Project

Project/Area Number 16K00386
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Life / Health / Medical informatics
Research InstitutionYamagata University

Principal Investigator

Kang Siu  山形大学, 大学院理工学研究科, 助教 (40415138)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords神経回路シミュレーション / 閾値下共鳴 / スパイクタイミング依存可塑性 / ニューラルネットワーク / 脳型情報処理 / 記憶と学習 / 計算神経科学 / STDP / シナプス可塑性 / 自己組織化 / 再帰結合回路
Outline of Final Research Achievements

Recent electrophysiological recording revealed that some types of neuron showed relatively strong response for specific frequency under their subthreshold level. Single neuronal property of such the subthreshold resonance was well examined, however, network behavior of the resonator is unclear. Particularly, its roll in circuit formation through the synaptic plasticity which provides higher order cortical function such as learning and memory is still unknown. In the present study, it is computationally examined how the resonator network stores the information of external stimuli and modifies network connectivity under the oscillatory background and noise.

Academic Significance and Societal Importance of the Research Achievements

閾値下共鳴現象を示す神経細胞から成る回路網が、周期背景入力とノイズの下で、シナプス可塑性を通じた学習を行う場合に、外部刺激に対する学習が周波数選択的に行われることが明らかになった。言い換えると、受け手側の回路が受ける周期入力の周波数に応じて、外部刺激に対する学習の仕方が異なるということが計算機シミュレーションによって示された。また、このような周波数に依存した学習の違いは、周期入力とともに与えられるノイズの強度が適度な場合にのみ生じることが明らかになった。この研究により、注意関連情報処理などといった高次脳機能に対する、神経回路レベルからの理解につながることが期待される。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (5 results)

All 2019 2018 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (4 results) (of which Int'l Joint Research: 4 results)

  • [Journal Article] Cortical learning through the spike-timing-dependent plasticity modulated by intrinsic membrane potential fluctuation2019

    • Author(s)
      Taishi Matsumura, Tetsuya Yuasa, Siu Kang
    • Journal Title

      Journal of Advanced Simulation in Science and Engineering

      Volume: 印刷中

    • NAID

      130007612086

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Cortical learning through the spike-timing-dependent plasticity modulated by the intrinsic membrane potential fluctuation2018

    • Author(s)
      Taishi Matsumura, Tetsuya Yuasa, Siu Kang
    • Organizer
      International Conference on Simulation Technology (JSST2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Inhibition-mediated organization of cortical circuit through the spike-timing-dependent plasticity2017

    • Author(s)
      Taishi Matsumura, Tetsuya Yuasa, Siu Kang
    • Organizer
      NOLTA2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Cortical circuit organized through the log-STDP leads to an internal representation of sensory experience during development: a model study2016

    • Author(s)
      Taishi Matsumura, Tetsuya Yuasa and Siu Kang
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience 2016)
    • Place of Presentation
      San Diego, US
    • Year and Date
      2016-11-12
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Synaptic learning of the resonator network interacting with oscillatory background and noise2016

    • Author(s)
      Taishi Matsumura, Tatsuo Kitajima, Tetsuya Yuasa and Siu Kang
    • Organizer
      The 9th Eurosim Congress on Modelling and Simulation
    • Place of Presentation
      Oulu, Finland
    • Year and Date
      2016-09-12
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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