| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
We here investigated if low dose /low dose rate radiation exposure elicits delayed instability as high dose radiation exposure did. We established the immortalized cells from femoral muscle of wild Japanese Macaque living in ex-evacuation zone. Compared with the immortalized cells established from the muscle of control Japanese Macaque, delayed effects shown as induction of DNA double-strand breaks or global methylation did not appear even in the cells made from exposed Japanese Macaque. Based on the system we here established, investigation using tissue other than muscle is necessary to comprehensively discuss radiation effect among different organs.
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