| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
The prevalence of NAFLD has increased with the increased prevalence of obesity and metabolic syndrome. Recent studies indicate that NAFLD onset and progression may be influenced by the nutrients in food as well as the total calories ingested. However, it isn’t revealed whether protein in food prevents NAFLD progression. In this study, we evaluated the potential of mung bean protein isolate (MPI) to prevent NAFLD progression. MPI decreased the hepatic triglyceride concentration by inhibition of fatty acid synthesis. Additionally, NAFLD progression by atherogenic diet was prevented by MPI intake. These results indicate that MPI reduced hepatic triglyceride accumulation and may be a food to prevent NAFLD progression.
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