• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of a method for imaging the speed of sound distribution of biological tissue by multimodal measurements

Research Project

Project/Area Number 16K01432
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

Nitta Naotaka  国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 (60392643)

Research Collaborator Numano Tomokazu  
Kaya Akio  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords画像診断システム / 医療・福祉 / 生物・生体工学 / 超音波 / 磁気共鳴画像化法 / 音速
Outline of Final Research Achievements

It is known that the speed of sound of ultrasound propagating through biological tissues is correlated with the tissue degenerations due to diseases, and the imaging of the speed of sound distribution is expected to be useful in the diagnostic imaging for identifying diseased sites. Therefore, in this study, we investigated a method of imaging the speed of sound distribution by combining the ultrasonic imaging method and the magnetic resonance imaging method. As a result of fabricating an ultrasonic array transducer available inside the magnetic resonance imaging device and conducting the experimental verification using a tissue-mimicking material, the feasibility of the proposed method was suggested.

Academic Significance and Societal Importance of the Research Achievements

生体組織を伝搬する超音波の音速は、疾病等による組織変性と相関がある。例えば、多くの腫瘍では、その周囲の正常な軟組織とは異なる音速を有することが知られており、また、変形性膝関節症初期における関節軟骨の変性はプロテオグリカンの減少とコラーゲンマトリックスの構造変化によって生じ、その結果として音速が変化し得る。このような音速の変化が捉えられれば、多くの疾病に対する早期発見が可能になるものと期待される。このことから、本研究成果は疾病の早期発見に資するものであると言える。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (6 results) (of which Int'l Joint Research: 3 results) Remarks (1 results)

  • [Journal Article] Interpretation of Physical Meaning of Speed of Sound in Cartilage Tissue: Through Comparison with Elasticity and Magnetic Resonance Parameters2018

    • Author(s)
      Nitta Naotaka、Misawa Masaki、Numano Tomokazu
    • Journal Title

      2018 IEEE International Ultrasonics Symposium Proceedings

      Volume: - Pages: 1-4

    • DOI

      10.1109/ultsym.2018.8579946

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Accuracy improvement of multimodal measurement of speed of sound based on image processing2017

    • Author(s)
      Nitta Naotaka、Kaya Akio、Misawa Masaki、Hyodo Koji、Numano Tomokazu
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 56 Issue: 7S1 Pages: 07JF17-07JF17

    • DOI

      10.7567/jjap.56.07jf17

    • NAID

      210000148079

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 軟骨組織における音速と他の物理量との相関性について ― マルチモーダル測定に基づく検討 ―2018

    • Author(s)
      新田尚隆, 賀谷彰夫, 三澤雅樹, 兵藤行志, 沼野智一
    • Organizer
      日本超音波医学会平成30年度第2回基礎技術研究会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Interpretation of Physical Meaning of Speed of Sound in Cartilage Tissue: Through Comparison with Elasticity and Magnetic Resonance Parameters2018

    • Author(s)
      Naotaka Nitta, Masaki Misawa, Tomokazu Numano
    • Organizer
      2018 IEEE International Ultrasonics Symposium
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multimodal measurement of acoustic properties in cartilage tissue2016

    • Author(s)
      新田尚隆, 賀谷彰夫, 三澤雅樹, 兵藤行志, 沼野智一
    • Organizer
      5th Joint Meeting Acoustical Society of America and Acoustical Society of Japan
    • Place of Presentation
      Hilton Hawaiian Village(Honolulu, USA)
    • Year and Date
      2016-12-02
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Accuracy Improvement of Multimodal Measurement of Speed of Sound Based on Image Processing2016

    • Author(s)
      新田尚隆, 賀谷彰夫, 三澤雅樹, 兵藤行志, 沼野智一
    • Organizer
      The 37th Symposium on Ultrasonic Electronics (USE2016)
    • Place of Presentation
      釜慶大学(釜山, 韓国)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] マルチモーダル音速測定による組織性状評価2016

    • Author(s)
      新田尚隆, 賀谷彰夫, 三澤雅樹, 兵藤行志, 沼野智一
    • Organizer
      日本超音波医学会第28回関東甲信越地方会学術集会
    • Place of Presentation
      TFTホール(東京都江東区)
    • Year and Date
      2016-10-22
    • Related Report
      2016 Research-status Report
  • [Presentation] マルチモダリティ音速測定法の精度改善に関する検討2016

    • Author(s)
      新田尚隆, 賀谷彰夫
    • Organizer
      平成28年度第3回基礎技術研究会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2016-08-06
    • Related Report
      2016 Research-status Report
  • [Remarks] 産総研健康工学研究部門セラノスティックデバイス研究グループ

    • URL

      https://unit.aist.go.jp/hri/group/2015_td-4/index.html

    • Related Report
      2018 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi