Prediction and validation of total and regional fat and skeletal muscle mass in pubertal Japanese children

• Project/Area Number: 16K01601
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Developmental mechanisms and the body works
• Research Institution: J. F. Oberlin University
• Principal Investigator: MIDORIKAWA Taishi 桜美林大学, 健康福祉学群, 准教授 (50434345)
• Project Period (FY): 2016-04-01 – 2023-03-31
• Project Status: Completed (Fiscal Year 2022)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
• Keywords: 身体組成 / 子ども / 骨格筋量 / 脂肪量 / 推定式 / MRI / DXA / 発育発達

Outline of Final Research Achievements

Information about total and regional fat and skeletal muscle mass in pubertal children is limited. The mass and distribution of fat and skeletal muscle using DXA and MRI methods were analyzed in 18 pubertal boys and girls in this study. When applying prediction equations for estimating fat and skeletal muscle mass in prepubertal children to pubertal children, significant differences in several cases were found using skinfold caliper and B-mode ultrasonography.

Academic Significance and Societal Importance of the Research Achievements

・思春期にある子どもの身体をターゲットとした研究をスタートするにあたり、脂肪や骨格筋の量や分布に関する情報は極めて貴重な基礎データとなる。
・脂肪や骨格筋の定量法として最も精度が高いDXA法とMRI法を基準として、子どもにも安全に使用できる簡易推定法を検討・開発している。皮下脂肪厚計や超音波装置を用いた推定式は、研究での使用のみならず、教育・医療現場においても利用を想定している。

Research Products

• [Journal Article] Prediction and validation of total and regional skeletal muscle volume by using anthropometric measurements in prepubertal Japanese children (2022)
  • Author(s): Midorikawa T, Ohta M, Hikihara Y, Torii S, Sakamoto S.
  • Journal Title: British Journal of Nutrition Volume: 27 Issue: 2 Pages: 1-7
  • DOI: 10.1017/s0007114522003269
  • Peer Reviewed / Open Access
• [Journal Article] The relationship between organ-tissue body composition and resting energy expenditure in prepubertal children (2018)
  • Author(s): Midorikawa Taishi、Hikihara Yuki、Ohta Megumi、Ando Takafumi、Torii Suguru、Sakamoto Shizuo、Tanaka Shigeho
  • Journal Title: European Journal of Clinical Nutrition Volume: in press Issue: 8 Pages: 1149-1154
  • DOI: 10.1038/s41430-018-0344-2
  • Peer Reviewed / Open Access
• [Journal Article] Lean soft tissue mass measured using dual-energy x-ray absorptiometry is an effective index for assessing change in leg skeletal muscle mass following exercise training. (2018)
  • Author(s): Midorikawa T, Ohta M, Torii S, Sakamoto S.
  • Journal Title: Journal of Clinical Densitometry Volume: ー Issue: 3 Pages: 394-398
  • DOI: 10.1016/j.jocd.2018.03.008
  • Peer Reviewed / Open Access
• [Journal Article] Body mass-to-waist ratio strongly correlates with skeletal muscle volume in children (2017)
  • Author(s): Ohta Megumi、Midorikawa Taishi、Hikihara Yuki、Sakamoto Shizuo、Kawakami Yasuo、Fukunaga Tetsuo、Kanehisa Hiroaki
  • Journal Title: PLOS ONE Volume: 12 Issue: 5 Pages: 1-13
  • DOI: 10.1371/journal.pone.0177155
  • Peer Reviewed / Open Access
• [Journal Article] Validity of segmental bioelectrical impedance analysis for estimating fat-free mass in children including overweight individuals. (2017)
  • Author(s): Ohta M, Midorikawa T, Hikihara Y, Masuo Y, Sakamoto S, Kawakami Y, Fukunaga T, Kanehisa H.
  • Journal Title: Applied Physiology, Nutrition, and Metabolis. Volume: 42 Issue: 2 Pages: 157-165
  • DOI: 10.1139/apnm-2016-0137
  • Peer Reviewed
• [Presentation] Predicting whole body and appendicular skeletal muscle volume using limb circumferences in Japanese prepubertal boys. (2020)
  • Author(s): Midorikawa T, Ohta M, Hikihara Y, Torii S, Sakamoto S.
  • Organizer: 25th Annual Congress of the European College of Sports Science
  • Int'l Joint Research
• [Presentation] The relationship between organ-tissue of body composition and resting energy expenditure in prepubertal children. (2018)
  • Author(s): Midorikawa T, Hikihara Y, Ohta M, Ando T, Torii S, Sakamoto S, Tanaka S.
  • Organizer: 11th International Symposium on IN VIVO BODY COMPOSITION STUDIES
  • Int'l Joint Research
• [Presentation] Lean soft tissue mass measured by dual-energy X-ray absorptiometry is an effective index for assessing change in leg skeletal muscle mass following exercise training. (2018)
  • Author(s): Midorikawa T, Ohta M, Torii S, Sakamoto S.
  • Organizer: 23th Annual Congress of the European College of Sports Science
  • Int'l Joint Research
• [Presentation] Can 3DPS Method Validly Estimate %Fat of Children? (2018)
  • Author(s): Ohta M, Midorikawa T, Hikihara Y, Shitara K, Torii S, Sakamoto S.
  • Organizer: 23th Annual Congress of the European College of Sports Science
  • Int'l Joint Research
• [Presentation] Organ-tissue resting metabolic rate in Japanese prepubertal children versus adults. (2017)
  • Author(s): Midorikawa T, Hikihara Y, Ohta M, Ando T, Torii S, Sakamoto S, Tanaka S.
  • Organizer: 4th international conference on Recent Advances and Controversies in Measuring Energy Metabolism
  • Int'l Joint Research