| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
There is little evidence what the diet and exercise in childhood will effect on adult. The purpose of this study was to investigate the long term effects of diet and exercise in childhood on metabolism related gene expression in skeletal muscle and white adipose tissue of adult mice.
Our results suggested that the long term effects of diet and exercise in childhood on the gene expression in skeletal muscle is about half compared to that in adipose tissue, that means there may be only a weak legacy effect on the gene expression in skeletal muscle. The environmental enrichment in childhood brought increase tendencies in physical activity and body temperature, but there was no effect in muscle strength. These data suggested that the further investigation is needed to create a more effective environment in childhood.
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