Neural mechanism of hierarchical categorization

• Project/Area Number: 16K01959
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Brain biometrics
• Research Institution: Niigata University
• Principal Investigator: Kawasaki Keisuke 新潟大学, 医歯学系, 准教授 (60511178)
• Research Collaborator: Suzuki Takafumi ; Matsumoto Narihisa
• Project Period (FY): 2016-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2018: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
• Keywords: カテゴリ認知 / 概念化 / 視覚認知 / 抽象化 / 階層構造 / 概念形成 / 階層性 / 霊長類 / 皮質脳波 / カテゴリー認知 / 認知脳科学 / 下側頭葉皮質 / 前頭葉 / 側頭葉 / 脳・神経

Outline of Final Research Achievements

Abstraction is a key computing underling our intelligent capacity such as thinking, inference and linguistic activity. However neuronal basis of the cognitive process is largely unknown mainly because a lack of an appropriate animal model which enable us to measure and manipulate the direct neural activity. In this project, thus we developed a hierarchal categorization task for monkeys. We show that two out of the two monkeys learned the hierarchal categorization in which the monkey has to explicitly classify the natural categories with three abstraction levels. We also investigated the neural representation of face and its subcategories. Neural activities were recorded by electrocorticogram, local field potential and multi-unit activity in inferior temporal cortex (ITC). The results suggest that the finer category clusters are heterogeneously distributed even outside their parent category cluster and dynamically increase heterogeneity along with the cortical processing in the ITC.

Academic Significance and Societal Importance of the Research Achievements

抽象的な概念を用いたカテゴリ認知は，ヒトの知的活動を支える基本的かつ重要な認知機能である.しかし，これまでカテゴリ認知における抽象化過程の神経メカニズムに関しては，適当な動物モデルが存在せず直接的な知見がなかった. 本研究課題ではサルにおいて三層の階層性をもつ階層カテゴリ課題を開発し，２頭中２頭の被験体において，学習が成立することを示すことに成功した．今後，脳活動計測を行い，概念形成の脳内メカニズムの検証を進めることが可能になった.

Research Products

• [Journal Article] Heterogeneous Redistribution of Facial Subcategory Information Within and Outside the Face-Selective Domain in Primate Inferior Temporal Cortex (2018)
  • Author(s): Miyakawa Naohisa、Majima Kei、Sawahata Hirohito、Kawasaki Keisuke、Matsuo Takeshi、Kotake Naoki、Suzuki Takafumi、Kamitani Yukiyasu、Hasegawa Isao
  • Journal Title: Cerebral Cortex Volume: 28 Issue: 4 Pages: 1416-1431
  • DOI: 10.1093/cercor/bhx342
  • Peer Reviewed / Open Access
• [Journal Article] Locally induced neuronal synchrony precisely propagates to specific cortical areas without rhythm distortion. (2018)
  • Author(s): Toda H, Kawasaki K, Sato S, Horie M, Nakahara K, Bepari AK, Sawahata H, Suzuki T, Okado H, Takebayashi H, Hasegawa I.
  • Journal Title: Scientific Reports Volume: - Issue: 1 Pages: 7678-7678
  • DOI: 10.1038/s41598-018-26054-8
  • Peer Reviewed / Open Access
• [Presentation] Anticipating of other's behavior on the basis of understanding other's false beliefs in rhesus monkeys (Macaca fuscata) (2018)
  • Author(s): Taketsugu Hayashi, Keisuke Kawasaki, Ryota Akikawa, Isao Hasegawa, Jun Egawa, Toshiyuki Someya, Atsuhiko Iijima
  • Organizer: 第41回日本神経科学大会
• [Presentation] Time-frequency representation of the responses for animate and inanimate objects in inferior temporal and medial dorsal prefrontal cortex (2018)
  • Author(s): Naohiro Okita, Keisuke Kawasaki, Yoshimichi Takahashi, Takeshi Matsuo, Takafumi Suzuki, Isao Hasegawa
  • Organizer: 第41回日本神経科学大会
• [Presentation] Neural activity during spelling the names of objects in the macaque prefrontal cortex (2018)
  • Author(s): Nanxi Liu, Kento Ohashi, Keisuke Kawasaki, Takafumi Suzuki, Takeshi Matsuo, Atsuhiko Iijima, Isao Hasegawa
  • Organizer: 第41回日本神経科学大会
• [Presentation] Time-frequency representation of the responses for animate and inanimate objects in inferior temporal and medial dorsal prefrontal cortex (2018)
  • Author(s): Okita N, Kawasaki K, Takahashi Y, Suzuki T, Matsuo T, Hasegawa I
  • Organizer: 第41回日本神経科学大会
  • Int'l Joint Research
• [Presentation] Category information in prefrontal and inferior temporal cortex for animate or inanimate categorization in macaques. (2017)
  • Author(s): Takahashi Y, Kawasaki K, Hongo T, Kulasekara M, Suzuki T, Iijima A, Matsuo T, Teramoto T, Hasegawa I.
  • Organizer: 第40回日本神経科学大会
  • Int'l Joint Research
• [Presentation] Modulation of value information coded in the lateral prefrontal cortex by decode neurofeedback with electrocorticographic (ECoG) signals. (2016)
  • Author(s): Tanaka S, Kawasaki K, Hasegawa I, Suzuki T, Sakagami M.
  • Organizer: Neuroscience2016
  • Place of Presentation: San Diego (U.S.A)
  • Year and Date: 2016-11-12
• [Presentation] Decoding recalled color imagery using ECoG signals in macaque inferior temporal and prefrontal cortices. (2016)
  • Author(s): Tanigawa H, Majima K, Takei R, Kawasaki K, Sawahata H, Nakahara K, Suzuki T, Kamitani Y, Hasegawa I.
  • Organizer: Neuroscience2016
  • Place of Presentation: San Diego (U.S.A)
  • Year and Date: 2016-11-12
• [Presentation] Relationships between the internal representations of convolutional neural network and the space, time and frequency domains of ECoG signals on macaque inferior temporal cortex. (2016)
  • Author(s): Date H, Kawasaki K, Ozay M, Hongo T, Hasegawa I, Okatani T.
  • Organizer: Neuroscience2016
  • Place of Presentation: San Diego (U.S.A)
  • Year and Date: 2016-11-12
• [Presentation] Directional influences through theta band activity between macaque inferior temporal and prefrontal cortices during memory retrieval. (2016)
  • Author(s): Sasaki H, Tanigawa H, Kawasaki K, Iijima A, Suzuki T, Hasegawa H.
  • Organizer: 第39回日本神経科学大会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-07-20
• [Presentation] Correspondence between the representations of convolutional neural networks and the activities in inferior temporal cortex measured by electrocorticography. (2016)
  • Author(s): Date H, Kawasaki K, Ozay M, Hongo T, Hasegawa I, Okatani T,
  • Organizer: 第39回日本神経科学大会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-07-20
• [Presentation] Direction-specific spectral shift of local field potentials in the rat visual cortics found by a combination of electrocorticogram and optogenetics. (2016)
  • Author(s): Toda H, Kawasaki K, Horie M, Nakahara K, Bepari K Asim, Sawahata H, Suzuki T, Takebayasi H, Hasegawa I.
  • Organizer: 第39回日本神経科学大会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-07-20
• [Presentation] Mismatch negativity in macaque auditory cortex is composed of several components of auditory stimuli. (2016)
  • Author(s): Suda Y, Tada M, Matsuo T, Kawasaki K, Suzuki T, Hasegawa I, Matsumoto K, Kasai K, Uka T.
  • Organizer: 第39回日本神経科学大会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-07-20
• [Presentation] Decoding the value related information from the ECoG signal recorded from the multiple areas of the prefrontal cortex. (2016)
  • Author(s): Tanaka S, Kawasaki K, Hasegawa I, Suzuki T, Sakagami M.
  • Organizer: 第39回日本神経科学大会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-07-20
• [Presentation] 皮質脳波法で見た下側頭葉皮質の階層的な視覚情報処理ネットワーク (2016)
  • Author(s): 川嵜圭祐
  • Organizer: 日本生体医工学会大会
  • Place of Presentation: 富山国際会議場・富山市民プラザ（富山県・富山市）
  • Year and Date: 2016-04-26