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The effect of increasing heart rate variability through biofeedback on baroreflex function

Research Project

Project/Area Number 16K04395
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Clinical psychology
Research InstitutionAichi Gakuin University

Principal Investigator

Sakakibara Masahito  愛知学院大学, 心身科学部, 教授 (10221996)

Research Collaborator HAYANO Junichiro  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2017: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywords心拍変動バイオフィードバック / 心拍変動 / 圧受容体反射 / 随伴性陰性変動 / バイオフィードバック / 自律神経機能 / 脳波
Outline of Final Research Achievements

The clinical utility of increasing heart rate variability (HRV) through biofeedback has been demonstrated for treatments of physical and mental disorders associated with autonomic nervous system dysregulation. Stimulation of the baroreflex (BR) system is considered a potential mechanism underlying this clinical effect. However, little research has addressed whether BR function is modulated by an increase in HRV. There is also growing evidence that higher levels of cortical activity are linked with higher cardiac autonomic tone. This study examined whether increasing HRV through biofeedback might improve BR sensitivity, and modify cortical activity, as assessed by contingent negative variation (CNV) in EEG. BR sensitivity significantly improved during the increasing HRV technique; the amplitude of CNV was also increased. These results suggest that increasing HRV may improve autonomic activity in homeostasis and also affect cortical activity involved in cognitive/attentional process.

Academic Significance and Societal Importance of the Research Achievements

バイオフィードバックによって心拍変動を増大させる技法はストレスに関連するさまざまな症状を低減し、これらに共通した抑うつや不安の改善に一定の成果をあげている。本研究は心拍変動の増大の効果を基礎的に検討し、この技法が自律神経機能を刺激するとともに皮質活動にも影響することを明らかにした。このことは、心拍変動増大が自律系ホメオスタシス機能を高め抑うつや不安を軽減することを示唆している。また、本研究は心拍変動の増大によって注意過程に関わる皮質活動の変化を観察した。抑うつや不安に関わる臨床場面ではネガティブな認知やバイアスを扱うことが多く、本研究の知見はこの種の認知過程に影響を及ぼす可能性を示唆している。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (11 results)

All 2019 2018 2017 2016

All Journal Article (6 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] 心拍変動増大に最適な呼吸は圧反射感度を高めるか?(第2報)-LF成分のピーク周波数にもとづいたペース呼吸の効果-2019

    • Author(s)
      榊原雅人・金田宗久・石田光男
    • Journal Title

      愛知学院大学心身科学研究所紀要「心身科学」

      Volume: 11 Pages: 17-22

    • NAID

      120006976707

    • Related Report
      2018 Annual Research Report
  • [Journal Article] 心拍変動の有用性-高周波および低周波成分に着目して-2019

    • Author(s)
      榊原雅人
    • Journal Title

      生理心理学と精神生理学

      Volume: 印刷中

    • NAID

      130007808351

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of negatively valenced words on deviant P3 during the three-stimulus oddball paradigm.2018

    • Author(s)
      Ishida, M., Kaneda, M., Akamine, A., & Sakakibara, M.
    • Journal Title

      Neuroscience Letters

      Volume: 683 Pages: 38-42

    • DOI

      10.1016/j.neulet.2018.06.001

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prospects for Using Heart Rate Variability in Biofeedback2018

    • Author(s)
      榊原雅人
    • Journal Title

      Japanese Journal of Biofeedback Research

      Volume: 45 Issue: 2 Pages: 79-85

    • DOI

      10.20595/jjbf.45.2_79

    • NAID

      130007548020

    • ISSN
      0386-1856, 2432-3888
    • Related Report
      2018 Annual Research Report
  • [Journal Article] 心拍変動増大に最適な呼吸は圧反射感度を高めるか?(第1報)-シーケンス法を用いた圧反射感度評価システムによる検討-2018

    • Author(s)
      榊原雅人・金田宗久・石田光男
    • Journal Title

      愛知学院大学心身科学研究所紀要「心身科学」

      Volume: 10 Pages: 27-34

    • NAID

      120006976716

    • Related Report
      2017 Research-status Report
  • [Journal Article] 心拍変動バイオフィードバックにおける 共鳴周波数検索について―安静時LFピーク周波数を利用した手続きの検討―2017

    • Author(s)
      榊原雅人・及川欧
    • Journal Title

      バイオフィードバック研究

      Volume: 印刷中

    • NAID

      130006855862

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Effect of paced breathing at the low-frequency peak of HRV on baroreflex sensitivity.2018

    • Author(s)
      Sakakibara, M., Kaneda, M., & Oikawa, O.
    • Organizer
      AAPB 49th Annual scientific meeting (Florida, USA)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] バイオフィードバック/ニューロフィードバックの臨床応用2018

    • Author(s)
      榊原雅人
    • Organizer
      第59回日本心身医学会ならびに学術講演会(名古屋)
    • Related Report
      2018 Annual Research Report
  • [Presentation] バイオフィードバックにおける心拍変動の可能性2018

    • Author(s)
      榊原雅人
    • Organizer
      第46回日本バイオフィードバック学会学術総会(東京)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 心拍変動増大が圧反射感度と随伴性陰性変動に及ぼす影響2018

    • Author(s)
      榊原雅人
    • Organizer
      日本心理学会第82回大会(仙台)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 心拍変動バイオフィードバック簡便法の検討 ―安静時LF周波数を利用したフィードバックの試行―2016

    • Author(s)
      榊原雅人・及川欧
    • Organizer
      第 44 回日本バイオフイードバック学会学術総会
    • Place of Presentation
      日本大学文理学部百周年記念館(東京都世田谷区)
    • Year and Date
      2016-06-11
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2020-03-30  

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