| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
Both clustering and oriented immobilization of enzymes on solid phase are critical for improving the enzyme-catalyzed chemical transformation of biosensors. Here, we have developed novel bio-nanocapusle-based scaffolds for clustering and oriented immobilization of enzymes. Furthermore, two-dimensional membrane scaffolds have also been developed for the oriented immobilization of biosensing molecules. These achievements could be applicable to develop the nanoblock scaffolds which could ordered-immobilize various biosensing molecules.
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