| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Some common diseases such as cancer and dermatitis occur as a result of the progression of essential protein (molecule) and cell abnormalities. In some disorders, progress may be mediated by hierarchical feedback between molecules (fast dynamics) and tissues (slow dynamics).
In this study, we investigate multi-scale dynamics of disease progression by mathematical models with hierarchical feedback. One of the expected outcomes of this study is to contribute to understanding dynamical processes of disease progression by using mathematical modeling, analyses, and numerical simulations.
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