Development of New Fluorination Reactions Aiming for Conversion of Raw Materials in Fluorination
| Project/Area Number |
16K05703
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Saga University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
小山田 重蔵 佐賀大学, 理工学部, 助教 (60525393)
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | フッ素化反応 / 超原子価ヨウ素 / 有機フッ素化合物 / 触媒反応 / 有機化学 |
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| Outline of Final Research Achievements |
In general, fluorination reactions need fluorine gas as a fluorine source. A safe and convenient fluorination reaction without fluorine gas is desirable. We have developed the safe and convenient fluorine reactions mediated by hypervalent iodine, where safer HF reagents are used as the fluorine source instead of dangerous fluorine gas. Furthermore, catalytic fluorination reactions using iodobenzenes have been developed. We are challenging the raw material conversion of fluorination reactions replacing conventional fluorination reactions using fluorine gas.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究で開発される技術は、従来のフッ素ガスを用いる方法では為し得なかった、安全かつ選択的フッ素化反応が進行させることができる優れた製造方法である。安全性と製造工程の簡便性、さらに重要なコスト面において、従来法をしのぐフッ素化技術である。これまでのフッ素化技術を一変させるフッ素化反応として産業界へ大きく貢献できる意義ある研究である。
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Report
(4 results)
Research Products
(32 results)
