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Development of non-toxic and color-tunable rare-earth nanoparticles and application of biomarkers

Research Project

Project/Area Number 16K05750
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Functional solid state chemistry
Research InstitutionMeijo University (2017-2018, 2022)
Shimane University (2016)

Principal Investigator

Nishiyama Katsura  名城大学, 理工学部, 教授 (40283725)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords発光バイオマーカー / 発光希土類 / 生体マーカー / イネ科 / ウリ科 / 発光希土類ナノ粒子 / 界面活性剤 / 界面活性剤鋳型法 / 4f-5d遷移 / 単子葉類 / 双子葉類 / 発光ナノ粒子 / 希土類酸化物 / 発光標識材料 / ナノ材料 / ナノバイオ / 自己組織化 / 希土類発光体
Outline of Final Research Achievements

About 15% of crops are lost during disease in the growing process. If we develop biolabeling where disease part emits by means of light irradiation, we can remove the diseased part in the early stage. We prevent the whole crop body is damaged by the disease. However, usual quantum dots contain toxic components such as Cd, which violates law for food safety. The nanoparticles is taken up from the root of the crop, rice for example, and travel to the crop parts such as root, stem and leaf in 30 min. The particles get into the deceased cell from the gate of the cell with 100 nm aperture. We have found that nanoparticles with d = 20 nm travel to the crop body irrespective of metal employed there.

Academic Significance and Societal Importance of the Research Achievements

農作物の収穫率向上は、食糧問題の解決ともあいまって、人類の早急な課題である。本研究が完成すれば、農作物の病害の早期発見、その切除に関わることになり、収穫率向上への直接的な解決策となる。なお既存の他の研究では、病害に対するバイオマーカーとして量子ドット等が使用されてきた。しかし量子ドットは毒劇物を使用しているので、農作物を対象とした研究には適さない。本研究は量子ドットを無害な金属に置換したものであり、社会的意義は極めて大きい。

Report

(4 results)
  • 2022 Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (13 results)

All 2018 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (10 results) (of which Int'l Joint Research: 5 results,  Invited: 4 results) Book (1 results)

  • [Journal Article] Synthesis of optically clear molecular organogels using phenol and a sulfosuccinic surfactant in various solvents with cyclic geometries2018

    • Author(s)
      K. Nishiyama, M. Kinoshita, T. Harada, Y. Katsumoto
    • Journal Title

      Journal of Molecular Liquids

      Volume: 268 Pages: 685-690

    • DOI

      10.1016/j.molliq.2018.07.091

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Optically Clear Molecular Organogels Comprising Phenol and Surfactants of Sulfosuccinic Acid Derivatives2017

    • Author(s)
      K. Nishiyama, M. Ehara, S. Katsube, T. Kaji
    • Journal Title

      Chem. Lett.

      Volume: 46 Issue: 9 Pages: 1361-1364

    • DOI

      10.1246/cl.170540

    • NAID

      130006067866

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Optical and thermal properties of self-assembly organogels comprising p-chlorophenol and a surfactant AOT2018

    • Author(s)
      Shuya Kato, Kyohei Tsukada, Norimitsu Mori, Narihiro Nagata, Tsuyoshi Yamaguchi, Katsura Nishiyama
    • Organizer
      Joint Conference of EMLG/JMLG Annual Meeting 2018 and 41st Symposium on Solution Chemistry of Japan “Understanding of Molecular Liquids and Its Extension to New Fields
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Analysis of transient hole burning spectra in organic solvents studied by molecular dynamics simulation2018

    • Author(s)
      Tsuyoshi Yamaguchi, Norio Yoshida, Katsura Nishiyama
    • Organizer
      Joint Conference of EMLG/JMLG Annual Meeting 2018 and 41st Symposium on Solution Chemistry of Japan “Understanding of Molecular Liquids and Its Extension to New Fields
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Stat Mech and materials synthesis: self-assembly organogel preparations and their applications to inclusive materials, and molecular origins of gelation processes2017

    • Author(s)
      K. Nishiyama
    • Organizer
      International Workshop on Stat-Mech of Liquids
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Organogel availability depending of solvophobicity of gelators in organic solvents: fibrous gel networks comprising phenol and sulfosuccinic acid derivatives2017

    • Author(s)
      K. Nishiyama, M. Kinoshita, E. Mamoru, S. Katsube, Y. Katsumoto, T. Kaji
    • Organizer
      Joint EMLG/JMLG Meeting 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] ゲル化剤の疎溶媒性相互作用の解明に基づく透明な分子オルガノゲルの創成2017

    • Author(s)
      西山 桂, 江原 守, 木下 勝, 嘉治寿彦, 勝本之晶
    • Organizer
      第40回溶液化学シンポジウム
    • Related Report
      2017 Research-status Report
  • [Presentation] 低分子ゲルマトリックス中におけるアップコンバージョンの光物性評価2017

    • Author(s)
      宇田進之輔・西山桂・勝本之晶・川井秀記
    • Organizer
      2017年光化学討論会
    • Related Report
      2017 Research-status Report
  • [Presentation] 低分子オルガノゲルの自己組織化構造を用いた光学物性及び熱物性制御2017

    • Author(s)
      西山 桂・森 識光・永田 晴寛
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Research-status Report
  • [Presentation] 溶液中における自己組織化を活かしたナノ構造体の創成と光学材料への展開2016

    • Author(s)
      西山 桂
    • Organizer
      第39回溶液化学シンポジウム
    • Place of Presentation
      産業技術総合研究所
    • Year and Date
      2016-11-09
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] ynthesis of emitting nanomaterials by using surfactant-assembly in the solution phase2016

    • Author(s)
      K. Nishiyama
    • Organizer
      Joint EMLG/JMLG Annual Meeting 2016
    • Place of Presentation
      Platanias - Chania, Crete, Greece
    • Year and Date
      2016-09-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 溶媒に顕著に依存するオルガノゲル物性~「出雲組子細工」にならったソフトマテリアル分子設計~2016

    • Author(s)
      西山 桂
    • Organizer
      研究会「分子を使った寄せ木細工」~自己組織化したソフトマテリアルが織りなす「かたち」と機能~
    • Place of Presentation
      島根大学
    • Year and Date
      2016-05-27
    • Related Report
      2016 Research-status Report
    • Invited
  • [Book] Molecular Aspects of Solvation Investigated using Statistical Mechanics2016

    • Author(s)
      N. Yoshida and K. Nishiyama
    • Total Pages
      17
    • Publisher
      Springer
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2024-01-30  

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