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Aggregation control and stacking diagnostics of nanoparticle structures in a dielectrophoretic assembly

Research Project

Project/Area Number 16K06388
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Measurement engineering
Research InstitutionTokyo Metropolitan University

Principal Investigator

Uchida Satoshi  首都大学東京, システムデザイン研究科, 准教授 (90305417)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords誘電泳動 / アセンブリ / ナノ粒子 / セルオートマトン / ピット / 陽子線描画技術 / 計測工学 / 計測システム
Outline of Final Research Achievements

The results obtained in this study are listed below.
(1) The pit-type three-dimensional dielectrophoretic device was numerically modeled to simulate particle behavior under various operating conditions. (2) We examined the substrate materials and process steps, and prototyped the actual device, and observed the dielectrophoretic collection behavior of standard particles and gold nanoparticles. (3) Changes in the amount of intra-pit aggregation of gold nanoparticles were investigated with respect to control parameters. (4) In addition to constructing an impedance measurement device, changes in the amount of lamination were examined theoretically. (5) The uniformity of particle adhesion was confirmed in the pit, and a different depth device was made on a trial basis. (6) The applied voltage and time were parameterized to derive the threshold of sticking and melting. Moreover, the stability of the control system was verified.

Academic Significance and Societal Importance of the Research Achievements

申請者が発展的に整備したDEPVMおよびDEPIMは、アセンブリとの同時操作が可能であり、迅速性と簡易性に優れている。また、ナノ粒子構造体の形成後では計測が困難な、経時的な凝集量や積層状態を定量化するため、作成デバイスを非破壊で評価できる。
一般にDEPアセンブリは、媒質中の界面分極効果により、様々な誘電粒子や金属粒子の操作が可能であり、その適用性は極めて広い。また、電気的な能動制御であるため、粒子形成状態の再現性も高い。将来的に本システムにおける堆積制御法と積層診断法が確立されれば、超伝導材料や生体有機材料を含む様々な粒状薄膜形成への展開も期待できる。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (35 results)

All 2019 2018 2017 2016

All Journal Article (6 results) (of which Peer Reviewed: 5 results) Presentation (28 results) (of which Int'l Joint Research: 5 results,  Invited: 4 results) Book (1 results)

  • [Journal Article] Chemical reaction process for magnetite nanoparticle synthesis by atmospheric-pressure DC glow-discharge electrolysis2018

    • Author(s)
      Yamazaki Yuya、Shirai Naoki、Nakagawa Yusuke、Uchida Satoshi、Tochikubo Fumiyoshi
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 57 Issue: 9 Pages: 096203-096203

    • DOI

      10.7567/jjap.57.096203

    • NAID

      210000149641

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 3次元誘電泳動デバイスにおける細胞挙動の数値解析2017

    • Author(s)
      佐藤健太,内田 諭,杤久保文嘉,円城寺隆治,脇坂嘉一
    • Journal Title

      静電気学会誌

      Volume: 41 Pages: 93-98

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Numerical Simulation of Gold Nanoparticles Dynamics in Dielectrophoretic Assembly2017

    • Author(s)
      中河原 僚介, 内田 諭, 澁谷 泰一, 西川 宏之
    • Journal Title

      IEEJ Transactions on Sensors and Micromachines

      Volume: 137 Issue: 4 Pages: 107-114

    • DOI

      10.1541/ieejsmas.137.107

    • NAID

      130005529934

    • ISSN
      1341-8939, 1347-5525
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Synthesis of magnetic nanoparticles by atmospheric-pressure glow discharge plasma-assisted electrolysis2017

    • Author(s)
      Naoki Shirai, Taketo Yoshida, Satoshi Uchida and Fumiyoshi Tochikubo
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 56 Issue: 7 Pages: 076201-076201

    • DOI

      10.7567/jjap.56.076201

    • NAID

      210000148009

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 高電界による液中微生物への動電作用2017

    • Author(s)
      内田 諭
    • Journal Title

      静電気学会誌

      Volume: 41 Pages: 259-263

    • Related Report
      2017 Research-status Report
  • [Journal Article] Metabolic Evaluation of Heat-Treated Yeast by Dielectrophoretic Velocimetry2016

    • Author(s)
      石田高広, 白井直機, 内田 諭, 杤久保文嘉
    • Journal Title

      IEEJ Transactions on Sensors and Micromachines

      Volume: 136 Issue: 12 Pages: 505-510

    • DOI

      10.1541/ieejsmas.136.505

    • NAID

      130005171121

    • ISSN
      1341-8939, 1347-5525
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 量子化学計算を用いた放電活性種と膜構成分子の反応解析2019

    • Author(s)
      戸田和希,内田 諭,杤久保文嘉
    • Organizer
      第66回応用物理学会春季講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 細胞膜内における活性酸素種輸送の分子動力学解析‐アンブレラサンプリングにおけるウィンドウ幅の影響‐2019

    • Author(s)
      太田隼人,内田 諭,杤久保文嘉
    • Organizer
      第66回応用物理学会春季講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 3次元誘電泳動デバイスを用いた腫瘍細胞分離における給電線の影響2019

    • Author(s)
      川村直弘, 内田 諭, 杤久保文嘉, 円城寺隆治, 脇坂嘉一, 高野雅代
    • Organizer
      平成31年電気学会全国大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 誘電泳動インピーダンス計測を用いた芽胞形成菌の電気特性評価2019

    • Author(s)
      堀 貴嗣, 内田 諭, 杤久保文嘉, 青木仁史
    • Organizer
      平成31年電気学会全国大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ピット型誘電泳動デバイスにおける交流電気浸透の効果の数値解析2019

    • Author(s)
      河嶋涼介, 内田 諭, 西川宏之
    • Organizer
      平成31年電気学会全国大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ピット型電極を用いた三次元誘電泳動における直流オフセット電圧の影響2019

    • Author(s)
      丸山大貴, 内田 諭, 加藤滉大, 西川宏之
    • Organizer
      平成31年電気学会全国大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 温度変化処理を施した食材付着菌のインピーダンス計測2018

    • Author(s)
      堀貴嗣,内田 諭,杤久保文嘉,青木仁史
    • Organizer
      2018年静電気学会全国大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 放電活性酸素種における膜透過特性の分子動力学シミュレーション2018

    • Author(s)
      太田隼人,内田 諭,杤久保文嘉
    • Organizer
      第77回応用物理学会秋季講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 3次元誘電泳動デバイスを用いた血中循環腫瘍細胞の分離検証 ―流路内速度分布の数値解析による最適分離条件の特定―2018

    • Author(s)
      川村直弘,内田 諭,杤久保文嘉,円城寺隆治,脇坂嘉一
    • Organizer
      第35回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] Numerical Investigation of Transport Characteristics of Reactive Oxygen Species in Biological Membrane with Molecular Dynamics2018

    • Author(s)
      Satoshi Uchida, Hayato Ohta, Ryota Imai and Fumiyoshi Tochikubo
    • Organizer
      15th International Conference on Flow Dynamics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Basic Transport Analysis of Reactive Oxygen Species in Biological Membrane with Molecular Dynamics2018

    • Author(s)
      Satoshi Uchida and Fumiyoshi Tochikubo
    • Organizer
      第28回日本MRS学会年次大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 腫瘍細胞分離デバイスにおける流量と電界の相関検証2018

    • Author(s)
      川村直弘,内田 諭,杤久保文嘉,円城寺隆治,脇坂嘉一
    • Organizer
      平成30年電気学会全国大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 生育期間変化時における酵母菌の誘電泳動速度と代謝状態の相関評価2018

    • Author(s)
      高松 聡,内田 諭,杤久保文嘉
    • Organizer
      平成30年電気学会全国大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 金ナノ粒子の三次元アセンブリにおける交流電気浸透流の影響2018

    • Author(s)
      中河原僚介,内田 諭,澁谷泰一,西川宏之
    • Organizer
      平成30年電気学会全国大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 相乗動電効果による金ナノ粒子の効率的三次元アセンブリ2018

    • Author(s)
      丸山大貴,内田 諭,澁谷泰一,西川宏之
    • Organizer
      平成30年電気学会全国大会
    • Related Report
      2017 Research-status Report
  • [Presentation] マイクロギャップリアクタ内における酵母増殖率のパルス幅及び電圧振幅依存性2017

    • Author(s)
      薄葉孝史,内田 諭,杤久保 文嘉
    • Organizer
      平成29年電気学会全国大会
    • Place of Presentation
      富山、日本
    • Year and Date
      2017-03-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 青色光照射酵母における誘電泳動速度と代謝状態の相関2017

    • Author(s)
      高松 聡,内田 諭,杤久保文嘉
    • Organizer
      平成29年電気学会全国大会
    • Place of Presentation
      富山、日本
    • Year and Date
      2017-03-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 三次元誘電詠動デバイス内の金ナノ粒子群に対する作用力の定量比較2017

    • Author(s)
      中河原僚介,内田 諭,澁谷泰一,西川宏之
    • Organizer
      平成29年電気学会全国大会
    • Place of Presentation
      富山、日本
    • Year and Date
      2017-03-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 放電活性種と膜構成分子の水中反応機構における分子動力学解析2017

    • Author(s)
      吉田健人,内田 諭,杤久保文嘉
    • Organizer
      第64回応用物理学会春季講演会
    • Place of Presentation
      横浜、日本
    • Year and Date
      2017-03-14
    • Related Report
      2016 Research-status Report
  • [Presentation] 3次元誘電泳動デバイスにおける血中細胞分離の数値シミュレーション2017

    • Author(s)
      佐藤健太,内田 諭,杤久保文嘉,円城寺隆治,脇坂嘉一
    • Organizer
      平成29年電気学会全国大会
    • Place of Presentation
      富山、日本
    • Related Report
      2016 Research-status Report
  • [Presentation] 誘電泳動アセンブリにおける金ナノ粒子ダイナミクスのシミュレーション2016

    • Author(s)
      中河原僚介,内田 諭,澁谷泰一,西川 宏之
    • Organizer
      第33回「センサ・マイクロマシンと応用システム」シンポジウム
    • Place of Presentation
      平戸、日本
    • Year and Date
      2016-10-24
    • Related Report
      2016 Research-status Report
  • [Presentation] Numerical Modeling of Plasma-Biomembrane Interactions with Molecular Dynamics2016

    • Author(s)
      Satoshi Uchida and Fumiyoshi Tochikubo
    • Organizer
      13th International Conference on Flow Dynamics
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2016-10-10
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 3次元誘電泳動分離デバイスにおける細胞挙動の数値解析2016

    • Author(s)
      佐藤健太,内田 諭,杤久保文嘉,円城寺隆治,脇坂嘉一
    • Organizer
      静電気学会全国大会
    • Place of Presentation
      桐生、日本
    • Year and Date
      2016-09-29
    • Related Report
      2016 Research-status Report
  • [Presentation] 多段式誘電泳動システムによる簡易細菌評価2016

    • Author(s)
      加藤英子,円城寺隆治,内田 諭
    • Organizer
      日本防菌防黴学会第43回年次大会
    • Place of Presentation
      品川、日本
    • Year and Date
      2016-09-26
    • Related Report
      2016 Research-status Report
  • [Presentation] 活性種照射条件に対する膜分子変性の系統的分子動力学解析2016

    • Author(s)
      吉田健人,内田 諭,杤久保文嘉
    • Organizer
      第77回応用物理学会秋季講演会
    • Place of Presentation
      新潟、日本
    • Year and Date
      2016-09-13
    • Related Report
      2016 Research-status Report
  • [Presentation] Numerical Analysis of Permeation Properties of Oxygen Active Species in Cell Membrane by Classical Molecular Dynamics2016

    • Author(s)
      Satoshi Uchida and Fumiyoshi Tochikubo
    • Organizer
      6th International Conference on Plasma Medicine
    • Place of Presentation
      Bratislava, Slovakia
    • Year and Date
      2016-09-04
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Brief evaluation of the membrane and metabolic characteristics of heat-injured yeast with dielectrophoretic velocimetry2016

    • Author(s)
      Satoshi Uchida, Takahiro Ishida, and Fumiyoshi Tochikubo
    • Organizer
      World Automation Congress 2016 Japan Satellite Session
    • Place of Presentation
      Himeji, Japan
    • Year and Date
      2016-08-06
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Numerical simulation of plasma-biomolecule interactions with molecular dynamics2016

    • Author(s)
      Satoshi Uchida
    • Organizer
      10th West Lake International Symposium on Magnetic Fusion & 12th Asia Pacific Plasma Theory Conference
    • Place of Presentation
      Hangzhou, China
    • Year and Date
      2016-05-09
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Book] "4.6 Numerical Modeling of Cell Membrane Transport Enhanced by Plasma Irradiation," Plasma Medical Science2019

    • Author(s)
      Satoshi Uchida, Annemie Bogaerts, Mohammed Yousfi, Hideki Motomura and Masafumi Jinno, (Ed.) Shinya Toyokuni, Yuzuru Ikehara, Fumitaka Kikkawa and Masaru Hori
    • Total Pages
      19
    • Publisher
      Academic Press
    • ISBN
      9780128150047
    • Related Report
      2018 Annual Research Report

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Published: 2016-04-21   Modified: 2020-03-30  

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