| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Small implant model made from Ti-6Al-4V was manufactured with powder bed selective laser melting method. It was implanted in femurs of IGS rats and the change in state of hard tissue formation around the implants had been observed. Active bone induction was observed around the model at diaphysial region of two weeks grown group after the implantation, and it was found that the originally created surface micro asperity in the additive manufacturing (AM) was bioactive. The bone induction was active around all of the surface of the implant: AM top surface, AM side surface and polished smooth surface. However, osteoconductivity was active on the polished surface and root of micro asperity of AM side surface.
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