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Double emulsion processing by using membranes with well-defined pore structures

Research Project

Project/Area Number 16K06835
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Properties in chemical engineering process/Transfer operation/Unit operation
Research InstitutionKogakuin University

Principal Investigator

Akamatsu Kazuki  工学院大学, 先進工学部, 准教授 (50451795)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords多孔膜 / ダブルエマルション / マイクロ流体デバイス / 膜乳化 / 化学工学 / マイクロ・ナノデバイス / 膜 / エマルション
Outline of Final Research Achievements

This study clearly demonstrated the permeation phenomena of double emulsion droplets through microporous membranes. Because it is impossible to observe in-situ the permeation behaviors in membrane pores, microchannels mimicking membrane pores were fabricated by standard soft lithography to enable the in-situ observation. Throughout the systematic experiments, three characteristic behaviors were observed: (a) passage into one channel without splitting; (b) division into two smaller components; and (c) stripping of the middle water phase of the double emulsion droplets into a smaller double emulsion droplet and a smaller water-in-oil single emulsion droplet. In addition, successful preparation of the functional microparticles with the use of the double emulsion droplets as templates were demonstrated.

Academic Significance and Societal Importance of the Research Achievements

液滴径が 50 μm より小さく,単分散なダブルエマルション液滴を調製する技術は,ほとんど研究開発が行われていない.我々は,単分散で液滴径の大きなダブルエマルションを従来のマイクロ流体デバイスを用いた技術で調製した後,膜で処理することでこれを達成する技術を有するが,膜内部のダブルエマルション分裂挙動に関する知見はほぼ得られていなった.本研究を通して,膜内部のダブルエマルション分裂挙動を可視化することに成功し,現象を理解することができた.この知見は,今後,機能性微粒子の調製などさまざまな場面で非常に役立つと考えられる.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (7 results)

All 2019 2018 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] A facile microencapsulation of phase change materials within silicone-based shells by using glass capillary devices2019

    • Author(s)
      Kazuki Akamatsu, Masaya Ogawa, Ryo Katayama, Keiko Yonemura, Shin-ichi Nakao
    • Journal Title

      Colloids and Surfaces A: Physicochemical and Engineering Aspects

      Volume: 567 Pages: 297-303

    • DOI

      10.1016/j.colsurfa.2019.01.076

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct Observation of Splitting in Oil-In-Water-In-Oil Emulsion Droplets via a Microchannel Mimicking Membrane Pores2017

    • Author(s)
      Kazuki Akamatsu, Koki Minezaki, Masumi Yamada, Minoru Seki, Shin-ichi Nakao
    • Journal Title

      Langmuir

      Volume: 33 Issue: 49 Pages: 14087-14092

    • DOI

      10.1021/acs.langmuir.7b03331

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] マイクロ流体デバイスを利用した相変化物質封入マイクロカプセルの開発2018

    • Author(s)
      赤松憲樹,小川真弥,片山涼,米村恵子,中尾真一
    • Organizer
      化学工学会第50回秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Microchannel mimicking membrane pores to observe splitting behaviors of double emulsion droplets2018

    • Author(s)
      Kazuki Akamatsu, Koki Minezaki, Masumi Yamada, Minoru Seki, Shin-ichi Nakao
    • Organizer
      15th International Conference on Microreaction Technology (IMRET15)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 膜細孔を模倣したマイクロチャネル内におけるダブルエマルションの分裂挙動2018

    • Author(s)
      赤松憲樹,峯崎航希,山田真澄,関実,中尾真一
    • Organizer
      化学工学会第83年会
    • Related Report
      2017 Research-status Report
  • [Presentation] Preparation of Double Emulsion Droplets with Thin Shells Using Membrane-Integrated Microfluidic Devices2016

    • Author(s)
      K. Akamatsu, S. Kanasugi, T. Mugitani, S. Nakao
    • Organizer
      14th International Conference on Microreaction Technology (IMRET14)
    • Place of Presentation
      Beijing, China
    • Year and Date
      2016-09-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Permeation of monodisperse double emulsion droplets through Shirasu Porous Glass (SPG) membranes2016

    • Author(s)
      K. Akamatsu, S. Kanasugi, T. Mugitani, S. Nakao
    • Organizer
      The 10th Conference of Aseanian Membrane Society (AMS 10)
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2016-07-26
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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