Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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Outline of Final Research Achievements |
Super-resolution fluorescence imaging is a technique to achieve observation at a higher spatial resolution than conventional optical microscopy. However, long-term time-lapse super-resolution observation at a fast frame rate still remains challenging. In this study we have developed a super-resolution imaging technique by which realistic super-resolved images are obtained with very low photodamage in live cells and intact biomolecules. By the present technique, we successfully achieve long-term super-resolution observation of cytoskeletons such as actin filaments in live cells.
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