| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Protein dynamics in an organism are important in elucidation of biological phenotype. However, intrinsic protein-protein interactions and the dynamics have never been detected, because recent structural researches have mainly used over-expressed proteins from model organisms. We made a new method using extract proteins from target organisms to elucidate biological phenotype from protein structure by the application of Hydrogen/Deuterium exchange and mass spectrometry, through developments of measurement tools and dedicated analytical software.
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