| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The revealed factors required for hydrogen production from propionate in Pelotomaculum thermopropionicum were membrane potential, ATP synthetase, and quinones. On the other hand, the two succinate dehydrogenases found in the genome of P. thermopropionicum proposed as responsible for succinate oxidation in the propionate metabolism, of which membrane binding SDH1 was proposed the major succinate dehydrogenase under a propionate oxidizing condition, whereas cytoplasmic SDH2 was predicted as a fumarate reductase under a non-propionate oxidizing condition. These results suggest that protein components localized in membrane responsible for the succinate oxidation are important for the propionate metabolism in P. thermopropionicum.
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