• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Physiological function and biosynthetic pathway of D-aspartate in marine macroalgae genus Sargassum

Research Project

Project/Area Number 16K07852
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Aquatic bioproduction science
Research InstitutionKitasato University

Principal Investigator

YOKOYAMA TAKEHIKO  北里大学, 海洋生命科学部, 講師 (60296431)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsヒジキ / 海藻 / ホンダワラ / D-アスパラギン酸 / ホンダワラ属 / ホンダワラ科 / 水産学 / 植物 / 蛋白質 / 酵素
Outline of Final Research Achievements

The presence of D-aspartate (D-Asp), a biologically rare amino acid, was evaluated in 38 species of marine macroalgae (seaweeds). Despite the ubiquitous presence of free L-Asp, free D-Asp was detected in only 5 species belonging to the Sargassaceae family of class Phaeophyceae (brown algae) but not in any species of the phyla Chlorophyta (green algae) and Rhodophyta (red algae).
All other members of Phaeophyceae, including 3 species classified into the section Teretia of Sargassaceae did not contain D-Asp. These results indicate that the presence of free D-Asp in marine macroalgae is restricted only to the Sargassaceae family, excluding the species in the section Teretia.

Academic Significance and Societal Importance of the Research Achievements

一般に生物に認められるL-アスパラギン酸というアミノ酸の鏡像異性体がD-アスパラギン酸(D-Asp)である。動物のD-Aspに対して,海藻のD-Aspの研究はまったく進んでいなかったが,本研究によって,海藻のD-Aspはホンダワラ科の海藻に限って存在していることが明らかになった。海藻のD-Aspの分布は環境的要因ではなく,進化の系統樹に沿った遺伝的な要因であることが示された。Aspはうま味成分の一つであることから,本研究成果は栄養学的な価値を有している。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (5 results)

All 2018 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] The presence of free D-aspartate in marine macroalgae is restricted to the Sargassaceae family2018

    • Author(s)
      Yokoyama Takehiko、Tokuda Masaharu、Amano Masafumi、Mikami Koji
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 82 Issue: 2 Pages: 268-273

    • DOI

      10.1080/09168451.2017.1423228

    • NAID

      120006547282

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Simultaneous determination of primary and secondary D- and L-amino acids by reversed-phase high-performance liquid chromatography using pre-column derivatization with two-step labelling method2017

    • Author(s)
      Yokoyama Takehiko、Tokuda Masaharu、Amano Masafumi、Mikami Koji
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 81 Issue: 9 Pages: 1681-1686

    • DOI

      10.1080/09168451.2017.1340090

    • NAID

      120006482573

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Asterionellopsis glacialisのD-アスパラギン酸2018

    • Author(s)
      横山雄彦
    • Organizer
      H30年度日本水産学会秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] なぜD-アスパラギン酸がヒジキに存在してウミトラノオに存在しないのか?2016

    • Author(s)
      横山雄彦
    • Organizer
      第12回D-アミノ酸学会学術講演会
    • Place of Presentation
      高知大学(高知県高知市)
    • Year and Date
      2016-09-14
    • Related Report
      2016 Research-status Report
  • [Presentation] ホンダワラ属海藻のD-アスパラギン酸2016

    • Author(s)
      横山雄彦
    • Organizer
      H28年度日本水産学会秋季大会
    • Place of Presentation
      近畿大学(奈良県奈良市)
    • Year and Date
      2016-09-09
    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi