Development of electron-deficient phosphine ligands and their application to catalysis
| Project/Area Number |
16K08161
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2016-10-21 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | トリアジン / π電子欠乏性 / リン配位子 / 金属錯体触媒 / 電子欠乏性ホスフィン配位子 / 1,3,5-トリアジン / 触媒反応 |
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| Outline of Final Research Achievements |
The purpose of this research is to develop highly active metal catalysts ligated by phosphines that are incorporated with triazines, because the triazines are electron-deficient and introduction of substituents on the triazine-ring for electronic tuning is facile. As a result of examining various metal catalysis, reactivity of catalytic reactions especially using tris(triazinyl)phosphines was improved. In addition, it was clarified that the reactivity changes depending on substituents of the triazine ring.
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| Academic Significance and Societal Importance of the Research Achievements |
金属触媒反応は，様々な化合物を作り出すために現代の有機合成化学には欠かせない．電子不足なトリス（トリアジニル）ホスフィンなどを用いて様々な金属触媒反応の検討を行ったところ，より活性な金属触媒を与えることを明らかとした．得られた成果は，金属触媒反応において学術的に重要な知見となると思われ，その波及効果が高いと期待される．また，金属触媒反応は様々な医薬品や材料物質を作りだすため，実用的な面で，その製造コストを削減できると思われる．
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Report
(4 results)
Research Products
(23 results)
