| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The genome of lentivirus including HIV is a positive sense single stranded RNA. The viral RNAs dimerize within virion connected each other by cis-RNA structure called dimer linkage structure (DLS). The reason, mechanism and process of dimerization are still unclear. In this research, I aimed to clarify the transition of a dynamic state and a morphology of lentiviral RNA in cell, from expression to virion packaging. This attempt will be achieved by the expansion of my research outcome so far. I planned this project for better understanding of the nature of lentiviruses.
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