Basic research for the development of the way how to allocate healthcare resources more efficiently and fairly
Project/Area Number |
16K08894
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical sociology
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Research Institution | Ritsumeikan University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
齋藤 信也 岡山大学, 保健学研究科, 教授 (10335599)
白岩 健 国立保健医療科学院, 保健医療経済評価研究センター, 主任研究官 (20583090)
村澤 秀樹 立命館大学, 生命科学部, 助教 (50770202)
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Project Period (FY) |
2016-04-01 – 2020-03-31
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Project Status |
Completed (Fiscal Year 2019)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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Keywords | 医療技術評価 / 医療資源配分 / 医療経済評価 / 資源配分の倫理 / 健康アウトカム評価 / 臨床試験 / 費用対効果 / 保険償還 / QOL評価 / マッピング / 健康効用値 / 費用効果分析 / 多基準決定分析 / MCDA / 患者選好 / 医療倫理 / QOL / 効用値 / 多基準意思決定分析(MCDA) / 生命倫理 / 政策意思決定 |
Outline of Final Research Achievements |
1. We translated and introduce the two major mapping guidance (MAPS Reporting Statement, ISPOR Task Force Report). The results of simultaneously measured scores/values by profile-based and preference-based instruments for prostate cancer patients were analyzed. We examined the utilization of assessing utility values in a cancer clinical trial. 2. To reveal the application-related issues for multi-criteria decision analysis (MCDA), we firstly identified important criteria by systematic review and secondly underwent some web-based surveys using the criteria for lay people and healthcare professionals. The surveys revealed the difference of priority and weight between for life-threatening disease and for non-life-threatening disease and that the linearity and distance’s equality between criteria-related categories and gained scores. 3. We gathered the reference information about the issue of productivity loss and data sources.
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Academic Significance and Societal Importance of the Research Achievements |
医療技術の評価において、従来の医療現場の有効性と安全性のエビデンスのみを重視する時代は終わり、効率性や平等性、経済性を加味した、社会的な価値の評価を積極的に行い、それに基づいて、医療の資源配分の意思決定を行う考え方が世界中に広がりつつある。しかるに、日本はその分野の研究と政策応用で後れを取っている。本研究の成果は、特に医療経済評価におけるQOL評価が有する課題や、医療資源配分の意思決定に用いられる多角的な価値基準を統合する方法の開発や進歩に大きく貢献するものであり、学術的、社会的意義は大きい。
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Report
(5 results)
Research Products
(85 results)
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[Journal Article] A multicenter survey of temporal changes in chemotherapy-induced hair loss in breast cancer patients.2019
Author(s)
Watanabe T, Yagata H, Saito M, Okada H, Yajima T, Tamai N, Yoshida Y, Takayama T, Imai H, Nozawa K, Sangai T, Yoshimura A, Hasegawa Y, Yamaguchi T, Shimozuma K, Ohashi Y
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Journal Title
PLoS One
Volume: 14
Issue: 1
Pages: e0208118-e0208118
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Health utility and health related quality of life of Japanese prostate cancer patients according to progression status measured using EQ-5D-5L and FACT-P2019
Author(s)
Murasawa H, Sugiyama T, Matsuoka Y, Okabe T, Hino A, Tanaka N, Sugimoto M, Oyama M, Fujimoto K, Horie S, Noto S, Shimozuma K
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Journal Title
Qual Lif Res
Volume: -
Issue: 9
Pages: 1-9
DOI
Related Report
Peer Reviewed
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[Journal Article] Effect of ruxolitinib therapy on the quality of life of Japanese patients with myelofibrosis.2018
Author(s)
Oritani K, Ohishi K, Okamoto S, Kirito K, Komatsu N, Tauchi T, Handa H, Saito S, Takenaka K, Shimoda K, Okada H, Amagasaki T, Wakase S, Shimozuma K, Akashi K
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Journal Title
Curr Med Res Opin
Volume: 34
Issue: 3
Pages: 531-537
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Cost-effectiveness analysis of the introduction of S-1 therapy for first-line metastatic breast cancer treatment in Japan: results from the randomized phase III SELECT BC trial.2017
Author(s)
Shiroiwa T, Fukuda T, Shimozuma K, Mouri M, Hagiwara Y, Kawahara T, Ohsumi S, Hozumi Y, Sagara Y, Ohashi Y, Mukai H
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Journal Title
BMC Cancer
Volume: 17
Issue: 1
Pages: 773-773
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Development of a Japanese version of the BREAST-Q and the traditional psychometric test of the mastectomy module for the assessment of HRQOL and patient satisfaction following breast surgery.2017
Author(s)
Saiga M, Taira N, Kimata Y, Watanabe S, Mukai Y, Shimozuma K, Mizoo T, Nogami T, Iwamoto T, Motoki T, Shien T, Matsuoka J, Doihara H
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Journal Title
Breast Cancer
Volume: 24(2)
Issue: 2
Pages: 288-298
DOI
NAID
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Long-term health status as measured by EQ-5D among patients with metastatic breast cancer: comparison of first-line oral S-1 and taxane therapies in the randomized phase III SELECT BC trial.2017
Author(s)
Shiroiwa T, Fukuda T, Shimozuma K, Mouri M, Hagiwara Y, Doihara H, Akabane H, Kashiwaba M, Watanabe T, Ohashi Y, Mukai H
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Journal Title
Qual Life Res
Volume: 26(2)
Issue: 2
Pages: 443-453
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Efficacy and safety of sequential use of everolimus in Japanese patients with advanced renal cell carcinoma after failure of first-line treatment with vascular endothelial growth factor receptor tyrosine kinase inhibitor: a multicenter phase II clinical trial.2017
Author(s)
Oyama M, Sugiyama T, Nozawa M, Fujimoto K, Kishida T, Kimura G, Tokuda N, Hinotsu S, Shimozuma K, Akaza H, Ozono S
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Journal Title
Jpn J Clin Oncol
Volume: -
Pages: 1-9
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] Analysis of cognitive function in elderly HER2-positive breast cancer patients receiving either trastuzumab monotherapy or trastuzumab plus chemotherapy as a postoperative adjuvant treatment: A cognitive function sub-study of a randomized, open-label, phase 3 clinical trial (RESPECT trial)2018
Author(s)
Takahashi M, Sawaki M, Hagiwara Y, Uemura Y, Kawahara T, Shimozuma K, Ohashi Y, Saito T, Baba S, Kobayashi K, Mukai H, Taira N
Organizer
2018 San Antonio Breast Cancer Symposium
Related Report
Int'l Joint Research
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[Presentation] Patient-reported outcomes with trastuzumab monotherapy versus trastuzumab plus standard chemotherapy as a postoperative adjuvant therapy in HER2-positive elderly breast cancer patients (RESPECT): A randomized, open-label, phase 3 clinical trial2018
Author(s)
Kobayashi K, Taira N, Sawaki M, Sagawa N, Baba S, Saito T, Kawahara T, Hagiwara Y, Uemura Y, Shimozuma K, Ohashi Y, Mukai H
Organizer
2018 San Antonio Breast Cancer Symposium
Related Report
Int'l Joint Research
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[Presentation] Subjective and objective assessment of efficacy of frozen gloves and socks to prevent nab-paclitaxel-induced peripheral neuropathy in patients with breast cancer2018
Author(s)
Yamashita T, Hattori M, Nakada T, Hayashi T, Kamei K, Tatsuya T, Nagao Y, Mase T, Wada M, Mizuno T, Shimozuma K, Iwata H, Yamaguchi T
Organizer
2018 San Antonio Breast Cancer Symposium
Related Report
Int'l Joint Research
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[Presentation] Economic evaluation guideline for pharmaceuticals and medical devices in Japan.2016
Author(s)
Fukuda T, Igarashi A, Ishida H, Ikeda S, Saito S, Sakamaki H, Shimozuma K, Shiroiwa T, Takura T, Tomita N, Noto S, Fukuda H, Moriwaki K, Moriyama Y, Akazawa M
Organizer
International Society for Phamacoeconomics and Outcomes Research (ISPOR) 7th Asia-Pacific Conference
Place of Presentation
Singapore (Singapore)
Year and Date
2016-09-04
Related Report
Int'l Joint Research
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[Presentation] 緩和医療と費用対効果2016
Author(s)
齋藤信也
Organizer
第21回日本緩和医療学会学術大会
Place of Presentation
京都国際会議場(京都府,京都市)
Year and Date
2016-06-18
Related Report
Invited
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[Presentation] 転移再発乳癌に対するタキサンとS-1の比較試験(SELECT-BC)のサブ解析と有害事象の経時的変化2016
Author(s)
斎藤 毅, 向井 博文, 原 文堅, 松原 伸晃, 高野 利実, 朴 英進, 井本 滋, 渡辺 隆紀, 西村 令喜, 下妻 晃二郎, 大橋 靖雄
Organizer
第24回日本乳癌学会学術総会
Place of Presentation
東京国際フォーラム(東京都,千代田区)
Year and Date
2016-06-17
Related Report
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[Book] 保健医療の経済評価2017
Author(s)
監訳:久繁哲徳、橋本秀樹
Total Pages
495
Publisher
篠原出版新社
ISBN
9784884123956
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