Fundamental study for the substance identified in photon counting mammography
Project/Area Number |
16K09015
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical Physics and Radiological Technology
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Research Institution | Kyoto College of Medical Science (2017-2018) Nagoya University (2016) |
Principal Investigator |
Kodera Yoshie 京都医療科学大学, 医療科学部, 研究員 (10124794)
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Co-Investigator(Kenkyū-buntansha) |
小山 修司 名古屋大学, 脳とこころの研究センター, 准教授 (20242878)
西出 裕子 岐阜医療科学大学, 保健科学部, 准教授 (80635730)
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Research Collaborator |
Mizutani Mitsuhiro
Watanabe Megumi
Yoshida Naoko
Yamamoto Shuichiro
Hashimoto Daisuke
Okada Masahiro
Nakajima Ai
Sasaki Mariko
Suzuki Reina
Kimura Hiroto
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Project Period (FY) |
2016-10-21 – 2019-03-31
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Project Status |
Completed (Fiscal Year 2018)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | フォトンカウンティング技術 / マンモグラフィ / 物質同定 / 実効原子番号 / コントラスト対雑音比 / 被曝低減 / ディジタルマンモグラフィ / 実効原子番号画像 / 乳腺含有率 / dense breast / フォトンカウンティング / X線 / 画像 / 癌 / 細胞・組織 |
Outline of Final Research Achievements |
In analog systems, high contrast images are necessary to identify breast cancer. However, in the digital system, high CNR (contrast-to-noise ratio) is required. A novel energy-resolved photon-counting mammography (ERPCM) is being developed using a cadmium zinc telluride detector. The purpose of this study is to examine whether to obtain the higher CNR image using higher tube voltage, and is to create a novel fusion medical image of anatomy and physics, and explore the clinical meaning of this image. It was suggested that there is the usefulness of using high tube voltage for thicker and dense breast. On the scatterplots, it could discriminate the tumor values from normal tissue values for each case by a case. And on the fusion images, by coloring to around 20% from the top of the scatter points, the tumors on the images which the same part was diagnosed as a tumor were colored.
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Academic Significance and Societal Importance of the Research Achievements |
連続スペクトルを持つX線のスペクトル情報の利用は、多くの医療関係者の望むところであり、現在種々の研究開発が行われているが、いまだその最終目的は達成されていない。本研究は、独自の解析方法を用いることで精度よく生体内の物質の同定に成功し、その可視化も実現している。今後、本手法を用いることで、これまでにはない新たな生体情報の取得が可能になり、画像診断の可能性の大きく広がることが期待できる。
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Report
(4 results)
Research Products
(32 results)
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[Journal Article] A novel mammographic fusion imaging technique: the first results of tumor tissues detection from resected breast tissues using energy-resolved photon counting detector2019
Author(s)
Mariko Sasaki, Shuji Koyama, Yoshie Kodera, Reina Suzuki, Hiroto Kimura, Hiroto Nishide, Mitsuhiro Mizutani, Megumi Watanabe, Naoko Yoshida, Hiroaki Hayashi, Natsumi Kimoto, Shuichiro Yamamoto, Daisuke Hashimoto, Masahiro Okada
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Journal Title
Proc. SPIE, Medical Imaging 2019: Physics of Medical Imaging
Volume: 10948
DOI
Related Report
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[Journal Article] Identification of breast tissue using the x-ray image measured with an energy-resolved cadmium telluride series detector based on photon-counting technique2018
Author(s)
Mariko Sasaki, Shuji Koyama, Yoshie Kodera, Reina Suzuki, Ai Nakajima, Hiroko Nishide, Mitsuhiro Mizutani, Megumi Watanabe, Naoko Yoshida, Hiroaki Hayashi, Tsutomu Yamakawa, Shuichiro Yamamoto, Daisuke Hashimoto, Masahiro Okada
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Journal Title
Proc. SPIE, 14th International Workshop on Breast Imaging (IWBI 2018)
Volume: 10718
DOI
Related Report
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[Journal Article] Development of energy-resolved photon-counting mammography with a cadmium telluride series detector to reduce radiation exposure and increase contrast-to-noise ratio using the high-energy X-rays2018
Author(s)
Reina Suzuki, Shuji Koyama, Yoshie Kodera, Ai Nakajima, Mariko Sasaki, Hiroto Kimura, Hiroaki Hayashi, Tsutomu Yamakawa, Shuichiro Yamamoto, Daisuke Hashimoto, Masahiro Okada
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Journal Title
Proc. SPIE, 14th International Workshop on Breast Imaging (IWBI 2018)
Volume: 10718
DOI
Related Report
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[Presentation] A novel mammographic fusion imaging technique: the first results of tumor tissues detection from resected breast tissues using energy-resolved photon counting detector2019
Author(s)
Mariko Sasaki, Shuji Koyama, Yoshie Kodera, Reina Suzuki, Hiroto Kimura, Hiroto Nishide, Mitsuhiro Mizutani, Megumi Watanabe, Naoko Yoshida, Hiroaki Hayashi, Natsumi Kimoto, Shuichiro Yamamoto, Daisuke Hashimoto, Masahiro Okada
Organizer
SPIE Medical Imaging, 2019
Related Report
Int'l Joint Research
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[Presentation] Identification of breast tissue using the x-ray image measured with an energy-resolved cadmium telluride series detector based on photon-counting technique2018
Author(s)
Mariko Sasaki, Shuji Koyama, Yoshie Kodera, Reina Suzuki, Ai Nakajima, Hiroko Nishide, Mitsuhiro Mizutani, Megumi Watanabe, Naoko Yoshida, Hiroaki Hayashi, Tsutomu Yamakawa, Shuichiro Yamamoto, Daisuke Hashimoto, Masahiro Okada
Organizer
The Fourteenth International Workshop on Breast Imaging
Related Report
Int'l Joint Research
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[Presentation] Development of energy-resolved photon-counting mammography with a cadmium telluride series detector to reduce radiation exposure and increase contrast-to-noise ratio using the high-energy X-rays2018
Author(s)
Reina Suzuki, Shuji Koyama, Yoshie Kodera, Ai Nakajima, Mariko Sasaki, Hiroto Kimura, Hiroaki Hayashi, Tsutomu Yamakawa, Shuichiro Yamamoto, Daisuke Hashimoto, Masahiro Okada
Organizer
The Fourteenth International Workshop on Breast Imaging
Related Report
Int'l Joint Research
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[Presentation] A proposed new image display method with high a contrast-to-noise ratio using energy-resolved photon-counting mammography with a CdTe-series detector2018
Author(s)
Reina SUZUKI, Shuji KOYAMA, Yoshie KODERA, Ai NAKAJIMA, Mariko SASAKI, Yoko IIDA, Fukiko ITO, Yumiko KOSHIBA, Tsutomu YAMAKAWA, Shuichiro YAMAMOTO, Daisuke HASHIMOTO, Masahiro OKADA
Organizer
SPIE Medical Imaging 2018
Related Report
Int'l Joint Research
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[Presentation] Identification and differentiation of resected breast tissue specimens using a cadmium telluride series photon-counting X-ray detector2017
Author(s)
Mariko Sasaki, Ai Nakajima, Akiko Ihori, Hiroko Nishide, Shuji Koyama, Tsutomu Yamakawa, Shuichiro Yamamoto, Masahiro Okada, Mitsuhiro Mizutani, Yoshie Kodera
Organizer
CARS 2017 31th Computer assisted radiology and surgery, Barcelona, Spain
Related Report
Int'l Joint Research
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[Presentation] Study of substance identification and effective atomic number visualization in mammography using photon-counting technique2017
Author(s)
Suzuki Reina, Shiori Tomita, Ai Nakajima, Akiko Ihori, Shuji Koyama, Tsutomu Yamakawa, Shuichiro Yamamoto, Masahiro Okada, Yoshie Kodera
Organizer
CARS 2017 31th Computer assisted radiology and surgery, Barcelona, Spain
Related Report
Int'l Joint Research
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