The study on the benefit of water intake for the prevention of cerebral infarction

• Project/Area Number: 16K09083
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Kyoto Koka Women's University
• Principal Investigator: Nishikawa Tomofumi 京都光華女子大学, 健康科学部, 教授 (20647945)
• Co-Investigator(Kenkyū-buntansha): 岡村 智教 慶應義塾大学, 医学部(信濃町), 教授 (00324567) ; 上羽 哲也 高知大学, 教育研究部医療学系臨床医学部門, 教授 (00314203) ; 宮松 直美 滋賀医科大学, 医学部, 教授 (90314145) ; 北条 雅人 京都大学, 医学研究科, 非常勤講師 (60372588)
• Research Collaborator: FUKUDA Shunichi
• Project Period (FY): 2016-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 脳卒中予防 / 水分摂取 / 予防医学

Outline of Final Research Achievements

We made database on patients with cerebral infarction (314 participants). We compared it with the data on healthy subjects (1013 subjects in the participants in the Kobe Orthopedic and Biomedical Epidemiologic Study (KOBE STUDY)) and found that the non-alcohol drink intake before the onset of the cerebral infarction in the patients with cerebral infarction was less than that in the healthy subjects. We presented these results in academic meetings and in an English-language journal.

Academic Significance and Societal Importance of the Research Achievements

本研究の一部の成果であるが、脳梗塞既往者は発症前の水分摂取量が健常者と比較して少なかったことが示唆された。この結果が脳血管疾患に携わる医療従事者がしばしば参考にする主要な脳血管疾患専門の英文学術誌に掲載された意義は大きく、今後、脳梗塞予防に対する日常的な水分摂取の推奨やこの分野の更なる研究の進展に繋がっていくことが予想される。

Research Products

• [Journal Article] Daily Habit of Water Intake in Patients with Cerebral Infarction before its Onset; Comparison with a Healthy Population: A Cross-sectional Study (2019)
  • Author(s): Tomofumi Nishikawa, Naomi Miyamatsu, Aya Higashiyama, Masato Hojo, Yoko Nishida, Shunichi Fukuda, Takumi Hirata, Kayoko Ichiura, Yoshimi Kubota, Sachimi Kubo, Tetsuya Ueba, Aya Kadota, Daisuke Sugiyama and Tomonori Okamura
  • Journal Title: Cerebrovascular Diseases Volume: 印刷中 Issue: 3-4 Pages: 1-8
  • DOI: 10.1159/000500075
  • Peer Reviewed / Open Access
• [Presentation] 健常者と脳梗塞既往者の水分摂取量の違い (2018)
  • Author(s): 西川 智文,宮松 直美, 東山 綾 , 北条 雅人, 西田 陽子, 福田 俊一, 一浦 嘉代子, 久保 佐智美 ,岡村 智教
  • Organizer: 第54回日本循環器病予防学会
• [Presentation] Difference in water intake between persons with a history of cerebral infarction and healthy persons: a cross sectional study (2018)
  • Author(s): Tomofumi Nishikawa, Naomi Miyamatsu, Aya Higashiyama, Masato Hojo, Yoko Nishida, Shunichi Fukuda, Takumi Hirata, Kayoko Ichiura, Yoshimi Kubota, Sachimi Kubo, Tetsuya Ueba, Aya Kadota, Daisuke Sugiyama and Tomonori Okamura
  • Organizer: The 11th European Public Health Conference
  • Int'l Joint Research
• [Presentation] 健常者と脳梗塞既往者の飲酒履歴の違い (2018)
  • Author(s): 西川 智文
  • Organizer: 52回日本アルコール・アディクション医学会学術総会
• [Presentation] DIFFERENCES IN DRINKING HISTORY BETWEEN HEALTHY PEOPLE AND PATIENTS WITH CEREBRAL INFARCTION (2018)
  • Author(s): Tomofumi Nishikawa
  • Organizer: ESBRA2017
  • Int'l Joint Research
• [Presentation] 健常日本人における水分摂取意識と摂取飲料の違い (2017)
  • Author(s): 西川 智文
  • Organizer: 第27回日本疫学会学術総会
  • Place of Presentation: ベルクラシック甲府
  • Year and Date: 2017-01-25