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Diagnosis and ablation of superior type fast-slow atrioventricular nodal reentrant tachycardia

Research Project

Project/Area Number 16K09418
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular medicine
Research InstitutionGunma University

Principal Investigator

Kaneko Yoshiaki  群馬大学, 大学院医学系研究科, 准教授 (60302478)

Co-Investigator(Kenkyū-buntansha) 中島 忠  群馬大学, 医学部附属病院, 講師 (40510574)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords房室結節リエントリー性頻拍 / アブレーション / 臨床 / 内科 / 循環器・高血圧 / 不整脈 / 頻拍症
Outline of Final Research Achievements

We investigate varieties of atypical atrioventricular nodal reentrant tachycardia (AVNRT) using a superior slow pathway (sup-SP). Among 18 patients of superior type fast-slow AVNRT, we found 4 patients with the tachycardia using a sup-SP extending superoanterior right atrial free wall along the tricuspid annulus, namely superoanterior type. Also, among 43 patient of apparent slow-fast AVNRT who underwent different atrial entrainment pacing, we found 4 patients (9%) of the tachycardia presenting atypical response during the pacing, who might include slow-fast AVNRT using a sup-SP as an antegrade limb.

Academic Significance and Societal Importance of the Research Achievements

本研究では、稀ではあるが新たな房室結節リエントリー性頻拍の一亜型の機序、診断及びアブレーション治療法を明らかにした。さらに、稀な房室結節伝導路であるsuperior slow pathwayの成因が、三尖弁輪右房自由璧に存在する房室輪の遺残の可能性があることを示唆した。多くの上室性頻拍はカテーテル治療によって根治可能となっているが、本研究により未知の頻拍の存在が明らかになることによってさらなるアブレーション治療の適応拡大、治療成績の向上が期待される。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (11 results)

All 2019 2018 2017 2016

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results) Presentation (8 results) (of which Int'l Joint Research: 4 results,  Invited: 2 results) Book (1 results)

  • [Journal Article] A case of atypical fast-slow atrioventricular nodal reentrant tachycardia utilizing a slow pathway extending to the superoanterior right atrium.2019

    • Author(s)
      Kaneko Y, Nakajima T, Iizuka T, Tamura S, Kurabayashi M.
    • Journal Title

      Int Heart J

      Volume: XX

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 通常のSlow pathwayをbystander pathwayとするsuperior type fast-slow 房室結節リエントリー性頻拍の1例.2018

    • Author(s)
      飯塚貴士、金古善明、中島忠、入江忠信、太田昌樹、飯島貴史、田村未央、田村峻太郎、齋藤章宏、倉林正彦
    • Journal Title

      臨床心臓電気生理

      Volume: 41 Pages: 233-243

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Presentation] How to Ablate Atypical AVNRT Utilizing Variant of Slow Pathways?2018

    • Author(s)
      Kaneko Y, et al
    • Organizer
      11th Asia Pacific Heart Rhythm Society Scientific Session(APHRS 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Application of V-A-A-V Response Immediately after Ventricular Induction/Entrainment to Discriminate Atypical Atrioventricular Nodal Reentrant Tachycardia from Atrial Tachycardia.2018

    • Author(s)
      Kaneko Y, et al
    • Organizer
      11th Asia Pacific Heart Rhythm Society Scientific Session(APHRS 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Electophysiological characteristics and catheter ablation of atypical fast-slow atrioventricular nodal reentrant tachycardia.2018

    • Author(s)
      Yoshiaki Kaneko
    • Organizer
      The 2018 International Congress on Electrocardiology (ICE 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Atypical fast-slow atrioventricular nodal reentrant tachycardia utilizing a slow pathway connected to the right atrial free wall along the tricuspid annulus.2018

    • Author(s)
      Yoshiaki Kaneko, Tadashi Nakajima, Akihiko Nogami, Yasuya Inden, Tetsuya Asakawa, Itsuro Morishima, Akira Mizukami, Tadanobu Irie, Takashi Iizuka, Shuntaro Tamura, Chihiro Ota, Yasunori Kanzaki, Kazuya Nakagawa, Makoto Suzuki, Masahiko Kurabayashi
    • Organizer
      American College of Cardiology's 67th Annual Scientific Session
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Recognition of Lower Common Pathway in the Atrioventricular Node in ATP-sensitive Supraventricular Tachycardia Originating from His-bundle Region.2017

    • Author(s)
      Kaneko Y, Nakajima T, Irie T, Iizuka T, Tamura S, Tamura M, Ota M, Saito A, Kurabayashi M
    • Organizer
      The 81th annual scientific meeting of the Japanese Circulation Society
    • Place of Presentation
      金沢
    • Year and Date
      2017-03-18
    • Related Report
      2016 Research-status Report
  • [Presentation] Atypical Superior Slow Pathway That Extends Anterolaterally Along the Tricuspid Annulus in Superior Type of Fast-slow Atrioventricular Nodal Reentrant Tachycardia.2017

    • Author(s)
      Kaneko Y, Nakajima T, Irie T, Iizuka T, Tamura S, Tamura M, Ota M, Saito A, Kurabayashi M
    • Organizer
      The 81th annual scientific meeting of the Japanese Circulation Society
    • Place of Presentation
      金沢
    • Year and Date
      2017-03-18
    • Related Report
      2016 Research-status Report
  • [Presentation] Electroanatomically-estimated localization of superior slow pathway in superior type of fast-slow atrioventricular nodal reentrant tachycardia.2016

    • Author(s)
      Shuntaro Tamura, Yoshiaki Kaneko, Tadashi Nakajima, Tadanobu Irie, Takashi Iizuka, Masahiko Kurabayashi, Osamu Igawa
    • Organizer
      ESC Congress 2016
    • Place of Presentation
      Roma
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
  • [Presentation] Atypical slow-fast atrioventricular nodal reentrant tachycardia incorporating “superior” slow pathway: a role of atrial differential entrainment pacing.2016

    • Author(s)
      Iizuka T, Kaneko Y, Nakajima T, Nakahara S, Irie T, Ota M, Iijima T, Tamura M, Tamura S, Saito A, Kurabayashi M
    • Organizer
      Heart Rhythm 2016
    • Place of Presentation
      San Farancisco
    • Year and Date
      2016-05-05
    • Related Report
      2016 Research-status Report
  • [Book] Catheter ablation: acurrent apporach on cardiac arrhythmias2018

    • Author(s)
      Kaneko Y
    • Total Pages
      390
    • Publisher
      Sprinder
    • Related Report
      2018 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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