| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The present study found that Aβ accumulation in cognitively normal research participants with subjective cognitive decline (SCD) might be predicted by the score change from immediate recall to delayed recall of the logical memory, whereas no significant differences were observed between Aβ-positive and negative SCD groups. Also, subjective memory decline correlated with verbal fluency and amotivation in Aβ-negative individuals with SCD.
Disclosing amyloid status to SCD did not cause significant long-term psychological risks. However, our findings suggested that those who fill criteria of SCD will include a possible high-risk subgroup for exacerbated distress after learning their negative amyloid PET results. Participants with high levels of anxiety before enrolment were more likely to have test-related distress one year after learning their amyloid negative results.
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