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Automatic evaluation for anatomical landmark and prediction for renal function in robotic-assisted partial nephrectomy

Research Project

Project/Area Number 16K10278
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKobe University

Principal Investigator

Takahashi Satoru  神戸大学, 医学研究科, 非常勤講師 (40311758)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
KeywordsCT / 低エネルギーCT / 3D / 腎がん / 術前シミュレーション / 低エネルギーCT撮像 / dual energy CT / ロボット支援腎部分切除術 / 画像診断 / ロボット支援手術
Outline of Final Research Achievements

Robotic-assisted partial nephrectomy, which is now covered by health-insurance, enables meticulous control of the tiny vessels. Thus, it has been growing interest and demands for preoperative non-invasive simulation with radiological imagings.We have established low-energy CT using low kVp X-ray tube for depicting intra-parenchymal branches of the renal vein on CT angiography.In addition, detailed analysis of small venous tumor thrombus is also vital for patients’ prognosis. We also introduced low energy CT using low keV virtual mononergertic imaging for visualizing tiny tumor thrombus in the sinus branches of the renal vein.

Academic Significance and Societal Importance of the Research Achievements

近年の機器の進歩により臨床応用が可能となったロボット支援腎部分切除術と、低エネルギーCTという二つの別々の技術を融合させることで、新しい術前診断の可能性について示すことができた。
最新の手術技術の進歩は、低侵襲化が進むが故に、治療前のシミュレーションの重要性がますます高まってきており、新しい治療技術を広く安全に施行するために外科医を支える技術開発を行うことができたと考える。この手法により、多くのロボット支援腎部分切除術を受ける患者が、安全かつ有用な低侵襲治療を受けることができるようになったと考える。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (22 results)

All 2019 2018 2017 2016

All Journal Article (8 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 8 results,  Open Access: 3 results) Presentation (14 results) (of which Int'l Joint Research: 14 results)

  • [Journal Article] Four-Dimensional Computed Tomography Evaluation of Condylar Movement in a Patient With Temporomandibular Joint Osteoarthritis2018

    • Author(s)
      Akashi Masaya、Hasegawa Takumi、Takahashi Satoru、Komori Takahide
    • Journal Title

      Journal of Oral and Maxillofacial Surgery

      Volume: 76 Issue: 2 Pages: 304-313

    • DOI

      10.1016/j.joms.2017.10.012

    • NAID

      120006541952

    • Related Report
      2018 Annual Research Report 2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Quantification of Cisplatin Using a Modified 3-Material Decomposition Algorithm at Third-Generation Dual-Source Dual-Energy Computed Tomography: An Experimental Study2018

    • Author(s)
      Sofue K., Itoh T., Takahashi S., Schmidt B., Shimada R., Negi N., Sugimura K., Murakami T.
    • Journal Title

      Investigative radiology

      Volume: 11 Issue: 11 Pages: 673-680

    • DOI

      10.1097/rli.0000000000000491

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Axial four-dimensional computed tomographic images to analyze crosswise differences in protrusive condylar movement in patients who underwent mandibulectomy and free flap reconstruction2017

    • Author(s)
      Akashi Masaya、Sekitani Toshinori、Ohtsuki Yumi、Kakei Yasumasa、Kusumoto Junya、Hasegawa Takumi、Maeda Michinori、Negi Noriyuki、Hashikawa Kazunobu、Shibuya Yasuyuki、Takahashi Satoru、Komori Takahide
    • Journal Title

      Journal of Cranio-Maxillofacial Surgery

      Volume: 45 Issue: 11 Pages: 1778-1783

    • DOI

      10.1016/j.jcms.2017.08.025

    • NAID

      120006373831

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Advantages of 70-kV CT Angiography for the Visualization of the Adamkiewicz Artery: Comparison with 120-kV Imaging2017

    • Author(s)
      Shimoyama S.、Nishii T.、Watanabe Y.、Kono A.K.、Kagawa K.、Takahashi S.、Sugimura K.
    • Journal Title

      American Journal of Neuroradiology

      Volume: 38 Issue: 12 Pages: 2399-2405

    • DOI

      10.3174/ajnr.a5372

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Application of dual-energy CT to suppression of metal artefact caused by pedicle screw fixation in radiotherapy: a feasibility study using original phantom2017

    • Author(s)
      Wang Tianyuan、Ishihara Takeaki、Kono Atsushi、Yoshida Naoki、Akasaka Hiroaki、Mukumoto Naritoshi、Yada Ryuichi、Ejima Yasuo、Yoshida Kenji、Miyawaki Daisuke、Kakutani Kenichiro、Nishida Kotaro、Negi Noriyuki、Minami Toshiaki、Aoyama Yuuichi、Takahashi Satoru、Sasaki Ryohei
    • Journal Title

      Physics in Medicine & Biology

      Volume: 62 Issue: 15 Pages: 6226-6245

    • DOI

      10.1088/1361-6560/aa7d7f

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The differences between bisecting and off-center cuts of the aortic root: The three-dimensional anatomy of the aortic root reconstructed from the living heart.2017

    • Author(s)
      Mori S, Anderson RH, Tahara N, Izawa Y, Toba T, Fujiwara S, Shimoyama S, Watanabe Y, Nishii T, Kono AK, Takahashi S, Hirata KI
    • Journal Title

      Echocardiography

      Volume: 印刷中 Issue: 3 Pages: 453-461

    • DOI

      10.1111/echo.13468

    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tailored Duration of Contrast Material Injection in High-Pitch Computed Tomographic Aortography With a Double-Level Test Bolus Method2017

    • Author(s)
      Nishii Tatsuya、Watanabe Yoshiaki、Shimoyama Shinsuke、Kono Atsushi K.、Sofue Keitaro、Mori Shumpei、Takahashi Satoru、Sugimura Kazuro
    • Journal Title

      Investigative Radiology

      Volume: 52 Issue: 5 Pages: 274-280

    • DOI

      10.1097/rli.0000000000000340

    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Four-dimensional noise reduction using the time series of medical computed tomography datasets with short interval times: a static-phantom study2016

    • Author(s)
      Nishii T, Kono AK, Tani W, Suehiro E, Negi N, Takahashi S, Sugimura K.
    • Journal Title

      PeerJ

      Volume: - Pages: e1680-e1680

    • DOI

      10.7717/peerj.1680

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Reassessment of the ability of renal CE-CT for avoiding pathological upstaging of clinical T1 to pathological T3 renal cancer in the era of robotic partial nephrectomy2019

    • Author(s)
      Takahashi S, Ueno Y, Sofue K, Negi N, Kagawa K, Tanaka U
    • Organizer
      European Congress of Radiology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Low energy imaging for depicting renal venous tumor thrombus on multi-phasic contrast-enhanced dual-energy CT with 3rd generation dual-source CT scanner2019

    • Author(s)
      Takahashi S, Itoh T, Ueno Y, Negi N, Kagawa K, Sofue K, Tanaka U< Kusaka A, Murakami T
    • Organizer
      European Congress of Radiology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] New and Updated Topics in Targeted Therapies for the Treatment of Advanced and Metastatic Renal Cell Carcinoma: What Radiologists Should Know.2018

    • Author(s)
      Ueno Y, Takahashi S, Sofue K, Tanaka, U, Tamada T, Murakami T.
    • Organizer
      Radiological Society of North America
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] What Radiologists Need to Focus on Renal Imaging for Preventing Pathological Upstaging of Clinical T1 to Pathological T3 Renal Cancer Managed by Partial Nephrectomy.2018

    • Author(s)
      Takahashi S, Ueno Y, Negi N, Kagawa K, Tanaka U, Murakami T.
    • Organizer
      Radiological Society of North America
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] All roads lead to Rome: Which scanning parameter is optimal for non-contrast body CT?2018

    • Author(s)
      Takahashi S, Itoh T, Negi N, Kusaka A
    • Organizer
      European Congress of Radiology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optimization of virtual monoenergetic imaging of dual-energy unenhanced body CT at 3rd generation dual-source dual-energy CT scanner: Phantom study2018

    • Author(s)
      Takahashi S, Itoh T, Negi N, Kusaka A
    • Organizer
      European Congress of Radiology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optimization of virtual monoenergetic imaging of dual-energy unenhanced body CT at 3rd generation dual-source dual-energy CT scanner: Phantom study2018

    • Author(s)
      S. Takahashi, T. Itoh, N. Negi, A. Kusaka
    • Organizer
      European congress of radiology 2018
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] All roads lead to Rome: Which scanning parameter is optimal for noncontrast body CT?2018

    • Author(s)
      S. Takahashi, T. Itoh, N. Negi, A. Kusaka
    • Organizer
      European congress of radiology 2018
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Is nephrographic phase essential in multi-phasic renal dynamic contrast enhanced dual-energy CT? Usefulness of low-keV mononergetic images for excretory phase2017

    • Author(s)
      S. Takahashi, N. Negi, W. Tani, K. Kagawa, T. Sekitani, E. Suehiro, T. Itoh, U. Tanaka, Y. Ueno
    • Organizer
      European Congress of Radiology
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2017-03-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Minimum-phase renal dynamic CT for the comprehensive preoperative assessment of robotic partial nephrectomy using 3rd generation dual-source dual-energy CT2017

    • Author(s)
      W. Tani, S. Takahashi, U. Tanaka, Y. Ueno, K. Kagawa, N. Negi, A. Kusaka, T. Itoh, K. Sugimura;
    • Organizer
      European Congress of Radiology
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2017-03-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Quantification of Cisplatin Concentration by using Material Decomposition Algorithm at 3rd Generation Dual Source Dual-Energy CT: An Experimental Phantom Study2017

    • Author(s)
      K. Sofue, T. Itoh, R. Shimada, T. Nishitani, N. Negi, K. Sugimura, Satoru Takahashi
    • Organizer
      Radiological Society of North America 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Does Split-Bolus Injection Truly Influence the Ability of Renal and Urinary Lesion Detection at CT Urography? Multi-Center Prospective Randomized Comparison between Split-Bolus and Single-Bolus Injection Techniques2017

    • Author(s)
      Satoru Takahashi, K. Kitajima, K. Sofue, U. Tanaka, K. Sugimura, Y. Yamashita, Y. Ueno, T. Matsuura, M. Takeuchi, M. Matsuki, N. Marugami, H. Juri, T. Yoshizako, Y. Honda, T. Namimoto, T. Kashimura, A. Nambu
    • Organizer
      Radiological Society of North America 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Low-kV CT Can Reduce the Frequency of Acute Adverse of Intravenous Iodine Contrast Medium.2016

    • Author(s)
      Maebayashi T, Takahashi S, Nishii T, Kono A, Negi N, Kagawa K, Suehiro E, Tani W, Sekitani T, Kawamitsu H, Sugimura K.
    • Organizer
      Radiological Society of North America
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Is nephrographic phase essential in multi-phasic dynamic contrast enhanced dual-energy CT for the preoperative assessment of partial nephrectomy?2016

    • Author(s)
      Takahashi S, Negi N, Kagawa K, Sekitani T, Tani W, Suehiro E, Tanaka U, Sugimura K.
    • Organizer
      European Society of Uroradiology
    • Place of Presentation
      Bordeaux, France
    • Year and Date
      2016-09-15
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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