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Experimental evaluation of postmortem enhanced CT image and histopathology

Research Project

Project/Area Number 16K10290
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionHokkaido University

Principal Investigator

Hyodoh Hideki  北海道大学, 医学研究院, 准教授 (30306154)

Co-Investigator(Kenkyū-buntansha) 的場 光太郎  北海道大学, 医学研究院, 講師 (00466450)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2017: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords死後造影CT / 動物実験 / 死後画像 / 法医放射線 / 放射線診断 / 死後画像診断 / 死後CT / 死後造影 / 肺血栓塞栓症 / 急性冠症候群 / 外傷 / 内因死 / 外因死 / CT / 死後変化 / カダバートレーニング / 溺水
Outline of Final Research Achievements

We evaluate the influence of infusion on cadaver lung, and to evaluate the mechanism of increasing lung density in postmortem CT. Comparing among the antemortem, and 80 ml injection and 160 ml injection groups, the lung density was relatively increasing after saline injection. The 160 ml injection group presented statistically increased lung density compared with antemortem and the 80 ml injection group. From segmented volume data analysis, the highly edematous lung area was statistically increasing; in contrast, the lung volume was not changed after saline injection. Therefore, depending on the infusion volume, the lung density increases, the aerated lung volume decreases, and the edematous lung volume increases in postmortem CT.

Academic Significance and Societal Importance of the Research Achievements

死後造影では、引き続き解剖が実施される場合に肺重量が影響を受けるため、死因判定に一定程度の影響が生じることが明らかとなった。動物実験を通じて、肺重量が増加する現象、肺重量を増加させない輸液投与量を明らかにした。
上記投与量を上限とした造影法によって、解剖前でも肺重量増加を生じさせない造影法を確立することができ、高い正診率で死後造影CTを実施可能となった。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (20 results)

All 2018 2017 2016 Other

All Int'l Joint Research (2 results) Journal Article (7 results) (of which Peer Reviewed: 7 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (8 results) (of which Int'l Joint Research: 8 results,  Invited: 2 results) Book (1 results) Remarks (2 results)

  • [Int'l Joint Research] New Mexico univ. OMI(米国)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Azienda Ospedaliera di Perugia(Italy)

    • Related Report
      2017 Research-status Report
  • [Journal Article] Lung weight estimation with postmortem CT in forensic cases2018

    • Author(s)
      Matoba Kotaro、Hyodoh Hideki、Ishida Lisa、Murakami Manabu、Matoba Tomoko、Saito Atsuko、Okuya Nahoko、Almansoori Sahar、Fujita Emi、Yamase Mayumi、Shao Minyo、Jin Shigeki
    • Journal Title

      Legal Medicine

      Volume: 35 Pages: 61-65

    • DOI

      10.1016/j.legalmed.2018.09.007

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Freezing preparation for macroscopic forensic investigation in putrefied brain2017

    • Author(s)
      Matoba K, Hyodoh H, Murakami M, Matoba T, Saito A, Feng F, Jin S
    • Journal Title

      Legal Medicine

      Volume: 26 Pages: 6-10

    • DOI

      10.1016/j.legalmed.2017.01.005

    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimating normal lung weight measurement using postmortem CT in forensic cases.2017

    • Author(s)
      Matoba K, Hyodoh H, Murakami M, Saito A, Matoba T, Ishida L, Fujita E, Yamase M, Jin S
    • Journal Title

      Legal Medicine

      Volume: 29 Pages: 77-81

    • DOI

      10.1016/j.legalmed.2017.10.014

    • NAID

      120006406689

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Experimental evaluation of freezing preparation for the macroscopic inspection in putrefied brain.2017

    • Author(s)
      Hyodoh H, Matoba K, Murakami M, Matoba T, Saito A, Feng F, Jin S.
    • Journal Title

      Legal Medicine

      Volume: 24 Pages: 19-23

    • DOI

      10.1016/j.legalmed.2016.10.009

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Time-related change evaluation of the cerebrospinal fluid using postmortem CT.2016

    • Author(s)
      Morikawa K, Hyodoh H, Matoba K, Mizuo K, Okazaki S, Watanabe S.
    • Journal Title

      Legal Medicine

      Volume: 22 Pages: 30-35

    • DOI

      10.1016/j.legalmed.2016.07.010

    • NAID

      120006337752

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Experimental drowning lung images on postmortem CT - Difference between sea water and fresh water.2016

    • Author(s)
      Hyodoh H, Terashima R, Rokukawa M, Shimizu J, Okazaki S, Mizuo K, Watanabe S.
    • Journal Title

      Legal Medicine (Tokyo)

      Volume: 19 Pages: 11-15

    • DOI

      10.1016/j.legalmed.2016.01.006

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Postmortem computed tomography findings in the thorax - Experimental evaluation.2016

    • Author(s)
      Hyodoh H, Shimizu J, Rokukawa M, Okazaki S, Mizuo K, Watanabe S.
    • Journal Title

      Legal Medicine (Tokyo)

      Volume: 19 Pages: 96-100

    • DOI

      10.1016/j.legalmed.2015.07.015

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Forensic Investigation of Postmortem Process Evaluated by GC/MS and CT.2018

    • Author(s)
      Yamase M, Hyodoh H, Matoba K, Matoba K, Jin S
    • Organizer
      10th International Symposium Advances in Legal Medicine
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Estimating normal lung weight measurement using postmortem CT in forensic cases.2018

    • Author(s)
      Matoba K, Hyodoh H, Ishida L
    • Organizer
      24th Congress of the International Academy of Legal Medicine (IALM)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Forensic Radiology in Japan2018

    • Author(s)
      Hyodoh H
    • Organizer
      7th congress of the International Society of Forensic Radiology and Imaging (ISFRI)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Lung weight estimation with postmortem CT in forensic autopsy cases.2018

    • Author(s)
      Ishida L, Hyodoh H, Matoba K.
    • Organizer
      24th Congress of the International Academy of Legal Medicine (IALM)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] An experimental evaluation of intermittent breathing in the appearance of drowning lung on postmortem CT2017

    • Author(s)
      Hyodoh H, Matoba K, Murakami M, Saito A, Matoba T, Fung F, Jin S
    • Organizer
      6th Congress of the International Society of Forensic Radiology and Imaging
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Forensic Investigation of Postmortem Process Evaluated by GC/MS and CT2017

    • Author(s)
      F.Feng, H Hyodoh, K,Matoba, S, Jin
    • Organizer
      10th International Symposium Advances in Legal Medicine
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Practical and education for forensic radiology in Japan2016

    • Author(s)
      Hyodoh H, Matoba K
    • Organizer
      2nd International Symposium of the Education Center for Forensic Pathology and Science
    • Place of Presentation
      長崎大学 良順会館(長崎県長崎市)
    • Year and Date
      2016-11-19
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Drowning lung CT patterns; experimental evaluation2016

    • Author(s)
      Hyodoh H, Terashima R, Rokukawa M, Shimizu J, Okazaki S, Mizuo K, Watanabe S
    • Organizer
      5th Congress of The International Society of Forensic Radiology and Imaging
    • Place of Presentation
      Amsterdam, Holland
    • Year and Date
      2016-05-12
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Book] 臨床法医学入門2017

    • Author(s)
      美作 宗太郎、山田 典子
    • Total Pages
      232
    • Publisher
      明石書店
    • ISBN
      9784750346007
    • Related Report
      2017 Research-status Report
  • [Remarks] POSTMORTEM IMAGING INTERPRETATION GUIDELINE

    • Related Report
      2017 Research-status Report
  • [Remarks] per l'interpretazion immagini acquisite

    • URL

      http://cdicenter.med.hokudai.ac.jp/dist/docs/postmortem%20Image%20Interpretation%20Guideline%202015%20in%20Japan%20(Italian).pdf

    • Related Report
      2017 Research-status Report

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Published: 2016-04-21   Modified: 2022-02-21  

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