| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Outline of Final Research Achievements |
Phosphorus magnetic resonance spectroscopy (31P-MRS) can provide useful information about phosphorus metabolism in various human tissues, but reports on physiological changes in the liver are lacking. We assessed phosphorus metabolites in the liver by 31P-MRS using three-dimensional chemical-shift imaging (3D-CSI). Healthy volunteers were assessed by 31P-MRS using 3D-CSI on a 3T MRI. The ratio of the peak area: total phosphorus signal was calculated, and significant changes inβ-ATP were evaluated.In the of β-ATP, a significant increase was observed after diet.31P-MRS with 3D-CSI can assess the major phosphorus metabolites in the liver and capture changes in their levels. This method is not burdensome, non-invasive, and can provide new information.
|
