| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
We investigated the metabolic effects of intraoperative administration of glucose and amino acids during laparoscopic colorectal cancer surgery. Methods: We randomly assigned patients to receive intravenous fluids with (GA group) or without (C group) glucose (75 g/L) and amino acids (30 g/L) using at 60 mL/h after anaesthesia induction. We took measurements before (TI) and after (T2) surgery during general anaesthesia. Results: Ketone body levels were significantly higher in the C group than in the GA group at T2. During anaesthesia, the nitrogen balance in the GA group was significantly higher than that in the C group. At T2, the urine 3 methyl histidine/urine creatinine ratios were similar between the GA and C groups. Conclusions: Ketone body levels were considerably higher in the control group than in the nutrition group after surgery. The nitrogen balance in the nutrition group was significantly higher than that in the control group.
|
