| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
It is critical to clarify the molecular mechanism of colitic caner for improving the prognosis of ulcerative colitis. We have elucidated the impact of extra-pulmonary surfactant protein d (SP-D) on UC. This experiment aims for clarifying the correlation of SP-D with colitic caner.
Comparing SP-D knockout (KO) mouse and wild mouse by using colitic caner mouse model with dextran sulphate sodium and azoxymethane, higher incidence and more number of tumor were observed in SP-D KO mouse. Consequently, SP-D is suggested to play a role on colitic cancer.
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