| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
The aim of this study was to evaluate the mechanisms of early brain injury after aneurysmal subarachnoid hemorrhage (SAH). This study demonstrated that there was a significant correlation between duration of depolarization and histological injuries in neurons and, also revealed that the duration of electroencephalography (EEG) suppression and the duration of depolarization were closed related. The duration of depolarization and the duration of suppression of EEG that induce ischemic cell changes in 50% of the neurons, were estimated at about 16 minutes and 54 minutes, respectively. These findings can contribute to a novel treatment of SAH and to a prediction of patients’ prognosis in a clinical setting.
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